Cyclohexadecane

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  • Identifiers

    CAS number
    295-65-8

    Molecular formula
    C16H32

    SMILES
    C1CCCCCCCCCCCCCCC1

    Safety labels

  • Odor profile

    Fragrance
    Sweet 64.39%
    Musk 52.24%
    Dry 41.24%
    Amber 36.16%
    Woody 31.14%
    Animal 26.21%
    Waxy 21.06%
    Powdery 19.67%
    Clean 16.82%
    Cedar 16.56%

     

    Flavor
    Animal 28.65%
    Alkane 22.06%
    Ammoniacal 20.95%
    Shrimp 19.48%
    Alkaline 19.29%
    Rotten 18.04%
    Beet 17.79%
    Tar 17.59%
    Soil 17.48%
    Tarry 17.48%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    8.9

    pKa est.
    11.12 (strong base)

    Molecular weight
    224.42 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    323°C

    Flash point

    • 139.25 ˚C est.

  • Synonyms

    • Cyclohexadecane
    • 295-65-8
    • EINECS 206-041-2
    • DTXSID40183700
    • RefChem:129524
    • DTXCID40106191
    • 206-041-2
    • InChI=1/C16H32/c1-2-4-6-8-10-12-14-16-15-13-11-9-7-5-3-1/h1-16H
    • JJWIOXUMXIOXQN-UHFFFAOYSA-N
    • SCHEMBL173428
    • SCHEMBL303616
    • SCHEMBL2231137
    • SCHEMBL2233947
    • SCHEMBL4350686
    • SCHEMBL4353045
    • SCHEMBL4355001
    • SCHEMBL4357254
    • SCHEMBL4361508
    • SCHEMBL4363314
    • SCHEMBL6519428
    • NS00041689
    • Q17992508
    • 295-65-8

  • Applications

    Cyclohexadecane (CAS 295-65-8) is a saturated cyclic alkane with 16 carbon atoms, used as a non-polar solvent and diluent in many industrial formulations. Real-world applications include: serving as a solvent and diluent for coatings, inks, adhesives, and polishes; acting as a carrier solvent/emollient in cosmetics and personal care products; serving as a processing solvent and diluent in polymer and plastics manufacturing; functioning as a solvent vehicle for fragrances and flavor-related components in the fragrance industry; and used as a non-polar cleaning solvent in industrial cleaning and degreasing operations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 60.88
    methanol 28.0
    isopropanol 95.36
    water 0.01
    ethyl acetate 911.44
    n-propanol 119.61
    acetone 459.62
    n-butanol 185.88
    acetonitrile 119.39
    DMF 411.55
    toluene 1020.53
    isobutanol 141.89
    1,4-dioxane 1104.92
    methyl acetate 421.05
    THF 2655.76
    2-butanone 618.95
    n-pentanol 134.61
    sec-butanol 177.28
    n-hexane 781.91
    ethylene glycol 5.65
    NMP 995.74
    cyclohexane 2267.93
    DMSO 406.56
    n-butyl acetate 1632.86
    n-octanol 209.79
    chloroform 1748.3
    n-propyl acetate 771.1
    acetic acid 112.73
    dichloromethane 1577.58
    cyclohexanone 1752.21
    propylene glycol 18.17
    isopropyl acetate 928.34
    DMAc 561.18
    2-ethoxyethanol 149.57
    isopentanol 260.68
    n-heptane 1772.94
    ethyl formate 246.41
    1,2-dichloroethane 1266.43
    n-hexanol 332.06
    2-methoxyethanol 177.63
    isobutyl acetate 665.67
    tetrachloromethane 628.97
    n-pentyl acetate 845.6
    transcutol 1141.49
    n-heptanol 216.15
    ethylbenzene 541.47
    MIBK 759.17
    2-propoxyethanol 377.54
    tert-butanol 268.32
    MTBE 893.5
    2-butoxyethanol 305.63
    propionic acid 162.8
    o-xylene 683.7
    formic acid 9.14
    diethyl ether 1104.01
    m-xylene 657.83
    p-xylene 676.38
    chlorobenzene 876.85
    dimethyl carbonate 213.7
    n-octane 415.41
    formamide 19.89
    cyclopentanone 1791.24
    2-pentanone 853.28
    anisole 634.48
    cyclopentyl methyl ether 2045.05
    gamma-butyrolactone 1454.71
    1-methoxy-2-propanol 249.5
    pyridine 1132.38
    3-pentanone 864.79
    furfural 886.49
    n-dodecane 146.87
    diethylene glycol 99.33
    diisopropyl ether 777.53
    tert-amyl alcohol 314.27
    acetylacetone 937.75
    n-hexadecane 187.17
    acetophenone 580.32
    methyl propionate 561.45
    isopentyl acetate 1431.14
    trichloroethylene 1906.1
    n-nonanol 234.5
    cyclohexanol 551.42
    benzyl alcohol 235.29
    2-ethylhexanol 598.4
    isooctanol 249.29
    dipropyl ether 2776.3
    1,2-dichlorobenzene 887.1
    ethyl lactate 206.61
    propylene carbonate 941.19
    n-methylformamide 93.8
    2-pentanol 261.12
    n-pentane 505.45
    1-propoxy-2-propanol 671.66
    1-methoxy-2-propyl acetate 1052.5
    2-(2-methoxypropoxy) propanol 375.65
    mesitylene 583.42
    ε-caprolactone 1274.79
    p-cymene 692.27
    epichlorohydrin 1386.72
    1,1,1-trichloroethane 1808.89
    2-aminoethanol 22.23
    morpholine-4-carbaldehyde 721.73
    sulfolane 1779.22
    2,2,4-trimethylpentane 262.05
    2-methyltetrahydrofuran 2060.03
    n-hexyl acetate 822.47
    isooctane 236.72
    2-(2-butoxyethoxy)ethanol 446.98
    sec-butyl acetate 780.68
    tert-butyl acetate 1202.51
    decalin 652.46
    glycerin 30.24
    diglyme 1195.46
    acrylic acid 109.7
    isopropyl myristate 548.44
    n-butyric acid 449.0
    acetyl acetate 632.65
    di(2-ethylhexyl) phthalate 239.15
    ethyl propionate 825.42
    nitromethane 241.56
    1,2-diethoxyethane 1422.06
    benzonitrile 426.05
    trioctyl phosphate 225.2
    1-bromopropane 1328.19
    gamma-valerolactone 1324.18
    n-decanol 177.81
    triethyl phosphate 656.33
    4-methyl-2-pentanol 222.22
    propionitrile 264.45
    vinylene carbonate 572.08
    1,1,2-trichlorotrifluoroethane 625.13
    DMS 494.56
    cumene 402.39
    2-octanol 203.41
    2-hexanone 703.16
    octyl acetate 490.57
    limonene 1384.19
    1,2-dimethoxyethane 817.6
    ethyl orthosilicate 693.48
    tributyl phosphate 326.92
    diacetone alcohol 608.05
    N,N-dimethylaniline 519.07
    acrylonitrile 218.32
    aniline 491.25
    1,3-propanediol 59.27
    bromobenzene 1288.03
    dibromomethane 1359.05
    1,1,2,2-tetrachloroethane 1893.6
    2-methyl-cyclohexyl acetate 996.65
    tetrabutyl urea 436.84
    diisobutyl methanol 640.24
    2-phenylethanol 331.17
    styrene 639.2
    dioctyl adipate 622.23
    dimethyl sulfate 373.55
    ethyl butyrate 1700.63
    methyl lactate 153.86
    butyl lactate 378.07
    diethyl carbonate 850.75
    propanediol butyl ether 163.94
    triethyl orthoformate 1333.67
    p-tert-butyltoluene 697.44
    methyl 4-tert-butylbenzoate 612.28
    morpholine 1038.74
    tert-butylamine 309.09
    n-dodecanol 156.4
    dimethoxymethane 484.8
    ethylene carbonate 627.04
    cyrene 333.31
    2-ethoxyethyl acetate 722.14
    2-ethylhexyl acetate 1387.91
    1,2,4-trichlorobenzene 952.65
    4-methylpyridine 1019.1
    dibutyl ether 1420.19
    2,6-dimethyl-4-heptanol 640.24
    DEF 998.92
    dimethyl isosorbide 1058.15
    tetrachloroethylene 1196.56
    eugenol 337.46
    triacetin 679.57
    span 80 407.6
    1,4-butanediol 21.94
    1,1-dichloroethane 1123.13
    2-methyl-1-pentanol 199.31
    methyl formate 95.49
    2-methyl-1-butanol 228.9
    n-decane 321.81
    butyronitrile 380.56
    3,7-dimethyl-1-octanol 353.26
    1-chlorooctane 610.13
    1-chlorotetradecane 267.82
    n-nonane 368.04
    undecane 200.83
    tert-butylcyclohexane 483.89
    cyclooctane 959.22
    cyclopentanol 441.83
    tetrahydropyran 2206.48
    tert-amyl methyl ether 898.98
    2,5,8-trioxanonane 742.36
    1-hexene 876.03
    2-isopropoxyethanol 187.86
    2,2,2-trifluoroethanol 49.51
    methyl butyrate 941.0

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction