Cyclododecane

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  • Identifiers

    CAS number
    294-62-2

    Molecular formula
    C12H24

    SMILES
    C1CCCCCCCCCCC1

  • Odor profile

    Sweet 64.39%
    Musk 52.24%
    Dry 41.24%
    Amber 36.16%
    Woody 31.14%
    Animal 26.21%
    Waxy 21.06%
    Powdery 19.67%
    Clean 16.82%
    Cedar 16.56%

    Scent© AI

  • Properties

    XLogP3-AA
    6.7

    Molecular weight
    168.32 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Melting point expt.

    • 60.4 °C

    Boiling point

    • 247 °C

    Flash point est.
    80.08 ˚C

    Solubility expt.

    • Insoluble in water; very soluble in alcohol, ethyl ether

  • Synonyms

    • CYCLODODECANE
    • 294-62-2
    • Cyclododecan
    • EINECS 206-033-9
    • HSDB 5557
    • UNII-97CN13ZD83
    • BRN 1901008
    • DTXSID9021552
    • 97CN13ZD83
    • MFCD00014258
    • CYCLODODECANE [HSDB]
    • DTXCID401552
    • EC 206-033-9
    • 4-05-00-00169 (Beilstein Handbook Reference)
    • CHEMBL3185808
    • Tox21_202734
    • AKOS006227986
    • NCGC00260282-01
    • AS-56381
    • CAS-294-62-2
    • FC158937
    • SY053627
    • DB-047586
    • CS-0155296
    • NS00002938
    • D89269
    • Q118040
    • 206-033-9

  • Applications

    Cyclododecane (CAS 294-62-2) is a waxy cyclic hydrocarbon that sublimes, making it useful as a temporary consolidant/protective medium and as a sacrificial layer across applications: in cultural heritage conservation it temporarily consolidates porous substrates (stone, plaster, ceramics, wood, paper), acts as a moisture/dust barrier, binds loose pigments, and masks areas during treatment, then disappears with minimal residue; in analysis and sample preparation it provides transient mounting and edge support for thin specimens for SEM or micro-CT, stabilizes cracks for molding or sectioning, and seals voids in archaeological and geological samples for transport and imaging; in microfabrication and materials research it serves as a subliming sacrificial layer to form temporary masks, channels, and voids in soft lithography/PDMS molding, microfluidics, and surface processing; industrially it is an intermediate oxidized to cyclododecanol/cyclododecanone and converted to laurolactam for Nylon-12 production, and it also appears in certain polymer additive applications; in practice it is flammable and releases vapors as it sublimes (use ventilation), and it can typically be removed by allowing sublimation or rinsing with nonpolar solvents.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 136.52
    methanol 54.18
    isopropanol 214.99
    water 0.01
    ethyl acetate 698.69
    n-propanol 250.71
    acetone 545.9
    n-butanol 314.21
    acetonitrile 208.04
    DMF 550.4
    toluene 1048.04
    isobutanol 259.31
    1,4-dioxane 1157.1
    methyl acetate 489.38
    THF 2636.7
    2-butanone 671.74
    n-pentanol 215.02
    sec-butanol 303.53
    n-hexane 708.01
    ethylene glycol 17.13
    NMP 939.18
    cyclohexane 1828.97
    DMSO 572.34
    n-butyl acetate 1262.32
    n-octanol 284.69
    chloroform 2035.61
    n-propyl acetate 627.78
    acetic acid 172.26
    dichloromethane 1803.03
    cyclohexanone 1715.02
    propylene glycol 47.29
    isopropyl acetate 608.29
    DMAc 468.04
    2-ethoxyethanol 180.57
    isopentanol 322.9
    n-heptane 1709.75
    ethyl formate 330.49
    1,2-dichloroethane 1229.46
    n-hexanol 523.04
    2-methoxyethanol 239.36
    isobutyl acetate 482.21
    tetrachloromethane 638.71
    n-pentyl acetate 680.65
    transcutol 674.7
    n-heptanol 290.43
    ethylbenzene 527.44
    MIBK 535.52
    2-propoxyethanol 426.71
    tert-butanol 401.95
    MTBE 646.52
    2-butoxyethanol 318.56
    propionic acid 269.41
    o-xylene 597.26
    formic acid 12.87
    diethyl ether 846.62
    m-xylene 606.63
    p-xylene 664.74
    chlorobenzene 987.77
    dimethyl carbonate 200.05
    n-octane 430.85
    formamide 30.1
    cyclopentanone 1947.42
    2-pentanone 763.66
    anisole 541.83
    cyclopentyl methyl ether 1574.7
    gamma-butyrolactone 1707.93
    1-methoxy-2-propanol 299.08
    pyridine 1321.87
    3-pentanone 685.97
    furfural 939.44
    n-dodecane 182.09
    diethylene glycol 144.11
    diisopropyl ether 470.51
    tert-amyl alcohol 387.64
    acetylacetone 712.16
    n-hexadecane 218.03
    acetophenone 521.64
    methyl propionate 521.78
    isopentyl acetate 991.82
    trichloroethylene 1860.6
    n-nonanol 284.95
    cyclohexanol 686.32
    benzyl alcohol 291.3
    2-ethylhexanol 633.36
    isooctanol 280.33
    dipropyl ether 1917.7
    1,2-dichlorobenzene 869.84
    ethyl lactate 213.99
    propylene carbonate 1081.05
    n-methylformamide 149.64
    2-pentanol 340.02
    n-pentane 544.87
    1-propoxy-2-propanol 622.26
    1-methoxy-2-propyl acetate 691.09
    2-(2-methoxypropoxy) propanol 296.1
    mesitylene 458.67
    ε-caprolactone 1245.42
    p-cymene 584.87
    epichlorohydrin 1441.41
    1,1,1-trichloroethane 1576.32
    2-aminoethanol 49.13
    morpholine-4-carbaldehyde 647.62
    sulfolane 1856.28
    2,2,4-trimethylpentane 189.59
    2-methyltetrahydrofuran 1964.55
    n-hexyl acetate 705.5
    isooctane 185.36
    2-(2-butoxyethoxy)ethanol 402.07
    sec-butyl acetate 494.91
    tert-butyl acetate 692.24
    decalin 470.43
    glycerin 56.52
    diglyme 859.32
    acrylic acid 192.66
    isopropyl myristate 425.66
    n-butyric acid 551.37
    acetyl acetate 457.01
    di(2-ethylhexyl) phthalate 223.27
    ethyl propionate 593.92
    nitromethane 287.43
    1,2-diethoxyethane 843.84
    benzonitrile 570.27
    trioctyl phosphate 229.75
    1-bromopropane 1333.58
    gamma-valerolactone 1296.08
    n-decanol 219.48
    triethyl phosphate 460.44
    4-methyl-2-pentanol 230.3
    propionitrile 429.55
    vinylene carbonate 703.45
    1,1,2-trichlorotrifluoroethane 621.92
    DMS 386.18
    cumene 353.54
    2-octanol 263.29
    2-hexanone 618.86
    octyl acetate 419.78
    limonene 1080.15
    1,2-dimethoxyethane 704.03
    ethyl orthosilicate 449.38
    tributyl phosphate 292.63
    diacetone alcohol 449.34
    N,N-dimethylaniline 412.34
    acrylonitrile 374.76
    aniline 537.61
    1,3-propanediol 107.53
    bromobenzene 1352.62
    dibromomethane 1583.96
    1,1,2,2-tetrachloroethane 1696.12
    2-methyl-cyclohexyl acetate 710.5
    tetrabutyl urea 397.41
    diisobutyl methanol 537.38
    2-phenylethanol 357.61
    styrene 625.61
    dioctyl adipate 503.18
    dimethyl sulfate 313.51
    ethyl butyrate 1206.86
    methyl lactate 170.37
    butyl lactate 359.18
    diethyl carbonate 667.9
    propanediol butyl ether 194.21
    triethyl orthoformate 855.68
    p-tert-butyltoluene 563.32
    methyl 4-tert-butylbenzoate 474.81
    morpholine 1099.84
    tert-butylamine 390.03
    n-dodecanol 194.03
    dimethoxymethane 453.88
    ethylene carbonate 728.83
    cyrene 323.74
    2-ethoxyethyl acetate 455.49
    2-ethylhexyl acetate 937.4
    1,2,4-trichlorobenzene 862.93
    4-methylpyridine 1122.45
    dibutyl ether 1160.82
    2,6-dimethyl-4-heptanol 537.38
    DEF 725.99
    dimethyl isosorbide 805.21
    tetrachloroethylene 1109.35
    eugenol 305.4
    triacetin 499.94
    span 80 397.49
    1,4-butanediol 45.77
    1,1-dichloroethane 1212.79
    2-methyl-1-pentanol 230.6
    methyl formate 147.59
    2-methyl-1-butanol 300.65
    n-decane 347.87
    butyronitrile 550.63
    3,7-dimethyl-1-octanol 359.1
    1-chlorooctane 638.31
    1-chlorotetradecane 262.55
    n-nonane 418.94
    undecane 236.12
    tert-butylcyclohexane 346.0
    cyclooctane 794.45
    cyclopentanol 737.73
    tetrahydropyran 2095.47
    tert-amyl methyl ether 589.15
    2,5,8-trioxanonane 567.43
    1-hexene 885.94
    2-isopropoxyethanol 198.91
    2,2,2-trifluoroethanol 67.17
    methyl butyrate 769.13

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Amomum ptycholimatum Amomum ptycholimatum D. Fang, fam. Zingiberaceae 1.4%