Cyclodextrin glucanotransferase

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  • Identifiers

    CAS number
    9030-09-5

    Molecular formula
    C120H98Cl2F6N16O19

    SMILES
    C1CC2=C(C=CC=C2F)C(N3CN(CC=C1)C(=O)C4=C(C(=O)C=CN43)O)C5=NC(=CC=C5)F.C1C=CCOC2=C(C=CC=C2Cl)C(N3CN1C(=O)C4=C(C(=O)C=CN43)O)C5=CC=CC=C5.C1C=CCOC2=C(C=CC=C2Cl)C(N3CN1C(=O)C4=C(C(=O)C=CN43)O)C5=CC=CC=C5.C1C=CCOC2=C(C=CC(=C2F)F)C(N3CN1C(=O)C4=C(C(=O)C=CN43)O)C5=CC=CC=C5.C1C=CCOC2=C(C=CC(=C2F)F)C(N3CN1C(=O)C4=C(C(=O)C=CN43)O)C5=CC=CC=C5

    Safety labels

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 55.13%
    Bitter 24.63%
    Roasted 24.34%
    Burnt 23.26%
    Animal 22.05%
    Cooked 20.01%
    Savory 19.86%
    Meaty 18.81%
    Phenolic 17.38%
    Nutty 17.14%

     

    Flavor
    Bitter 92.31%
    Odorless 25.2%
    Very strong 20.09%
    Indole 19.85%
    Cedarleaf 19.69%
    Nitrile 19.67%
    Cereal 19.52%
    Sweet-like 19.26%
    Alkaline 19.09%
    Bread crust 18.98%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    6.35 (neutral)

    Molecular weight
    2253.0 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1026°C

    Flash point

    • 262.11 ˚C est.

  • Synonyms

    • 9030-09-5
    • RefChem:580288
    • Cyclodextrin glucanotransferase
    • 68894-07-5
    • 9041-36-5
    • CM Sepharose CL-6B
    • NIGROSIN B ALCOHOL SOLUBLE
    • 9030-09-5

  • Applications

    Cyclodextrin glucanotransferase (CAS 9030-09-5) is an enzyme that catalyzes the conversion of starch into cyclodextrins, enabling the production of cyclic oligosaccharides that form inclusion complexes with hydrophobic compounds, a function exploited across multiple industries: in food processing, as encapsulation and aroma stabilization agents; in pharmaceuticals, to improve solubility and stability of poorly soluble drugs via cyclodextrin complexation; in cosmetics and personal care, for fragrance encapsulation and stabilization of sensitive actives; in agriculture, for controlled release of agrochemicals; in household and cleaning products, where cyclodextrin complexes aid fragrance retention and solubilize hydrophobic soils; and in industrial coatings, where CD complexes stabilize additives and pigments or enable controlled release in polymer formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 7.29
    methanol 8.51
    isopropanol 4.76
    water 0.03
    ethyl acetate 30.48
    n-propanol 6.46
    acetone 35.47
    n-butanol 5.75
    acetonitrile 20.64
    DMF 21.53
    toluene 11.67
    isobutanol 4.31
    1,4-dioxane 23.66
    methyl acetate 31.31
    THF 48.14
    2-butanone 38.85
    n-pentanol 4.51
    sec-butanol 5.61
    n-hexane 0.15
    ethylene glycol 4.04
    NMP 41.55
    cyclohexane 0.42
    DMSO 36.1
    n-butyl acetate 10.31
    n-octanol 1.45
    chloroform 24.11
    n-propyl acetate 13.06
    acetic acid 63.86
    dichloromethane 28.18
    cyclohexanone 51.08
    propylene glycol 3.59
    isopropyl acetate 14.45
    DMAc 57.58
    2-ethoxyethanol 17.97
    isopentanol 5.16
    n-heptane 0.21
    ethyl formate 19.36
    1,2-dichloroethane 17.95
    n-hexanol 4.02
    2-methoxyethanol 29.39
    isobutyl acetate 5.54
    tetrachloromethane 3.29
    n-pentyl acetate 8.58
    transcutol 38.34
    n-heptanol 2.86
    ethylbenzene 3.02
    MIBK 9.13
    2-propoxyethanol 20.06
    tert-butanol 4.27
    MTBE 3.53
    2-butoxyethanol 13.17
    propionic acid 21.03
    o-xylene 5.25
    formic acid 25.24
    diethyl ether 7.89
    m-xylene 4.42
    p-xylene 3.99
    chlorobenzene 9.57
    dimethyl carbonate 21.65
    n-octane 0.1
    formamide 34.23
    cyclopentanone 52.46
    2-pentanone 22.42
    anisole 6.32
    cyclopentyl methyl ether 10.74
    gamma-butyrolactone 58.25
    1-methoxy-2-propanol 17.42
    pyridine 40.26
    3-pentanone 21.64
    furfural 50.66
    n-dodecane 0.12
    diethylene glycol 20.63
    diisopropyl ether 1.58
    tert-amyl alcohol 4.73
    acetylacetone 37.75
    n-hexadecane 0.14
    acetophenone 13.66
    methyl propionate 27.74
    isopentyl acetate 8.17
    trichloroethylene 44.11
    n-nonanol 1.92
    cyclohexanol 7.71
    benzyl alcohol 10.67
    2-ethylhexanol 3.01
    isooctanol 2.51
    dipropyl ether 3.86
    1,2-dichlorobenzene 7.92
    ethyl lactate 11.19
    propylene carbonate 28.04
    n-methylformamide 20.58
    2-pentanol 3.65
    n-pentane 0.23
    1-propoxy-2-propanol 11.01
    1-methoxy-2-propyl acetate 18.39
    2-(2-methoxypropoxy) propanol 14.11
    mesitylene 1.83
    ε-caprolactone 44.28
    p-cymene 2.34
    epichlorohydrin 54.26
    1,1,1-trichloroethane 14.21
    2-aminoethanol 6.04
    morpholine-4-carbaldehyde 38.23
    sulfolane 54.59
    2,2,4-trimethylpentane 0.17
    2-methyltetrahydrofuran 20.18
    n-hexyl acetate 6.79
    isooctane 0.09
    2-(2-butoxyethoxy)ethanol 17.63
    sec-butyl acetate 8.48
    tert-butyl acetate 9.39
    decalin 0.26
    glycerin 10.64
    diglyme 31.33
    acrylic acid 27.0
    isopropyl myristate 3.19
    n-butyric acid 24.85
    acetyl acetate 29.99
    di(2-ethylhexyl) phthalate 6.13
    ethyl propionate 14.2
    nitromethane 79.69
    1,2-diethoxyethane 11.06
    benzonitrile 14.81
    trioctyl phosphate 3.52
    1-bromopropane 6.82
    gamma-valerolactone 75.44
    n-decanol 1.57
    triethyl phosphate 6.54
    4-methyl-2-pentanol 2.32
    propionitrile 15.23
    vinylene carbonate 30.1
    1,1,2-trichlorotrifluoroethane 52.02
    DMS 14.54
    cumene 1.8
    2-octanol 1.55
    2-hexanone 13.15
    octyl acetate 4.82
    limonene 3.04
    1,2-dimethoxyethane 22.14
    ethyl orthosilicate 5.28
    tributyl phosphate 4.43
    diacetone alcohol 15.73
    N,N-dimethylaniline 4.33
    acrylonitrile 25.24
    aniline 15.69
    1,3-propanediol 11.23
    bromobenzene 8.53
    dibromomethane 15.47
    1,1,2,2-tetrachloroethane 27.23
    2-methyl-cyclohexyl acetate 7.87
    tetrabutyl urea 6.93
    diisobutyl methanol 1.71
    2-phenylethanol 11.3
    styrene 3.59
    dioctyl adipate 6.79
    dimethyl sulfate 27.98
    ethyl butyrate 9.83
    methyl lactate 20.61
    butyl lactate 9.11
    diethyl carbonate 8.59
    propanediol butyl ether 7.67
    triethyl orthoformate 7.36
    p-tert-butyltoluene 1.84
    methyl 4-tert-butylbenzoate 11.11
    morpholine 25.12
    tert-butylamine 1.66
    n-dodecanol 1.24
    dimethoxymethane 23.12
    ethylene carbonate 25.88
    cyrene 18.31
    2-ethoxyethyl acetate 17.92
    2-ethylhexyl acetate 6.55
    1,2,4-trichlorobenzene 12.85
    4-methylpyridine 27.21
    dibutyl ether 2.41
    2,6-dimethyl-4-heptanol 1.71
    DEF 24.11
    dimethyl isosorbide 21.72
    tetrachloroethylene 19.09
    eugenol 12.42
    triacetin 14.21
    span 80 10.26
    1,4-butanediol 4.25
    1,1-dichloroethane 14.26
    2-methyl-1-pentanol 4.78
    methyl formate 21.17
    2-methyl-1-butanol 5.47
    n-decane 0.17
    butyronitrile 11.38
    3,7-dimethyl-1-octanol 1.93
    1-chlorooctane 0.9
    1-chlorotetradecane 0.52
    n-nonane 0.12
    undecane 0.14
    tert-butylcyclohexane 0.17
    cyclooctane 0.15
    cyclopentanol 8.48
    tetrahydropyran 15.75
    tert-amyl methyl ether 4.0
    2,5,8-trioxanonane 23.89
    1-hexene 1.07
    2-isopropoxyethanol 11.41
    2,2,2-trifluoroethanol 23.61
    methyl butyrate 16.25

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction