Decamethylcyclopentasiloxane

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  • Identifiers

    CAS number
    541-02-6

    Molecular formula
    C10H30O5Si5

    SMILES
    C[Si]1(O[Si](O[Si](O[Si](O[Si](O1)(C)C)(C)C)(C)C)(C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Odorless 64.86%
    Fruity 20.97%
    Green 18.79%
    Fresh 16.84%
    Ethereal 15.95%
    Alcoholic 15.58%
    Cooling 14.33%
    Earthy 13.86%
    Creamy 13.65%
    Meaty 13.62%

     

    Flavor
    Green 55.7%
    Earthy 50.4%
    Vegetable 39.74%
    Sulfurous 26.54%
    Sweet 25.16%
    Blackberry 24.66%
    Burnt 24.51%
    Potato 21.91%
    Herbal 21.62%
    Musty 20.9%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    3.76 (weak acid)

    Molecular weight
    370.77 g/mol

    Melting point expt.

    • -38 °C

    Boiling point

    • 210 °C

    Flash point

    • 91.38 ˚C est.
    • 73 °C (163 °F) - closed cup

    Solubility expt.

    • In water, 1.7X10-2 mg/L at 25 °C

  • Synonyms

    • DECAMETHYLCYCLOPENTASILOXANE
    • 541-02-6
    • Cyclomethicone 5
    • Dimethylsiloxane pentamer
    • Dow corning 345
    • Cyclic dimethylsiloxane pentamer
    • NUC silicone VS 7158
    • Silicon SF 1202
    • Ciclopentasiloxane
    • Cyclomethicone D5
    • Dekamethylcyklopentasiloxan
    • D5-sil
    • KF 995
    • VS 7158
    • 0THT5PCI0R
    • SF 1202
    • DTXSID1027184
    • JEESILC CPS-211
    • XIAMETER PMX-0245
    • DTXCID907184
    • Cyclopentasiloxane, 2,2,4,4,6,6,8,8,10,10-decamethyl-
    • KF-995
    • DOW CORNING ST CYCLOMETHICONE 5
    • Lightening Serum
    • RefChem:54914
    • Smooth and Soft Cuticles
    • 3CE PINK IM GOOD MASCARA
    • AuQuest Smooth and Soft Cuticles
    • 208-764-9
    • Cyclopentasiloxane, decamethyl-
    • 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
    • CYCLOPENTASILOXANE
    • Ddecamethylcyclopentasiloxane
    • Botanisil CP 33
    • C10H30O5Si5
    • MFCD00046966
    • 2,2,4,4,6,6,8,8,10,10-Decamethylcyclopentasiloxane
    • decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
    • 2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecane
    • CCRIS 1328
    • HSDB 5683
    • Dekamethylcyklopentasiloxan [Czech]
    • EINECS 208-764-9
    • UNII-0THT5PCI0R
    • decamethyl cyclopentasiloxane
    • BRN 1800166
    • D5 Cyclomethicone
    • Polysiloxane D5 CRS
    • D5
    • Simethicone Impurity 4
    • dimethylcyclopentasiloxane
    • Decamethylcylopentasiloxane
    • EC 208-764-9
    • SCHEMBL28497
    • N-Propylheptamethyltrisiloxane
    • 4-04-00-04128 (Beilstein Handbook Reference)
    • orb2279217
    • CYCLOPENTASILOXANE (D5)
    • CHEMBL1885178
    • 1403 Dimethicone & Dimethiconol
    • CHEBI:191092
    • Decamethylcyclopentasiloxane, 97%
    • CYCLOMETHICONE 5 [USP-RS]
    • CYCLOMETHICONE 5 [WHO-DD]
    • Decamethylcyclopentasiloxane (NIST)
    • Tox21_303170
    • CD3770
    • CYCLOPENTASILOXANE, DECAMETHYL
    • AKOS008901199
    • CS-W009767
    • DB11244
    • FD20850
    • HY-W009051
    • DECAMETHYLCYCLOPENTASILOXANE [MI]
    • s25375
    • MSK002145-1000M
    • NCGC00163981-01
    • NCGC00257224-01
    • OCTAMETHYLCYCLOTETRASILOXANE (D5)
    • AS-59731
    • CAS-541-02-6
    • DA-72620
    • DECAMETHYLCYCLOPENTASILOXANE [HSDB]
    • SY048230
    • KP-545 COMPONENT CYCLOMETHICONE 5
    • D1890
    • D3770
    • Decamethylcyclopentasiloxane (cyclic monomer)
    • NS00043162
    • D78203
    • S05475
    • Decamethylcyclopentasiloxane, analytical standard
    • Q414350
    • Decamethylcyclopentasiloxane Solution in Methanol, 1000ug/mL
    • Cyclomethicone 5, United States Pharmacopeia (USP) Reference Standard
    • 2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane #
    • D5 Cyclomethicone, Pharmaceutical Secondary Standard; Certified Reference Material
    • 541-02-6

  • Applications

    Decamethylcyclopentasiloxane (CAS 541-02-6) is a volatile cyclic siloxane widely used as a solvent and carrier in fragrance and cosmetics, helping dissolve and disperse volatile aroma components and providing a light, non-greasy feel. It is commonly employed as a solvent and processing aid in cosmetics and personal care products, including hair and skin care, where it can improve spreadability and fast evaporation. In household products and cleaning formulations, it serves as a volatile solvent for fragrance oils and active ingredients, aiding formulation stability and sensory characteristics. It also functions as a processing aid or slip agent in polymer and coating formulations, including inks and silicone-modified materials. In industrial and electronics cleaning contexts, it may be used as a specialty solvent for precision cleaning, within formulation limits and regulatory requirements. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 151.25
    methanol 189.68
    isopropanol 114.1
    water 28.32
    ethyl acetate 198.99
    n-propanol 131.81
    acetone 297.19
    n-butanol 115.38
    acetonitrile 122.3
    DMF 581.12
    toluene 138.67
    isobutanol 88.03
    1,4-dioxane 363.79
    methyl acetate 187.78
    THF 790.32
    2-butanone 196.8
    n-pentanol 84.33
    sec-butanol 102.09
    n-hexane 31.86
    ethylene glycol 89.94
    NMP 777.28
    cyclohexane 65.09
    DMSO 459.59
    n-butyl acetate 145.05
    n-octanol 93.12
    chloroform 359.79
    n-propyl acetate 140.03
    acetic acid 221.51
    dichloromethane 327.54
    cyclohexanone 390.15
    propylene glycol 122.01
    isopropyl acetate 158.85
    DMAc 471.42
    2-ethoxyethanol 165.39
    isopentanol 76.51
    n-heptane 36.83
    ethyl formate 171.36
    1,2-dichloroethane 204.01
    n-hexanol 121.97
    2-methoxyethanol 318.15
    isobutyl acetate 98.33
    tetrachloromethane 86.59
    n-pentyl acetate 161.41
    transcutol 248.25
    n-heptanol 92.89
    ethylbenzene 62.83
    MIBK 127.35
    2-propoxyethanol 257.94
    tert-butanol 113.68
    MTBE 93.52
    2-butoxyethanol 160.28
    propionic acid 179.14
    o-xylene 92.64
    formic acid 136.62
    diethyl ether 148.9
    m-xylene 103.06
    p-xylene 77.15
    chlorobenzene 170.3
    dimethyl carbonate 188.8
    n-octane 20.39
    formamide 219.85
    cyclopentanone 604.73
    2-pentanone 199.76
    anisole 140.52
    cyclopentyl methyl ether 298.99
    gamma-butyrolactone 733.33
    1-methoxy-2-propanol 299.44
    pyridine 288.85
    3-pentanone 166.17
    furfural 534.83
    n-dodecane 16.31
    diethylene glycol 208.42
    diisopropyl ether 62.8
    tert-amyl alcohol 95.48
    acetylacetone 309.55
    n-hexadecane 18.39
    acetophenone 159.35
    methyl propionate 215.85
    isopentyl acetate 112.27
    trichloroethylene 354.4
    n-nonanol 92.28
    cyclohexanol 156.59
    benzyl alcohol 118.42
    2-ethylhexanol 76.61
    isooctanol 67.04
    dipropyl ether 122.9
    1,2-dichlorobenzene 167.31
    ethyl lactate 119.89
    propylene carbonate 401.26
    n-methylformamide 293.25
    2-pentanol 88.94
    n-pentane 39.03
    1-propoxy-2-propanol 191.49
    1-methoxy-2-propyl acetate 230.71
    2-(2-methoxypropoxy) propanol 139.61
    mesitylene 69.53
    ε-caprolactone 354.04
    p-cymene 54.56
    epichlorohydrin 448.35
    1,1,1-trichloroethane 183.87
    2-aminoethanol 128.64
    morpholine-4-carbaldehyde 595.43
    sulfolane 800.59
    2,2,4-trimethylpentane 15.85
    2-methyltetrahydrofuran 342.86
    n-hexyl acetate 190.38
    isooctane 13.27
    2-(2-butoxyethoxy)ethanol 193.56
    sec-butyl acetate 104.86
    tert-butyl acetate 172.39
    decalin 28.75
    glycerin 212.19
    diglyme 266.03
    acrylic acid 194.62
    isopropyl myristate 94.39
    n-butyric acid 197.29
    acetyl acetate 193.31
    di(2-ethylhexyl) phthalate 95.77
    ethyl propionate 141.53
    nitromethane 407.7
    1,2-diethoxyethane 134.74
    benzonitrile 133.9
    trioctyl phosphate 81.11
    1-bromopropane 122.94
    gamma-valerolactone 709.52
    n-decanol 71.66
    triethyl phosphate 86.27
    4-methyl-2-pentanol 56.0
    propionitrile 101.12
    vinylene carbonate 344.93
    1,1,2-trichlorotrifluoroethane 352.3
    DMS 198.56
    cumene 45.57
    2-octanol 75.5
    2-hexanone 129.08
    octyl acetate 120.27
    limonene 78.67
    1,2-dimethoxyethane 246.0
    ethyl orthosilicate 77.98
    tributyl phosphate 84.57
    diacetone alcohol 177.45
    N,N-dimethylaniline 114.4
    acrylonitrile 137.25
    aniline 161.83
    1,3-propanediol 147.72
    bromobenzene 169.84
    dibromomethane 209.92
    1,1,2,2-tetrachloroethane 319.49
    2-methyl-cyclohexyl acetate 133.62
    tetrabutyl urea 127.65
    diisobutyl methanol 48.97
    2-phenylethanol 145.87
    styrene 78.47
    dioctyl adipate 128.51
    dimethyl sulfate 327.99
    ethyl butyrate 133.66
    methyl lactate 206.55
    butyl lactate 154.9
    diethyl carbonate 96.61
    propanediol butyl ether 153.63
    triethyl orthoformate 109.75
    p-tert-butyltoluene 61.71
    methyl 4-tert-butylbenzoate 188.28
    morpholine 384.75
    tert-butylamine 79.74
    n-dodecanol 57.09
    dimethoxymethane 405.21
    ethylene carbonate 285.68
    cyrene 236.0
    2-ethoxyethyl acetate 201.23
    2-ethylhexyl acetate 103.86
    1,2,4-trichlorobenzene 208.79
    4-methylpyridine 248.58
    dibutyl ether 88.7
    2,6-dimethyl-4-heptanol 48.97
    DEF 252.94
    dimethyl isosorbide 314.63
    tetrachloroethylene 196.0
    eugenol 194.08
    triacetin 210.6
    span 80 182.61
    1,4-butanediol 67.53
    1,1-dichloroethane 171.41
    2-methyl-1-pentanol 62.06
    methyl formate 259.24
    2-methyl-1-butanol 79.64
    n-decane 26.16
    butyronitrile 103.77
    3,7-dimethyl-1-octanol 69.88
    1-chlorooctane 70.25
    1-chlorotetradecane 35.75
    n-nonane 24.89
    undecane 19.98
    tert-butylcyclohexane 23.91
    cyclooctane 31.89
    cyclopentanol 230.19
    tetrahydropyran 302.73
    tert-amyl methyl ether 99.62
    2,5,8-trioxanonane 217.72
    1-hexene 60.22
    2-isopropoxyethanol 112.9
    2,2,2-trifluoroethanol 139.2
    methyl butyrate 166.62

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction