Cyromazine

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  • Identifiers

    CAS number
    66215-27-8

    Molecular formula
    C6H10N6

    SMILES
    C1CC1NC2=NC(=NC(=N2)N)N

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 50.6%
    Fishy 31.7%
    Meaty 28.02%
    Animal 25.12%
    Nutty 24.1%
    Cheesy 23.41%
    Roasted 23.25%
    Savory 21.73%
    Cooked 21.45%
    Burnt 20.02%

     

    Flavor
    Bitter 69.02%
    Odorless 32.94%
    Roasted 23.31%
    Sweet-like 19.85%
    Bland 19.84%
    Scallion 19.4%
    Alkaline 19.38%
    Cereal 18.99%
    Mild 18.65%
    Nitrile 18.6%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.2

    pKa est.
    5.48 (weak acid)

    Molecular weight
    166.18 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    498°C

    Melting point expt.

    • 224.9 °C
    • 219 - 222 °C

    Flash point

    • 241.15 ˚C est.

    Solubility expt.

    • All in g/kg, 20 °C: In methanol 22, isopropanol, 2.5, acetone, 1.7, n-octanol 1.2, dichloromethane 0.25, toluene, 0.015, hexane 0.0002
    • In water, 1.30X10+4 mg/L at 25 °C, pH 7.1
    • In water, 1.1% at 20 °C (pH 7.5); methanol 1.7%
    • 1.30E+04 mg/L @ 25 °C (exp)

  • Synonyms

    • CYROMAZINE
    • 66215-27-8
    • Larvadex
    • Neporex
    • Vetrazin
    • Trigard
    • Cyromazin
    • Cyclopropylmelamine
    • Citation
    • Cypromazine
    • Azimethiphos
    • Cga 72662
    • N-Cyclopropyl-1,3,5-triazine-2,4,6-triamine
    • Ciromazina
    • Armor
    • 1,3,5-Triazine-2,4,6-triamine, N-cyclopropyl-
    • 2-Cyclopropylamino-4,6-diamino-s-triazine
    • N-cyclopropylmelamine
    • Vetrazin (pesticide)
    • N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine
    • Cyromazinum
    • 2-N-cyclopropyl-1,3,5-triazine-2,4,6-triamine
    • CGA-72662
    • 2,4-Diamino-6-(cyclopropylamino)-s-triazine
    • AI3-52713
    • NSC-759268
    • CA49Y29RA9
    • DTXSID6023999
    • DTXCID403999
    • CHEBI:30260
    • N(2)-cyclopropyl-1,3,5-triazine-2,4,6-triamine
    • RefChem:919489
    • 266-257-8
    • Larvadex Premix
    • OMS-2014
    • N-Cyclopropyl-2,4,6-triamino-1,3,5-triazine
    • C6H10N6
    • MFCD00078650
    • Neporex (TN)
    • Cyromazine [ANSI:BSI:ISO]
    • Cyromazin;CGA-72662
    • Cyromazine (INN)
    • N~2~-Cyclopropyl-1,3,5-Triazine-2,4,6-Triamine
    • N-cyclopropyltriazine-2,4,6-triamine
    • Diamino-6-(cyclopropylamino)-s-triazine
    • NCGC00163803-03
    • CYROMAZINE [INN]
    • Cyclopropyl-1,3,5-triazine-2,4,6-triamine
    • 2,4-diamino-6-cyclopropylamino-1,3,5-triazine
    • Caswell No. 167B
    • Cyromazine [BAN:INN]
    • Cyromazinum [INN-Latin]
    • Ciromazina [INN-Spanish]
    • CAS-66215-27-8
    • HSDB 6602
    • EINECS 266-257-8
    • BRN 0882879
    • UNII-CA49Y29RA9
    • Cyromazine [USP:INN:BAN]
    • Neoprex
    • AX3
    • Cyromazine (Standard)
    • N2-Cyclopropylmelamine
    • CYROMAZINE [MI]
    • Cyromazine 100 microg/mL in Acetonitrile
    • Cyromazine (USP/INN)
    • CYROMAZINE [ISO]
    • CYROMAZINE [HSDB]
    • N-Cyclopropyl-1,3,5-triazin-2,4,6-triamine
    • CYROMAZINE [MART.]
    • CYROMAZINE [USP-RS]
    • SCHEMBL27231
    • 2,4-Diamino-6-(cyclopropylamino)-s-triazine (8CI)
    • orb1310241
    • CHEMBL1231107
    • HY-B1331R
    • CYROMAZINE [USP IMPURITY]
    • HMS3264K09
    • HMS3652N03
    • HMS5082D04
    • Pharmakon1600-01505903
    • HY-B1331
    • MSK20403
    • Tox21_112074
    • Tox21_201846
    • Tox21_300784
    • EBC-04334
    • NSC759268
    • s4167
    • AKOS007930524
    • Tox21_112074_1
    • AC-6858
    • CCG-213992
    • CS-4864
    • FC20765
    • NSC 759268
    • Cyromazine-(cyclopropyl-2,2,3,3-d4)
    • NCGC00163803-01
    • NCGC00163803-02
    • NCGC00163803-04
    • NCGC00163803-05
    • NCGC00163803-06
    • NCGC00254688-01
    • NCGC00259395-01
    • 2Cyclopropylamino-4,6-diamino-s-triazine
    • AS-12700
    • SY052504
    • 2,4-diamino-6-cyclopropylamino-s-triazine
    • DB-054884
    • C2366
    • NS00001536
    • SW220183-1
    • Cyromazin, PESTANAL(R), analytical standard
    • D07767
    • D89506
    • EN300-872806
    • AB01563373_01
    • AB01563373_02
    • 215C278
    • Q412423
    • SR-01000944274
    • 2,4-Diamino-6-(cyclopropylamino)-1,3,5-triazine
    • SR-01000944274-1
    • BRD-K36711084-001-01-2
    • BRD-K36711084-001-02-0
    • N-Cyclopropyl-1,3,5-triazine-2,4,6-triamine, 9CI
    • N-Cyclopropyl-2,4,6-triamino-1,3,5-triazine, 97%
    • 66215-27-8

  • Applications

    Cyromazine is a triazine insect growth regulator used primarily as a larvicide to suppress Diptera populations in agricultural, veterinary, and household settings. In practice, it is applied in livestock housing and manure or litter management to prevent emergence of fly larvae; it is formulated into veterinary and farm sanitation products such as sprays, baits, and treated materials to reduce nuisance flies in barns, kennels, and poultry houses; it is used in greenhouse and nursery IPM programs to control fly larvae in organic waste substrates and spent media; and it appears in consumer and professional household pest control products aimed at reducing fly problems in kitchens, storage areas, and other indoor spaces, all subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 4.04
    methanol 9.43
    isopropanol 1.63
    water 12.56
    ethyl acetate 2.84
    n-propanol 2.69
    acetone 1.79
    n-butanol 2.16
    acetonitrile 1.68
    DMF 25.4
    toluene 0.27
    isobutanol 1.25
    1,4-dioxane 3.78
    methyl acetate 3.32
    THF 7.89
    2-butanone 1.63
    n-pentanol 1.74
    sec-butanol 1.02
    n-hexane 0.04
    ethylene glycol 20.16
    NMP 38.84
    cyclohexane 0.06
    DMSO 36.95
    n-butyl acetate 2.17
    n-octanol 0.47
    chloroform 1.25
    n-propyl acetate 2.1
    acetic acid 39.13
    dichloromethane 1.33
    cyclohexanone 3.83
    propylene glycol 18.78
    isopropyl acetate 1.43
    DMAc 21.09
    2-ethoxyethanol 10.23
    isopentanol 1.28
    n-heptane 0.06
    ethyl formate 6.57
    1,2-dichloroethane 0.81
    n-hexanol 1.41
    2-methoxyethanol 28.11
    isobutyl acetate 1.24
    tetrachloromethane 0.37
    n-pentyl acetate 1.16
    transcutol 7.12
    n-heptanol 0.62
    ethylbenzene 0.14
    MIBK 0.92
    2-propoxyethanol 10.99
    tert-butanol 1.21
    MTBE 0.3
    2-butoxyethanol 4.7
    propionic acid 17.96
    o-xylene 0.24
    formic acid 50.77
    diethyl ether 0.44
    m-xylene 0.23
    p-xylene 0.25
    chlorobenzene 0.59
    dimethyl carbonate 6.45
    n-octane 0.02
    formamide 42.1
    cyclopentanone 7.78
    2-pentanone 1.41
    anisole 0.66
    cyclopentyl methyl ether 1.63
    gamma-butyrolactone 23.47
    1-methoxy-2-propanol 14.6
    pyridine 3.52
    3-pentanone 1.06
    furfural 25.42
    n-dodecane 0.02
    diethylene glycol 22.59
    diisopropyl ether 0.14
    tert-amyl alcohol 0.87
    acetylacetone 3.85
    n-hexadecane 0.03
    acetophenone 1.73
    methyl propionate 4.54
    isopentyl acetate 1.62
    trichloroethylene 2.01
    n-nonanol 0.51
    cyclohexanol 1.47
    benzyl alcohol 2.46
    2-ethylhexanol 0.75
    isooctanol 0.46
    dipropyl ether 0.61
    1,2-dichlorobenzene 0.66
    ethyl lactate 6.01
    propylene carbonate 13.72
    n-methylformamide 20.3
    2-pentanol 0.83
    n-pentane 0.04
    1-propoxy-2-propanol 5.73
    1-methoxy-2-propyl acetate 5.05
    2-(2-methoxypropoxy) propanol 5.08
    mesitylene 0.18
    ε-caprolactone 7.09
    p-cymene 0.25
    epichlorohydrin 9.0
    1,1,1-trichloroethane 0.6
    2-aminoethanol 15.72
    morpholine-4-carbaldehyde 27.85
    sulfolane 37.48
    2,2,4-trimethylpentane 0.03
    2-methyltetrahydrofuran 2.47
    n-hexyl acetate 1.25
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 5.76
    sec-butyl acetate 1.02
    tert-butyl acetate 1.31
    decalin 0.04
    glycerin 49.46
    diglyme 7.7
    acrylic acid 31.97
    isopropyl myristate 0.53
    n-butyric acid 11.44
    acetyl acetate 3.76
    di(2-ethylhexyl) phthalate 2.2
    ethyl propionate 1.95
    nitromethane 32.0
    1,2-diethoxyethane 1.01
    benzonitrile 1.9
    trioctyl phosphate 1.44
    1-bromopropane 0.31
    gamma-valerolactone 22.29
    n-decanol 0.43
    triethyl phosphate 2.05
    4-methyl-2-pentanol 0.56
    propionitrile 1.37
    vinylene carbonate 14.28
    1,1,2-trichlorotrifluoroethane 29.56
    DMS 3.58
    cumene 0.15
    2-octanol 0.32
    2-hexanone 1.19
    octyl acetate 0.91
    limonene 0.31
    1,2-dimethoxyethane 6.27
    ethyl orthosilicate 1.5
    tributyl phosphate 1.6
    diacetone alcohol 4.38
    N,N-dimethylaniline 0.63
    acrylonitrile 3.39
    aniline 1.64
    1,3-propanediol 14.36
    bromobenzene 0.35
    dibromomethane 0.63
    1,1,2,2-tetrachloroethane 1.87
    2-methyl-cyclohexyl acetate 1.76
    tetrabutyl urea 2.13
    diisobutyl methanol 0.42
    2-phenylethanol 2.07
    styrene 0.17
    dioctyl adipate 1.55
    dimethyl sulfate 16.85
    ethyl butyrate 1.91
    methyl lactate 17.09
    butyl lactate 3.75
    diethyl carbonate 2.18
    propanediol butyl ether 5.68
    triethyl orthoformate 1.85
    p-tert-butyltoluene 0.23
    methyl 4-tert-butylbenzoate 2.79
    morpholine 6.44
    tert-butylamine 0.4
    n-dodecanol 0.34
    dimethoxymethane 8.66
    ethylene carbonate 9.67
    cyrene 11.48
    2-ethoxyethyl acetate 2.69
    2-ethylhexyl acetate 1.29
    1,2,4-trichlorobenzene 1.19
    4-methylpyridine 2.11
    dibutyl ether 0.28
    2,6-dimethyl-4-heptanol 0.42
    DEF 4.17
    dimethyl isosorbide 8.7
    tetrachloroethylene 1.4
    eugenol 4.05
    triacetin 3.46
    span 80 5.57
    1,4-butanediol 7.08
    1,1-dichloroethane 0.5
    2-methyl-1-pentanol 1.14
    methyl formate 17.66
    2-methyl-1-butanol 1.24
    n-decane 0.03
    butyronitrile 1.33
    3,7-dimethyl-1-octanol 0.48
    1-chlorooctane 0.12
    1-chlorotetradecane 0.07
    n-nonane 0.03
    undecane 0.03
    tert-butylcyclohexane 0.03
    cyclooctane 0.03
    cyclopentanol 3.35
    tetrahydropyran 1.32
    tert-amyl methyl ether 0.39
    2,5,8-trioxanonane 7.04
    1-hexene 0.16
    2-isopropoxyethanol 4.43
    2,2,2-trifluoroethanol 22.14
    methyl butyrate 2.86

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction