Deoxyribose

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  • Identifiers

    CAS number
    533-67-5

    Molecular formula
    C5H10O4

    SMILES
    C1[C@@H]([C@H](OC1O)CO)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 56.07%
    Sweet 42.75%
    Alcoholic 27.24%
    Fruity 26.01%
    Caramellic 24.5%
    Buttery 22.68%
    Milky 21.65%
    Creamy 20.5%
    Dairy 18.21%
    Ethereal 18.18%

     

    Flavor
    Sweet 75.46%
    Odorless 54.45%
    Bitter 45.16%
    Sweet-like 30.25%
    Fatty 24.95%
    Cauliflower 24.59%
    Caramel 24.2%
    Very slight 23.29%
    Alcoholic 22.01%
    Alkaline 21.71%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.0

    pKa est.
    6.67 (neutral)

    Molecular weight
    134.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    372°C

    Flash point

    • 161.55 ˚C est.

  • Synonyms

    • 2 Deoxyribose
    • RefChem:403486
    • GlyTouCan:G10911CG
    • G10911CG
    • (2S,4R,5S)-5-(hydroxymethyl)oxolane-2,4-diol
    • 533-67-5
    • D-erythro-Pentose, 2-deoxy-
    • Deoxyribose
    • (4S,5R)-5-(hydroxymethyl)oxolane-2,4-diol
    • 2-deoxy-d-ribofuranose
    • 1831121-84-6
    • (4S,5R)-5-(hydroxymethyl)tetrahydrofuran-2,4-diol
    • Cladribine EP impurity E
    • 2-desoxyribose
    • SCHEMBL36812
    • SCHEMBL3719486
    • SCHEMBL6330159
    • 2-Deoxy-D-erythro-pentofuranose
    • CHEBI:90761
    • GLXC-19342
    • Ribofuranose, 2-deoxy- [-H2O]
    • MFCD00075746
    • AKOS006271845
    • AC-6194
    • AT39710
    • SY141355
    • (4S,5R)-5-methyloltetrahydrofuran-2,4-diol
    • C01801
    • EN300-104560
    • 533D675
    • Q27162723
    • 28EE252E-18BB-427B-87DE-25EEA2FA6E02
    • 533-67-5

  • Applications

    Deoxyribose (CAS 533-67-5) is primarily used as a building block in nucleotide chemistry, serving as a starting material for the synthesis of deoxyribonucleosides and nucleotide derivatives for pharmaceutical and biotech workflows. In nucleic acid synthesis and molecular biology, it provides a sugar scaffold for oligonucleotide synthesis. In biochemical research and enzymology, it is used as a substrate in enzymatic reactions and as a reference standard in carbohydrate analysis. In specialty chemical manufacturing, it is a precursor for nucleoside analogs and related intermediates.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 115.51
    methanol 371.95
    isopropanol 59.99
    water 2006.99
    ethyl acetate 20.82
    n-propanol 58.55
    acetone 72.48
    n-butanol 41.27
    acetonitrile 35.38
    DMF 1192.29
    toluene 1.76
    isobutanol 35.41
    1,4-dioxane 79.93
    methyl acetate 18.54
    THF 146.49
    2-butanone 23.56
    n-pentanol 21.42
    sec-butanol 32.47
    n-hexane 0.56
    ethylene glycol 738.25
    NMP 459.58
    cyclohexane 1.18
    DMSO 1454.29
    n-butyl acetate 8.05
    n-octanol 14.43
    chloroform 10.51
    n-propyl acetate 11.07
    acetic acid 349.16
    dichloromethane 14.21
    cyclohexanone 44.08
    propylene glycol 312.73
    isopropyl acetate 15.53
    DMAc 428.77
    2-ethoxyethanol 212.05
    isopentanol 31.0
    n-heptane 1.61
    ethyl formate 38.45
    1,2-dichloroethane 12.02
    n-hexanol 21.22
    2-methoxyethanol 499.37
    isobutyl acetate 6.07
    tetrachloromethane 5.29
    n-pentyl acetate 8.08
    transcutol 133.37
    n-heptanol 17.34
    ethylbenzene 1.33
    MIBK 25.07
    2-propoxyethanol 119.67
    tert-butanol 74.82
    MTBE 12.0
    2-butoxyethanol 63.35
    propionic acid 98.2
    o-xylene 3.32
    formic acid 1531.02
    diethyl ether 10.04
    m-xylene 4.17
    p-xylene 1.9
    chlorobenzene 2.99
    dimethyl carbonate 32.2
    n-octane 0.79
    formamide 1023.38
    cyclopentanone 102.04
    2-pentanone 29.62
    anisole 9.42
    cyclopentyl methyl ether 31.24
    gamma-butyrolactone 155.26
    1-methoxy-2-propanol 283.91
    pyridine 17.06
    3-pentanone 16.11
    furfural 157.75
    n-dodecane 0.67
    diethylene glycol 288.28
    diisopropyl ether 4.53
    tert-amyl alcohol 41.77
    acetylacetone 59.03
    n-hexadecane 0.72
    acetophenone 16.65
    methyl propionate 30.67
    isopentyl acetate 7.94
    trichloroethylene 18.47
    n-nonanol 12.55
    cyclohexanol 29.41
    benzyl alcohol 21.29
    2-ethylhexanol 9.9
    isooctanol 13.72
    dipropyl ether 9.53
    1,2-dichlorobenzene 4.9
    ethyl lactate 34.93
    propylene carbonate 52.71
    n-methylformamide 532.61
    2-pentanol 21.17
    n-pentane 0.85
    1-propoxy-2-propanol 59.86
    1-methoxy-2-propyl acetate 26.71
    2-(2-methoxypropoxy) propanol 51.78
    mesitylene 4.12
    ε-caprolactone 45.34
    p-cymene 3.47
    epichlorohydrin 87.23
    1,1,1-trichloroethane 7.18
    2-aminoethanol 513.75
    morpholine-4-carbaldehyde 367.44
    sulfolane 291.72
    2,2,4-trimethylpentane 0.87
    2-methyltetrahydrofuran 41.53
    n-hexyl acetate 11.76
    isooctane 0.85
    2-(2-butoxyethoxy)ethanol 67.36
    sec-butyl acetate 6.93
    tert-butyl acetate 19.62
    decalin 0.73
    glycerin 757.35
    diglyme 126.01
    acrylic acid 151.16
    isopropyl myristate 5.59
    n-butyric acid 73.87
    acetyl acetate 16.97
    di(2-ethylhexyl) phthalate 11.08
    ethyl propionate 12.44
    nitromethane 370.8
    1,2-diethoxyethane 13.37
    benzonitrile 11.9
    trioctyl phosphate 9.91
    1-bromopropane 3.01
    gamma-valerolactone 190.78
    n-decanol 9.09
    triethyl phosphate 10.31
    4-methyl-2-pentanol 16.56
    propionitrile 16.42
    vinylene carbonate 47.01
    1,1,2-trichlorotrifluoroethane 204.06
    DMS 13.11
    cumene 1.99
    2-octanol 8.8
    2-hexanone 11.76
    octyl acetate 8.19
    limonene 5.14
    1,2-dimethoxyethane 143.18
    ethyl orthosilicate 8.82
    tributyl phosphate 8.52
    diacetone alcohol 73.54
    N,N-dimethylaniline 11.88
    acrylonitrile 37.69
    aniline 10.46
    1,3-propanediol 341.2
    bromobenzene 1.93
    dibromomethane 6.44
    1,1,2,2-tetrachloroethane 19.01
    2-methyl-cyclohexyl acetate 10.49
    tetrabutyl urea 15.61
    diisobutyl methanol 8.67
    2-phenylethanol 17.53
    styrene 1.4
    dioctyl adipate 11.2
    dimethyl sulfate 105.05
    ethyl butyrate 10.51
    methyl lactate 101.9
    butyl lactate 19.29
    diethyl carbonate 7.03
    propanediol butyl ether 63.76
    triethyl orthoformate 9.97
    p-tert-butyltoluene 3.65
    methyl 4-tert-butylbenzoate 30.31
    morpholine 120.1
    tert-butylamine 21.1
    n-dodecanol 6.76
    dimethoxymethane 180.67
    ethylene carbonate 33.18
    cyrene 95.82
    2-ethoxyethyl acetate 14.29
    2-ethylhexyl acetate 5.44
    1,2,4-trichlorobenzene 6.01
    4-methylpyridine 15.64
    dibutyl ether 5.18
    2,6-dimethyl-4-heptanol 8.67
    DEF 84.56
    dimethyl isosorbide 76.06
    tetrachloroethylene 16.95
    eugenol 42.28
    triacetin 21.65
    span 80 43.13
    1,4-butanediol 151.75
    1,1-dichloroethane 6.29
    2-methyl-1-pentanol 16.61
    methyl formate 272.35
    2-methyl-1-butanol 27.99
    n-decane 1.03
    butyronitrile 15.93
    3,7-dimethyl-1-octanol 12.46
    1-chlorooctane 3.42
    1-chlorotetradecane 1.55
    n-nonane 0.97
    undecane 0.8
    tert-butylcyclohexane 0.75
    cyclooctane 0.83
    cyclopentanol 59.79
    tetrahydropyran 20.7
    tert-amyl methyl ether 12.21
    2,5,8-trioxanonane 101.61
    1-hexene 1.3
    2-isopropoxyethanol 83.72
    2,2,2-trifluoroethanol 295.48
    methyl butyrate 19.81

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction