Cyclododecoxazole, 4,5,6,7,8,9,10,11,12,13-decahydro-

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  • Identifiers

    CAS number
    38303-23-0

    Molecular formula
    C13H21NO

    SMILES
    C1CCCCCC2=C(CCCC1)N=CO2

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Green 69.64%
    Woody 65.44%
    Earthy 65.32%
    Herbal 62.78%
    Animal 44.5%
    Tobacco 36.82%
    Musty 36.43%
    Sweet 33.74%
    Nutty 30.1%
    Dry 28.17%

     

    Flavor
    Earthy 36.07%
    Animal 34.74%
    Musty 34.4%
    Roasted 33.36%
    Fruity 30.17%
    Cheese 26.12%
    Cereal 24.6%
    Shrimp 24.43%
    Nutty 23.57%
    Alkaline 23.4%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    4.7

    pKa est.
    8.81 (weak base)

    Molecular weight
    207.31 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    302°C

    Flash point

    • 134.75 ˚C est.

  • Synonyms

    • 38303-23-0
    • 4,5-decamethyleneoxazole
    • EINECS 253-869-5
    • Cyclododecoxazole, 4,5,6,7,8,9,10,11,12,13-decahydro-
    • 4,5,6,7,8,9,10,11,12,13-Decahydrocyclododecoxazole
    • DTXSID9068087
    • SCHEMBL717035
    • DTXCID6039475
    • LUVGCXAXOHXTEI-UHFFFAOYSA-N
    • NS00012179

  • Applications

    Cyclododecoxazole, 4,5,6,7,8,9,10,11,12,13-decahydro- (CAS 38303-23-0) may be used as an organic synthesis intermediate; it may function as a processing additive and stabilizer in polymer and plastic formulations, and can serve as a precursor in heterocyclic chemistry for pharmaceutical or agrochemical development; it may also be evaluated for use in coatings and inks as a functional additive, and can be explored for electronic materials applications as a small-molecule additive.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 774.81
    methanol 755.63
    isopropanol 697.8
    water 0.09
    ethyl acetate 1269.87
    n-propanol 884.75
    acetone 1775.72
    n-butanol 723.47
    acetonitrile 858.88
    DMF 2358.64
    toluene 1591.19
    isobutanol 728.21
    1,4-dioxane 1858.76
    methyl acetate 1096.37
    THF 3151.92
    2-butanone 1551.86
    n-pentanol 549.56
    sec-butanol 729.81
    n-hexane 219.7
    ethylene glycol 144.32
    NMP 2329.02
    cyclohexane 581.72
    DMSO 1955.64
    n-butyl acetate 1032.1
    n-octanol 328.63
    chloroform 5846.0
    n-propyl acetate 944.99
    acetic acid 886.61
    dichloromethane 5456.38
    cyclohexanone 3110.23
    propylene glycol 247.87
    isopropyl acetate 853.55
    DMAc 1543.79
    2-ethoxyethanol 617.64
    isopentanol 679.15
    n-heptane 154.08
    ethyl formate 959.61
    1,2-dichloroethane 3172.66
    n-hexanol 534.47
    2-methoxyethanol 970.03
    isobutyl acetate 711.61
    tetrachloromethane 930.62
    n-pentyl acetate 887.09
    transcutol 2044.12
    n-heptanol 323.59
    ethylbenzene 648.58
    MIBK 742.39
    2-propoxyethanol 711.38
    tert-butanol 627.85
    MTBE 810.18
    2-butoxyethanol 566.41
    propionic acid 922.32
    o-xylene 713.13
    formic acid 189.13
    diethyl ether 1041.87
    m-xylene 771.77
    p-xylene 790.12
    chlorobenzene 2027.75
    dimethyl carbonate 574.91
    n-octane 77.74
    formamide 352.1
    cyclopentanone 3392.07
    2-pentanone 1323.07
    anisole 887.86
    cyclopentyl methyl ether 1552.41
    gamma-butyrolactone 3159.28
    1-methoxy-2-propanol 760.91
    pyridine 3140.72
    3-pentanone 1161.25
    furfural 2336.65
    n-dodecane 57.13
    diethylene glycol 440.27
    diisopropyl ether 345.73
    tert-amyl alcohol 604.35
    acetylacetone 1298.99
    n-hexadecane 67.85
    acetophenone 898.13
    methyl propionate 1104.98
    isopentyl acetate 894.75
    trichloroethylene 5799.67
    n-nonanol 289.47
    cyclohexanol 1147.88
    benzyl alcohol 740.14
    2-ethylhexanol 392.16
    isooctanol 288.92
    dipropyl ether 577.12
    1,2-dichlorobenzene 1614.99
    ethyl lactate 341.58
    propylene carbonate 1716.24
    n-methylformamide 1071.58
    2-pentanol 549.76
    n-pentane 210.72
    1-propoxy-2-propanol 612.51
    1-methoxy-2-propyl acetate 750.7
    2-(2-methoxypropoxy) propanol 442.87
    mesitylene 447.11
    ε-caprolactone 2042.0
    p-cymene 321.66
    epichlorohydrin 2946.84
    1,1,1-trichloroethane 2594.91
    2-aminoethanol 338.41
    morpholine-4-carbaldehyde 1674.99
    sulfolane 3143.89
    2,2,4-trimethylpentane 103.98
    2-methyltetrahydrofuran 2200.54
    n-hexyl acetate 979.26
    isooctane 78.83
    2-(2-butoxyethoxy)ethanol 655.77
    sec-butyl acetate 624.07
    tert-butyl acetate 743.39
    decalin 215.04
    glycerin 319.72
    diglyme 1246.45
    acrylic acid 848.82
    isopropyl myristate 333.46
    n-butyric acid 1345.46
    acetyl acetate 795.85
    di(2-ethylhexyl) phthalate 318.78
    ethyl propionate 760.91
    nitromethane 1412.12
    1,2-diethoxyethane 948.77
    benzonitrile 1348.36
    trioctyl phosphate 233.03
    1-bromopropane 1820.66
    gamma-valerolactone 2809.62
    n-decanol 208.72
    triethyl phosphate 310.74
    4-methyl-2-pentanol 320.72
    propionitrile 1086.3
    vinylene carbonate 1548.35
    1,1,2-trichlorotrifluoroethane 1586.11
    DMS 763.19
    cumene 376.85
    2-octanol 271.4
    2-hexanone 900.42
    octyl acetate 411.03
    limonene 461.99
    1,2-dimethoxyethane 1261.56
    ethyl orthosilicate 303.23
    tributyl phosphate 308.87
    diacetone alcohol 595.13
    N,N-dimethylaniline 573.41
    acrylonitrile 1405.1
    aniline 1333.19
    1,3-propanediol 516.32
    bromobenzene 2477.25
    dibromomethane 3660.76
    1,1,2,2-tetrachloroethane 4136.47
    2-methyl-cyclohexyl acetate 542.13
    tetrabutyl urea 395.07
    diisobutyl methanol 253.74
    2-phenylethanol 595.03
    styrene 932.22
    dioctyl adipate 453.5
    dimethyl sulfate 908.81
    ethyl butyrate 678.86
    methyl lactate 439.25
    butyl lactate 533.79
    diethyl carbonate 476.85
    propanediol butyl ether 494.38
    triethyl orthoformate 467.26
    p-tert-butyltoluene 290.03
    methyl 4-tert-butylbenzoate 615.22
    morpholine 1957.05
    tert-butylamine 491.62
    n-dodecanol 164.63
    dimethoxymethane 1149.73
    ethylene carbonate 1423.05
    cyrene 530.5
    2-ethoxyethyl acetate 966.95
    2-ethylhexyl acetate 785.03
    1,2,4-trichlorobenzene 1795.07
    4-methylpyridine 2572.04
    dibutyl ether 621.57
    2,6-dimethyl-4-heptanol 253.74
    DEF 1426.8
    dimethyl isosorbide 821.54
    tetrachloroethylene 2921.03
    eugenol 539.53
    triacetin 720.62
    span 80 483.37
    1,4-butanediol 253.63
    1,1-dichloroethane 2747.2
    2-methyl-1-pentanol 522.13
    methyl formate 859.63
    2-methyl-1-butanol 675.03
    n-decane 95.86
    butyronitrile 1083.88
    3,7-dimethyl-1-octanol 322.93
    1-chlorooctane 389.73
    1-chlorotetradecane 151.7
    n-nonane 100.83
    undecane 69.9
    tert-butylcyclohexane 150.6
    cyclooctane 187.46
    cyclopentanol 1282.08
    tetrahydropyran 2438.23
    tert-amyl methyl ether 617.27
    2,5,8-trioxanonane 746.47
    1-hexene 651.78
    2-isopropoxyethanol 474.54
    2,2,2-trifluoroethanol 340.4
    methyl butyrate 1129.4

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction