Dihexyldecyl lauroyl glutamate

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  • Identifiers

    CAS number
    172944-28-4

    Molecular formula
    C49H95NO5

    SMILES
    CCCCCCCCCCCC(=O)N[C@@H](CCC(=O)OCC(CCCCCC)CCCCCCCC)C(=O)OCC(CCCCCC)CCCCCCCC

    Safety labels

  • Odor profile

    Fragrance
    Waxy 51.79%
    Oily 41.92%
    Fatty 40.9%
    Odorless 33.4%
    Woody 26.94%
    Herbal 25.09%
    Savory 22.87%
    Milky 22.62%
    Fresh 21.94%
    Lactonic 20.27%

     

    Flavor
    Bland 41.49%
    Mild 34.95%
    Odorless 30.56%
    Faint 30.16%
    Waxy 27.66%
    Fatty 26.05%
    Oily 24.13%
    Slightly waxy 22.68%
    Delicate 20.95%
    Bay oil 20.89%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    19.8

    pKa est.
    8.82 (weak base)

    Molecular weight
    778.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    672°C

    Flash point

    • 262.28 ˚C est.

  • Synonyms

    • Dihexyldecyl Lauroyl Glutamate
    • Amiter LG-1600
    • UNII-72WI6RFE4H
    • 72WI6RFE4H
    • Di-(2-hexyldecyl)-N-lauroyl-L-glutamate
    • Dihexyldecyl lauroyl glutamate [INCI]
    • 172944-28-4
    • N-Lauroyl-L-glutamic acid 2-hexyldecyl ester (1:2)
    • L-Glutamic acid, N-(1-oxododecyl)-, 1,5-bis(2-hexyldecyl) ester
    • DTXSID50169439
    • RefChem:133671
    • DTXCID0091930
    • (+-)-DIHEXYLDECYL LAUROYL GLUTAMATE
    • (+/-)-Dihexyldecyl lauroyl glutamate
    • WELLEIPLAKZPQH-DZJLPJKCSA-N
    • Bis(2-hexyldecyl) N-dodecanoyl-L-glutamate
    • Q21547042
    • 172944-28-4

  • Applications

    Dihexyldecyl lauroyl glutamate, CAS 172944-28-4, is an amino acid–based surfactant primarily used as a mild surfactant and emulsifier in cosmetics and personal care products; it also serves as a conditioning agent for hair and skin formulations, improving slip and a smooth feel. In addition, the ingredient can function as an emulsifier/stabilizer in oil-in-water systems and may be used as an excipient or formulation aid in pharmaceutical or nutraceutical products; it can also be applied in household cleaning formulations as a mild surfactant to reduce irritation for consumer products.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 11.31
    methanol 13.7
    isopropanol 11.54
    water 0.46
    ethyl acetate 111.25
    n-propanol 19.66
    acetone 71.6
    n-butanol 19.5
    acetonitrile 24.72
    DMF 136.08
    toluene 55.35
    isobutanol 17.68
    1,4-dioxane 86.08
    methyl acetate 90.76
    THF 200.83
    2-butanone 102.24
    n-pentanol 21.42
    sec-butanol 26.03
    n-hexane 9.01
    ethylene glycol 2.75
    NMP 572.87
    cyclohexane 18.05
    DMSO 116.26
    n-butyl acetate 79.78
    n-octanol 28.83
    chloroform 288.86
    n-propyl acetate 94.79
    acetic acid 86.81
    dichloromethane 267.66
    cyclohexanone 251.91
    propylene glycol 7.97
    isopropyl acetate 94.98
    DMAc 413.86
    2-ethoxyethanol 52.42
    isopentanol 20.59
    n-heptane 6.66
    ethyl formate 54.66
    1,2-dichloroethane 142.91
    n-hexanol 17.42
    2-methoxyethanol 48.15
    isobutyl acetate 59.05
    tetrachloromethane 69.28
    n-pentyl acetate 148.68
    transcutol 257.95
    n-heptanol 25.2
    ethylbenzene 36.4
    MIBK 64.91
    2-propoxyethanol 51.65
    tert-butanol 17.87
    MTBE 53.11
    2-butoxyethanol 76.73
    propionic acid 67.02
    o-xylene 60.44
    formic acid 24.63
    diethyl ether 41.09
    m-xylene 42.56
    p-xylene 47.9
    chlorobenzene 98.29
    dimethyl carbonate 76.24
    n-octane 4.34
    formamide 39.3
    cyclopentanone 284.02
    2-pentanone 89.79
    anisole 63.54
    cyclopentyl methyl ether 129.67
    gamma-butyrolactone 360.98
    1-methoxy-2-propanol 53.82
    pyridine 124.83
    3-pentanone 108.16
    furfural 257.17
    n-dodecane 2.36
    diethylene glycol 21.16
    diisopropyl ether 23.7
    tert-amyl alcohol 41.04
    acetylacetone 156.09
    n-hexadecane 2.79
    acetophenone 112.72
    methyl propionate 117.98
    isopentyl acetate 81.29
    trichloroethylene 360.16
    n-nonanol 30.06
    cyclohexanol 50.3
    benzyl alcohol 41.45
    2-ethylhexanol 20.7
    isooctanol 26.07
    dipropyl ether 39.8
    1,2-dichlorobenzene 132.65
    ethyl lactate 57.35
    propylene carbonate 228.11
    n-methylformamide 58.98
    2-pentanol 20.99
    n-pentane 6.09
    1-propoxy-2-propanol 60.38
    1-methoxy-2-propyl acetate 112.58
    2-(2-methoxypropoxy) propanol 84.09
    mesitylene 29.48
    ε-caprolactone 310.5
    p-cymene 25.78
    epichlorohydrin 252.75
    1,1,1-trichloroethane 207.37
    2-aminoethanol 9.16
    morpholine-4-carbaldehyde 261.24
    sulfolane 594.85
    2,2,4-trimethylpentane 9.16
    2-methyltetrahydrofuran 165.57
    n-hexyl acetate 136.19
    isooctane 3.17
    2-(2-butoxyethoxy)ethanol 95.08
    sec-butyl acetate 84.76
    tert-butyl acetate 122.94
    decalin 12.76
    glycerin 16.03
    diglyme 222.91
    acrylic acid 61.76
    isopropyl myristate 37.64
    n-butyric acid 101.93
    acetyl acetate 111.87
    di(2-ethylhexyl) phthalate 45.45
    ethyl propionate 100.17
    nitromethane 171.43
    1,2-diethoxyethane 96.28
    benzonitrile 50.7
    trioctyl phosphate 30.08
    1-bromopropane 73.29
    gamma-valerolactone 385.02
    n-decanol 17.59
    triethyl phosphate 72.5
    4-methyl-2-pentanol 15.16
    propionitrile 28.44
    vinylene carbonate 189.33
    1,1,2-trichlorotrifluoroethane 242.17
    DMS 124.74
    cumene 26.36
    2-octanol 25.0
    2-hexanone 81.59
    octyl acetate 53.66
    limonene 43.02
    1,2-dimethoxyethane 97.79
    ethyl orthosilicate 65.59
    tributyl phosphate 44.29
    diacetone alcohol 95.79
    N,N-dimethylaniline 59.65
    acrylonitrile 36.55
    aniline 52.03
    1,3-propanediol 16.14
    bromobenzene 117.21
    dibromomethane 154.67
    1,1,2,2-tetrachloroethane 330.93
    2-methyl-cyclohexyl acetate 86.43
    tetrabutyl urea 65.12
    diisobutyl methanol 14.65
    2-phenylethanol 34.45
    styrene 38.85
    dioctyl adipate 74.53
    dimethyl sulfate 199.45
    ethyl butyrate 90.97
    methyl lactate 71.12
    butyl lactate 112.51
    diethyl carbonate 60.58
    propanediol butyl ether 63.17
    triethyl orthoformate 87.91
    p-tert-butyltoluene 25.14
    methyl 4-tert-butylbenzoate 154.37
    morpholine 110.13
    tert-butylamine 12.73
    n-dodecanol 11.04
    dimethoxymethane 81.52
    ethylene carbonate 154.14
    cyrene 118.16
    2-ethoxyethyl acetate 193.41
    2-ethylhexyl acetate 76.39
    1,2,4-trichlorobenzene 187.57
    4-methylpyridine 127.74
    dibutyl ether 49.42
    2,6-dimethyl-4-heptanol 14.65
    DEF 164.28
    dimethyl isosorbide 176.29
    tetrachloroethylene 206.65
    eugenol 97.88
    triacetin 220.77
    span 80 78.17
    1,4-butanediol 10.09
    1,1-dichloroethane 128.88
    2-methyl-1-pentanol 27.51
    methyl formate 54.07
    2-methyl-1-butanol 27.78
    n-decane 5.85
    butyronitrile 27.9
    3,7-dimethyl-1-octanol 26.55
    1-chlorooctane 31.5
    1-chlorotetradecane 8.78
    n-nonane 5.38
    undecane 3.45
    tert-butylcyclohexane 9.5
    cyclooctane 8.64
    cyclopentanol 53.81
    tetrahydropyran 107.39
    tert-amyl methyl ether 77.47
    2,5,8-trioxanonane 123.11
    1-hexene 22.37
    2-isopropoxyethanol 46.22
    2,2,2-trifluoroethanol 70.05
    methyl butyrate 126.94

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction