Cyclododecane, (methoxymethoxy)-

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  • Identifiers

    CAS number
    42604-12-6

    Molecular formula
    C14H28O2

    SMILES
    COCOC1CCCCCCCCCCC1

  • Odor profile

    Fragrance
    Woody 85.83%
    Amber 69.54%
    Cedar 57.85%
    Dry 57.46%
    Musk 48.29%
    Vetiver 33.0%
    Natural 31.38%
    Camphoreous 30.76%
    Clean 29.77%
    Fresh 28.49%

     

    Flavor
    Fruity 43.61%
    Green 29.12%
    Fruit 27.79%
    Earthy 26.88%
    Pineapple 24.66%
    Rose 24.64%
    Plant 22.08%
    Shrimp 21.28%
    Beet 21.16%
    Musty 21.08%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    5.1

    pKa est.
    8.51 (weak base)

    Molecular weight
    228.37 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    295°C

    Flash point

    • 110.06 ˚C est.

  • Synonyms

    • (Methoxymethoxy)cyclododecane
    • 42604-12-6
    • Boisambrene
    • methoxymethoxycyclododecane
    • Cyclododecane, (methoxymethoxy)-
    • Formaldehyde cyclodecyl methyl acetal
    • Formaldehyde cyclododecyl methyl acetal
    • Methoxycyclodocecyloxymethane
    • EINECS 255-908-1
    • BRN 2432409
    • DTXSID4068408
    • ambrene acetal
    • MNA54SZ3RD
    • SCHEMBL3504567
    • DTXCID4040135
    • HPTIDIPGIUCQFC-UHFFFAOYSA-N
    • NS00012483
    • 255-908-1

  • Applications

    Chemical name Cyclododecane, (methoxymethoxy)-; CAS 42604-12-6 is a methoxymethyl ether derivative of cyclododecane, primarily used as an organic synthesis intermediate and as a MOM-protected form for subsequent transformations. In practical industry use, it is employed as a non-polar solvent or diluent and as a carrier for fragrance components in perfumery and cosmetics; as a solvent or carrier in household products and cleaners; as a processing aid in coatings, inks, and adhesives; as a diluent in polymers and plastics formulations; and as a specialty solvent in electronics manufacturing, depending on formulation needs and regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 754.66
    methanol 383.62
    isopropanol 1122.83
    water 0.04
    ethyl acetate 2938.6
    n-propanol 1151.78
    acetone 2481.35
    n-butanol 1182.91
    acetonitrile 1429.28
    DMF 1651.89
    toluene 2275.41
    isobutanol 1079.04
    1,4-dioxane 3203.22
    methyl acetate 1819.85
    THF 5372.65
    2-butanone 2231.35
    n-pentanol 739.79
    sec-butanol 1270.57
    n-hexane 818.73
    ethylene glycol 75.04
    NMP 2096.21
    cyclohexane 2733.53
    DMSO 2325.67
    n-butyl acetate 2560.49
    n-octanol 579.02
    chloroform 9271.15
    n-propyl acetate 2195.73
    acetic acid 1051.87
    dichloromethane 8399.56
    cyclohexanone 4963.48
    propylene glycol 220.04
    isopropyl acetate 2280.23
    DMAc 1312.58
    2-ethoxyethanol 887.47
    isopentanol 1206.6
    n-heptane 922.23
    ethyl formate 1372.86
    1,2-dichloroethane 5088.57
    n-hexanol 973.1
    2-methoxyethanol 1207.59
    isobutyl acetate 1347.66
    tetrachloromethane 2272.72
    n-pentyl acetate 1915.15
    transcutol 2862.62
    n-heptanol 592.78
    ethylbenzene 1091.26
    MIBK 1648.6
    2-propoxyethanol 1177.83
    tert-butanol 1648.52
    MTBE 2153.82
    2-butoxyethanol 1029.97
    propionic acid 1249.32
    o-xylene 1257.86
    formic acid 121.53
    diethyl ether 2415.99
    m-xylene 1344.63
    p-xylene 1339.38
    chlorobenzene 2780.0
    dimethyl carbonate 652.19
    n-octane 296.98
    formamide 262.63
    cyclopentanone 4753.28
    2-pentanone 2578.77
    anisole 1438.74
    cyclopentyl methyl ether 3437.43
    gamma-butyrolactone 4630.45
    1-methoxy-2-propanol 1297.98
    pyridine 3910.56
    3-pentanone 2010.47
    furfural 3162.27
    n-dodecane 139.97
    diethylene glycol 477.12
    diisopropyl ether 1133.12
    tert-amyl alcohol 1493.0
    acetylacetone 2390.46
    n-hexadecane 174.45
    acetophenone 1405.83
    methyl propionate 1766.63
    isopentyl acetate 2045.36
    trichloroethylene 8252.61
    n-nonanol 551.41
    cyclohexanol 2458.9
    benzyl alcohol 937.13
    2-ethylhexanol 949.14
    isooctanol 599.12
    dipropyl ether 2293.31
    1,2-dichlorobenzene 2642.26
    ethyl lactate 676.25
    propylene carbonate 2762.32
    n-methylformamide 797.35
    2-pentanol 1235.36
    n-pentane 747.69
    1-propoxy-2-propanol 1347.19
    1-methoxy-2-propyl acetate 1579.65
    2-(2-methoxypropoxy) propanol 711.61
    mesitylene 968.69
    ε-caprolactone 3708.38
    p-cymene 793.8
    epichlorohydrin 4839.32
    1,1,1-trichloroethane 5915.57
    2-aminoethanol 273.49
    morpholine-4-carbaldehyde 1979.37
    sulfolane 4865.99
    2,2,4-trimethylpentane 316.13
    2-methyltetrahydrofuran 4205.15
    n-hexyl acetate 1768.52
    isooctane 275.13
    2-(2-butoxyethoxy)ethanol 997.52
    sec-butyl acetate 1587.64
    tert-butyl acetate 2194.4
    decalin 648.39
    glycerin 265.2
    diglyme 2273.58
    acrylic acid 855.31
    isopropyl myristate 741.54
    n-butyric acid 2472.91
    acetyl acetate 1886.6
    di(2-ethylhexyl) phthalate 466.96
    ethyl propionate 1923.57
    nitromethane 1918.96
    1,2-diethoxyethane 2063.96
    benzonitrile 1788.81
    trioctyl phosphate 409.56
    1-bromopropane 3705.95
    gamma-valerolactone 4097.56
    n-decanol 395.39
    triethyl phosphate 784.3
    4-methyl-2-pentanol 730.75
    propionitrile 1740.57
    vinylene carbonate 2129.2
    1,1,2-trichlorotrifluoroethane 2644.34
    DMS 1063.53
    cumene 684.12
    2-octanol 543.27
    2-hexanone 1674.91
    octyl acetate 808.72
    limonene 1341.32
    1,2-dimethoxyethane 2190.11
    ethyl orthosilicate 758.16
    tributyl phosphate 535.53
    diacetone alcohol 1434.22
    N,N-dimethylaniline 888.99
    acrylonitrile 1754.71
    aniline 1847.4
    1,3-propanediol 539.24
    bromobenzene 3616.89
    dibromomethane 6124.1
    1,1,2,2-tetrachloroethane 7202.14
    2-methyl-cyclohexyl acetate 1234.24
    tetrabutyl urea 634.6
    diisobutyl methanol 763.14
    2-phenylethanol 828.57
    styrene 1441.87
    dioctyl adipate 973.38
    dimethyl sulfate 1043.42
    ethyl butyrate 2117.68
    methyl lactate 617.06
    butyl lactate 1012.01
    diethyl carbonate 1239.3
    propanediol butyl ether 696.01
    triethyl orthoformate 1399.98
    p-tert-butyltoluene 741.92
    methyl 4-tert-butylbenzoate 1110.94
    morpholine 3501.76
    tert-butylamine 1380.88
    n-dodecanol 309.48
    dimethoxymethane 1491.05
    ethylene carbonate 2239.81
    cyrene 727.29
    2-ethoxyethyl acetate 1620.69
    2-ethylhexyl acetate 1749.4
    1,2,4-trichlorobenzene 2782.0
    4-methylpyridine 3278.96
    dibutyl ether 1672.52
    2,6-dimethyl-4-heptanol 763.14
    DEF 2302.46
    dimethyl isosorbide 1476.8
    tetrachloroethylene 4834.91
    eugenol 751.81
    triacetin 1447.04
    span 80 852.11
    1,4-butanediol 225.54
    1,1-dichloroethane 5244.36
    2-methyl-1-pentanol 743.09
    methyl formate 693.85
    2-methyl-1-butanol 1100.3
    n-decane 299.26
    butyronitrile 1998.84
    3,7-dimethyl-1-octanol 723.05
    1-chlorooctane 936.66
    1-chlorotetradecane 337.19
    n-nonane 332.75
    undecane 190.28
    tert-butylcyclohexane 473.99
    cyclooctane 863.48
    cyclopentanol 2284.48
    tetrahydropyran 5078.05
    tert-amyl methyl ether 1683.47
    2,5,8-trioxanonane 1267.04
    1-hexene 1505.35
    2-isopropoxyethanol 775.97
    2,2,2-trifluoroethanol 432.13
    methyl butyrate 2576.04

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction