Cyclosarin

Overview IFRA Request a quote

  • Identifiers

    CAS number
    329-99-7

    Molecular formula
    C7H14FO2P

    SMILES
    CP(=O)(OC1CCCCC1)F

  • Odor profile

    Fragrance
    Fruity 53.67%
    Green 30.07%
    Sweet 29.85%
    Herbal 28.86%
    Mint 26.93%
    Fresh 26.06%
    Odorless 26.0%
    Tropical 25.25%
    Floral 23.59%
    Cooling 22.07%

     

    Flavor
    Odorless 30.73%
    Sulfurous 23.87%
    Fruity 23.74%
    Sulfury 22.61%
    Bouillon 20.8%
    Mild 20.48%
    Stinky 20.29%
    Mousy 19.81%
    Alkaline 19.52%
    Scallion 19.48%

     

    Odor impact est.
    Medium

    Odor threshold

    • Has an odor threshold between about 10.4 mg/cu m and 14.8 mg/cu m

  • Properties

    XLogP3-AA
    1.8

    pKa est.
    6.0 (neutral)

    Molecular weight
    180.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Melting point expt.

    • -30 °C

    Boiling point

    • 239 °C

    Flash point

    • 100.75 ˚C est.

    Solubility expt.

    • In water, 3,700 mg/L at 20 °C

  • Synonyms

    • Cyclosarin
    • CF Me ester
    • Cyclohexyl methylphosphonofluoridate
    • 329-99-7
    • [fluoro(methyl)phosphoryl]oxycyclohexane
    • GF (chemical warfare agent)
    • O-Cyclohexyl methylphosphonofluoridate
    • Methyl cyclohexylfluorophosphonate
    • UNII-VM36F9N236
    • BRN 2327087
    • Phosphonofluoridic acid, methyl-, cyclohexyl ester
    • HSDB 7597
    • VM36F9N236
    • CYCLOSARIN [HSDB]
    • DTXSID00861875
    • CMPF ester
    • GF cpd
    • cyclohexylmethylphosphonofluoridate
    • Cyclosin (chemical warfare agent)
    • EA 1212
    • cyclohexylsarin
    • SCHEMBL93674
    • G-SERIES NERVE AGENT GF
    • CHEMBL4066149
    • DTXCID50810732
    • AKOS006277928
    • Cyclohexyl methylphosphonofluoridoate #
    • Cyclohexyl methylphosphonofluoridate (GF)
    • PD194891
    • NS00076167
    • Q418763
    • Methylphosphonic acid, fluoroanhydride, cyclohexyl ester

  • Applications

    Cyclosarin, CAS 329-99-7, is a highly toxic nerve agent in the G-series with no recognized civilian industrial or commercial applications. Because of its dangerous properties and strict international regulations, production, possession, or use of Cyclosarin is prohibited, and related information is typically confined to historical context and chemical weapons control; any discussion should be limited to safety, regulatory compliance, and lawful handling under local laws.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 596.5
    methanol 1197.44
    isopropanol 423.03
    water 44.2
    ethyl acetate 94.9
    n-propanol 440.78
    acetone 242.02
    n-butanol 304.83
    acetonitrile 199.72
    DMF 625.98
    toluene 99.51
    isobutanol 263.62
    1,4-dioxane 320.03
    methyl acetate 114.18
    THF 441.53
    2-butanone 141.29
    n-pentanol 203.59
    sec-butanol 276.34
    n-hexane 25.38
    ethylene glycol 431.35
    NMP 374.34
    cyclohexane 58.46
    DMSO 665.37
    n-butyl acetate 81.38
    n-octanol 115.91
    chloroform 706.98
    n-propyl acetate 74.01
    acetic acid 311.1
    dichloromethane 536.35
    cyclohexanone 277.74
    propylene glycol 415.27
    isopropyl acetate 68.75
    DMAc 265.09
    2-ethoxyethanol 269.08
    isopentanol 176.54
    n-heptane 25.24
    ethyl formate 143.69
    1,2-dichloroethane 274.24
    n-hexanol 213.03
    2-methoxyethanol 575.83
    isobutyl acetate 49.66
    tetrachloromethane 71.77
    n-pentyl acetate 85.0
    transcutol 344.65
    n-heptanol 115.9
    ethylbenzene 55.26
    MIBK 86.41
    2-propoxyethanol 334.81
    tert-butanol 301.39
    MTBE 92.45
    2-butoxyethanol 186.55
    propionic acid 259.41
    o-xylene 77.92
    formic acid 308.26
    diethyl ether 125.46
    m-xylene 79.9
    p-xylene 64.23
    chlorobenzene 133.58
    dimethyl carbonate 57.57
    n-octane 13.8
    formamide 370.4
    cyclopentanone 320.7
    2-pentanone 124.84
    anisole 99.62
    cyclopentyl methyl ether 160.95
    gamma-butyrolactone 332.0
    1-methoxy-2-propanol 398.64
    pyridine 293.74
    3-pentanone 86.54
    furfural 370.76
    n-dodecane 12.39
    diethylene glycol 374.14
    diisopropyl ether 37.02
    tert-amyl alcohol 191.12
    acetylacetone 141.09
    n-hexadecane 13.41
    acetophenone 107.85
    methyl propionate 104.01
    isopentyl acetate 74.03
    trichloroethylene 419.2
    n-nonanol 99.44
    cyclohexanol 269.97
    benzyl alcohol 147.74
    2-ethylhexanol 93.06
    isooctanol 84.67
    dipropyl ether 76.78
    1,2-dichlorobenzene 129.3
    ethyl lactate 87.45
    propylene carbonate 180.33
    n-methylformamide 414.06
    2-pentanol 171.16
    n-pentane 42.13
    1-propoxy-2-propanol 191.3
    1-methoxy-2-propyl acetate 103.81
    2-(2-methoxypropoxy) propanol 138.08
    mesitylene 57.91
    ε-caprolactone 208.67
    p-cymene 45.86
    epichlorohydrin 320.2
    1,1,1-trichloroethane 164.92
    2-aminoethanol 557.75
    morpholine-4-carbaldehyde 364.19
    sulfolane 466.54
    2,2,4-trimethylpentane 13.78
    2-methyltetrahydrofuran 217.34
    n-hexyl acetate 118.01
    isooctane 12.08
    2-(2-butoxyethoxy)ethanol 200.49
    sec-butyl acetate 44.87
    tert-butyl acetate 78.93
    decalin 19.48
    glycerin 508.8
    diglyme 272.62
    acrylic acid 262.4
    isopropyl myristate 53.98
    n-butyric acid 223.58
    acetyl acetate 70.63
    di(2-ethylhexyl) phthalate 69.29
    ethyl propionate 70.09
    nitromethane 321.33
    1,2-diethoxyethane 97.13
    benzonitrile 165.51
    trioctyl phosphate 58.97
    1-bromopropane 159.54
    gamma-valerolactone 397.58
    n-decanol 78.14
    triethyl phosphate 48.36
    4-methyl-2-pentanol 87.28
    propionitrile 185.73
    vinylene carbonate 190.04
    1,1,2-trichlorotrifluoroethane 325.67
    DMS 79.21
    cumene 40.56
    2-octanol 85.34
    2-hexanone 87.31
    octyl acetate 71.0
    limonene 59.81
    1,2-dimethoxyethane 273.52
    ethyl orthosilicate 48.45
    tributyl phosphate 58.41
    diacetone alcohol 144.18
    N,N-dimethylaniline 88.05
    acrylonitrile 251.99
    aniline 162.74
    1,3-propanediol 431.39
    bromobenzene 123.49
    dibromomethane 391.2
    1,1,2,2-tetrachloroethane 381.63
    2-methyl-cyclohexyl acetate 76.59
    tetrabutyl urea 85.84
    diisobutyl methanol 61.24
    2-phenylethanol 138.74
    styrene 64.67
    dioctyl adipate 73.79
    dimethyl sulfate 110.39
    ethyl butyrate 67.09
    methyl lactate 140.36
    butyl lactate 105.56
    diethyl carbonate 51.94
    propanediol butyl ether 209.34
    triethyl orthoformate 56.96
    p-tert-butyltoluene 46.63
    methyl 4-tert-butylbenzoate 125.61
    morpholine 388.63
    tert-butylamine 199.72
    n-dodecanol 61.25
    dimethoxymethane 276.08
    ethylene carbonate 152.97
    cyrene 151.69
    2-ethoxyethyl acetate 96.51
    2-ethylhexyl acetate 58.67
    1,2,4-trichlorobenzene 149.02
    4-methylpyridine 212.02
    dibutyl ether 63.14
    2,6-dimethyl-4-heptanol 61.24
    DEF 156.29
    dimethyl isosorbide 199.33
    tetrachloroethylene 250.69
    eugenol 149.96
    triacetin 109.5
    span 80 157.42
    1,4-butanediol 207.78
    1,1-dichloroethane 237.83
    2-methyl-1-pentanol 123.53
    methyl formate 251.34
    2-methyl-1-butanol 177.79
    n-decane 18.3
    butyronitrile 173.78
    3,7-dimethyl-1-octanol 91.22
    1-chlorooctane 59.84
    1-chlorotetradecane 27.59
    n-nonane 17.97
    undecane 14.64
    tert-butylcyclohexane 16.13
    cyclooctane 19.84
    cyclopentanol 336.55
    tetrahydropyran 256.72
    tert-amyl methyl ether 74.84
    2,5,8-trioxanonane 213.35
    1-hexene 65.88
    2-isopropoxyethanol 148.42
    2,2,2-trifluoroethanol 134.98
    methyl butyrate 93.74

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction