Cysteamine Hydrochloride

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  • Identifiers

    CAS number
    156-57-0

    Molecular formula
    C2H8ClNS

    SMILES
    C(CS)N.Cl

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fishy 63.97%
    Sulfurous 59.59%
    Meaty 54.23%
    Cheesy 42.44%
    Ripe 35.23%
    Savory 31.85%
    Garlic 31.22%
    Cooked 28.14%
    Onion 27.04%
    Roasted 25.86%

     

    Flavor
    Sulfurous 48.71%
    Meaty 46.46%
    Sulfury 43.37%
    Fishy 42.01%
    Onion 34.65%
    Ammoniacal 30.38%
    Roasted 30.05%
    Garlic 29.58%
    Egg 24.56%
    Burnt 24.56%

     

    Odor impact est.
    High

  • Properties

    pKa est.
    7.78 (neutral)

    Molecular weight
    113.61 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    137°C

    Flash point

    • 39.22 ˚C est.

    Solubility expt.

    • >17 [ug/mL] (The mean of the results at pH 7.4)

  • Synonyms

    • Cysteamine hydrochloride
    • 156-57-0
    • 2-Aminoethanethiol hydrochloride
    • Cysteamine HCl
    • Mercaptamine hydrochloride
    • Cysteaminium chloride
    • Bekaptan
    • ETHANETHIOL, 2-AMINO-, HYDROCHLORIDE
    • Mercaptoethylamine hydrochloride
    • Merkamin hydrochloride
    • Mercamine hydrochloride
    • Cysteamine chlorohydrate
    • Cysteaminhydrochlorid
    • Cystaran
    • IF1B771SVB
    • NSC-758692
    • CI-9148
    • CYSTADROPS
    • DTXSID8045779
    • NSC-21116
    • NSC-25116
    • DTXCID6025779
    • RefChem:54920
    • Hydrochloride, Cysteamine
    • 205-858-1
    • 2-Mercaptoethylamine hydrochloride
    • Cysteamine (Hydrochloride)
    • 2-aminoethane-1-thiol hydrochloride
    • 2-Thioethylamine hydrochloride
    • MFCD00012904
    • 2-aminoethanethiol;hydrochloride
    • Cysteamine hydrochloride [USAN]
    • beta-Mercaptoethylamine hydrochloride
    • C2H8ClNS
    • 2-Mercaptoethylammonium chloride
    • thioethanolamine hydrochloride
    • Decarboxy-cysteine hydrochloride
    • 2-Aminoethylmercaptan hydrochloride
    • NCGC00094090-01
    • 2-Mercaptoethylamine HCl
    • USAF EE-3
    • CAS-156-57-0
    • Cysteaminhydrochlorid [German]
    • CCRIS 3926
    • eta-Mercaptoethylamine hydrochloride
    • 1-Aminoethane-2-thiol hydrochloride
    • EINECS 205-858-1
    • NSC 21116
    • UNII-IF1B771SVB
    • 1-Amino-2-mercaptoethane hydrochloride
    • CI 9148
    • Ethylamine, 2-mercapto-, hydrochloride
    • cysteamine-hcl
    • AI3-26089
    • CCRIS 3619
    • beta-Mercaptoaethylamin chlorhydrat [German]
    • A-889
    • beta-Mercaptoaethylamin chlorhydrat
    • Cystadrops (TN)
    • Cystaran (TN)
    • Decarboxycystine HCl
    • Cym-H.HCl
    • cysteamine hydrochoride
    • Cimetidine Impurity 3
    • 2-aminoethanethiol hcl
    • 2-aminoethanethiol-hcl
    • cysteamine, hydrochloride
    • Spectrum2_001667
    • Spectrum3_000992
    • Spectrum4_001120
    • Spectrum5_001422
    • EC 205-858-1
    • SCHEMBL51598
    • KBioGR_001600
    • MLS000028734
    • Decarboxycysteine Hydrochloride
    • SPECTRUM1504226
    • 2-aminoethanthiol hydrochloride
    • SPBio_001853
    • Mercaptamine; MEA hydrochloride
    • MSK8079A
    • orb1300749
    • CHEMBL1256137
    • 2-amino-ethanethiol hydrochloride
    • 2-aminoethanethiol, hydrochloride
    • KBio3_001903
    • 2-mercaptoethanamine hydrochloride
    • A-Mercaptoethylamine hydrochloride
    • Cysteamine hydrochloride, BioXtra
    • CHEBI:201814
    • HMS1922H05
    • HMS5082P10
    • HMS6018N18
    • Pharmakon1600-01504226
    • Hydrochloric acid 2-aminoethanethiol
    • Tox21_111245
    • Tox21_500749
    • AC-301
    • CCG-39094
    • Cysteamine hydrochloride (JAN/USAN)
    • CYSTEAMINE HYDROCHLORIDE [MI]
    • EBC-02074
    • NSC758692
    • s4206
    • AKOS007929948
    • Tox21_111245_1
    • FA08270
    • LP00749
    • CYSTEAMINE HYDROCHLORIDE [VANDF]
    • NCGC00015691-06
    • NCGC00094090-02
    • NCGC00094090-03
    • NCGC00094090-04
    • NCGC00261434-01
    • AS-12111
    • HY-77591
    • MERCAPTAMINE HYDROCHLORIDE [MART.]
    • SMR000059101
    • Cysteamine hydrochloride, >=97.0% (RT)
    • MERCAPTAMINE HYDROCHLORIDE [WHO-DD]
    • DB-043323
    • A0296
    • Cysteamine hydrochloride, analytical standard
    • EU-0100749
    • SW219210-1
    • CYSTEAMINE HYDROCHLORIDE [ORANGE BOOK]
    • Cysteamine hydrochloride, >=98% (titration)
    • 156-57-0

  • Applications

    Cysteamine Hydrochloride (CAS 156-57-0) is a thiol-containing compound used primarily as a reducing agent and chemical intermediate across several industries. In cosmetics and personal care, it is employed in hair treatment formulations as a reducing agent to break keratin disulfide bonds during straightening and conditioning processes. In industrial manufacturing, it serves as a thiol-based reducing reagent and building block for polymer and epoxy resin formulations, enabling network formation and modification of adhesion properties. In pharmaceuticals and chemical synthesis, it functions as a versatile building block or intermediate for the preparation of active pharmaceutical ingredients and related compounds. In research and materials science, it is used as a ligand and surface-modifying reagent for nanomaterials and as a thiol-based reagent in catalyst and coating development. Subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 164.93
    methanol 457.66
    isopropanol 53.0
    water 159.6
    ethyl acetate 21.84
    n-propanol 89.77
    acetone 78.87
    n-butanol 70.77
    acetonitrile 40.26
    DMF 213.19
    toluene 3.54
    isobutanol 38.51
    1,4-dioxane 40.44
    methyl acetate 33.1
    THF 102.69
    2-butanone 37.13
    n-pentanol 35.03
    sec-butanol 32.05
    n-hexane 0.86
    ethylene glycol 165.62
    NMP 161.49
    cyclohexane 1.86
    DMSO 250.02
    n-butyl acetate 30.9
    n-octanol 12.59
    chloroform 27.48
    n-propyl acetate 17.18
    acetic acid 422.3
    dichloromethane 19.3
    cyclohexanone 60.05
    propylene glycol 114.36
    isopropyl acetate 10.48
    DMAc 114.85
    2-ethoxyethanol 85.97
    isopentanol 31.3
    n-heptane 2.4
    ethyl formate 58.75
    1,2-dichloroethane 11.39
    n-hexanol 38.79
    2-methoxyethanol 214.34
    isobutyl acetate 9.98
    tetrachloromethane 11.64
    n-pentyl acetate 17.41
    transcutol 98.78
    n-heptanol 24.14
    ethylbenzene 1.45
    MIBK 9.76
    2-propoxyethanol 94.47
    tert-butanol 35.14
    MTBE 8.78
    2-butoxyethanol 61.21
    propionic acid 130.13
    o-xylene 3.16
    formic acid 442.93
    diethyl ether 10.7
    m-xylene 2.64
    p-xylene 2.64
    chlorobenzene 9.22
    dimethyl carbonate 13.67
    n-octane 0.8
    formamide 333.42
    cyclopentanone 115.68
    2-pentanone 25.25
    anisole 7.08
    cyclopentyl methyl ether 22.81
    gamma-butyrolactone 131.35
    1-methoxy-2-propanol 88.29
    pyridine 45.87
    3-pentanone 16.41
    furfural 142.12
    n-dodecane 0.57
    diethylene glycol 135.72
    diisopropyl ether 2.22
    tert-amyl alcohol 26.01
    acetylacetone 32.27
    n-hexadecane 0.58
    acetophenone 13.52
    methyl propionate 24.91
    isopentyl acetate 16.88
    trichloroethylene 31.97
    n-nonanol 11.1
    cyclohexanol 31.1
    benzyl alcohol 21.75
    2-ethylhexanol 15.24
    isooctanol 14.29
    dipropyl ether 11.88
    1,2-dichlorobenzene 8.62
    ethyl lactate 22.22
    propylene carbonate 52.1
    n-methylformamide 212.87
    2-pentanol 19.7
    n-pentane 1.41
    1-propoxy-2-propanol 58.34
    1-methoxy-2-propyl acetate 27.26
    2-(2-methoxypropoxy) propanol 30.97
    mesitylene 1.81
    ε-caprolactone 51.94
    p-cymene 3.63
    epichlorohydrin 55.62
    1,1,1-trichloroethane 9.8
    2-aminoethanol 186.78
    morpholine-4-carbaldehyde 123.94
    sulfolane 150.87
    2,2,4-trimethylpentane 0.69
    2-methyltetrahydrofuran 37.46
    n-hexyl acetate 14.74
    isooctane 0.44
    2-(2-butoxyethoxy)ethanol 47.49
    sec-butyl acetate 6.71
    tert-butyl acetate 10.89
    decalin 0.61
    glycerin 214.18
    diglyme 72.22
    acrylic acid 165.19
    isopropyl myristate 5.21
    n-butyric acid 134.46
    acetyl acetate 19.64
    di(2-ethylhexyl) phthalate 12.1
    ethyl propionate 10.23
    nitromethane 267.29
    1,2-diethoxyethane 17.85
    benzonitrile 17.82
    trioctyl phosphate 9.67
    1-bromopropane 4.57
    gamma-valerolactone 130.53
    n-decanol 7.78
    triethyl phosphate 9.75
    4-methyl-2-pentanol 7.95
    propionitrile 24.7
    vinylene carbonate 53.43
    1,1,2-trichlorotrifluoroethane 134.12
    DMS 12.32
    cumene 1.5
    2-octanol 9.3
    2-hexanone 15.89
    octyl acetate 9.59
    limonene 5.77
    1,2-dimethoxyethane 55.05
    ethyl orthosilicate 8.97
    tributyl phosphate 10.27
    diacetone alcohol 31.81
    N,N-dimethylaniline 6.72
    acrylonitrile 47.76
    aniline 24.18
    1,3-propanediol 174.27
    bromobenzene 5.35
    dibromomethane 10.37
    1,1,2,2-tetrachloroethane 23.8
    2-methyl-cyclohexyl acetate 14.01
    tetrabutyl urea 14.75
    diisobutyl methanol 6.3
    2-phenylethanol 23.63
    styrene 2.4
    dioctyl adipate 11.27
    dimethyl sulfate 30.63
    ethyl butyrate 17.4
    methyl lactate 43.53
    butyl lactate 26.0
    diethyl carbonate 10.08
    propanediol butyl ether 50.45
    triethyl orthoformate 13.04
    p-tert-butyltoluene 3.6
    methyl 4-tert-butylbenzoate 19.53
    morpholine 68.64
    tert-butylamine 13.28
    n-dodecanol 5.65
    dimethoxymethane 47.39
    ethylene carbonate 37.53
    cyrene 40.69
    2-ethoxyethyl acetate 22.73
    2-ethylhexyl acetate 13.23
    1,2,4-trichlorobenzene 11.84
    4-methylpyridine 26.92
    dibutyl ether 5.86
    2,6-dimethyl-4-heptanol 6.3
    DEF 43.37
    dimethyl isosorbide 46.5
    tetrachloroethylene 32.1
    eugenol 29.33
    triacetin 20.62
    span 80 38.43
    1,4-butanediol 71.77
    1,1-dichloroethane 8.0
    2-methyl-1-pentanol 17.32
    methyl formate 121.25
    2-methyl-1-butanol 30.79
    n-decane 0.85
    butyronitrile 26.93
    3,7-dimethyl-1-octanol 8.33
    1-chlorooctane 2.73
    1-chlorotetradecane 1.26
    n-nonane 0.78
    undecane 0.66
    tert-butylcyclohexane 0.6
    cyclooctane 0.71
    cyclopentanol 62.67
    tetrahydropyran 25.09
    tert-amyl methyl ether 7.33
    2,5,8-trioxanonane 55.47
    1-hexene 2.67
    2-isopropoxyethanol 37.0
    2,2,2-trifluoroethanol 145.19
    methyl butyrate 19.75

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction