Decarboxy carnosine hydrochloride

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  • Identifiers

    CAS number
    57022-38-5

    Molecular formula
    C8H16Cl2N4O

    SMILES
    C1=C(NC=N1)CCNC(=O)CCN.Cl.Cl

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 55.85%
    Fishy 45.97%
    Meaty 43.56%
    Savory 39.99%
    Cheesy 28.15%
    Cooked 25.55%
    Cooling 24.3%
    Roasted 24.02%
    Ripe 23.39%
    Animal 20.7%

     

    Flavor
    Odorless 52.59%
    Bitter 47.96%
    Mild 29.58%
    Bland 27.79%
    Roasted 26.12%
    Sweet-like 22.12%
    Cooked 21.27%
    Yeast 20.59%
    Faint 20.41%
    Nitrile 20.13%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    6.36 (neutral)

    Molecular weight
    255.14 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    418°C

    Flash point

    • 224.71 ˚C est.

  • Synonyms

    • 57022-38-5
    • Carcinine dihydrochloride
    • Decarboxy carnosine hydrochloride
    • Decarboxy carnosine HCl
    • Carcinine (2HCl)
    • beta-Alanylhistamine dihydrochloride
    • UNII-6X7K9I5QR7
    • 6X7K9I5QR7
    • DTXSID00205634
    • .BETA.-ALANYLHISTAMINE DIHYDROCHLORIDE
    • RefChem:131240
    • DTXCID30128125
    • DECARBOXY CARNOSINE HCL [INCI]
    • N-(2-(1H-Imidazol-5-yl)ethyl)-3-aminopropanamide dihydrochloride
    • Alistin
    • 3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide;dihydrochloride
    • Propanamide, 3-amino-N-2-(1H-imidazol-4-yl)ethyl-, dihydrochloride
    • 3-amino-N-[2-(1H-imidazol-5-yl)ethyl]propanamide dihydrochloride
    • Propanamide, 3-amino-N-(2-(1H-imidazol-4-yl)ethyl)-, dihydrochloride
    • Propanamide, 3-amino-N-(2-(1H-imidazol-5-yl)ethyl)-, hydrochloride (1:2)
    • Carcinine; beta-Alanylhistamine
    • Carcinine hydrochloride salt
    • Prestwick_701
    • Carcinine (dihydrochloride)
    • Carcinine; -Alanylhistamine
    • orb2664594
    • CHEMBL1255583
    • SCHEMBL20528864
    • |A-Alanylhistamine dihydrochloride
    • ZQTUNIWBUQUKAM-UHFFFAOYSA-N
    • Carcinine dihydrochloride [WHO-DD]
    • HCA02238
    • MFCD22200567
    • AKOS025401659
    • HY-107567B
    • NCGC00093682-01
    • AC-24160
    • AS-87462
    • Carcinine dihydrochloride, >=98% (HPLC)
    • DB-361028
    • EU-0100210
    • C 2321
    • C16004
    • SR-01000075747
    • SR-01000075747-1
    • Q27265660
    • N-(2-(1H-IMIDAZOL-5-YL)ETHYL)-3-AMINOPROPANAMIDE 2HCL
    • N-(2-(1H-Imidazol-5-yl)ethyl)-3-aminopropanamidedihydrochloride
    • N-[2-(1H-Imidazol-5-yl)ethyl]-beta-alaninamide--hydrogen chloride (1/2)
    • 57022-38-5

  • Applications

    Decarboxy carnosine hydrochloride (CAS 57022-38-5) is typically encountered as a peptide-related intermediate and formulation additive; it may be used as an intermediate in peptide or pharmaceutical synthesis and as a stabilizer or antioxidant in cosmetic and personal care products; it can function as a chelating and stabilizing agent in cleaning formulations and industrial processes; in polymers and coatings, it may act as a processing aid or stabilizer; and it is occasionally evaluated for use in coatings or inks to improve formulation performance, depending on regulatory and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 79.05
    methanol 348.72
    isopropanol 23.65
    water 1081.9
    ethyl acetate 7.94
    n-propanol 38.24
    acetone 25.77
    n-butanol 20.41
    acetonitrile 13.56
    DMF 999.95
    toluene 1.01
    isobutanol 20.17
    1,4-dioxane 9.32
    methyl acetate 10.64
    THF 33.17
    2-butanone 14.48
    n-pentanol 12.93
    sec-butanol 14.23
    n-hexane 0.21
    ethylene glycol 308.82
    NMP 472.58
    cyclohexane 0.19
    DMSO 505.23
    n-butyl acetate 4.39
    n-octanol 1.87
    chloroform 6.05
    n-propyl acetate 5.01
    acetic acid 549.08
    dichloromethane 6.86
    cyclohexanone 27.38
    propylene glycol 293.32
    isopropyl acetate 4.12
    DMAc 549.24
    2-ethoxyethanol 103.73
    isopentanol 12.18
    n-heptane 0.18
    ethyl formate 26.02
    1,2-dichloroethane 4.13
    n-hexanol 5.72
    2-methoxyethanol 299.96
    isobutyl acetate 3.44
    tetrachloromethane 1.47
    n-pentyl acetate 2.89
    transcutol 77.1
    n-heptanol 3.26
    ethylbenzene 0.48
    MIBK 5.03
    2-propoxyethanol 46.8
    tert-butanol 13.64
    MTBE 2.43
    2-butoxyethanol 22.59
    propionic acid 117.57
    o-xylene 1.32
    formic acid 1507.47
    diethyl ether 2.15
    m-xylene 1.34
    p-xylene 0.99
    chlorobenzene 1.98
    dimethyl carbonate 15.42
    n-octane 0.08
    formamide 1095.06
    cyclopentanone 61.23
    2-pentanone 9.25
    anisole 2.36
    cyclopentyl methyl ether 7.95
    gamma-butyrolactone 110.47
    1-methoxy-2-propanol 115.39
    pyridine 15.61
    3-pentanone 7.67
    furfural 122.87
    n-dodecane 0.06
    diethylene glycol 113.0
    diisopropyl ether 0.61
    tert-amyl alcohol 11.42
    acetylacetone 15.09
    n-hexadecane 0.07
    acetophenone 6.36
    methyl propionate 17.96
    isopentyl acetate 3.96
    trichloroethylene 11.83
    n-nonanol 1.83
    cyclohexanol 9.48
    benzyl alcohol 12.37
    2-ethylhexanol 2.23
    isooctanol 2.53
    dipropyl ether 1.74
    1,2-dichlorobenzene 2.32
    ethyl lactate 16.51
    propylene carbonate 40.19
    n-methylformamide 447.75
    2-pentanol 6.13
    n-pentane 0.2
    1-propoxy-2-propanol 19.06
    1-methoxy-2-propyl acetate 10.94
    2-(2-methoxypropoxy) propanol 20.36
    mesitylene 0.9
    ε-caprolactone 29.27
    p-cymene 0.79
    epichlorohydrin 39.31
    1,1,1-trichloroethane 2.37
    2-aminoethanol 328.5
    morpholine-4-carbaldehyde 200.33
    sulfolane 168.72
    2,2,4-trimethylpentane 0.17
    2-methyltetrahydrofuran 10.53
    n-hexyl acetate 3.36
    isooctane 0.09
    2-(2-butoxyethoxy)ethanol 26.04
    sec-butyl acetate 2.54
    tert-butyl acetate 3.87
    decalin 0.14
    glycerin 536.13
    diglyme 42.14
    acrylic acid 192.93
    isopropyl myristate 1.06
    n-butyric acid 75.02
    acetyl acetate 7.1
    di(2-ethylhexyl) phthalate 5.72
    ethyl propionate 4.18
    nitromethane 385.33
    1,2-diethoxyethane 4.14
    benzonitrile 7.86
    trioctyl phosphate 2.87
    1-bromopropane 1.41
    gamma-valerolactone 136.35
    n-decanol 1.28
    triethyl phosphate 3.66
    4-methyl-2-pentanol 3.2
    propionitrile 9.19
    vinylene carbonate 38.85
    1,1,2-trichlorotrifluoroethane 142.55
    DMS 6.86
    cumene 0.56
    2-octanol 1.45
    2-hexanone 4.75
    octyl acetate 1.95
    limonene 1.06
    1,2-dimethoxyethane 38.64
    ethyl orthosilicate 3.17
    tributyl phosphate 3.5
    diacetone alcohol 18.42
    N,N-dimethylaniline 3.21
    acrylonitrile 25.41
    aniline 7.82
    1,3-propanediol 191.42
    bromobenzene 1.19
    dibromomethane 2.77
    1,1,2,2-tetrachloroethane 8.81
    2-methyl-cyclohexyl acetate 3.84
    tetrabutyl urea 6.02
    diisobutyl methanol 1.26
    2-phenylethanol 6.89
    styrene 0.59
    dioctyl adipate 3.3
    dimethyl sulfate 53.61
    ethyl butyrate 3.74
    methyl lactate 65.21
    butyl lactate 11.22
    diethyl carbonate 3.07
    propanediol butyl ether 34.82
    triethyl orthoformate 3.76
    p-tert-butyltoluene 0.72
    methyl 4-tert-butylbenzoate 9.91
    morpholine 31.08
    tert-butylamine 3.43
    n-dodecanol 0.93
    dimethoxymethane 47.53
    ethylene carbonate 25.56
    cyrene 45.57
    2-ethoxyethyl acetate 6.39
    2-ethylhexyl acetate 2.77
    1,2,4-trichlorobenzene 3.89
    4-methylpyridine 11.04
    dibutyl ether 0.92
    2,6-dimethyl-4-heptanol 1.26
    DEF 42.46
    dimethyl isosorbide 25.22
    tetrachloroethylene 7.31
    eugenol 16.5
    triacetin 9.57
    span 80 18.14
    1,4-butanediol 92.49
    1,1-dichloroethane 2.61
    2-methyl-1-pentanol 8.79
    methyl formate 181.06
    2-methyl-1-butanol 14.16
    n-decane 0.09
    butyronitrile 8.43
    3,7-dimethyl-1-octanol 1.99
    1-chlorooctane 0.37
    1-chlorotetradecane 0.18
    n-nonane 0.09
    undecane 0.07
    tert-butylcyclohexane 0.12
    cyclooctane 0.09
    cyclopentanol 25.13
    tetrahydropyran 4.68
    tert-amyl methyl ether 2.69
    2,5,8-trioxanonane 29.92
    1-hexene 0.73
    2-isopropoxyethanol 31.47
    2,2,2-trifluoroethanol 252.69
    methyl butyrate 8.57

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction