Cyclomulberrin

Overview IFRA Request a quote

  • Identifiers

    CAS number
    19275-51-5

    Molecular formula
    C25H24O6

    SMILES
    CC(=CCC1=C2C(=C(C=C1O)O)C(=O)C3=C(O2)C4=C(C=C(C=C4)O)OC3C=C(C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Phenolic 44.79%
    Spicy 40.84%
    Woody 30.69%
    Herbal 28.11%
    Fruity 27.98%
    Odorless 26.05%
    Dry 24.05%
    Smoky 24.01%
    Sweet 23.57%
    Medicinal 23.16%

     

    Flavor
    Bitter 92.82%
    Cedarleaf 19.74%
    Lovage 19.22%
    Parsley 19.1%
    Nitrile 18.02%
    Heather 17.82%
    Ripe apricot 17.79%
    Red fruit 17.7%
    Basil 17.68%
    Broom 17.65%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.8

    pKa est.
    10.1 (weak base)

    Molecular weight
    420.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1457°C

    Melting point expt.

    • 245 - 246 °C

    Flash point

    • 270.26 ˚C est.

  • Synonyms

    • Cyclomulberrin
    • 19275-51-5
    • CHEBI:132869
    • 3,8,10-trihydroxy-11-(3-methylbut-2-enyl)-6-(2-methylprop-1-enyl)-6H-chromeno[4,3-b]chromen-7-one
    • 3,8,10-trihydroxy-11-(3-methylbut-2-en-1-yl)-6-(2-methylprop-1-en-1-yl)-6H,7H-chromeno[4,3-b]chromen-7-one
    • 3,8,10-trihydroxy-11-(3-methylbut-2-en-1-yl)-6-(2-methylprop-1-en-1-yl)-6H,7H-chromeno(4,3-b)chromen-7-one
    • 3,8,10-trihydroxy-11-(3-methylbut-2-enyl)-6-(2-methylprop-1-enyl)-6H-chromeno(4,3-b)chromen-7-one
    • RefChem:129782
    • CHEMBL4168522
    • orb1991328
    • SCHEMBL27013596
    • DTXSID301317405
    • BDBM50291296
    • HY-N12514
    • LMPK12110932
    • FS-7737
    • CS-0927591
    • 3,8,10-Trihydroxy-11-(3-methyl-2-butenyl)-6-(2-methyl-1-propenyl)-6H,7H-[1]benzopyrano[4,3-b][1]benzopyran-7-one, 9CI
    • 3,8,10-Trihydroxy-11-(3-methylbut-2-en-1-yl)-6-(2-methylprop-1-en-1-yl)-6H,7H-[1]benzopyrano[3,2-c][1]benzopyran-7-one
    • 19275-51-5

  • Applications

    Cyclomulberrin (CAS 19275-51-5) is regarded as having potential applications across multiple industries, commonly contemplated as an aroma ingredient or fixative in perfumery and cosmetics/personal care; may be used as an intermediate or solvent in industrial manufacturing; employed as a stabilizer or processing aid in polymers and coatings, and as an additive in ink and paint formulations; considered for specialty cleaning formulations as a solvent component or additive; and may serve as a chemical intermediate in synthetic routes, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 4.8
    methanol 5.53
    isopropanol 4.26
    water 0.01
    ethyl acetate 8.65
    n-propanol 6.82
    acetone 19.97
    n-butanol 4.7
    acetonitrile 7.0
    DMF 94.57
    toluene 2.89
    isobutanol 4.89
    1,4-dioxane 22.25
    methyl acetate 16.71
    THF 65.36
    2-butanone 22.26
    n-pentanol 4.98
    sec-butanol 4.65
    n-hexane 0.1
    ethylene glycol 6.64
    NMP 148.9
    cyclohexane 0.15
    DMSO 115.59
    n-butyl acetate 11.99
    n-octanol 3.31
    chloroform 23.7
    n-propyl acetate 11.02
    acetic acid 40.68
    dichloromethane 17.58
    cyclohexanone 34.37
    propylene glycol 16.09
    isopropyl acetate 7.03
    DMAc 129.23
    2-ethoxyethanol 23.18
    isopentanol 4.54
    n-heptane 0.13
    ethyl formate 9.49
    1,2-dichloroethane 12.27
    n-hexanol 3.74
    2-methoxyethanol 46.43
    isobutyl acetate 9.25
    tetrachloromethane 1.29
    n-pentyl acetate 11.76
    transcutol 118.64
    n-heptanol 3.97
    ethylbenzene 1.52
    MIBK 7.98
    2-propoxyethanol 36.4
    tert-butanol 5.41
    MTBE 3.45
    2-butoxyethanol 22.98
    propionic acid 21.0
    o-xylene 1.97
    formic acid 15.0
    diethyl ether 2.48
    m-xylene 2.0
    p-xylene 2.77
    chlorobenzene 5.87
    dimethyl carbonate 20.14
    n-octane 0.08
    formamide 20.74
    cyclopentanone 69.46
    2-pentanone 12.08
    anisole 7.02
    cyclopentyl methyl ether 11.87
    gamma-butyrolactone 87.06
    1-methoxy-2-propanol 39.84
    pyridine 25.84
    3-pentanone 10.38
    furfural 57.21
    n-dodecane 0.13
    diethylene glycol 36.28
    diisopropyl ether 0.89
    tert-amyl alcohol 5.05
    acetylacetone 24.64
    n-hexadecane 0.15
    acetophenone 14.79
    methyl propionate 18.29
    isopentyl acetate 13.6
    trichloroethylene 45.34
    n-nonanol 3.75
    cyclohexanol 5.43
    benzyl alcohol 11.52
    2-ethylhexanol 3.13
    isooctanol 3.81
    dipropyl ether 3.7
    1,2-dichlorobenzene 6.03
    ethyl lactate 16.13
    propylene carbonate 35.72
    n-methylformamide 29.79
    2-pentanol 2.67
    n-pentane 0.08
    1-propoxy-2-propanol 28.91
    1-methoxy-2-propyl acetate 30.1
    2-(2-methoxypropoxy) propanol 34.73
    mesitylene 1.07
    ε-caprolactone 37.2
    p-cymene 1.93
    epichlorohydrin 76.63
    1,1,1-trichloroethane 9.29
    2-aminoethanol 11.62
    morpholine-4-carbaldehyde 106.1
    sulfolane 170.07
    2,2,4-trimethylpentane 0.12
    2-methyltetrahydrofuran 19.51
    n-hexyl acetate 12.16
    isooctane 0.08
    2-(2-butoxyethoxy)ethanol 41.45
    sec-butyl acetate 7.33
    tert-butyl acetate 10.02
    decalin 0.18
    glycerin 39.24
    diglyme 64.42
    acrylic acid 30.36
    isopropyl myristate 5.56
    n-butyric acid 18.1
    acetyl acetate 9.12
    di(2-ethylhexyl) phthalate 10.52
    ethyl propionate 9.28
    nitromethane 70.2
    1,2-diethoxyethane 16.17
    benzonitrile 10.73
    trioctyl phosphate 6.79
    1-bromopropane 3.47
    gamma-valerolactone 124.84
    n-decanol 2.78
    triethyl phosphate 8.76
    4-methyl-2-pentanol 2.3
    propionitrile 7.41
    vinylene carbonate 31.48
    1,1,2-trichlorotrifluoroethane 98.97
    DMS 24.58
    cumene 1.28
    2-octanol 2.55
    2-hexanone 11.76
    octyl acetate 7.7
    limonene 2.21
    1,2-dimethoxyethane 31.9
    ethyl orthosilicate 7.3
    tributyl phosphate 8.92
    diacetone alcohol 24.75
    N,N-dimethylaniline 6.67
    acrylonitrile 14.45
    aniline 8.97
    1,3-propanediol 14.47
    bromobenzene 4.62
    dibromomethane 7.93
    1,1,2,2-tetrachloroethane 37.83
    2-methyl-cyclohexyl acetate 12.29
    tetrabutyl urea 13.46
    diisobutyl methanol 2.48
    2-phenylethanol 11.9
    styrene 2.02
    dioctyl adipate 12.6
    dimethyl sulfate 50.4
    ethyl butyrate 9.59
    methyl lactate 34.06
    butyl lactate 19.92
    diethyl carbonate 7.66
    propanediol butyl ether 30.0
    triethyl orthoformate 10.47
    p-tert-butyltoluene 1.94
    methyl 4-tert-butylbenzoate 21.26
    morpholine 36.81
    tert-butylamine 1.6
    n-dodecanol 2.06
    dimethoxymethane 38.89
    ethylene carbonate 22.36
    cyrene 44.36
    2-ethoxyethyl acetate 24.47
    2-ethylhexyl acetate 9.98
    1,2,4-trichlorobenzene 13.02
    4-methylpyridine 19.48
    dibutyl ether 3.46
    2,6-dimethyl-4-heptanol 2.48
    DEF 21.93
    dimethyl isosorbide 62.91
    tetrachloroethylene 14.42
    eugenol 23.4
    triacetin 29.66
    span 80 27.12
    1,4-butanediol 6.12
    1,1-dichloroethane 8.76
    2-methyl-1-pentanol 4.94
    methyl formate 24.88
    2-methyl-1-butanol 4.77
    n-decane 0.18
    butyronitrile 5.45
    3,7-dimethyl-1-octanol 4.01
    1-chlorooctane 1.16
    1-chlorotetradecane 0.63
    n-nonane 0.13
    undecane 0.15
    tert-butylcyclohexane 0.17
    cyclooctane 0.06
    cyclopentanol 11.33
    tetrahydropyran 11.21
    tert-amyl methyl ether 3.54
    2,5,8-trioxanonane 50.7
    1-hexene 0.67
    2-isopropoxyethanol 15.94
    2,2,2-trifluoroethanol 14.17
    methyl butyrate 13.58

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction