Cyclohexanol, (2,2,3-trimethylnorbornanyl)-(mixed isomers)

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  • Identifiers

    CAS number
    80748-58-9

    Molecular formula
    C16H28O

    SMILES
    CC1C2CCC(C2)(C1(C)C)C3(CCCCC3)O

  • Odor profile

    Fragrance
    Woody 85.89%
    Sweet 57.18%
    Amber 54.3%
    Sandalwood 50.88%
    Balsamic 49.22%
    Dry 48.85%
    Cedar 43.43%
    Musk 43.22%
    Earthy 41.91%
    Clean 38.47%

     

    Flavor
    Earthy 49.86%
    Woody 48.31%
    Camphor 41.07%
    Sweet 40.61%
    Earth 37.03%
    Pine 36.98%
    Dry 33.95%
    Fresh 32.18%
    Herbal 31.75%
    Balsam 31.59%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    4.3

    pKa est.
    8.14 (weak base)

    Molecular weight
    236.39 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    333°C

    Flash point

    • 127.13 ˚C est.

  • Synonyms

    • Indisan
    • 80748-58-9
    • SCHEMBL7524727
    • JMLPIRYUSKIOGR-UHFFFAOYSA-N
    • DTXSID301001454
    • Cyclohexanol, (2,2,3-trimethylnorbornanyl)-(mixed isomers)
    • 1-(2,2,3-Trimethylbicyclo[2.2.1]heptan-1-yl)cyclohexan-1-ol

  • Applications

    Cyclohexanol, (2,2,3-trimethylnorbornanyl)-(mixed isomers) (CAS 80748-58-9) is primarily used as an intermediate in fragrance chemistry and as a stereochemically rich building block for organic synthesis. In perfumery and cosmetics, it functions as a fragrance ingredient and a small-molecule fixative to help stabilize complex scent profiles. In household products such as cleaners and air fresheners, it may serve as an odor-active component or aroma precursor in formulation. In polymers, plastics, coatings, and inks, it can be used as a chiral building block for aroma-related monomers or as a specialty additive to impart scent or modify material properties. In industrial manufacturing, it supports synthesis pathways for aroma-related chemicals, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 578.55
    methanol 568.16
    isopropanol 839.83
    water 4.73
    ethyl acetate 629.24
    n-propanol 655.16
    acetone 1011.17
    n-butanol 643.74
    acetonitrile 818.65
    DMF 1221.24
    toluene 761.63
    isobutanol 545.95
    1,4-dioxane 1636.73
    methyl acetate 613.96
    THF 2887.66
    2-butanone 724.27
    n-pentanol 274.06
    sec-butanol 453.94
    n-hexane 82.92
    ethylene glycol 94.71
    NMP 657.68
    cyclohexane 238.49
    DMSO 505.36
    n-butyl acetate 589.01
    n-octanol 260.04
    chloroform 1885.06
    n-propyl acetate 384.73
    acetic acid 292.7
    dichloromethane 1311.25
    cyclohexanone 1182.24
    propylene glycol 159.45
    isopropyl acetate 579.38
    DMAc 589.07
    2-ethoxyethanol 344.19
    isopentanol 530.79
    n-heptane 98.03
    ethyl formate 490.71
    1,2-dichloroethane 802.97
    n-hexanol 476.41
    2-methoxyethanol 709.56
    isobutyl acetate 356.43
    tetrachloromethane 487.42
    n-pentyl acetate 438.7
    transcutol 722.39
    n-heptanol 279.46
    ethylbenzene 323.64
    MIBK 554.46
    2-propoxyethanol 742.28
    tert-butanol 772.57
    MTBE 734.25
    2-butoxyethanol 459.22
    propionic acid 326.69
    o-xylene 408.72
    formic acid 102.49
    diethyl ether 777.19
    m-xylene 530.88
    p-xylene 463.5
    chlorobenzene 699.42
    dimethyl carbonate 343.11
    n-octane 46.36
    formamide 223.06
    cyclopentanone 1560.16
    2-pentanone 682.56
    anisole 501.65
    cyclopentyl methyl ether 913.93
    gamma-butyrolactone 1421.93
    1-methoxy-2-propanol 704.57
    pyridine 1152.34
    3-pentanone 469.17
    furfural 943.65
    n-dodecane 32.54
    diethylene glycol 402.12
    diisopropyl ether 315.39
    tert-amyl alcohol 387.83
    acetylacetone 753.46
    n-hexadecane 39.46
    acetophenone 416.08
    methyl propionate 485.14
    isopentyl acetate 579.31
    trichloroethylene 1314.21
    n-nonanol 229.25
    cyclohexanol 554.61
    benzyl alcohol 358.72
    2-ethylhexanol 265.19
    isooctanol 241.7
    dipropyl ether 440.88
    1,2-dichlorobenzene 591.44
    ethyl lactate 203.65
    propylene carbonate 703.35
    n-methylformamide 618.18
    2-pentanol 429.64
    n-pentane 133.45
    1-propoxy-2-propanol 565.97
    1-methoxy-2-propyl acetate 593.86
    2-(2-methoxypropoxy) propanol 305.93
    mesitylene 388.32
    ε-caprolactone 851.88
    p-cymene 242.63
    epichlorohydrin 1275.55
    1,1,1-trichloroethane 988.76
    2-aminoethanol 241.57
    morpholine-4-carbaldehyde 844.58
    sulfolane 987.1
    2,2,4-trimethylpentane 63.89
    2-methyltetrahydrofuran 1226.65
    n-hexyl acetate 509.02
    isooctane 77.13
    2-(2-butoxyethoxy)ethanol 410.81
    sec-butyl acetate 312.37
    tert-butyl acetate 602.37
    decalin 93.37
    glycerin 197.87
    diglyme 854.78
    acrylic acid 263.28
    isopropyl myristate 227.17
    n-butyric acid 575.37
    acetyl acetate 448.83
    di(2-ethylhexyl) phthalate 187.31
    ethyl propionate 367.16
    nitromethane 700.16
    1,2-diethoxyethane 516.06
    benzonitrile 642.47
    trioctyl phosphate 162.8
    1-bromopropane 598.7
    gamma-valerolactone 1530.45
    n-decanol 165.09
    triethyl phosphate 191.95
    4-methyl-2-pentanol 296.48
    propionitrile 887.12
    vinylene carbonate 726.95
    1,1,2-trichlorotrifluoroethane 556.01
    DMS 394.61
    cumene 238.79
    2-octanol 214.69
    2-hexanone 391.29
    octyl acetate 256.84
    limonene 274.52
    1,2-dimethoxyethane 861.01
    ethyl orthosilicate 194.7
    tributyl phosphate 176.19
    diacetone alcohol 485.35
    N,N-dimethylaniline 341.82
    acrylonitrile 905.52
    aniline 604.75
    1,3-propanediol 436.6
    bromobenzene 793.12
    dibromomethane 887.76
    1,1,2,2-tetrachloroethane 1023.31
    2-methyl-cyclohexyl acetate 325.11
    tetrabutyl urea 213.02
    diisobutyl methanol 223.23
    2-phenylethanol 447.61
    styrene 363.34
    dioctyl adipate 249.78
    dimethyl sulfate 387.17
    ethyl butyrate 406.29
    methyl lactate 273.57
    butyl lactate 310.66
    diethyl carbonate 268.91
    propanediol butyl ether 316.38
    triethyl orthoformate 310.13
    p-tert-butyltoluene 257.12
    methyl 4-tert-butylbenzoate 436.98
    morpholine 1433.99
    tert-butylamine 561.03
    n-dodecanol 122.93
    dimethoxymethane 1009.68
    ethylene carbonate 668.09
    cyrene 295.29
    2-ethoxyethyl acetate 496.62
    2-ethylhexyl acetate 439.32
    1,2,4-trichlorobenzene 609.84
    4-methylpyridine 1074.38
    dibutyl ether 318.99
    2,6-dimethyl-4-heptanol 223.23
    DEF 515.75
    dimethyl isosorbide 616.21
    tetrachloroethylene 758.94
    eugenol 358.67
    triacetin 385.83
    span 80 293.41
    1,4-butanediol 136.06
    1,1-dichloroethane 937.08
    2-methyl-1-pentanol 222.78
    methyl formate 511.22
    2-methyl-1-butanol 400.44
    n-decane 63.91
    butyronitrile 914.53
    3,7-dimethyl-1-octanol 243.88
    1-chlorooctane 202.26
    1-chlorotetradecane 80.0
    n-nonane 59.54
    undecane 44.54
    tert-butylcyclohexane 85.73
    cyclooctane 94.33
    cyclopentanol 642.19
    tetrahydropyran 1492.95
    tert-amyl methyl ether 377.31
    2,5,8-trioxanonane 482.47
    1-hexene 233.02
    2-isopropoxyethanol 277.82
    2,2,2-trifluoroethanol 193.97
    methyl butyrate 457.68

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction