Molecular formula
C6H12O6

SMILES
C1[C@H]([C@H]([C@@H](C(O1)(CO)O)O)O)O

Fragrance
Sweet	65.25%
Odorless	57.68%
Caramellic	33.16%
Woody	32.83%
Clean	18.49%
Burnt	17.8%
Phenolic	17.79%
Vanilla	17.57%
Balsamic	16.72%
Alcoholic	16.71%

 

Flavor
Sweet	88.46%
Odorless	58.12%
Bitter	53.9%
Sweet-like	31.06%
Alcoholic	22.87%
Very slight	22.36%
Vanilla	22.26%
Cauliflower	21.91%
Soup	20.33%
Alkaline	20.03%

 

Odor impact est.
Low

XLogP3-AA
-2.8

pKa est.
5.43 (weak acid)

Molecular weight
180.16 g/mol

Vapor pressure est.

• hPa @ 20°C
• hPa @ 25°C

Evaporation rate
Ultra slow

Boiling point est.
768°C

Flash point

• 214.13 ˚C est.

Solubility expt.

• Solubility in water at 20 °C: good

• fructose
• D-fructopyranose
• D-fructose
• fructopyranose
• fructopyranoside
• d-fructopyranoside
• D-Fru
• D-Arabino-Hex-2-ulo-Pyranose
• fru
• CHEBI:37714
• fructosteril
• laevoral
• laevosan
• levugen
• UNII-R73GS1TJE0
• HSDB 526
• Fruchtzucker
• Fruktose
• Laevulose
• Levolose
• BRN 1423189
• arabino-hex-2-ulose
• [14C]-Fructose
• 4-01-00-04402 (Beilstein Handbook Reference)
• SCHEMBL239448
• (3S,4R,5R)-2-(hydroxymethyl)oxane-2,3,4,5-tetrol
• CHEMBL2325229
• CHEBI:15824
• CHEBI:28757
• LKDRXBCSQODPBY-VRPWFDPXSA-N
• AKOS004910390
• F0317
• C05003
• TOPIRAMATE IMPURITY, FRUCTOSE-(USP IMPURITY)
• Q27117234
• EB37038E-44A6-4AF7-B0D8-47A315AD2F74
• FRUCTOSE (CONSTITUENT OF CRANBERRY LIQUID PREPARATION)
• 200-333-3

D-Fructose is a monosaccharide with real-world applications across several sectors: used as a sweetener and humectant in foods and beverages to influence sweetness, solubility, and moisture retention; serves as a fermentation substrate for biotechnological processes to produce ethanol, organic acids, and other bio-based products; employed as a pharmaceutical excipient and sweetener in oral formulations such as syrups and chewable tablets; used in cosmetics and personal care as a humectant and moisture-retaining ingredient; and acts as a starting material for chemical synthesis, including dehydration to 5-hydroxymethylfurfural (HMF) for bio-based polymers and platform chemicals.

gpt-5-nano

Solvent	Solubility (g/L)
ethanol	13.42
methanol	78.85
isopropanol	5.37
water	1023.29
ethyl acetate	3.25
n-propanol	4.67
acetone	4.93
n-butanol	4.63
acetonitrile	1.98
DMF	284.37
toluene	0.65
isobutanol	2.94
1,4-dioxane	17.26
methyl acetate	1.54
THF	9.22
2-butanone	2.97
n-pentanol	3.48
sec-butanol	5.67
n-hexane	0.31
ethylene glycol	196.09
NMP	154.8
cyclohexane	1.53
DMSO	1024.58
n-butyl acetate	1.12
n-octanol	2.52
chloroform	0.7
n-propyl acetate	0.97
acetic acid	11.55
dichloromethane	1.4
cyclohexanone	6.98
propylene glycol	54.12
isopropyl acetate	2.08
DMAc	134.4
2-ethoxyethanol	37.77
isopentanol	3.11
n-heptane	1.57
ethyl formate	1.72
1,2-dichloroethane	2.0
n-hexanol	3.02
2-methoxyethanol	102.34
isobutyl acetate	0.41
tetrachloromethane	0.56
n-pentyl acetate	1.27
transcutol	24.26
n-heptanol	3.52
ethylbenzene	0.51
MIBK	2.21
2-propoxyethanol	18.0
tert-butanol	5.47
MTBE	2.1
2-butoxyethanol	11.88
propionic acid	5.85
o-xylene	1.56
formic acid	307.28
diethyl ether	3.03
m-xylene	1.1
p-xylene	0.55
chlorobenzene	0.32
dimethyl carbonate	7.07
n-octane	0.66
formamide	233.51
cyclopentanone	7.71
2-pentanone	3.58
anisole	1.45
cyclopentyl methyl ether	5.83
gamma-butyrolactone	10.34
1-methoxy-2-propanol	47.85
pyridine	3.06
3-pentanone	3.62
furfural	13.75
n-dodecane	0.31
diethylene glycol	63.6
diisopropyl ether	1.21
tert-amyl alcohol	5.52
acetylacetone	7.27
n-hexadecane	0.34
acetophenone	2.33
methyl propionate	5.75
isopentyl acetate	0.81
trichloroethylene	1.76
n-nonanol	2.38
cyclohexanol	7.57
benzyl alcohol	3.63
2-ethylhexanol	1.84
isooctanol	2.45
dipropyl ether	3.09
1,2-dichlorobenzene	0.53
ethyl lactate	5.21
propylene carbonate	3.24
n-methylformamide	61.66
2-pentanol	3.66
n-pentane	0.62
1-propoxy-2-propanol	10.37
1-methoxy-2-propyl acetate	5.02
2-(2-methoxypropoxy) propanol	9.87
mesitylene	1.17
ε-caprolactone	6.63
p-cymene	1.03
epichlorohydrin	6.77
1,1,1-trichloroethane	0.43
2-aminoethanol	78.83
morpholine-4-carbaldehyde	112.92
sulfolane	68.11
2,2,4-trimethylpentane	0.32
2-methyltetrahydrofuran	4.66
n-hexyl acetate	1.5
isooctane	0.2
2-(2-butoxyethoxy)ethanol	14.53
sec-butyl acetate	0.73
tert-butyl acetate	2.25
decalin	0.38
glycerin	212.6
diglyme	27.63
acrylic acid	10.55
isopropyl myristate	0.75
n-butyric acid	4.71
acetyl acetate	1.86
di(2-ethylhexyl) phthalate	1.35
ethyl propionate	1.62
nitromethane	20.98
1,2-diethoxyethane	3.37
benzonitrile	1.12
trioctyl phosphate	1.35
1-bromopropane	0.64
gamma-valerolactone	27.65
n-decanol	1.89
triethyl phosphate	1.74
4-methyl-2-pentanol	1.95
propionitrile	1.16
vinylene carbonate	3.09
1,1,2-trichlorotrifluoroethane	32.88
DMS	2.18
cumene	0.54
2-octanol	1.99
2-hexanone	1.23
octyl acetate	1.15
limonene	1.81
1,2-dimethoxyethane	19.91
ethyl orthosilicate	1.68
tributyl phosphate	0.95
diacetone alcohol	10.1
N,N-dimethylaniline	2.87
acrylonitrile	2.48
aniline	2.3
1,3-propanediol	49.53
bromobenzene	0.26
dibromomethane	0.77
1,1,2,2-tetrachloroethane	2.68
2-methyl-cyclohexyl acetate	1.1
tetrabutyl urea	2.72
diisobutyl methanol	1.79
2-phenylethanol	2.71
styrene	0.41
dioctyl adipate	1.31
dimethyl sulfate	27.57
ethyl butyrate	1.52
methyl lactate	22.76
butyl lactate	2.87
diethyl carbonate	0.9
propanediol butyl ether	13.65
triethyl orthoformate	1.97
p-tert-butyltoluene	1.09
methyl 4-tert-butylbenzoate	5.2
morpholine	25.48
tert-butylamine	2.38
n-dodecanol	1.5
dimethoxymethane	40.76
ethylene carbonate	2.65
cyrene	22.64
2-ethoxyethyl acetate	2.35
2-ethylhexyl acetate	0.72
1,2,4-trichlorobenzene	0.74
4-methylpyridine	2.22
dibutyl ether	1.26
2,6-dimethyl-4-heptanol	1.79
DEF	23.6
dimethyl isosorbide	13.83
tetrachloroethylene	2.74
eugenol	6.53
triacetin	3.16
span 80	8.57
1,4-butanediol	26.0
1,1-dichloroethane	0.56
2-methyl-1-pentanol	2.19
methyl formate	22.26
2-methyl-1-butanol	3.54
n-decane	0.55
butyronitrile	1.26
3,7-dimethyl-1-octanol	1.68
1-chlorooctane	0.83
1-chlorotetradecane	0.42
n-nonane	0.58
undecane	0.4
tert-butylcyclohexane	0.22
cyclooctane	1.12
cyclopentanol	7.48
tetrahydropyran	4.57
tert-amyl methyl ether	3.13
2,5,8-trioxanonane	24.62
1-hexene	0.39
2-isopropoxyethanol	13.62
2,2,2-trifluoroethanol	27.41
methyl butyrate	1.9

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