Cycloartanol

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  • Identifiers

    CAS number
    4657-58-3

    Molecular formula
    C30H52O

    SMILES
    C[C@H](CCCC(C)C)[C@H]1CC[C@@]2([C@@]1(CC[C@]34[C@H]2CC[C@@H]5[C@]3(C4)CC[C@@H](C5(C)C)O)C)C

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  • Odor profile

    Fragrance
    Woody 87.65%
    Amber 51.6%
    Sandalwood 51.14%
    Dry 47.36%
    Waxy 39.48%
    Vetiver 38.52%
    Cedar 37.62%
    Balsamic 37.49%
    Spicy 33.11%
    Musk 30.67%

     

    Flavor
    Woody 52.0%
    Pine 31.66%
    Wood 30.96%
    Camphor 28.21%
    Spice 27.55%
    Balsam 26.61%
    Fir needle 25.43%
    Waxy 24.18%
    Sweet 23.63%
    Dry 23.46%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    10.2

    pKa est.
    7.86 (neutral)

    Molecular weight
    428.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    480°C

    Melting point expt.

    • 101 - 102 °C

    Flash point

    • 169.55 ˚C est.

  • Synonyms

    • Cycloartanol
    • 4657-58-3
    • 3beta-Cycloartanol
    • UNII-52G6Q1IW86
    • 9,19-Cyclolanostan-3beta-ol
    • NSC-226173
    • 52G6Q1IW86
    • Cycloartan-3b-ol
    • 9,19-Cyclo-9beta-lanostan-3beta-ol
    • 9,19-Cyclolanostan-3-ol, (3beta)-
    • 9beta,19-cyclo-lanostan-3beta-ol
    • 24(25)-dihydrocycloartenol
    • 3.BETA.-CYCLOARTANOL
    • 9b,19-Cyclolanostan-3b-ol
    • (1S,3R,6S,8R,11S,12S,15R,16R)-7,7,12,16-tetramethyl-15-[(2R)-6-methylheptan-2-yl]pentacyclo[9.7.0.01,3.03,8.012,16]octadecan-6-ol
    • (3beta,9beta)-9,19-cyclolanost-3-ol
    • 9,19-CYCLOLANOSTAN-3.BETA.-OL
    • 9,19-CYCLOLANOSTAN-3-OL, (3.BETA.)-
    • 9,19-CYCLO-9.BETA.-LANOSTAN-3.BETA.-OL
    • Cycloartanol, 14-methyl-
    • DTXSID30310366
    • (1S,3R,6S,8R,11S,12S,15R,16R)-7,7,12,16-tetramethyl-15-((2R)-6-methylheptan-2-yl)pentacyclo(9.7.0.01,3.03,8.012,16)octadecan-6-ol
    • RefChem:129358
    • DTXCID00261492
    • YABASAWVVRQMEU-UHFFFAOYSA-N
    • 7,7,12,16-Tetramethyl-15-(6-methylheptan-2-yl)pentacyclo[9.7.0.01,3.03,8.012,16]octadecan-6-ol
    • SCHEMBL455049
    • CHEMBL225763
    • orb1682868
    • HY-N3662
    • LMST01100002
    • AKOS040761553
    • FS-9511
    • Q27261004
    • (3)-9,19-Cyclolanostan-3-ol; 3-Cycloartanol; 9,19-Cyclolanostan-3-ol; NSC 226173
    • 4657-58-3

  • Applications

    Cycloartanol may serve as an ingredient or precursor in cosmetic formulations and personal care products; it is considered a potential starting material or intermediate for steroid and other triterpene derivatives in pharmaceutical R&D; in industrial manufacturing it can function as a chemical intermediate for complex triterpene derivatives; and in research and analytical chemistry it may be used as a reference standard or reagent in analytical workflows.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 7.19
    methanol 2.08
    isopropanol 7.54
    water 0.04
    ethyl acetate 15.57
    n-propanol 9.52
    acetone 12.85
    n-butanol 12.54
    acetonitrile 3.22
    DMF 12.13
    toluene 20.41
    isobutanol 8.29
    1,4-dioxane 26.08
    methyl acetate 8.05
    THF 55.18
    2-butanone 14.52
    n-pentanol 8.43
    sec-butanol 6.17
    n-hexane 1.37
    ethylene glycol 0.58
    NMP 20.95
    cyclohexane 1.82
    DMSO 5.73
    n-butyl acetate 18.88
    n-octanol 7.64
    chloroform 24.77
    n-propyl acetate 11.77
    acetic acid 5.55
    dichloromethane 14.57
    cyclohexanone 27.05
    propylene glycol 1.35
    isopropyl acetate 22.68
    DMAc 23.82
    2-ethoxyethanol 12.86
    isopentanol 13.66
    n-heptane 1.91
    ethyl formate 4.16
    1,2-dichloroethane 10.89
    n-hexanol 12.82
    2-methoxyethanol 13.29
    isobutyl acetate 15.04
    tetrachloromethane 7.12
    n-pentyl acetate 23.62
    transcutol 54.81
    n-heptanol 12.62
    ethylbenzene 9.12
    MIBK 22.62
    2-propoxyethanol 32.88
    tert-butanol 8.34
    MTBE 15.92
    2-butoxyethanol 30.81
    propionic acid 5.45
    o-xylene 12.16
    formic acid 1.26
    diethyl ether 17.51
    m-xylene 16.37
    p-xylene 10.5
    chlorobenzene 15.62
    dimethyl carbonate 8.18
    n-octane 0.68
    formamide 2.06
    cyclopentanone 28.98
    2-pentanone 19.28
    anisole 19.1
    cyclopentyl methyl ether 25.82
    gamma-butyrolactone 23.02
    1-methoxy-2-propanol 18.87
    pyridine 22.42
    3-pentanone 15.8
    furfural 17.42
    n-dodecane 0.35
    diethylene glycol 11.21
    diisopropyl ether 10.51
    tert-amyl alcohol 6.92
    acetylacetone 25.52
    n-hexadecane 0.44
    acetophenone 16.59
    methyl propionate 13.92
    isopentyl acetate 27.32
    trichloroethylene 23.72
    n-nonanol 9.79
    cyclohexanol 9.74
    benzyl alcohol 11.26
    2-ethylhexanol 10.82
    isooctanol 12.38
    dipropyl ether 17.67
    1,2-dichlorobenzene 14.69
    ethyl lactate 7.12
    propylene carbonate 13.4
    n-methylformamide 3.86
    2-pentanol 9.17
    n-pentane 1.78
    1-propoxy-2-propanol 28.68
    1-methoxy-2-propyl acetate 39.43
    2-(2-methoxypropoxy) propanol 24.08
    mesitylene 10.82
    ε-caprolactone 25.74
    p-cymene 9.95
    epichlorohydrin 25.62
    1,1,1-trichloroethane 15.75
    2-aminoethanol 2.46
    morpholine-4-carbaldehyde 29.15
    sulfolane 21.14
    2,2,4-trimethylpentane 1.51
    2-methyltetrahydrofuran 24.59
    n-hexyl acetate 23.39
    isooctane 1.69
    2-(2-butoxyethoxy)ethanol 30.9
    sec-butyl acetate 13.33
    tert-butyl acetate 30.74
    decalin 1.82
    glycerin 2.62
    diglyme 55.88
    acrylic acid 4.09
    isopropyl myristate 9.95
    n-butyric acid 13.93
    acetyl acetate 13.51
    di(2-ethylhexyl) phthalate 11.61
    ethyl propionate 12.92
    nitromethane 7.58
    1,2-diethoxyethane 23.14
    benzonitrile 9.64
    trioctyl phosphate 8.06
    1-bromopropane 9.41
    gamma-valerolactone 45.36
    n-decanol 6.05
    triethyl phosphate 11.44
    4-methyl-2-pentanol 9.91
    propionitrile 6.31
    vinylene carbonate 12.95
    1,1,2-trichlorotrifluoroethane 14.61
    DMS 16.35
    cumene 7.59
    2-octanol 7.08
    2-hexanone 13.8
    octyl acetate 11.15
    limonene 10.7
    1,2-dimethoxyethane 23.39
    ethyl orthosilicate 13.5
    tributyl phosphate 7.8
    diacetone alcohol 22.94
    N,N-dimethylaniline 15.81
    acrylonitrile 5.47
    aniline 15.0
    1,3-propanediol 6.69
    bromobenzene 17.71
    dibromomethane 11.63
    1,1,2,2-tetrachloroethane 19.0
    2-methyl-cyclohexyl acetate 19.06
    tetrabutyl urea 11.37
    diisobutyl methanol 9.94
    2-phenylethanol 19.35
    styrene 9.43
    dioctyl adipate 13.83
    dimethyl sulfate 11.2
    ethyl butyrate 17.38
    methyl lactate 7.32
    butyl lactate 17.26
    diethyl carbonate 11.0
    propanediol butyl ether 15.77
    triethyl orthoformate 20.3
    p-tert-butyltoluene 10.7
    methyl 4-tert-butylbenzoate 31.52
    morpholine 26.6
    tert-butylamine 6.56
    n-dodecanol 3.8
    dimethoxymethane 22.28
    ethylene carbonate 11.52
    cyrene 19.3
    2-ethoxyethyl acetate 33.99
    2-ethylhexyl acetate 22.48
    1,2,4-trichlorobenzene 19.14
    4-methylpyridine 22.98
    dibutyl ether 9.57
    2,6-dimethyl-4-heptanol 9.94
    DEF 17.64
    dimethyl isosorbide 43.21
    tetrachloroethylene 13.7
    eugenol 26.22
    triacetin 25.9
    span 80 19.06
    1,4-butanediol 2.63
    1,1-dichloroethane 11.66
    2-methyl-1-pentanol 9.53
    methyl formate 2.74
    2-methyl-1-butanol 10.94
    n-decane 0.99
    butyronitrile 8.19
    3,7-dimethyl-1-octanol 9.7
    1-chlorooctane 4.71
    1-chlorotetradecane 1.42
    n-nonane 0.79
    undecane 0.55
    tert-butylcyclohexane 1.97
    cyclooctane 1.06
    cyclopentanol 8.08
    tetrahydropyran 24.84
    tert-amyl methyl ether 12.94
    2,5,8-trioxanonane 33.62
    1-hexene 4.27
    2-isopropoxyethanol 13.46
    2,2,2-trifluoroethanol 3.4
    methyl butyrate 12.33

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction