Diammonium Citrate

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  • Identifiers

    CAS number
    3012-65-5

    Molecular formula
    C6H14N2O7

    SMILES
    C(C(=O)[O-])C(CC(=O)[O-])(C(=O)O)O.[NH4+].[NH4+]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 65.04%
    Sweet 39.87%
    Sour 27.29%
    Caramellic 23.2%
    Buttery 22.32%
    Clean 21.89%
    Winey 20.82%
    Creamy 19.54%
    Savory 19.33%
    Fatty 18.72%

     

    Flavor
    Odorless 67.99%
    Very mild 36.17%
    Mild 30.69%
    Sour 28.3%
    Bland 24.63%
    Nutty 23.09%
    Yeast 22.41%
    Caramellic 22.35%
    Musty 22.27%
    Sweet-like 21.79%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    -0.58 (strong acid)

    Molecular weight
    226.18 g/mol

    Flash point

    • 188.34 ˚C est.

    Solubility expt.

    • Slightly soluble in alcohol
    • Soluble in about 1 part water

  • Synonyms

    • DIAMMONIUM CITRATE
    • 3012-65-5
    • Ammonium citrate dibasic
    • Microstop
    • Diammonium hydrogen citrate
    • Dibasic ammonium citrate
    • Ammonium monohydrogen citrate
    • AmmCitrate
    • Ammonium citrate, dibasic
    • citric acid diammonium salt
    • ammonium hydrogen citrate
    • Ammonium monohydrogencitrat
    • Ammonium monohydrogencitrate
    • Citric acid, diammonium salt
    • Diammonium citrate (secondary)
    • 2-Hydroxy-1,2,3-propanetricarboxylic acid, diammonium salt
    • diammonium 3-carboxy-3-hydroxypentanedioate
    • N9BUG430K8
    • 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, diammonium salt
    • CHEBI:63076
    • DTXCID5079
    • DA-H-C cpd
    • RefChem:586249
    • 221-146-3
    • DTXSID5020079
    • Citrate (diammonium)
    • MFCD00013068
    • Diammonium hydrogen 2-hydroxypropane-1,2,3-tricarboxylate
    • Ammonium hydrogencitrate
    • Citric acid ammonium salt
    • Ammonium monohydrogen citrate; Citrate diammonium hydrogen
    • HSDB 300
    • EINECS 221-146-3
    • UNII-N9BUG430K8
    • AI3-26173
    • Diammonium 2-hydroxy-1,2,3-propanetricarboxylate
    • Ammonium Citrate Dibasic ACS Granular
    • diazanium;3-carboxy-3-hydroxypentanedioate
    • DB-047712
    • 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, ammonium salt (1:2)
    • 3012-65-5

  • Applications

    Diammonium Citrate (CAS 3012-65-5) is widely used as a buffering agent and acidity regulator in food processing and beverage formulations, helping to control pH and product stability. In cosmetics and personal care, it functions as a pH adjuster and chelating agent to improve preservative efficacy and overall formulation stability. In household and industrial cleaning, it serves as a chelating/sequestering agent to soften water and enhance cleaning performance, and as a buffering component in various formulations. In pharmaceuticals, it is used as an excipient for buffering and stabilization of solutions and oral dosage forms. In polymer and coatings manufacturing, it can act as a processing aid and stabilizer, helping to control ionic strength and mitigate metal ion interference. In agriculture, it may be used as a nitrogen-containing source in fertilizer formulations or as a citrate source in hydroponic systems.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1693.77
    methanol 3852.29
    isopropanol 813.72
    water 1658.97
    ethyl acetate 97.75
    n-propanol 1074.54
    acetone 783.98
    n-butanol 482.61
    acetonitrile 259.05
    DMF 4787.84
    toluene 71.9
    isobutanol 440.98
    1,4-dioxane 487.8
    methyl acetate 185.3
    THF 1253.44
    2-butanone 369.2
    n-pentanol 313.48
    sec-butanol 497.12
    n-hexane 28.8
    ethylene glycol 1136.14
    NMP 1328.09
    cyclohexane 25.99
    DMSO 4729.18
    n-butyl acetate 34.55
    n-octanol 82.42
    chloroform 39.27
    n-propyl acetate 77.37
    acetic acid 221.28
    dichloromethane 117.62
    cyclohexanone 187.4
    propylene glycol 690.91
    isopropyl acetate 55.01
    DMAc 2032.07
    2-ethoxyethanol 1062.51
    isopentanol 241.16
    n-heptane 18.52
    ethyl formate 194.68
    1,2-dichloroethane 179.26
    n-hexanol 124.34
    2-methoxyethanol 1971.62
    isobutyl acetate 23.69
    tetrachloromethane 11.77
    n-pentyl acetate 31.92
    transcutol 317.19
    n-heptanol 76.5
    ethylbenzene 39.34
    MIBK 109.35
    2-propoxyethanol 421.83
    tert-butanol 642.0
    MTBE 192.14
    2-butoxyethanol 192.25
    propionic acid 207.45
    o-xylene 61.59
    formic acid 966.02
    diethyl ether 350.83
    m-xylene 47.33
    p-xylene 33.31
    chlorobenzene 18.0
    dimethyl carbonate 216.73
    n-octane 10.11
    formamide 1739.12
    cyclopentanone 409.32
    2-pentanone 240.08
    anisole 156.24
    cyclopentyl methyl ether 267.0
    gamma-butyrolactone 456.54
    1-methoxy-2-propanol 1056.37
    pyridine 231.6
    3-pentanone 193.65
    furfural 325.96
    n-dodecane 6.26
    diethylene glycol 477.94
    diisopropyl ether 48.74
    tert-amyl alcohol 402.79
    acetylacetone 152.69
    n-hexadecane 6.29
    acetophenone 99.85
    methyl propionate 229.82
    isopentyl acetate 21.6
    trichloroethylene 91.57
    n-nonanol 76.22
    cyclohexanol 172.17
    benzyl alcohol 157.87
    2-ethylhexanol 43.01
    isooctanol 44.97
    dipropyl ether 111.89
    1,2-dichlorobenzene 15.97
    ethyl lactate 96.51
    propylene carbonate 100.26
    n-methylformamide 2208.8
    2-pentanol 231.87
    n-pentane 49.13
    1-propoxy-2-propanol 190.23
    1-methoxy-2-propyl acetate 59.03
    2-(2-methoxypropoxy) propanol 138.27
    mesitylene 26.97
    ε-caprolactone 135.99
    p-cymene 15.58
    epichlorohydrin 515.23
    1,1,1-trichloroethane 27.08
    2-aminoethanol 1478.83
    morpholine-4-carbaldehyde 906.0
    sulfolane 696.7
    2,2,4-trimethylpentane 7.68
    2-methyltetrahydrofuran 373.28
    n-hexyl acetate 44.29
    isooctane 5.22
    2-(2-butoxyethoxy)ethanol 195.93
    sec-butyl acetate 33.24
    tert-butyl acetate 58.71
    decalin 7.6
    glycerin 758.17
    diglyme 365.4
    acrylic acid 210.66
    isopropyl myristate 23.64
    n-butyric acid 123.93
    acetyl acetate 28.06
    di(2-ethylhexyl) phthalate 22.95
    ethyl propionate 93.81
    nitromethane 582.08
    1,2-diethoxyethane 99.51
    benzonitrile 44.55
    trioctyl phosphate 24.75
    1-bromopropane 106.27
    gamma-valerolactone 494.47
    n-decanol 61.28
    triethyl phosphate 26.49
    4-methyl-2-pentanol 83.71
    propionitrile 255.69
    vinylene carbonate 109.19
    1,1,2-trichlorotrifluoroethane 217.88
    DMS 38.83
    cumene 22.52
    2-octanol 45.46
    2-hexanone 126.62
    octyl acetate 36.32
    limonene 22.19
    1,2-dimethoxyethane 1093.06
    ethyl orthosilicate 25.64
    tributyl phosphate 21.15
    diacetone alcohol 163.64
    N,N-dimethylaniline 157.48
    acrylonitrile 319.83
    aniline 142.57
    1,3-propanediol 852.04
    bromobenzene 12.39
    dibromomethane 73.85
    1,1,2,2-tetrachloroethane 83.15
    2-methyl-cyclohexyl acetate 25.95
    tetrabutyl urea 58.57
    diisobutyl methanol 25.51
    2-phenylethanol 65.94
    styrene 42.55
    dioctyl adipate 36.72
    dimethyl sulfate 333.83
    ethyl butyrate 42.98
    methyl lactate 232.37
    butyl lactate 42.79
    diethyl carbonate 27.34
    propanediol butyl ether 144.18
    triethyl orthoformate 34.63
    p-tert-butyltoluene 15.58
    methyl 4-tert-butylbenzoate 75.46
    morpholine 790.78
    tert-butylamine 308.99
    n-dodecanol 45.26
    dimethoxymethane 1657.81
    ethylene carbonate 89.94
    cyrene 200.35
    2-ethoxyethyl acetate 43.66
    2-ethylhexyl acetate 16.56
    1,2,4-trichlorobenzene 19.61
    4-methylpyridine 194.94
    dibutyl ether 52.03
    2,6-dimethyl-4-heptanol 25.51
    DEF 419.05
    dimethyl isosorbide 163.97
    tetrachloroethylene 62.83
    eugenol 94.72
    triacetin 40.36
    span 80 79.96
    1,4-butanediol 452.97
    1,1-dichloroethane 68.11
    2-methyl-1-pentanol 142.21
    methyl formate 1158.26
    2-methyl-1-butanol 272.59
    n-decane 11.13
    butyronitrile 159.98
    3,7-dimethyl-1-octanol 42.93
    1-chlorooctane 24.18
    1-chlorotetradecane 11.09
    n-nonane 11.85
    undecane 8.26
    tert-butylcyclohexane 5.65
    cyclooctane 12.4
    cyclopentanol 309.53
    tetrahydropyran 304.78
    tert-amyl methyl ether 168.54
    2,5,8-trioxanonane 275.82
    1-hexene 75.48
    2-isopropoxyethanol 376.91
    2,2,2-trifluoroethanol 162.68
    methyl butyrate 120.95

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction