Diethylene glycol monomethyl ether

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  • Identifiers

    CAS number
    111-77-3

    Molecular formula
    C5H12O3

    SMILES
    COCCOCCO

    Safety labels

    Health Hazard
    Health

    Retention indicies (RI)

    • Carbowax: 1321.0

  • Odor profile

    Ethereal 51.21%
    Alcoholic 47.38%
    Odorless 42.38%
    Solvent 30.43%
    Sweet 25.66%
    Fermented 20.78%
    Musty 20.06%
    Oily 19.49%
    Fruity 17.99%
    Fishy 17.97%

    Scent© AI

  • Properties

    XLogP3-AA
    -0.9

    Molecular weight
    120.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Melting point expt.

    • -94 °F (NTP, 1992)
    • Less than -84 °C
    • -94 °F

    Boiling point

    • 381 °F at 760 mmHg (NTP, 1992)
    • 193 °C
    • 381 °F

    Flash point est.
    84.26 ˚C

    Flash point expt.

    • 200 °F (NTP, 1992)
    • 205 °F (96 °C) (open cup)
    • 93 °C o.c.
    • 200 °F

    Solubility expt.

    • greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)
    • Miscible /1X10+6 mg/L/ with water
    • Miscible with alcohol, glycerol, ether, acetone, dimethylformamide
    • Very soluble in ethanol, ethyl ether
    • SOL IN ALL PROPN IN BENZENE
    • Solubility in water: very good

  • Synonyms

    • 2-(2-Methoxyethoxy)ethanol
    • 111-77-3
    • DIETHYLENE GLYCOL MONOMETHYL ETHER
    • Methyl carbitol
    • Methoxydiglycol
    • Methyl digol
    • Ethanol, 2-(2-methoxyethoxy)-
    • Dowanol DM
    • Methyl dioxitol
    • 3,6-Dioxa-1-heptanol
    • DEGME
    • MECB
    • Ektasolve DM
    • Diethylene glycol methyl ether
    • Diglycol monomethyl ether
    • Methyl-PEG2-alcohol
    • Jeffersol DM
    • 2-(2-Methoxyethoxy)-Ethanol
    • Dowanol 16
    • Methyldiglycol
    • Diethyleneglycol monomethyl ether
    • Methyl karbitol
    • Caswell No. 338B
    • EGME, di-
    • Ethylene diglycol monomethyl ether
    • HSDB 96
    • methylcarbitol
    • DTXSID3025049
    • NSC 2261
    • EINECS 203-906-6
    • UNII-465DDJ8G8K
    • EPA Pesticide Chemical Code 042204
    • BRN 1697812
    • 465DDJ8G8K
    • 2-(2-methoxyethoxy)ethan-1-ol
    • CHEBI:44836
    • Ethanol, 2,2'-oxybis-, monomethyl ether
    • AI3-18364
    • NSC-2261
    • 2-(Methoxyethoxy)ethanol
    • 2-(2-methoxy ethoxy) ethanol
    • DTXCID305049
    • .beta.-Methoxy-.beta.'-hydroxydiethyl ether
    • EC 203-906-6
    • 4-01-00-02392 (Beilstein Handbook Reference)
    • NCGC00163771-03
    • DIETHYLENE GLYCOL MONOMETHYL ETHER [MI]
    • DIETHYLENE GLYCOL MONOMETHYL ETHER [HSDB]
    • Methyl karbitol [Czech]
    • Glycol Ether DM
    • PG0
    • mPEG2-OH
    • beta-Methoxy-beta'-hydroxydiethyl ether
    • 2-(2-methoxy-ethoxy)ethanol
    • Hicotol CAR
    • PolySolv DM
    • diethylene glycol-monomethyl ether
    • 3,6Dioxa1heptanol
    • MFCD00002871
    • DGMME
    • EGME, di
    • 2-MEE cpd
    • 2(2Methoxyethoxy)ethanol
    • 2-(methoxyethoxy)-ethanol
    • Ethanol, 2(2methoxyethoxy)
    • 2-(2-methoxyethoxyl)ethanol
    • SCHEMBL15778
    • 2-(2'-methoxyethoxy)ethanol
    • METHYLDIETHYLENE GLYCOL
    • WLN: Q2O2O1
    • diethyleneglycol monomethylether
    • 2-BETA-METHYL CARBITOL
    • 2-(2'-methoxyethoxy) ethanol
    • 2-(2-methoxy-ethoxy)-ethanol
    • diethylene glycol monomethylether
    • CHEMBL1235250
    • NSC2261
    • m-PEG-OH, MW 2,000
    • m-PEG-OH, MW 5,000
    • betaMethoxybeta'hydroxydiethyl ether
    • m-PEG-OH, MW 30,000
    • Tox21_400009
    • Diethylene glycol methyl ether, 99%
    • STL280434
    • AKOS009156476
    • Ethanol,2'-oxybis-, monomethyl ether
    • CS-W013578
    • Ethanol, 2,2'oxybis, monomethyl ether
    • FM37064
    • HY-W012862
    • USEPA/OPP Pesticide Code: 042204
    • NCGC00163771-01
    • NCGC00163771-02
    • NCGC00163771-04
    • AS-12944
    • BP-13446
    • BP-23184
    • BP-23185
    • BP-27937
    • CAS-111-77-3
    • DA-55424
    • 2,2'-OXYBISETHANOL MONOMETHYL ETHER
    • M0537
    • NS00007314
    • EN300-56026
    • D78002
    • Q1925579
    • Diethylene glycol monomethyl ether (stabilized with BHT)
    • Z849748688
    • Diethylene glycol methyl ether, ReagentPlus(R), >=99.0%
    • Diethylene glycol methyl ether, SAJ first grade, >=99.0%
    • Diethylene glycol monomethyl ether, purum, >=99.0% (GC)
    • 2-(2-Methoxyethoxy)ethanol stabilized with ~100ppm 2,6-Di-tert-butyl-4-methylphenol

  • Applications

    Diethylene glycol monomethyl ether (DGME, CAS 111-77-3) is a high-boiling, slow-evaporating, water-miscible glycol ether solvent widely used as a coupling solvent and coalescent in waterborne paints and coatings to improve flow, wetting and adhesion; in printing and inkjet inks to control dry time, keep printheads hydrated and enhance gloss; in industrial and household cleaners, metal degreasers, paint and adhesive removers as a powerful coupling solvent that dissolves oils, resins, inks and waxes while bridging water-organic phases; in textile and leather processing as a dye carrier and leveling agent, penetrant and softener; in plastics and polymer work as a solvent and diluent for nitrocellulose, acrylics, epoxies, polyvinyl acetate and alkyd resins, and as a medium for electronic photoresist stripping and clean/etch steps; in agrochemical formulations as a solvent and penetration enhancer; in brake fluids, de-icing/anti-freeze and humectant uses thanks to its high boiling point and moisture retention; and in cosmetics and personal care (subject to applicable regulations) as a solvent, fragrance carrier and viscosity modifier, with further roles as a pigment dispersant, aroma fixative, selective extraction agent and additive for metalworking fluids, leveraging DGME’s strong solvency, low volatility and broad compatibility.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1127.01
    methanol 2885.61
    isopropanol 447.17
    water 354.99
    ethyl acetate 104.16
    n-propanol 646.92
    acetone 225.81
    n-butanol 354.47
    acetonitrile 283.47
    DMF 1222.87
    toluene 14.22
    isobutanol 270.69
    1,4-dioxane 420.86
    methyl acetate 171.39
    THF 345.95
    2-butanone 116.75
    n-pentanol 118.65
    sec-butanol 276.73
    n-hexane 5.48
    ethylene glycol 1319.34
    NMP 683.43
    cyclohexane 30.84
    DMSO 1717.74
    n-butyl acetate 53.68
    n-octanol 40.02
    chloroform 287.67
    n-propyl acetate 51.37
    acetic acid 2286.3
    dichloromethane 343.06
    cyclohexanone 229.1
    propylene glycol 763.99
    isopropyl acetate 33.77
    DMAc 487.94
    2-ethoxyethanol 422.89
    isopentanol 130.01
    n-heptane 11.14
    ethyl formate 201.35
    1,2-dichloroethane 194.41
    n-hexanol 94.63
    2-methoxyethanol 1207.3
    isobutyl acetate 23.62
    tetrachloromethane 68.81
    n-pentyl acetate 28.69
    transcutol 489.23
    n-heptanol 40.39
    ethylbenzene 7.59
    MIBK 20.5
    2-propoxyethanol 250.1
    tert-butanol 299.48
    MTBE 56.05
    2-butoxyethanol 117.92
    propionic acid 808.76
    o-xylene 17.16
    formic acid 2629.09
    diethyl ether 73.63
    m-xylene 10.79
    p-xylene 12.34
    chlorobenzene 41.05
    dimethyl carbonate 52.32
    n-octane 3.09
    formamide 2085.65
    cyclopentanone 273.05
    2-pentanone 57.46
    anisole 36.9
    cyclopentyl methyl ether 100.73
    gamma-butyrolactone 443.62
    1-methoxy-2-propanol 431.25
    pyridine 246.84
    3-pentanone 54.07
    furfural 489.15
    n-dodecane 2.68
    diethylene glycol 447.75
    diisopropyl ether 9.53
    tert-amyl alcohol 201.6
    acetylacetone 72.44
    n-hexadecane 2.87
    acetophenone 49.07
    methyl propionate 115.26
    isopentyl acetate 35.63
    trichloroethylene 315.29
    n-nonanol 33.08
    cyclohexanol 282.86
    benzyl alcohol 82.08
    2-ethylhexanol 42.53
    isooctanol 28.16
    dipropyl ether 44.25
    1,2-dichlorobenzene 51.57
    ethyl lactate 78.31
    propylene carbonate 165.97
    n-methylformamide 1072.76
    2-pentanol 103.56
    n-pentane 10.55
    1-propoxy-2-propanol 141.1
    1-methoxy-2-propyl acetate 58.93
    2-(2-methoxypropoxy) propanol 103.3
    mesitylene 8.64
    ε-caprolactone 205.56
    p-cymene 13.82
    epichlorohydrin 296.16
    1,1,1-trichloroethane 82.65
    2-aminoethanol 1314.94
    morpholine-4-carbaldehyde 616.18
    sulfolane 598.26
    2,2,4-trimethylpentane 5.11
    2-methyltetrahydrofuran 193.79
    n-hexyl acetate 43.18
    isooctane 2.15
    2-(2-butoxyethoxy)ethanol 144.46
    sec-butyl acetate 21.69
    tert-butyl acetate 28.85
    decalin 6.21
    glycerin 1142.71
    diglyme 293.99
    acrylic acid 893.89
    isopropyl myristate 15.77
    n-butyric acid 514.16
    acetyl acetate 71.0
    di(2-ethylhexyl) phthalate 32.42
    ethyl propionate 44.6
    nitromethane 1341.07
    1,2-diethoxyethane 61.27
    benzonitrile 76.28
    trioctyl phosphate 22.8
    1-bromopropane 60.55
    gamma-valerolactone 450.0
    n-decanol 22.97
    triethyl phosphate 39.89
    4-methyl-2-pentanol 27.2
    propionitrile 177.36
    vinylene carbonate 195.77
    1,1,2-trichlorotrifluoroethane 631.58
    DMS 51.75
    cumene 8.14
    2-octanol 20.05
    2-hexanone 33.33
    octyl acetate 25.62
    limonene 25.07
    1,2-dimethoxyethane 327.49
    ethyl orthosilicate 35.23
    tributyl phosphate 28.53
    diacetone alcohol 79.65
    N,N-dimethylaniline 35.56
    acrylonitrile 311.34
    aniline 115.88
    1,3-propanediol 1031.06
    bromobenzene 27.04
    dibromomethane 172.21
    1,1,2,2-tetrachloroethane 254.05
    2-methyl-cyclohexyl acetate 39.46
    tetrabutyl urea 44.2
    diisobutyl methanol 21.69
    2-phenylethanol 58.7
    styrene 12.3
    dioctyl adipate 41.36
    dimethyl sulfate 126.23
    ethyl butyrate 47.4
    methyl lactate 157.26
    butyl lactate 59.33
    diethyl carbonate 39.92
    propanediol butyl ether 139.79
    triethyl orthoformate 46.11
    p-tert-butyltoluene 13.77
    methyl 4-tert-butylbenzoate 59.25
    morpholine 663.91
    tert-butylamine 144.65
    n-dodecanol 17.84
    dimethoxymethane 216.21
    ethylene carbonate 146.18
    cyrene 125.07
    2-ethoxyethyl acetate 49.22
    2-ethylhexyl acetate 27.93
    1,2,4-trichlorobenzene 68.97
    4-methylpyridine 114.19
    dibutyl ether 26.76
    2,6-dimethyl-4-heptanol 21.69
    DEF 183.61
    dimethyl isosorbide 136.82
    tetrachloroethylene 263.67
    eugenol 80.38
    triacetin 74.73
    span 80 116.86
    1,4-butanediol 320.35
    1,1-dichloroethane 96.24
    2-methyl-1-pentanol 57.81
    methyl formate 547.35
    2-methyl-1-butanol 168.54
    n-decane 4.35
    butyronitrile 129.44
    3,7-dimethyl-1-octanol 31.26
    1-chlorooctane 14.91
    1-chlorotetradecane 6.32
    n-nonane 4.24
    undecane 3.22
    tert-butylcyclohexane 4.49
    cyclooctane 6.24
    cyclopentanol 368.31
    tetrahydropyran 240.91
    tert-amyl methyl ether 44.59
    2,5,8-trioxanonane 203.8
    1-hexene 15.05
    2-isopropoxyethanol 144.68
    2,2,2-trifluoroethanol 716.05
    methyl butyrate 76.42

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Osmanthus headspace (picked flowers) 1 68917-05-5 Osmanthus fragrans (Thunb.) Lour., fam. Oleaceae 1.04%