Cyazofamid

Overview IFRA Request a quote

  • Identifiers

    CAS number
    120116-88-3

    Molecular formula
    C13H13ClN4O2S

    SMILES
    CC1=CC=C(C=C1)C2=C(N=C(N2S(=O)(=O)N(C)C)C#N)Cl

    Safety labels

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 68.25%
    Bitter 22.09%
    Cooked 20.62%
    Savory 18.3%
    Roasted 16.48%
    Grape 16.21%
    Citrus 15.39%
    Meaty 15.05%
    Cooling 13.6%
    Burnt 13.59%

     

    Flavor
    Bitter 86.75%
    Odorless 34.09%
    Bland 22.26%
    Nitrile 19.96%
    Cedarleaf 18.22%
    Very strong 18.2%
    Bread crust 18.17%
    Taco 18.17%
    Roasted peanuts 18.07%
    Sweet-like 17.79%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.6

    pKa est.
    5.89 (weak acid)

    Molecular weight
    324.79 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    379°C

    Melting point expt.

    • 152.7 °C

    Flash point

    • 228.86 ˚C est.

    Solubility expt.

    • Solvent solubility (all in g/100 mL, 21.2 °C): hexane, 0.003; methanol, 0.174, acetonitrile, 3.095, dichloroethane, 10.212; toluene, 0.600, ethyl acetate, 1.649; acetone, 4.564, octanol, 0.004
    • In water, 0.107 at pH 7; 0.121 at pH 5; 0.109 at pH 9 (all in mg/L at 20 °C)

  • Synonyms

    • Cyazofamid
    • 120116-88-3
    • Ranman
    • Cyazofamid [ISO]
    • 1H-Imidazole-1-sulfonamide, 4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-
    • 4-chloro-2-cyano-N,N-dimethyl-5-p-tolylimidazole-1-sulfonamide
    • 4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide
    • UNII-QJC4S2YQ4B
    • QJC4S2YQ4B
    • DTXSID9034492
    • CHEBI:81841
    • HSDB 7505
    • CYAZOFAMID [MI]
    • CYAZOFAMID [HSDB]
    • 4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)imidazole-1-sulfonamide
    • DTXCID7014492
    • IKF-916
    • DNDI1729591
    • Cyamidazosulfamid
    • 4-Chloro-1-(dimethylaminosulfonyl)-5-(p-tolyl)imidazole-2-carbonitrile
    • 4-Chloro-2-cyano-N,N-dimethyl-5-(p-tolyl)-1H-imidazole-1-sulfonamide
    • Cyazofamid?
    • MFCD04112761
    • SCHEMBL22923
    • CHEMBL1863429
    • BCP24647
    • Tox21_300788
    • AKOS015917604
    • FC20673
    • USEPA/OPP Pesticide Code: 085651
    • NCGC00168297-01
    • NCGC00168297-02
    • NCGC00254692-01
    • 1ST21230
    • AS-76305
    • C3655
    • CAS-120116-88-3
    • CS-0133976
    • NS00008379
    • Cyazofamid, PESTANAL(R), analytical standard
    • C18573
    • D95239
    • EN300-256544
    • 4Chloro2cyanoN,Ndimethyl5ptolylimidazole1sulfonamide
    • Q15632870
    • 4-Chlor-2-cyano-N,N-dimethyl-5-p-tolylimidazol-1-sulfonamid
    • 4Chloro2cyanoN,Ndimethyl5(4methylphenyl)1Himidazole1sulfonamide
    • 4-Chlor-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazol-1-sulfonamid
    • 4-Chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide;4-Chloro-2-cyano-N,N-dimethyl-5-p-tolylimidazole-1-sulfo namide;BAS 54500F
    • 601-671-8

  • Applications

    Cyazofamid (CAS 120116-88-3) is used primarily as a fungicide to protect crops from oomycete diseases such as Phytophthora and Pythium. Practically, applications cover vegetables and fruits, including potatoes, tomatoes, cucumbers, lettuce, grapes, and strawberries, delivered as foliar sprays and soil drenches in both field and greenhouse production. It is commonly integrated into pest management programs and is applied at commercial scale to manage oomycete diseases. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 6.36
    methanol 10.03
    isopropanol 2.35
    water 0.2
    ethyl acetate 18.62
    n-propanol 4.07
    acetone 36.71
    n-butanol 2.59
    acetonitrile 50.13
    DMF 189.24
    toluene 4.11
    isobutanol 2.47
    1,4-dioxane 22.7
    methyl acetate 37.39
    THF 52.66
    2-butanone 30.73
    n-pentanol 2.81
    sec-butanol 2.47
    n-hexane 0.02
    ethylene glycol 7.54
    NMP 212.68
    cyclohexane 0.12
    DMSO 65.72
    n-butyl acetate 17.54
    n-octanol 2.27
    chloroform 60.22
    n-propyl acetate 17.29
    acetic acid 34.14
    dichloromethane 57.66
    cyclohexanone 45.6
    propylene glycol 5.86
    isopropyl acetate 11.06
    DMAc 189.94
    2-ethoxyethanol 18.06
    isopentanol 2.51
    n-heptane 0.07
    ethyl formate 30.38
    1,2-dichloroethane 25.23
    n-hexanol 3.86
    2-methoxyethanol 35.1
    isobutyl acetate 11.48
    tetrachloromethane 2.77
    n-pentyl acetate 11.65
    transcutol 18.09
    n-heptanol 3.54
    ethylbenzene 1.88
    MIBK 8.54
    2-propoxyethanol 24.64
    tert-butanol 2.62
    MTBE 2.28
    2-butoxyethanol 17.54
    propionic acid 15.92
    o-xylene 2.34
    formic acid 33.22
    diethyl ether 2.27
    m-xylene 1.93
    p-xylene 4.12
    chlorobenzene 17.05
    dimethyl carbonate 35.45
    n-octane 0.05
    formamide 69.96
    cyclopentanone 89.85
    2-pentanone 14.4
    anisole 13.08
    cyclopentyl methyl ether 8.01
    gamma-butyrolactone 118.08
    1-methoxy-2-propanol 16.8
    pyridine 59.64
    3-pentanone 11.25
    furfural 146.22
    n-dodecane 0.07
    diethylene glycol 27.24
    diisopropyl ether 0.49
    tert-amyl alcohol 2.69
    acetylacetone 42.31
    n-hexadecane 0.09
    acetophenone 30.09
    methyl propionate 23.0
    isopentyl acetate 16.43
    trichloroethylene 107.05
    n-nonanol 2.41
    cyclohexanol 2.92
    benzyl alcohol 16.83
    2-ethylhexanol 2.95
    isooctanol 2.95
    dipropyl ether 2.26
    1,2-dichlorobenzene 18.36
    ethyl lactate 17.15
    propylene carbonate 68.99
    n-methylformamide 72.39
    2-pentanol 1.08
    n-pentane 0.03
    1-propoxy-2-propanol 14.75
    1-methoxy-2-propyl acetate 27.12
    2-(2-methoxypropoxy) propanol 17.31
    mesitylene 0.93
    ε-caprolactone 43.25
    p-cymene 2.5
    epichlorohydrin 93.21
    1,1,1-trichloroethane 19.5
    2-aminoethanol 8.86
    morpholine-4-carbaldehyde 117.51
    sulfolane 112.04
    2,2,4-trimethylpentane 0.04
    2-methyltetrahydrofuran 20.22
    n-hexyl acetate 9.24
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 16.7
    sec-butyl acetate 9.79
    tert-butyl acetate 11.53
    decalin 0.1
    glycerin 16.65
    diglyme 34.19
    acrylic acid 29.95
    isopropyl myristate 3.96
    n-butyric acid 16.47
    acetyl acetate 24.07
    di(2-ethylhexyl) phthalate 11.02
    ethyl propionate 13.91
    nitromethane 155.37
    1,2-diethoxyethane 7.39
    benzonitrile 38.82
    trioctyl phosphate 6.22
    1-bromopropane 4.02
    gamma-valerolactone 128.7
    n-decanol 1.88
    triethyl phosphate 10.98
    4-methyl-2-pentanol 1.02
    propionitrile 20.11
    vinylene carbonate 78.33
    1,1,2-trichlorotrifluoroethane 96.3
    DMS 22.7
    cumene 1.34
    2-octanol 1.9
    2-hexanone 14.39
    octyl acetate 6.15
    limonene 2.49
    1,2-dimethoxyethane 32.4
    ethyl orthosilicate 8.2
    tributyl phosphate 7.18
    diacetone alcohol 19.21
    N,N-dimethylaniline 8.48
    acrylonitrile 58.46
    aniline 11.51
    1,3-propanediol 9.67
    bromobenzene 14.64
    dibromomethane 20.07
    1,1,2,2-tetrachloroethane 56.22
    2-methyl-cyclohexyl acetate 15.91
    tetrabutyl urea 11.75
    diisobutyl methanol 1.42
    2-phenylethanol 19.88
    styrene 3.4
    dioctyl adipate 9.78
    dimethyl sulfate 68.65
    ethyl butyrate 14.06
    methyl lactate 28.34
    butyl lactate 14.88
    diethyl carbonate 13.82
    propanediol butyl ether 12.61
    triethyl orthoformate 10.37
    p-tert-butyltoluene 2.16
    methyl 4-tert-butylbenzoate 20.2
    morpholine 29.86
    tert-butylamine 0.87
    n-dodecanol 1.37
    dimethoxymethane 38.23
    ethylene carbonate 45.61
    cyrene 43.14
    2-ethoxyethyl acetate 20.27
    2-ethylhexyl acetate 12.89
    1,2,4-trichlorobenzene 32.01
    4-methylpyridine 49.68
    dibutyl ether 1.54
    2,6-dimethyl-4-heptanol 1.42
    DEF 28.87
    dimethyl isosorbide 43.28
    tetrachloroethylene 26.16
    eugenol 25.25
    triacetin 20.43
    span 80 12.59
    1,4-butanediol 5.13
    1,1-dichloroethane 16.7
    2-methyl-1-pentanol 3.0
    methyl formate 73.93
    2-methyl-1-butanol 2.45
    n-decane 0.09
    butyronitrile 14.62
    3,7-dimethyl-1-octanol 2.55
    1-chlorooctane 0.88
    1-chlorotetradecane 0.47
    n-nonane 0.07
    undecane 0.08
    tert-butylcyclohexane 0.07
    cyclooctane 0.03
    cyclopentanol 7.01
    tetrahydropyran 9.77
    tert-amyl methyl ether 2.14
    2,5,8-trioxanonane 25.69
    1-hexene 0.33
    2-isopropoxyethanol 11.19
    2,2,2-trifluoroethanol 29.47
    methyl butyrate 21.9

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction