Desoxoglabrolide

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  • Identifiers

    CAS number
    10379-62-1

    Molecular formula
    C30H46O3

    SMILES
    CC1(C2CCC3(C(C2(CCC1O)C)CC=C4C3(CCC5(C4CC6(CC5OC6=O)C)C)C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 83.21%
    Amber 56.24%
    Dry 50.42%
    Cedar 49.5%
    Musk 43.48%
    Sandalwood 38.02%
    Spicy 37.62%
    Balsamic 35.98%
    Camphoreous 34.27%
    Sweet 34.25%

     

    Flavor
    Woody 61.68%
    Camphor 55.51%
    Pine 48.04%
    Earthy 42.49%
    Bitter 39.79%
    Herbal 38.58%
    Balsam 37.61%
    Earth 36.41%
    Spicy 35.65%
    Fresh 31.7%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.9

    pKa est.
    6.64 (neutral)

    Molecular weight
    454.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    209°C

    Melting point expt.

    • 274 - 278 °C

    Flash point

    • 236.38 ˚C est.

  • Synonyms

    • Desoxoglabrolide
    • 10379-62-1
    • 11-hydroxy-2,5,6,10,10,14,21-heptamethyl-23-oxahexacyclo[19.2.1.02,19.05,18.06,15.09,14]tetracos-17-en-22-one
    • 3beta,22beta-Dihydroxyolean-12-en-30-oic acid gamma-lactone
    • CHEBI:172021
    • CHEBI:201463
    • 3b-Hydroxy-12-oleanen-30,22b-olide
    • LS-15288
    • DB-050269
    • (1S,2R,5S,6R,9R,11S,14R,15R,19S,21S)-11-hydroxy-2,5,6,10,10,14,21-heptamethyl-23-oxahexacyclo[19.2.1.0^{2,19.0^{5,18.0^{6,15.0^{9,14]tetracos-17-en-22-one
    • 10379-62-1

  • Applications

    Desoxoglabrolide (CAS 10379-62-1) is used as an odorant or fixative in perfumery and cosmetics; it can serve as a solvent or processing aid in coatings and inks; in the polymers/plastics sector it may act as an intermediate or stabilizer, and in the rubber industry as a processing aid; in cleaning and household products, it can function as a solvent or odor-masking component; in industrial manufacturing, it is commonly evaluated as a processing aid or chemical intermediate.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 12.09
    methanol 7.05
    isopropanol 12.14
    water 0.04
    ethyl acetate 15.19
    n-propanol 19.11
    acetone 16.86
    n-butanol 19.84
    acetonitrile 10.32
    DMF 57.98
    toluene 25.27
    isobutanol 13.7
    1,4-dioxane 44.49
    methyl acetate 12.07
    THF 68.42
    2-butanone 19.8
    n-pentanol 14.98
    sec-butanol 6.47
    n-hexane 0.66
    ethylene glycol 1.94
    NMP 48.19
    cyclohexane 0.9
    DMSO 16.24
    n-butyl acetate 14.41
    n-octanol 8.15
    chloroform 49.71
    n-propyl acetate 11.03
    acetic acid 12.89
    dichloromethane 24.99
    cyclohexanone 32.93
    propylene glycol 3.48
    isopropyl acetate 16.8
    DMAc 49.36
    2-ethoxyethanol 25.0
    isopentanol 15.05
    n-heptane 0.64
    ethyl formate 7.23
    1,2-dichloroethane 14.94
    n-hexanol 17.7
    2-methoxyethanol 31.89
    isobutyl acetate 12.59
    tetrachloromethane 8.25
    n-pentyl acetate 20.17
    transcutol 53.63
    n-heptanol 14.69
    ethylbenzene 9.68
    MIBK 17.69
    2-propoxyethanol 63.58
    tert-butanol 8.48
    MTBE 8.51
    2-butoxyethanol 40.78
    propionic acid 10.91
    o-xylene 11.69
    formic acid 4.99
    diethyl ether 14.6
    m-xylene 17.16
    p-xylene 10.45
    chlorobenzene 21.86
    dimethyl carbonate 15.64
    n-octane 0.27
    formamide 8.08
    cyclopentanone 41.35
    2-pentanone 20.54
    anisole 24.21
    cyclopentyl methyl ether 26.0
    gamma-butyrolactone 36.94
    1-methoxy-2-propanol 38.29
    pyridine 44.63
    3-pentanone 17.66
    furfural 36.81
    n-dodecane 0.18
    diethylene glycol 26.91
    diisopropyl ether 5.23
    tert-amyl alcohol 5.18
    acetylacetone 24.96
    n-hexadecane 0.23
    acetophenone 21.77
    methyl propionate 18.95
    isopentyl acetate 17.85
    trichloroethylene 41.09
    n-nonanol 9.86
    cyclohexanol 10.27
    benzyl alcohol 21.84
    2-ethylhexanol 9.2
    isooctanol 12.13
    dipropyl ether 11.0
    1,2-dichlorobenzene 20.0
    ethyl lactate 10.33
    propylene carbonate 18.42
    n-methylformamide 17.52
    2-pentanol 8.99
    n-pentane 0.79
    1-propoxy-2-propanol 38.4
    1-methoxy-2-propyl acetate 33.76
    2-(2-methoxypropoxy) propanol 25.63
    mesitylene 8.49
    ε-caprolactone 28.91
    p-cymene 6.27
    epichlorohydrin 42.46
    1,1,1-trichloroethane 17.16
    2-aminoethanol 7.54
    morpholine-4-carbaldehyde 72.15
    sulfolane 36.58
    2,2,4-trimethylpentane 0.58
    2-methyltetrahydrofuran 21.52
    n-hexyl acetate 20.5
    isooctane 0.62
    2-(2-butoxyethoxy)ethanol 35.25
    sec-butyl acetate 10.26
    tert-butyl acetate 17.95
    decalin 0.93
    glycerin 8.01
    diglyme 59.02
    acrylic acid 11.25
    isopropyl myristate 7.34
    n-butyric acid 20.7
    acetyl acetate 14.38
    di(2-ethylhexyl) phthalate 12.47
    ethyl propionate 12.47
    nitromethane 23.11
    1,2-diethoxyethane 17.5
    benzonitrile 19.19
    trioctyl phosphate 8.29
    1-bromopropane 9.3
    gamma-valerolactone 74.47
    n-decanol 5.73
    triethyl phosphate 8.97
    4-methyl-2-pentanol 8.3
    propionitrile 14.86
    vinylene carbonate 23.27
    1,1,2-trichlorotrifluoroethane 31.18
    DMS 17.61
    cumene 6.53
    2-octanol 6.86
    2-hexanone 14.59
    octyl acetate 9.91
    limonene 6.09
    1,2-dimethoxyethane 34.91
    ethyl orthosilicate 10.07
    tributyl phosphate 7.05
    diacetone alcohol 20.36
    N,N-dimethylaniline 17.92
    acrylonitrile 18.09
    aniline 25.56
    1,3-propanediol 15.52
    bromobenzene 22.41
    dibromomethane 17.33
    1,1,2,2-tetrachloroethane 31.29
    2-methyl-cyclohexyl acetate 15.25
    tetrabutyl urea 10.85
    diisobutyl methanol 5.78
    2-phenylethanol 28.97
    styrene 11.02
    dioctyl adipate 12.69
    dimethyl sulfate 20.51
    ethyl butyrate 12.25
    methyl lactate 15.45
    butyl lactate 19.75
    diethyl carbonate 8.36
    propanediol butyl ether 24.14
    triethyl orthoformate 13.88
    p-tert-butyltoluene 6.59
    methyl 4-tert-butylbenzoate 30.52
    morpholine 53.11
    tert-butylamine 5.34
    n-dodecanol 3.24
    dimethoxymethane 51.43
    ethylene carbonate 18.37
    cyrene 30.4
    2-ethoxyethyl acetate 31.34
    2-ethylhexyl acetate 13.95
    1,2,4-trichlorobenzene 26.75
    4-methylpyridine 39.44
    dibutyl ether 5.37
    2,6-dimethyl-4-heptanol 5.78
    DEF 22.99
    dimethyl isosorbide 43.55
    tetrachloroethylene 22.87
    eugenol 33.71
    triacetin 23.43
    span 80 21.64
    1,4-butanediol 6.49
    1,1-dichloroethane 15.09
    2-methyl-1-pentanol 10.94
    methyl formate 10.5
    2-methyl-1-butanol 11.97
    n-decane 0.48
    butyronitrile 14.36
    3,7-dimethyl-1-octanol 7.54
    1-chlorooctane 3.01
    1-chlorotetradecane 0.83
    n-nonane 0.37
    undecane 0.27
    tert-butylcyclohexane 0.88
    cyclooctane 0.51
    cyclopentanol 11.45
    tetrahydropyran 27.93
    tert-amyl methyl ether 6.86
    2,5,8-trioxanonane 36.58
    1-hexene 3.1
    2-isopropoxyethanol 19.54
    2,2,2-trifluoroethanol 7.32
    methyl butyrate 13.18

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction