Cyclohexyl propionate

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  • Identifiers

    CAS number
    6222-35-1

    Molecular formula
    C9H16O2

    SMILES
    CCC(=O)OC1CCCCC1

  • Odor profile

    Fragrance
    Fruity 97.03%
    Sweet 79.15%
    Pineapple 61.96%
    Banana 60.87%
    Apple 57.82%
    Green 51.33%
    Tropical 41.7%
    Ethereal 40.86%
    Apricot 40.85%
    Floral 37.57%

     

    Flavor
    Fruity 81.04%
    Pineapple 53.3%
    Fruit 49.98%
    Sweet 40.42%
    Berry 39.23%
    Tropical 37.71%
    Apple 32.0%
    Green 30.11%
    Rose 27.02%
    Raspberry 26.87%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.4

    pKa est.
    7.98 (neutral)

    Molecular weight
    156.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately fast

    Boiling point est.
    197°C

    Flash point

    • 80.4 ˚C est.

    Solubility expt.

    • insoluble in water
    • Miscible at room temperature (in ethanol)

  • Synonyms

    • CYCLOHEXYL PROPIONATE
    • 6222-35-1
    • Cyclohexyl propanoate
    • Propionic acid cyclohexyl ester
    • Propanoic acid, cyclohexyl ester
    • Propionic acid, cyclohexyl ester
    • cyclohexylpropionate
    • Cyclohexyl n-propionate
    • FEMA No. 2354
    • AI3-17708
    • UNII-7697L79NDU
    • 7697L79NDU
    • EINECS 228-303-5
    • NSC-11770
    • DTXSID20211277
    • CYCLOHEXYL PROPIONATE [FHFI]
    • NSC 11770
    • MFCD00046352
    • starbld0016573
    • SCHEMBL183236
    • Cyclohexyl propionate, >=99%
    • FEMA 2354
    • DTXCID20133768
    • CHEBI:171769
    • GAA22235
    • NSC11770
    • AKOS015961893
    • BS-23511
    • DB-054097
    • NS00022527
    • P0504
    • D91966
    • Q27266471
    • 228-303-5

  • Applications

    Cyclohexyl propionate (CAS 6222-35-1) is an ester commonly used as a fragrance ingredient in perfumery and cosmetics, contributing a light floral note to formulations. It may be employed as a flavor/aroma compound in food processing formulations or as a fragrance component in household cleaning products. It can function as a solvent or co-solvent in industrial manufacturing and in coatings, inks, and adhesives formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1915.08
    methanol 2160.4
    isopropanol 1832.41
    water 1.64
    ethyl acetate 1237.54
    n-propanol 1547.92
    acetone 2080.39
    n-butanol 1401.94
    acetonitrile 2003.53
    DMF 2105.92
    toluene 739.5
    isobutanol 1275.05
    1,4-dioxane 1724.89
    methyl acetate 1116.55
    THF 2098.75
    2-butanone 1471.65
    n-pentanol 1000.76
    sec-butanol 1527.85
    n-hexane 292.39
    ethylene glycol 255.76
    NMP 1678.41
    cyclohexane 422.22
    DMSO 1834.54
    n-butyl acetate 1341.89
    n-octanol 743.33
    chloroform 6556.64
    n-propyl acetate 918.99
    acetic acid 1836.92
    dichloromethane 4908.04
    cyclohexanone 2285.22
    propylene glycol 459.71
    isopropyl acetate 798.8
    DMAc 1395.92
    2-ethoxyethanol 869.45
    isopentanol 1188.69
    n-heptane 169.37
    ethyl formate 1143.18
    1,2-dichloroethane 2305.12
    n-hexanol 1086.99
    2-methoxyethanol 1387.6
    isobutyl acetate 584.84
    tetrachloromethane 818.21
    n-pentyl acetate 894.59
    transcutol 2310.1
    n-heptanol 574.67
    ethylbenzene 507.2
    MIBK 685.6
    2-propoxyethanol 1126.06
    tert-butanol 1763.69
    MTBE 1168.14
    2-butoxyethanol 804.38
    propionic acid 1417.61
    o-xylene 483.94
    formic acid 423.4
    diethyl ether 947.11
    m-xylene 467.16
    p-xylene 715.73
    chlorobenzene 1586.66
    dimethyl carbonate 363.78
    n-octane 96.09
    formamide 586.35
    cyclopentanone 2252.79
    2-pentanone 1149.23
    anisole 857.23
    cyclopentyl methyl ether 955.45
    gamma-butyrolactone 2603.48
    1-methoxy-2-propanol 1064.86
    pyridine 2370.85
    3-pentanone 771.61
    furfural 2266.91
    n-dodecane 87.75
    diethylene glycol 675.7
    diisopropyl ether 325.92
    tert-amyl alcohol 1345.62
    acetylacetone 1144.74
    n-hexadecane 99.22
    acetophenone 870.3
    methyl propionate 837.3
    isopentyl acetate 1118.58
    trichloroethylene 4905.43
    n-nonanol 585.12
    cyclohexanol 1333.61
    benzyl alcohol 783.75
    2-ethylhexanol 638.55
    isooctanol 465.48
    dipropyl ether 629.78
    1,2-dichlorobenzene 1322.52
    ethyl lactate 409.81
    propylene carbonate 1640.82
    n-methylformamide 1216.06
    2-pentanol 1006.41
    n-pentane 233.38
    1-propoxy-2-propanol 916.8
    1-methoxy-2-propyl acetate 773.16
    2-(2-methoxypropoxy) propanol 651.79
    mesitylene 318.12
    ε-caprolactone 1914.73
    p-cymene 330.96
    epichlorohydrin 2384.88
    1,1,1-trichloroethane 2491.27
    2-aminoethanol 644.14
    morpholine-4-carbaldehyde 1500.73
    sulfolane 2464.57
    2,2,4-trimethylpentane 119.14
    2-methyltetrahydrofuran 1729.06
    n-hexyl acetate 1261.01
    isooctane 95.4
    2-(2-butoxyethoxy)ethanol 895.02
    sec-butyl acetate 588.79
    tert-butyl acetate 730.45
    decalin 189.03
    glycerin 509.87
    diglyme 1541.77
    acrylic acid 1175.87
    isopropyl myristate 457.25
    n-butyric acid 1951.81
    acetyl acetate 848.57
    di(2-ethylhexyl) phthalate 395.53
    ethyl propionate 716.94
    nitromethane 2217.36
    1,2-diethoxyethane 930.84
    benzonitrile 1696.74
    trioctyl phosphate 310.12
    1-bromopropane 1677.57
    gamma-valerolactone 2345.95
    n-decanol 405.18
    triethyl phosphate 342.23
    4-methyl-2-pentanol 522.3
    propionitrile 1643.79
    vinylene carbonate 1587.22
    1,1,2-trichlorotrifluoroethane 1636.22
    DMS 672.72
    cumene 352.89
    2-octanol 499.43
    2-hexanone 975.37
    octyl acetate 583.14
    limonene 474.85
    1,2-dimethoxyethane 1550.49
    ethyl orthosilicate 316.44
    tributyl phosphate 401.05
    diacetone alcohol 781.05
    N,N-dimethylaniline 562.9
    acrylonitrile 1939.87
    aniline 1004.68
    1,3-propanediol 942.59
    bromobenzene 1823.09
    dibromomethane 3485.3
    1,1,2,2-tetrachloroethane 3787.75
    2-methyl-cyclohexyl acetate 584.76
    tetrabutyl urea 472.29
    diisobutyl methanol 385.11
    2-phenylethanol 729.97
    styrene 750.96
    dioctyl adipate 619.99
    dimethyl sulfate 566.17
    ethyl butyrate 817.72
    methyl lactate 467.33
    butyl lactate 654.01
    diethyl carbonate 569.91
    propanediol butyl ether 829.65
    triethyl orthoformate 506.38
    p-tert-butyltoluene 307.2
    methyl 4-tert-butylbenzoate 695.94
    morpholine 1919.75
    tert-butylamine 1254.07
    n-dodecanol 302.51
    dimethoxymethane 837.47
    ethylene carbonate 1324.27
    cyrene 509.51
    2-ethoxyethyl acetate 815.76
    2-ethylhexyl acetate 807.17
    1,2,4-trichlorobenzene 1407.64
    4-methylpyridine 2238.93
    dibutyl ether 826.48
    2,6-dimethyl-4-heptanol 385.11
    DEF 1213.26
    dimethyl isosorbide 915.78
    tetrachloroethylene 2383.87
    eugenol 693.13
    triacetin 863.39
    span 80 725.41
    1,4-butanediol 440.95
    1,1-dichloroethane 3007.55
    2-methyl-1-pentanol 865.01
    methyl formate 892.04
    2-methyl-1-butanol 1089.91
    n-decane 149.55
    butyronitrile 1933.67
    3,7-dimethyl-1-octanol 663.67
    1-chlorooctane 570.03
    1-chlorotetradecane 210.51
    n-nonane 154.27
    undecane 109.96
    tert-butylcyclohexane 171.86
    cyclooctane 118.9
    cyclopentanol 1446.92
    tetrahydropyran 1857.99
    tert-amyl methyl ether 734.14
    2,5,8-trioxanonane 1000.64
    1-hexene 892.22
    2-isopropoxyethanol 637.53
    2,2,2-trifluoroethanol 462.68
    methyl butyrate 1169.35

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction