Di-iso-amyl ether

Overview IFRA Request a quote

  • Identifiers

    CAS number
    544-01-4

    Molecular formula
    C10H22O

    SMILES
    CC(C)CCOCCC(C)C

    Safety labels

    Flammable
    Flammable

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Green 92.72%
    Ethereal 73.61%
    Fruity 71.53%
    Alcoholic 66.08%
    Fermented 65.05%
    Cognac 54.14%
    Cocoa 48.47%
    Herbal 43.11%
    Malty 41.1%
    Apple 40.76%

     

    Flavor
    Green 60.41%
    Fruity 57.82%
    Ethereal 36.17%
    Oily 29.6%
    Fermented 27.3%
    Earthy 27.1%
    Fresh 27.0%
    Floral 26.38%
    Herbal 26.3%
    Tropical 25.77%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    3.5

    pKa est.
    8.11 (weak base)

    Molecular weight
    158.28 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point

    • 172.5 °C

    Flash point

    • 48.03 ˚C est.

    Solubility expt.

    • MISCIBLE WITH ALCOHOL, CHLOROFORM, ETHER
    • Water solubility of 200 mg/l
    • Very soluble in acetone, chloroform, ethyl ether

  • Synonyms

    • Diisopentyl ether
    • Isoamyl ether
    • Diisoamyl ether
    • 544-01-4
    • Isopentyl ether
    • DI-ISO-AMYL ETHER
    • Isoamyl oxide
    • Butane, 1,1'-oxybis[3-methyl-
    • Di-3-methylbutyl ether
    • 3-methyl-1-(3-methylbutoxy)butane
    • 1,1'-Oxybis(3-methylbutane)
    • 1,1'-Oxylbis(3-methylbutane)
    • HSDB 2773
    • Butane, 1,1'-oxybis(3-methyl-
    • NSC 9281
    • EINECS 208-857-4
    • DTXSID8052198
    • UNII-5X9P91566R
    • AI3-02268
    • Butane, 1,1'-oxylbis(3-methyl-
    • NSC-9281
    • ISOAMYL ETHER [MI]
    • DTXCID3030769
    • DI-ISO-AMYL ETHER [HSDB]
    • EC 208-857-4
    • 5X9P91566R
    • i-pentylether
    • di-isoamyl ether
    • di-isopentyl ether
    • Di3methylbutyl ether
    • MFCD00008947
    • Isoamyl ether, 99%
    • di(3-methylbutyl) ether
    • 1,1'Oxybis(3methylbutane)
    • SCHEMBL42956
    • 1,1'Oxylbis(3methylbutane)
    • Butane, 1,1'oxybis(3methyl
    • Butane,1'-oxybis[3-methyl-
    • NSC9281
    • CHEBI:183294
    • 1-(Isopentyloxy)-3-methylbutane #
    • Tox21_303780
    • STL280333
    • AKOS009031402
    • NCGC00357071-01
    • CAS-544-01-4
    • LS-13910
    • DB-052564
    • I0086
    • NS00005010
    • Q22829647

  • Applications

    Di-iso-amyl ether (CAS 544-01-4) is primarily used as a non-polar, high-boiling solvent and processing aid in industrial manufacturing. It serves as a solvent and reaction medium in coatings, inks, and adhesives, helping dissolve resins and facilitate formulation and processing. It may function as a carrier or solvent in fragrance and cosmetic formulations, providing compatible solvency and controlling evaporation. It also finds use in polymer and plastics processing as a processing solvent or intermediate in certain syntheses. Additionally, it is employed in some cleaning and degreasing formulations due to its solvency properties. All use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 531.74
    methanol 286.22
    isopropanol 780.4
    water 0.35
    ethyl acetate 656.73
    n-propanol 685.71
    acetone 693.63
    n-butanol 868.59
    acetonitrile 428.49
    DMF 407.82
    toluene 503.2
    isobutanol 709.37
    1,4-dioxane 1268.49
    methyl acetate 525.45
    THF 2171.9
    2-butanone 738.75
    n-pentanol 552.91
    sec-butanol 935.68
    n-hexane 1367.94
    ethylene glycol 79.66
    NMP 750.99
    cyclohexane 1988.43
    DMSO 490.94
    n-butyl acetate 1393.3
    n-octanol 730.95
    chloroform 3520.09
    n-propyl acetate 569.11
    acetic acid 646.54
    dichloromethane 1913.2
    cyclohexanone 1675.02
    propylene glycol 244.69
    isopropyl acetate 554.27
    DMAc 462.7
    2-ethoxyethanol 413.02
    isopentanol 835.1
    n-heptane 1838.94
    ethyl formate 366.96
    1,2-dichloroethane 1067.28
    n-hexanol 1364.57
    2-methoxyethanol 549.74
    isobutyl acetate 518.06
    tetrachloromethane 909.6
    n-pentyl acetate 692.52
    transcutol 1707.98
    n-heptanol 692.86
    ethylbenzene 405.05
    MIBK 491.77
    2-propoxyethanol 944.52
    tert-butanol 1359.55
    MTBE 1149.72
    2-butoxyethanol 675.89
    propionic acid 623.94
    o-xylene 422.44
    formic acid 88.37
    diethyl ether 800.52
    m-xylene 404.96
    p-xylene 630.54
    chlorobenzene 794.57
    dimethyl carbonate 144.18
    n-octane 497.49
    formamide 89.07
    cyclopentanone 1356.8
    2-pentanone 634.58
    anisole 490.09
    cyclopentyl methyl ether 1257.41
    gamma-butyrolactone 1205.26
    1-methoxy-2-propanol 607.91
    pyridine 923.52
    3-pentanone 561.1
    furfural 937.01
    n-dodecane 272.82
    diethylene glycol 410.68
    diisopropyl ether 482.73
    tert-amyl alcohol 1222.99
    acetylacetone 547.64
    n-hexadecane 305.57
    acetophenone 476.16
    methyl propionate 430.19
    isopentyl acetate 1287.44
    trichloroethylene 2033.22
    n-nonanol 655.39
    cyclohexanol 1507.42
    benzyl alcohol 389.99
    2-ethylhexanol 1296.96
    isooctanol 616.31
    dipropyl ether 1505.94
    1,2-dichlorobenzene 832.08
    ethyl lactate 325.59
    propylene carbonate 908.89
    n-methylformamide 196.75
    2-pentanol 816.7
    n-pentane 785.8
    1-propoxy-2-propanol 1191.39
    1-methoxy-2-propyl acetate 797.25
    2-(2-methoxypropoxy) propanol 656.94
    mesitylene 351.78
    ε-caprolactone 1327.58
    p-cymene 571.36
    epichlorohydrin 1209.11
    1,1,1-trichloroethane 1908.81
    2-aminoethanol 211.87
    morpholine-4-carbaldehyde 720.83
    sulfolane 1352.2
    2,2,4-trimethylpentane 396.72
    2-methyltetrahydrofuran 1910.79
    n-hexyl acetate 1064.41
    isooctane 337.31
    2-(2-butoxyethoxy)ethanol 857.87
    sec-butyl acetate 504.67
    tert-butyl acetate 736.83
    decalin 644.66
    glycerin 251.86
    diglyme 1260.43
    acrylic acid 422.4
    isopropyl myristate 600.33
    n-butyric acid 1111.38
    acetyl acetate 471.33
    di(2-ethylhexyl) phthalate 401.43
    ethyl propionate 508.17
    nitromethane 529.91
    1,2-diethoxyethane 914.13
    benzonitrile 643.86
    trioctyl phosphate 367.68
    1-bromopropane 1200.69
    gamma-valerolactone 1278.39
    n-decanol 515.39
    triethyl phosphate 479.7
    4-methyl-2-pentanol 521.66
    propionitrile 583.46
    vinylene carbonate 659.13
    1,1,2-trichlorotrifluoroethane 1016.38
    DMS 481.93
    cumene 362.49
    2-octanol 574.39
    2-hexanone 671.34
    octyl acetate 652.35
    limonene 1082.79
    1,2-dimethoxyethane 912.15
    ethyl orthosilicate 515.18
    tributyl phosphate 478.77
    diacetone alcohol 677.94
    N,N-dimethylaniline 375.13
    acrylonitrile 461.35
    aniline 528.11
    1,3-propanediol 402.52
    bromobenzene 913.07
    dibromomethane 1785.75
    1,1,2,2-tetrachloroethane 2274.06
    2-methyl-cyclohexyl acetate 919.37
    tetrabutyl urea 531.06
    diisobutyl methanol 875.52
    2-phenylethanol 579.36
    styrene 454.84
    dioctyl adipate 682.47
    dimethyl sulfate 220.59
    ethyl butyrate 996.83
    methyl lactate 255.2
    butyl lactate 591.13
    diethyl carbonate 639.95
    propanediol butyl ether 637.4
    triethyl orthoformate 875.99
    p-tert-butyltoluene 585.57
    methyl 4-tert-butylbenzoate 636.58
    morpholine 1362.78
    tert-butylamine 1270.78
    n-dodecanol 444.47
    dimethoxymethane 331.52
    ethylene carbonate 652.75
    cyrene 467.61
    2-ethoxyethyl acetate 589.18
    2-ethylhexyl acetate 1142.36
    1,2,4-trichlorobenzene 934.25
    4-methylpyridine 885.04
    dibutyl ether 1342.95
    2,6-dimethyl-4-heptanol 875.52
    DEF 586.55
    dimethyl isosorbide 1073.14
    tetrachloroethylene 1482.79
    eugenol 534.1
    triacetin 774.97
    span 80 882.27
    1,4-butanediol 176.57
    1,1-dichloroethane 1442.26
    2-methyl-1-pentanol 574.4
    methyl formate 169.22
    2-methyl-1-butanol 757.54
    n-decane 493.84
    butyronitrile 830.35
    3,7-dimethyl-1-octanol 863.67
    1-chlorooctane 823.1
    1-chlorotetradecane 394.45
    n-nonane 567.24
    undecane 348.08
    tert-butylcyclohexane 599.09
    cyclooctane 726.6
    cyclopentanol 1298.75
    tetrahydropyran 2120.0
    tert-amyl methyl ether 855.65
    2,5,8-trioxanonane 886.2
    1-hexene 1380.84
    2-isopropoxyethanol 418.46
    2,2,2-trifluoroethanol 203.82
    methyl butyrate 684.07

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction