Cyclomammeisin

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  • Identifiers

    CAS number
    30563-62-3

    Molecular formula
    C25H26O6

    SMILES
    CC(C)CC(=O)C1=C2C(=C3C(=C1O)C(=CC(=O)O3)C4=CC=CC=C4)CC(O2)C(C)(C)O

    Safety labels

  • Odor profile

    Fragrance
    Fruity 34.34%
    Sweet 33.02%
    Odorless 30.4%
    Animal 27.95%
    Musk 26.94%
    Dry 26.28%
    Floral 26.0%
    Balsamic 25.32%
    Powdery 24.39%
    Woody 24.24%

     

    Flavor
    Bitter 87.69%
    Odorless 22.04%
    Bland 21.93%
    Cedarleaf 19.78%
    Parsley 19.13%
    Heather 19.0%
    Broom 18.77%
    Genet 18.52%
    Lovage 18.51%
    Sweet-like 17.95%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.2

    pKa est.
    8.04 (weak base)

    Molecular weight
    422.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    843°C

    Melting point expt.

    • 148 - 150 °C

    Flash point

    • 256.21 ˚C est.

  • Synonyms

    • CYCLOMAMMEISIN
    • 1,2-Dihydro-5-hydroxy-2-(1-hydroxy-1-methylethyl)-4-(3-methylbutyryl)-6-phenylfurano[2,3-h][1]benzopyran-8-one
    • mammea A/AA cyclo F
    • CHEMBL451992
    • SCHEMBL30436103
    • CHEBI:175373
    • DTXSID901106232
    • LMPK12100013
    • 30563-62-3
    • 8,9-Dihydro-5-hydroxy-8-(1-hydroxy-1-methylethyl)-6-(3-methyl-1-oxobutyl)-4-phenyl-2H-furo[2,3-h]-1-benzopyran-2-one
    • 5-hydroxy-8-(2-hydroxypropan-2-yl)-6-(3-methylbutanoyl)-4-phenyl-8,9-dihydrouro[2,3-h]chromen-2-one
    • 8,9-Dihydro-5-hydroxy-8-(1-hydroxy-1-methylethyl)-6-(3-methyl-1-oxobutyl)-4-phenyl-2H-furo[2,3-h]-1-benzopyran-2-one, 9CI
    • 8,9-Dihydro-5-hydroxy-8-(1-hydroxy-1-methylethyl)-6-isovaleryl-4-phenyl-2H-furo[2,3-h]-1-benzopyran-2-one, 8CI
    • 8,9-dihydro-5-hydroxy-8-(2-hydroxypropan-2-yl)-6-(3-methylbutanoyl)-4-phenylfuro[2,3-h]chromen-2-one
    • 30563-62-3

  • Applications

    Cyclomammeisin (CAS 30563-62-3) is a fragrance-relevant sesquiterpene encountered in essential oil–derived formulations; in industry it is commonly evaluated as an odorant and fragrance ingredient for perfumery and cosmetics, where it may contribute distinctive aroma notes and can function as a mild fixative or modifier. It may also be used as an intermediate or building block in fragrance chemistry and related industrial manufacturing. Its applications may extend to household products as a scent additive, and it may be evaluated for flavor/aroma formulations in food processing where permitted by regulations, subject to local formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 42.32
    methanol 60.53
    isopropanol 26.58
    water 0.1
    ethyl acetate 42.67
    n-propanol 39.58
    acetone 101.97
    n-butanol 30.1
    acetonitrile 36.56
    DMF 389.38
    toluene 12.65
    isobutanol 28.94
    1,4-dioxane 58.35
    methyl acetate 68.01
    THF 187.95
    2-butanone 96.39
    n-pentanol 23.13
    sec-butanol 27.1
    n-hexane 0.31
    ethylene glycol 30.1
    NMP 439.7
    cyclohexane 0.52
    DMSO 290.18
    n-butyl acetate 38.5
    n-octanol 8.46
    chloroform 173.45
    n-propyl acetate 37.43
    acetic acid 241.25
    dichloromethane 143.5
    cyclohexanone 135.74
    propylene glycol 54.28
    isopropyl acetate 30.07
    DMAc 406.21
    2-ethoxyethanol 73.3
    isopentanol 27.87
    n-heptane 0.26
    ethyl formate 51.04
    1,2-dichloroethane 85.22
    n-hexanol 17.43
    2-methoxyethanol 159.33
    isobutyl acetate 28.84
    tetrachloromethane 8.81
    n-pentyl acetate 32.05
    transcutol 182.74
    n-heptanol 12.59
    ethylbenzene 5.66
    MIBK 37.28
    2-propoxyethanol 101.55
    tert-butanol 23.29
    MTBE 13.31
    2-butoxyethanol 59.91
    propionic acid 89.8
    o-xylene 7.41
    formic acid 111.26
    diethyl ether 12.72
    m-xylene 8.13
    p-xylene 8.87
    chlorobenzene 31.98
    dimethyl carbonate 72.65
    n-octane 0.15
    formamide 130.28
    cyclopentanone 224.76
    2-pentanone 60.23
    anisole 23.32
    cyclopentyl methyl ether 40.92
    gamma-butyrolactone 269.84
    1-methoxy-2-propanol 121.79
    pyridine 92.46
    3-pentanone 43.49
    furfural 200.71
    n-dodecane 0.22
    diethylene glycol 97.8
    diisopropyl ether 3.09
    tert-amyl alcohol 24.41
    acetylacetone 88.62
    n-hexadecane 0.26
    acetophenone 47.18
    methyl propionate 72.0
    isopentyl acetate 38.99
    trichloroethylene 269.86
    n-nonanol 9.06
    cyclohexanol 28.64
    benzyl alcohol 42.93
    2-ethylhexanol 11.1
    isooctanol 11.54
    dipropyl ether 9.11
    1,2-dichlorobenzene 32.67
    ethyl lactate 45.36
    propylene carbonate 137.66
    n-methylformamide 167.08
    2-pentanol 15.77
    n-pentane 0.33
    1-propoxy-2-propanol 62.55
    1-methoxy-2-propyl acetate 70.19
    2-(2-methoxypropoxy) propanol 65.56
    mesitylene 3.89
    ε-caprolactone 138.55
    p-cymene 5.18
    epichlorohydrin 273.5
    1,1,1-trichloroethane 55.65
    2-aminoethanol 51.83
    morpholine-4-carbaldehyde 300.81
    sulfolane 395.92
    2,2,4-trimethylpentane 0.44
    2-methyltetrahydrofuran 68.91
    n-hexyl acetate 32.93
    isooctane 0.25
    2-(2-butoxyethoxy)ethanol 78.23
    sec-butyl acetate 24.02
    tert-butyl acetate 32.7
    decalin 0.53
    glycerin 110.9
    diglyme 124.83
    acrylic acid 129.44
    isopropyl myristate 11.53
    n-butyric acid 96.77
    acetyl acetate 39.39
    di(2-ethylhexyl) phthalate 26.16
    ethyl propionate 32.82
    nitromethane 281.63
    1,2-diethoxyethane 29.38
    benzonitrile 43.67
    trioctyl phosphate 16.92
    1-bromopropane 24.02
    gamma-valerolactone 349.84
    n-decanol 6.27
    triethyl phosphate 21.86
    4-methyl-2-pentanol 10.99
    propionitrile 38.07
    vinylene carbonate 134.31
    1,1,2-trichlorotrifluoroethane 294.0
    DMS 56.51
    cumene 4.43
    2-octanol 6.87
    2-hexanone 42.48
    octyl acetate 18.15
    limonene 6.49
    1,2-dimethoxyethane 85.81
    ethyl orthosilicate 18.08
    tributyl phosphate 21.08
    diacetone alcohol 71.13
    N,N-dimethylaniline 20.49
    acrylonitrile 69.7
    aniline 38.78
    1,3-propanediol 64.58
    bromobenzene 26.14
    dibromomethane 62.4
    1,1,2,2-tetrachloroethane 183.6
    2-methyl-cyclohexyl acetate 32.0
    tetrabutyl urea 31.07
    diisobutyl methanol 6.36
    2-phenylethanol 42.62
    styrene 7.43
    dioctyl adipate 26.92
    dimethyl sulfate 152.24
    ethyl butyrate 28.03
    methyl lactate 102.66
    butyl lactate 48.34
    diethyl carbonate 22.15
    propanediol butyl ether 65.72
    triethyl orthoformate 23.42
    p-tert-butyltoluene 4.69
    methyl 4-tert-butylbenzoate 51.98
    morpholine 105.51
    tert-butylamine 7.53
    n-dodecanol 4.4
    dimethoxymethane 129.67
    ethylene carbonate 98.48
    cyrene 100.56
    2-ethoxyethyl acetate 61.24
    2-ethylhexyl acetate 28.79
    1,2,4-trichlorobenzene 58.66
    4-methylpyridine 85.61
    dibutyl ether 6.53
    2,6-dimethyl-4-heptanol 6.36
    DEF 90.33
    dimethyl isosorbide 113.91
    tetrachloroethylene 86.01
    eugenol 59.6
    triacetin 60.81
    span 80 52.69
    1,4-butanediol 26.46
    1,1-dichloroethane 66.68
    2-methyl-1-pentanol 23.73
    methyl formate 137.21
    2-methyl-1-butanol 30.12
    n-decane 0.34
    butyronitrile 34.43
    3,7-dimethyl-1-octanol 10.03
    1-chlorooctane 3.18
    1-chlorotetradecane 1.3
    n-nonane 0.26
    undecane 0.27
    tert-butylcyclohexane 0.47
    cyclooctane 0.18
    cyclopentanol 46.4
    tetrahydropyran 39.42
    tert-amyl methyl ether 13.5
    2,5,8-trioxanonane 87.64
    1-hexene 2.56
    2-isopropoxyethanol 47.59
    2,2,2-trifluoroethanol 91.86
    methyl butyrate 50.22

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction