Diglyceryl tetrastearate

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  • Identifiers

    CAS number
    72347-89-8

    Molecular formula
    C78H150O9

    SMILES
    CCCCCCCCCCCCCCCCCC(=O)OCC(COCC(COC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC

    Safety labels

  • Odor profile

    Fragrance
    Waxy 73.05%
    Fatty 60.58%
    Oily 44.82%
    Odorless 38.51%
    Creamy 21.04%
    Sweet 18.7%
    Alcoholic 16.94%
    Buttery 15.82%
    Dairy 14.93%
    Milky 14.91%

     

    Flavor
    Waxy 51.99%
    Fatty 44.45%
    Mild 43.92%
    Bland 40.3%
    Oily 39.81%
    Faint 32.95%
    Odorless 28.4%
    Fat 26.21%
    Slightly waxy 24.49%
    Soapy 23.41%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    33.4

    pKa est.
    13.5 (strong base)

    Molecular weight
    1232.0 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    667°C

    Flash point

    • 340.17 ˚C est.

  • Synonyms

    • Diglyceryl tetrastearate
    • NP0UUB6V8K
    • Diglycerol tetrastearate
    • Octadecanoic acid, tetraester with oxybis(propanediol)
    • DIGLYCERIN TETRASTEARATE
    • Octadecanoic acid, tetraester with diglycerol
    • DTXSID001021514
    • Octadecanoic acid, tetraester with oxybis[propanediol]
    • RefChem:587620
    • DTXCID801506530
    • 615-754-1
    • 72347-89-8
    • UNII-NP0UUB6V8K
    • [3-[2,3-di(octadecanoyloxy)propoxy]-2-octadecanoyloxypropyl] octadecanoate
    • SCHEMBL29360150
    • PSQZURIOAGQANZ-UHFFFAOYSA-N
    • 72347-89-8

  • Applications

    Diglyceryl tetrastearate (CAS 72347-89-8) is commonly used as an emollient and thickener/structuring agent in cosmetics and personal care formulations (creams, lotions, and lip products). It also serves as a lubricating/processing aid in polymers and coatings, acting as a plasticizer or slip additive to improve processing and final texture. In pharmaceutical contexts, it can function as a vehicle or excipient for topical semisolid dosage forms. Additionally, because of its stearate ester nature, it may be used as a conditioning or lubricating component in certain cleaning and household product formulations to improve spreadability and feel.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 12.38
    methanol 16.55
    isopropanol 13.35
    water 0.68
    ethyl acetate 161.4
    n-propanol 22.85
    acetone 114.01
    n-butanol 20.05
    acetonitrile 47.42
    DMF 225.85
    toluene 65.76
    isobutanol 20.25
    1,4-dioxane 112.01
    methyl acetate 144.42
    THF 243.46
    2-butanone 142.69
    n-pentanol 23.1
    sec-butanol 28.1
    n-hexane 8.31
    ethylene glycol 4.13
    NMP 781.21
    cyclohexane 18.92
    DMSO 222.57
    n-butyl acetate 95.33
    n-octanol 25.3
    chloroform 416.74
    n-propyl acetate 127.27
    acetic acid 132.16
    dichloromethane 420.76
    cyclohexanone 319.57
    propylene glycol 9.47
    isopropyl acetate 125.35
    DMAc 593.49
    2-ethoxyethanol 62.07
    isopentanol 20.88
    n-heptane 6.35
    ethyl formate 88.35
    1,2-dichloroethane 219.57
    n-hexanol 15.64
    2-methoxyethanol 58.01
    isobutyl acetate 69.88
    tetrachloromethane 98.39
    n-pentyl acetate 155.43
    transcutol 228.62
    n-heptanol 21.11
    ethylbenzene 42.34
    MIBK 77.58
    2-propoxyethanol 53.66
    tert-butanol 21.46
    MTBE 55.18
    2-butoxyethanol 72.15
    propionic acid 95.93
    o-xylene 72.84
    formic acid 39.15
    diethyl ether 46.26
    m-xylene 48.82
    p-xylene 61.31
    chlorobenzene 131.8
    dimethyl carbonate 124.11
    n-octane 4.48
    formamide 66.62
    cyclopentanone 401.59
    2-pentanone 116.92
    anisole 79.26
    cyclopentyl methyl ether 148.68
    gamma-butyrolactone 555.95
    1-methoxy-2-propanol 60.96
    pyridine 185.47
    3-pentanone 145.86
    furfural 397.73
    n-dodecane 2.63
    diethylene glycol 25.45
    diisopropyl ether 25.55
    tert-amyl alcohol 42.19
    acetylacetone 248.44
    n-hexadecane 3.11
    acetophenone 153.82
    methyl propionate 168.73
    isopentyl acetate 87.43
    trichloroethylene 556.8
    n-nonanol 26.78
    cyclohexanol 52.34
    benzyl alcohol 52.09
    2-ethylhexanol 19.42
    isooctanol 21.66
    dipropyl ether 45.05
    1,2-dichlorobenzene 192.05
    ethyl lactate 81.48
    propylene carbonate 328.1
    n-methylformamide 103.85
    2-pentanol 20.71
    n-pentane 5.77
    1-propoxy-2-propanol 59.91
    1-methoxy-2-propyl acetate 126.52
    2-(2-methoxypropoxy) propanol 87.53
    mesitylene 35.09
    ε-caprolactone 373.9
    p-cymene 29.91
    epichlorohydrin 375.42
    1,1,1-trichloroethane 339.3
    2-aminoethanol 12.14
    morpholine-4-carbaldehyde 346.82
    sulfolane 913.08
    2,2,4-trimethylpentane 7.87
    2-methyltetrahydrofuran 196.07
    n-hexyl acetate 138.12
    isooctane 3.03
    2-(2-butoxyethoxy)ethanol 87.0
    sec-butyl acetate 105.22
    tert-butyl acetate 151.76
    decalin 13.58
    glycerin 20.51
    diglyme 229.09
    acrylic acid 98.51
    isopropyl myristate 41.71
    n-butyric acid 130.6
    acetyl acetate 190.79
    di(2-ethylhexyl) phthalate 50.32
    ethyl propionate 146.22
    nitromethane 344.12
    1,2-diethoxyethane 98.53
    benzonitrile 77.69
    trioctyl phosphate 33.65
    1-bromopropane 96.34
    gamma-valerolactone 506.97
    n-decanol 16.25
    triethyl phosphate 90.72
    4-methyl-2-pentanol 14.4
    propionitrile 49.39
    vinylene carbonate 298.23
    1,1,2-trichlorotrifluoroethane 337.02
    DMS 161.25
    cumene 30.64
    2-octanol 20.71
    2-hexanone 104.83
    octyl acetate 58.03
    limonene 47.12
    1,2-dimethoxyethane 128.11
    ethyl orthosilicate 76.72
    tributyl phosphate 51.55
    diacetone alcohol 115.8
    N,N-dimethylaniline 72.77
    acrylonitrile 71.96
    aniline 65.83
    1,3-propanediol 18.82
    bromobenzene 159.72
    dibromomethane 219.94
    1,1,2,2-tetrachloroethane 493.29
    2-methyl-cyclohexyl acetate 98.02
    tetrabutyl urea 74.91
    diisobutyl methanol 14.16
    2-phenylethanol 38.12
    styrene 47.26
    dioctyl adipate 86.56
    dimethyl sulfate 346.45
    ethyl butyrate 114.47
    methyl lactate 101.19
    butyl lactate 114.6
    diethyl carbonate 83.34
    propanediol butyl ether 57.18
    triethyl orthoformate 99.6
    p-tert-butyltoluene 27.73
    methyl 4-tert-butylbenzoate 176.48
    morpholine 137.8
    tert-butylamine 14.45
    n-dodecanol 10.68
    dimethoxymethane 112.64
    ethylene carbonate 232.86
    cyrene 149.97
    2-ethoxyethyl acetate 217.47
    2-ethylhexyl acetate 80.38
    1,2,4-trichlorobenzene 259.14
    4-methylpyridine 166.56
    dibutyl ether 49.57
    2,6-dimethyl-4-heptanol 14.16
    DEF 210.21
    dimethyl isosorbide 198.19
    tetrachloroethylene 294.3
    eugenol 110.18
    triacetin 266.51
    span 80 72.0
    1,4-butanediol 12.53
    1,1-dichloroethane 196.75
    2-methyl-1-pentanol 27.59
    methyl formate 102.81
    2-methyl-1-butanol 27.38
    n-decane 6.12
    butyronitrile 40.35
    3,7-dimethyl-1-octanol 24.21
    1-chlorooctane 32.95
    1-chlorotetradecane 9.98
    n-nonane 5.69
    undecane 3.71
    tert-butylcyclohexane 9.5
    cyclooctane 8.8
    cyclopentanol 66.53
    tetrahydropyran 124.61
    tert-amyl methyl ether 75.28
    2,5,8-trioxanonane 132.55
    1-hexene 22.28
    2-isopropoxyethanol 52.21
    2,2,2-trifluoroethanol 112.88
    methyl butyrate 180.49

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction