d-Glucose, ether with glycerol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    100402-60-6

    Molecular formula
    C15H30O14

    SMILES
    C([C@H]([C@H]([C@@H]([C@H](C=O)O[C@@H](C=O)[C@H]([C@@H]([C@@H](CO)O)O)O)O)O)O)O.C(C(CO)O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 68.72%
    Sweet 42.34%
    Savory 20.62%
    Buttery 20.58%
    Caramellic 20.39%
    Alcoholic 17.19%
    Milky 16.32%
    Clean 15.78%
    Bitter 15.76%
    Cooling 14.9%

     

    Flavor
    Odorless 62.28%
    Sweet 32.51%
    Sweet-like 30.67%
    Very mild 27.91%
    Bitter 24.72%
    Bland 24.09%
    Very slight 20.23%
    Mild 19.69%
    Yeast 19.66%
    Acetoin 18.56%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    3.26 (weak acid)

    Molecular weight
    434.39 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    2590°C

    Flash point

    • 311.79 ˚C est.

  • Synonyms

    • d-Glucose, ether with glycerol
    • EINECS 309-496-6
    • EC 309-496-6
    • 100402-60-6
    • DTXSID10143255
    • RefChem:130608
    • DTXCID3065746
    • 309-496-6
    • (2R,2'R,3S,3'S,4R,4'R,5R,5'R)-2,2'-Oxybis(3,4,5,6-tetrahydroxyhexanal)--propane-1,2,3-triol (1/1)
    • 100402-60-6

  • Applications

    D-Glucose, ether with glycerol, a glyceryl glucoside, is a sugar-derived compound where glucose is linked to glycerol by an ether bond. It is commonly used as a humectant and skin-conditioning agent in cosmetic and personal care formulations. It is also considered an intermediate in carbohydrate chemistry for the synthesis of glycoside derivatives and related glyceryl compounds; in consumer applications, it may serve as a solvent or co-solvent in cleaning and household formulations; industrially, it can function as a biobased polyol derivative suitable for polymer formulations and coatings; it may be used as an excipient or formulation aid in certain pharmaceutical products, subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.79
    methanol 4.38
    isopropanol 0.28
    water 326.43
    ethyl acetate 0.12
    n-propanol 0.57
    acetone 0.29
    n-butanol 0.33
    acetonitrile 0.21
    DMF 51.17
    toluene 0.07
    isobutanol 0.23
    1,4-dioxane 0.82
    methyl acetate 0.19
    THF 0.71
    2-butanone 0.27
    n-pentanol 0.14
    sec-butanol 0.32
    n-hexane 0.02
    ethylene glycol 25.92
    NMP 51.05
    cyclohexane 0.16
    DMSO 179.47
    n-butyl acetate 0.09
    n-octanol 0.2
    chloroform 0.04
    n-propyl acetate 0.06
    acetic acid 4.89
    dichloromethane 0.06
    cyclohexanone 0.8
    propylene glycol 11.0
    isopropyl acetate 0.08
    DMAc 29.88
    2-ethoxyethanol 2.78
    isopentanol 0.17
    n-heptane 0.1
    ethyl formate 0.25
    1,2-dichloroethane 0.1
    n-hexanol 0.23
    2-methoxyethanol 11.21
    isobutyl acetate 0.03
    tetrachloromethane 0.03
    n-pentyl acetate 0.1
    transcutol 4.11
    n-heptanol 0.27
    ethylbenzene 0.04
    MIBK 0.11
    2-propoxyethanol 2.03
    tert-butanol 0.3
    MTBE 0.08
    2-butoxyethanol 1.26
    propionic acid 1.6
    o-xylene 0.14
    formic acid 83.54
    diethyl ether 0.11
    m-xylene 0.08
    p-xylene 0.04
    chlorobenzene 0.02
    dimethyl carbonate 1.03
    n-octane 0.05
    formamide 61.95
    cyclopentanone 1.17
    2-pentanone 0.19
    anisole 0.09
    cyclopentyl methyl ether 0.54
    gamma-butyrolactone 1.95
    1-methoxy-2-propanol 5.27
    pyridine 0.52
    3-pentanone 0.3
    furfural 2.65
    n-dodecane 0.02
    diethylene glycol 8.34
    diisopropyl ether 0.04
    tert-amyl alcohol 0.36
    acetylacetone 0.46
    n-hexadecane 0.02
    acetophenone 0.23
    methyl propionate 0.53
    isopentyl acetate 0.06
    trichloroethylene 0.12
    n-nonanol 0.2
    cyclohexanol 0.74
    benzyl alcohol 0.28
    2-ethylhexanol 0.12
    isooctanol 0.15
    dipropyl ether 0.23
    1,2-dichlorobenzene 0.04
    ethyl lactate 0.68
    propylene carbonate 0.59
    n-methylformamide 13.31
    2-pentanol 0.2
    n-pentane 0.04
    1-propoxy-2-propanol 1.24
    1-methoxy-2-propyl acetate 0.5
    2-(2-methoxypropoxy) propanol 1.42
    mesitylene 0.07
    ε-caprolactone 0.9
    p-cymene 0.07
    epichlorohydrin 0.55
    1,1,1-trichloroethane 0.02
    2-aminoethanol 13.66
    morpholine-4-carbaldehyde 20.28
    sulfolane 18.82
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 0.34
    n-hexyl acetate 0.12
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 1.85
    sec-butyl acetate 0.04
    tert-butyl acetate 0.11
    decalin 0.03
    glycerin 56.15
    diglyme 3.07
    acrylic acid 3.85
    isopropyl myristate 0.05
    n-butyric acid 0.65
    acetyl acetate 0.13
    di(2-ethylhexyl) phthalate 0.12
    ethyl propionate 0.11
    nitromethane 4.43
    1,2-diethoxyethane 0.27
    benzonitrile 0.09
    trioctyl phosphate 0.13
    1-bromopropane 0.04
    gamma-valerolactone 4.4
    n-decanol 0.15
    triethyl phosphate 0.23
    4-methyl-2-pentanol 0.09
    propionitrile 0.16
    vinylene carbonate 0.65
    1,1,2-trichlorotrifluoroethane 6.23
    DMS 0.31
    cumene 0.03
    2-octanol 0.14
    2-hexanone 0.08
    octyl acetate 0.09
    limonene 0.14
    1,2-dimethoxyethane 1.41
    ethyl orthosilicate 0.19
    tributyl phosphate 0.11
    diacetone alcohol 0.95
    N,N-dimethylaniline 0.22
    acrylonitrile 0.4
    aniline 0.28
    1,3-propanediol 6.01
    bromobenzene 0.02
    dibromomethane 0.04
    1,1,2,2-tetrachloroethane 0.18
    2-methyl-cyclohexyl acetate 0.12
    tetrabutyl urea 0.34
    diisobutyl methanol 0.09
    2-phenylethanol 0.23
    styrene 0.03
    dioctyl adipate 0.13
    dimethyl sulfate 5.83
    ethyl butyrate 0.13
    methyl lactate 4.6
    butyl lactate 0.45
    diethyl carbonate 0.1
    propanediol butyl ether 2.14
    triethyl orthoformate 0.21
    p-tert-butyltoluene 0.08
    methyl 4-tert-butylbenzoate 0.59
    morpholine 2.03
    tert-butylamine 0.13
    n-dodecanol 0.11
    dimethoxymethane 3.53
    ethylene carbonate 0.42
    cyrene 4.05
    2-ethoxyethyl acetate 0.21
    2-ethylhexyl acetate 0.06
    1,2,4-trichlorobenzene 0.06
    4-methylpyridine 0.24
    dibutyl ether 0.09
    2,6-dimethyl-4-heptanol 0.09
    DEF 2.15
    dimethyl isosorbide 1.82
    tetrachloroethylene 0.19
    eugenol 0.66
    triacetin 0.4
    span 80 1.34
    1,4-butanediol 1.88
    1,1-dichloroethane 0.02
    2-methyl-1-pentanol 0.09
    methyl formate 4.51
    2-methyl-1-butanol 0.24
    n-decane 0.04
    butyronitrile 0.09
    3,7-dimethyl-1-octanol 0.09
    1-chlorooctane 0.05
    1-chlorotetradecane 0.02
    n-nonane 0.04
    undecane 0.03
    tert-butylcyclohexane 0.01
    cyclooctane 0.09
    cyclopentanol 0.85
    tetrahydropyran 0.34
    tert-amyl methyl ether 0.18
    2,5,8-trioxanonane 2.84
    1-hexene 0.03
    2-isopropoxyethanol 0.75
    2,2,2-trifluoroethanol 6.95
    methyl butyrate 0.16

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction