Cycloartenol

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  • Identifiers

    CAS number
    469-38-5

    Molecular formula
    C30H50O

    SMILES
    C[C@H](CCC=C(C)C)[C@H]1CC[C@@]2([C@@]1(CC[C@]34[C@H]2CC[C@@H]5[C@]3(C4)CC[C@@H](C5(C)C)O)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 88.66%
    Sandalwood 53.89%
    Amber 51.14%
    Dry 46.04%
    Sweet 40.49%
    Cedar 37.74%
    Balsamic 37.39%
    Vetiver 35.75%
    Musk 34.39%
    Waxy 33.89%

     

    Flavor
    Woody 66.59%
    Wood 40.54%
    Sweet 38.29%
    Balsam 35.07%
    Pine 33.61%
    Dry 29.82%
    Camphor 29.14%
    Balsamic 28.32%
    Spice 27.89%
    Fir needle 26.46%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    9.8

    pKa est.
    8.15 (weak base)

    Molecular weight
    426.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    472°C

    Melting point expt.

    • 99 °C

    Flash point

    • 165.89 ˚C est.

  • Synonyms

    • Cycloartenol
    • 469-38-5
    • Cycloarterenol
    • 9beta,19-cyclo-24-lanosten-3beta-ol
    • YU32VE82N3
    • DTXSID60894760
    • 9,19-Cyclolanost-24-en-3-ol, (3beta)-
    • CHEBI:17030
    • (3beta,9beta)-9,19-cyclolanost-24-en-3-ol
    • NSC-670193
    • (1S,3R,6S,8R,11S,12S,15R,16R)-7,7,12,16-tetramethyl-15-[(2R)-6-methylhept-5-en-2-yl]pentacyclo[9.7.0.01,3.03,8.012,16]octadecan-6-ol
    • (1S,3R,6S,8R,11S,12S,15R,16R)-7,7,12,16-tetramethyl-15-((2R)-6-methylhept-5-en-2-yl)pentacyclo(9.7.0.01,3.03,8.012,16)octadecan-6-ol
    • RefChem:129362
    • DTXCID001324322
    • 9beta,19-cyclolanost-24-en-3beta-ol
    • Handianol
    • MFCD00200959
    • Cycloartenol (>90%)
    • 9,19-Cyclo-9beta-lanost-24-en-3beta-ol
    • 9,19-Cyclolanost-24-en-3-ol, (3.beta.)-
    • (3ss)-9,19-Cyclolanost-24-en-3-ol; Handianol
    • UNII-YU32VE82N3
    • Artosenol
    • NSC 670193
    • 9,19-Cyclo-9.beta.-lanost-24-en-3.beta.-ol
    • cycloart-24(25)-enol
    • SCHEMBL560780
    • CHEMBL225815
    • orb1709964
    • 9,19-Cycloart-24-ene, 3beta-ol
    • MSK000519
    • CYCLOART-24-EN-3.BETA.-OL
    • AKOS040732891
    • FC65336
    • DA-62587
    • (3|A)-9,19-Cyclolanost-24-en-3-ol
    • 9beta-9,19-Cyclolanost-24-en-3beta-ol
    • 9,19-CYCLO-24-LANOSTEN-3.BETA.-OL
    • 9,19-cylco-5alpha,9beta-lanost-24en-3betaol
    • C01902
    • Q586501
    • (1S,3R,6S,8R,11S,12S,15R,16R)-15-[(1R)-1,5-dimethylhex-4-enyl]-7,7,12,16-tetramethyl-pentacyclo[9.7.0.01,3.03,8.012,16]octadecan-6-ol
    • 469-38-5

  • Applications

    Cycloartenol is a plant-derived triterpene alcohol primarily used as an intermediate in the synthesis of phytosterols and related steroid compounds. It serves as a starting material for semi-synthetic steroid chemistry and for sterol derivatives and esters used in research and development across cosmetics and personal care. In pharmaceutical and practical chemical synthesis, cycloartenol is viewed as a building block for natural-product–type synthetic routes. It is also explored as a bio-based feedstock for specialty chemicals and polymer-related materials. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 3.26
    methanol 1.03
    isopropanol 3.33
    water 0.02
    ethyl acetate 7.56
    n-propanol 4.54
    acetone 5.48
    n-butanol 6.52
    acetonitrile 1.42
    DMF 5.58
    toluene 11.44
    isobutanol 4.1
    1,4-dioxane 11.58
    methyl acetate 3.79
    THF 18.01
    2-butanone 7.0
    n-pentanol 4.63
    sec-butanol 3.0
    n-hexane 0.78
    ethylene glycol 0.27
    NMP 10.15
    cyclohexane 0.94
    DMSO 2.37
    n-butyl acetate 9.53
    n-octanol 4.44
    chloroform 13.04
    n-propyl acetate 5.91
    acetic acid 2.68
    dichloromethane 7.09
    cyclohexanone 12.85
    propylene glycol 0.61
    isopropyl acetate 11.12
    DMAc 12.21
    2-ethoxyethanol 6.43
    isopentanol 7.07
    n-heptane 1.01
    ethyl formate 1.97
    1,2-dichloroethane 5.0
    n-hexanol 7.0
    2-methoxyethanol 5.95
    isobutyl acetate 7.74
    tetrachloromethane 3.77
    n-pentyl acetate 12.52
    transcutol 29.39
    n-heptanol 7.28
    ethylbenzene 5.41
    MIBK 11.39
    2-propoxyethanol 17.33
    tert-butanol 3.75
    MTBE 7.18
    2-butoxyethanol 17.2
    propionic acid 2.72
    o-xylene 7.09
    formic acid 0.67
    diethyl ether 7.97
    m-xylene 9.61
    p-xylene 5.99
    chlorobenzene 7.84
    dimethyl carbonate 3.88
    n-octane 0.35
    formamide 1.03
    cyclopentanone 11.87
    2-pentanone 9.51
    anisole 10.86
    cyclopentyl methyl ether 11.09
    gamma-butyrolactone 9.25
    1-methoxy-2-propanol 9.0
    pyridine 10.93
    3-pentanone 8.26
    furfural 8.37
    n-dodecane 0.2
    diethylene glycol 5.4
    diisopropyl ether 5.12
    tert-amyl alcohol 3.52
    acetylacetone 11.94
    n-hexadecane 0.24
    acetophenone 9.7
    methyl propionate 6.88
    isopentyl acetate 14.28
    trichloroethylene 11.66
    n-nonanol 5.87
    cyclohexanol 4.8
    benzyl alcohol 6.29
    2-ethylhexanol 6.31
    isooctanol 7.15
    dipropyl ether 9.44
    1,2-dichlorobenzene 8.0
    ethyl lactate 3.66
    propylene carbonate 5.91
    n-methylformamide 1.81
    2-pentanol 4.81
    n-pentane 0.94
    1-propoxy-2-propanol 15.28
    1-methoxy-2-propyl acetate 20.93
    2-(2-methoxypropoxy) propanol 14.84
    mesitylene 6.18
    ε-caprolactone 12.56
    p-cymene 5.73
    epichlorohydrin 10.6
    1,1,1-trichloroethane 8.0
    2-aminoethanol 1.17
    morpholine-4-carbaldehyde 14.75
    sulfolane 9.29
    2,2,4-trimethylpentane 0.8
    2-methyltetrahydrofuran 9.47
    n-hexyl acetate 12.77
    isooctane 0.91
    2-(2-butoxyethoxy)ethanol 18.31
    sec-butyl acetate 7.09
    tert-butyl acetate 14.95
    decalin 1.04
    glycerin 1.29
    diglyme 29.56
    acrylic acid 1.98
    isopropyl myristate 5.72
    n-butyric acid 7.0
    acetyl acetate 6.8
    di(2-ethylhexyl) phthalate 7.06
    ethyl propionate 7.07
    nitromethane 3.54
    1,2-diethoxyethane 11.59
    benzonitrile 5.02
    trioctyl phosphate 4.71
    1-bromopropane 4.78
    gamma-valerolactone 21.44
    n-decanol 3.55
    triethyl phosphate 6.58
    4-methyl-2-pentanol 5.59
    propionitrile 3.16
    vinylene carbonate 6.12
    1,1,2-trichlorotrifluoroethane 7.49
    DMS 8.5
    cumene 4.52
    2-octanol 3.98
    2-hexanone 7.25
    octyl acetate 6.16
    limonene 5.89
    1,2-dimethoxyethane 11.14
    ethyl orthosilicate 8.08
    tributyl phosphate 4.39
    diacetone alcohol 11.3
    N,N-dimethylaniline 9.58
    acrylonitrile 2.79
    aniline 8.21
    1,3-propanediol 3.2
    bromobenzene 9.19
    dibromomethane 5.71
    1,1,2,2-tetrachloroethane 9.51
    2-methyl-cyclohexyl acetate 11.01
    tetrabutyl urea 6.7
    diisobutyl methanol 5.66
    2-phenylethanol 11.32
    styrene 5.36
    dioctyl adipate 7.98
    dimethyl sulfate 5.42
    ethyl butyrate 9.03
    methyl lactate 3.64
    butyl lactate 9.45
    diethyl carbonate 5.81
    propanediol butyl ether 8.45
    triethyl orthoformate 11.43
    p-tert-butyltoluene 6.13
    methyl 4-tert-butylbenzoate 18.97
    morpholine 11.8
    tert-butylamine 3.11
    n-dodecanol 2.16
    dimethoxymethane 9.76
    ethylene carbonate 5.4
    cyrene 11.02
    2-ethoxyethyl acetate 18.01
    2-ethylhexyl acetate 12.05
    1,2,4-trichlorobenzene 11.11
    4-methylpyridine 12.09
    dibutyl ether 5.06
    2,6-dimethyl-4-heptanol 5.66
    DEF 8.94
    dimethyl isosorbide 24.04
    tetrachloroethylene 7.27
    eugenol 16.71
    triacetin 14.42
    span 80 11.52
    1,4-butanediol 1.3
    1,1-dichloroethane 5.43
    2-methyl-1-pentanol 5.4
    methyl formate 1.2
    2-methyl-1-butanol 5.72
    n-decane 0.53
    butyronitrile 4.03
    3,7-dimethyl-1-octanol 5.46
    1-chlorooctane 2.52
    1-chlorotetradecane 0.78
    n-nonane 0.42
    undecane 0.3
    tert-butylcyclohexane 1.12
    cyclooctane 0.6
    cyclopentanol 3.35
    tetrahydropyran 10.47
    tert-amyl methyl ether 6.14
    2,5,8-trioxanonane 19.97
    1-hexene 2.34
    2-isopropoxyethanol 6.99
    2,2,2-trifluoroethanol 1.58
    methyl butyrate 6.32

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction