Dihydroactinidiolide

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    17092-92-1

    Molecular formula
    C11H16O2

    SMILES
    C[C@@]12CCCC(C1=CC(=O)O2)(C)C

    Safety labels

    Acute Toxic
    Acute Toxic

  • Odor profile

    Fruity 74.8%
    Woody 69.33%
    Sweet 67.25%
    Floral 66.44%
    Berry 56.55%
    Tobacco 56.41%
    Powdery 48.91%
    Raspberry 43.8%
    Plum 38.35%
    Dry 35.38%

    Scent© AI

  • Properties

    XLogP3-AA
    2.2

    Molecular weight
    180.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    308°C

    Flash point est.
    144.51 ˚C

    Solubility expt.

    • Insoluble in water; soluble in nonpolar solvents
    • soluble (in ethanol)

  • Synonyms

    • 17092-92-1
    • DIHYDROACTINIDIOLIDE
    • Actinidiolide, dihydro-
    • 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (7aR)-
    • R-DIHYDROACTINIDIOLIDE
    • (R)-DIHYDROACTINIDIOLIDE
    • 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (R)-
    • O3M4862R3R
    • NSC 357087
    • UNII-O3M4862R3R
    • DIHYDROACTINIDIOLIDE, (-)-
    • NSC-357087
    • (7aR)-4,4,7a-trimethyl-6,7-dihydro-5H-1-benzofuran-2-one
    • (R)-4,4,7a-Trimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one
    • dihydroactinidolide
    • (-)-Dihydroactinidiolide; 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (7aR)- (9CI, ACI); (7aR)-5,6,7,7a-Tetrahydro-4,4,7a-trimethyl-2(4H)-benzofuranone (ACI); 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl- (8CI); 2(4H)-Benzofur
    • D-DIHYDROACTINIDIOLIDE
    • SCHEMBL2186328
    • (-)-DIHYDROACTINIDIOLIDE
    • CHEMBL2271637
    • DTXSID801028845
    • DIHYDROACTINIDIOLIDE (R)-FORM
    • MFCD20926295
    • s3962
    • AKOS028109299
    • BZ-6005
    • CCG-266435
    • SB45270
    • DIHYDROACTINIDIOLIDE (R)-FORM [MI]
    • HY-107805
    • CS-0030680
    • E77016
    • Q5276417
    • 5,6,7,7a-Tetrahydro-4,4-7a-trimethyl-2-(4H)-benzofuranone
    • 2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl- (VAN)
    • 4,4,7a-Trimethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one, (R)-

  • Applications

    Dihydroactinidiolide (CAS 17092-92-1) is a tea‑, woody‑ and amber‑toned norisoprenoid widely used in flavors and fragrances: it enriches warm, dry, clean facets in tea, floral, fougère, chypre and tobacco accords; serves as a modifier and soft fixative to add depth and diffusion in fine fragrances, body sprays, soaps, shampoos, detergents, candles and home‑care; in foods it boosts tea, honey, caramel, dairy, fruit and confectionery notes with good aroma stability through baking and pasteurization; it is employed as a GC‑MS reference/marker to trace carotenoid degradation and for quality control of tea, tobacco, coffee and baked goods; it is also a target for sustainable bioproduction from carotenoids via enzymes/microbes; limited in‑vitro studies suggest sensory‑relevant antioxidant/anti‑inflammatory effects, but its current role is chiefly F&F, subject to safety and labeling compliance.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 124.51
    methanol 173.43
    isopropanol 103.73
    water 1.59
    ethyl acetate 202.23
    n-propanol 112.06
    acetone 198.08
    n-butanol 91.26
    acetonitrile 265.73
    DMF 338.55
    toluene 183.25
    isobutanol 85.46
    1,4-dioxane 471.92
    methyl acetate 214.63
    THF 517.43
    2-butanone 170.9
    n-pentanol 62.46
    sec-butanol 86.17
    n-hexane 12.56
    ethylene glycol 53.86
    NMP 316.27
    cyclohexane 31.66
    DMSO 196.05
    n-butyl acetate 125.17
    n-octanol 81.05
    chloroform 651.67
    n-propyl acetate 84.95
    acetic acid 124.45
    dichloromethane 444.31
    cyclohexanone 240.48
    propylene glycol 60.98
    isopropyl acetate 132.87
    DMAc 244.46
    2-ethoxyethanol 97.67
    isopentanol 83.76
    n-heptane 10.91
    ethyl formate 111.39
    1,2-dichloroethane 247.79
    n-hexanol 142.53
    2-methoxyethanol 218.71
    isobutyl acetate 69.69
    tetrachloromethane 73.55
    n-pentyl acetate 98.28
    transcutol 443.58
    n-heptanol 70.09
    ethylbenzene 78.72
    MIBK 106.0
    2-propoxyethanol 249.78
    tert-butanol 125.9
    MTBE 107.75
    2-butoxyethanol 124.42
    propionic acid 116.34
    o-xylene 99.27
    formic acid 77.28
    diethyl ether 137.45
    m-xylene 136.54
    p-xylene 96.24
    chlorobenzene 208.2
    dimethyl carbonate 121.0
    n-octane 7.0
    formamide 105.69
    cyclopentanone 300.05
    2-pentanone 138.91
    anisole 152.43
    cyclopentyl methyl ether 212.22
    gamma-butyrolactone 367.16
    1-methoxy-2-propanol 204.0
    pyridine 301.07
    3-pentanone 125.91
    furfural 276.77
    n-dodecane 8.89
    diethylene glycol 207.14
    diisopropyl ether 57.2
    tert-amyl alcohol 94.97
    acetylacetone 205.88
    n-hexadecane 10.42
    acetophenone 123.43
    methyl propionate 180.15
    isopentyl acetate 117.64
    trichloroethylene 471.9
    n-nonanol 73.58
    cyclohexanol 115.27
    benzyl alcohol 99.36
    2-ethylhexanol 73.18
    isooctanol 55.59
    dipropyl ether 71.2
    1,2-dichlorobenzene 175.87
    ethyl lactate 64.72
    propylene carbonate 186.08
    n-methylformamide 191.62
    2-pentanol 70.53
    n-pentane 12.93
    1-propoxy-2-propanol 151.75
    1-methoxy-2-propyl acetate 179.53
    2-(2-methoxypropoxy) propanol 143.09
    mesitylene 80.5
    ε-caprolactone 221.84
    p-cymene 49.84
    epichlorohydrin 379.04
    1,1,1-trichloroethane 235.26
    2-aminoethanol 89.36
    morpholine-4-carbaldehyde 345.24
    sulfolane 290.27
    2,2,4-trimethylpentane 8.61
    2-methyltetrahydrofuran 296.87
    n-hexyl acetate 158.73
    isooctane 9.2
    2-(2-butoxyethoxy)ethanol 188.34
    sec-butyl acetate 75.45
    tert-butyl acetate 129.84
    decalin 18.95
    glycerin 97.96
    diglyme 282.51
    acrylic acid 113.75
    isopropyl myristate 67.86
    n-butyric acid 131.47
    acetyl acetate 154.5
    di(2-ethylhexyl) phthalate 68.77
    ethyl propionate 101.59
    nitromethane 281.14
    1,2-diethoxyethane 142.46
    benzonitrile 164.37
    trioctyl phosphate 52.75
    1-bromopropane 145.27
    gamma-valerolactone 364.11
    n-decanol 55.83
    triethyl phosphate 55.92
    4-methyl-2-pentanol 57.86
    propionitrile 180.97
    vinylene carbonate 196.48
    1,1,2-trichlorotrifluoroethane 202.89
    DMS 171.17
    cumene 53.98
    2-octanol 52.95
    2-hexanone 85.99
    octyl acetate 84.05
    limonene 60.5
    1,2-dimethoxyethane 189.03
    ethyl orthosilicate 55.04
    tributyl phosphate 62.13
    diacetone alcohol 139.33
    N,N-dimethylaniline 101.14
    acrylonitrile 232.93
    aniline 161.07
    1,3-propanediol 113.23
    bromobenzene 228.6
    dibromomethane 306.09
    1,1,2,2-tetrachloroethane 345.08
    2-methyl-cyclohexyl acetate 87.32
    tetrabutyl urea 81.5
    diisobutyl methanol 45.93
    2-phenylethanol 148.39
    styrene 90.1
    dioctyl adipate 82.18
    dimethyl sulfate 163.39
    ethyl butyrate 84.37
    methyl lactate 106.13
    butyl lactate 82.22
    diethyl carbonate 66.34
    propanediol butyl ether 120.25
    triethyl orthoformate 70.64
    p-tert-butyltoluene 49.94
    methyl 4-tert-butylbenzoate 128.72
    morpholine 400.24
    tert-butylamine 81.08
    n-dodecanol 43.21
    dimethoxymethane 271.74
    ethylene carbonate 165.3
    cyrene 119.86
    2-ethoxyethyl acetate 152.77
    2-ethylhexyl acetate 97.81
    1,2,4-trichlorobenzene 198.37
    4-methylpyridine 274.98
    dibutyl ether 71.92
    2,6-dimethyl-4-heptanol 45.93
    DEF 150.03
    dimethyl isosorbide 228.51
    tetrachloroethylene 207.34
    eugenol 130.69
    triacetin 129.28
    span 80 113.71
    1,4-butanediol 43.32
    1,1-dichloroethane 248.18
    2-methyl-1-pentanol 62.78
    methyl formate 160.41
    2-methyl-1-butanol 76.96
    n-decane 13.31
    butyronitrile 144.49
    3,7-dimethyl-1-octanol 79.67
    1-chlorooctane 58.44
    1-chlorotetradecane 27.01
    n-nonane 11.93
    undecane 10.81
    tert-butylcyclohexane 15.81
    cyclooctane 12.75
    cyclopentanol 134.12
    tetrahydropyran 296.98
    tert-amyl methyl ether 84.22
    2,5,8-trioxanonane 218.75
    1-hexene 44.54
    2-isopropoxyethanol 83.04
    2,2,2-trifluoroethanol 77.3
    methyl butyrate 103.2

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Amomum ptycholimatum Amomum ptycholimatum D. Fang, fam. Zingiberaceae 2.7%