Corosolic Acid

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  • Identifiers

    CAS number
    4547-24-4

    Molecular formula
    C30H48O4

    SMILES
    C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(C[C@H]([C@@H](C5(C)C)O)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O

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  • Odor profile

    Fragrance
    Woody 80.96%
    Amber 49.18%
    Balsamic 48.4%
    Cedar 45.46%
    Dry 44.3%
    Spicy 43.02%
    Sandalwood 37.76%
    Herbal 35.59%
    Camphoreous 35.51%
    Pine 33.36%

     

    Flavor
    Woody 55.51%
    Pine 43.45%
    Camphor 43.24%
    Balsam 42.22%
    Herbal 41.65%
    Sweet 37.34%
    Bitter 33.49%
    Spicy 30.77%
    Earthy 30.49%
    Minty 29.47%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.4

    pKa est.
    5.67 (weak acid)

    Molecular weight
    472.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    181°C

    Flash point

    • 268.05 ˚C est.

  • Synonyms

    • Corosolic acid
    • 4547-24-4
    • 2-alpha-Hydroxyursolic acid
    • AMX2I57A98
    • DTXSID70904142
    • (1S,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
    • Urs-12-en-28-oic acid, 2,3-dihydroxy-, (2alpha,3beta)-
    • 2alpha-hydroxyursoloic acid
    • RefChem:33604
    • DTXCID501332027
    • 610-253-4
    • 2alpha-Hydroxyursolic acid
    • Colosic acid
    • Corosolic-acid
    • MFCD06794973
    • Glucosol
    • 2alpha,3beta-dihydroxyurs-12-en-28-oic acid
    • CHEMBL391533
    • (1S,2R,4aS,6aS,6bR,8aR,10R,11R,12aR,12bR,14bS)-10,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
    • (2alpha,3beta)-2,3-Dihydroxyurs-12-en-28-oic acid
    • Corsolic acid
    • (2a,3b)-2,3-dihydroxy-urs-12-en-28-oic acid
    • UNII-AMX2I57A98
    • Colosolic acid; Corsolic acid; Glucosol
    • Corosolic acid (Standard)
    • 2alpha-hydroxy ursolic acid
    • 2alpha-hydroxyl ursolic acid
    • MLS000563488
    • SCHEMBL335528
    • orb1304246
    • COROSOLIC ACID [USP-RS]
    • CHEBI:67895
    • HY-N0280R
    • Ursolic acid (2-alpha-hydroxy-)
    • Corosolic acid, analytical standard
    • HY-N0280
    • MSK40240
    • BDBM50222205
    • s9041
    • 2-.ALPHA.-HYDROXYURSOLIC ACID
    • AKOS032948365
    • CCG-269470
    • CS-3798
    • EBC-457055
    • FC64987
    • NCGC00247602-01
    • AC-33935
    • BS-42423
    • SMR000232346
    • SY068845
    • 547C244
    • Q5172335
    • BRD-K27885593-001-06-8
    • (2alpha,3beta)-2,3-Dihydroxy-urs-12-en-28-oic Acid
    • 2alpha,2beta-dihydroxy-18beta-ursan-12-ene-28-oic acid
    • COROSOLIC ACID (CONSTITUENT OF BANABA LEAF) [DSC]
    • Corosolic acid from Lagerstroemia speciosa, >=98% (HPLC)
    • Corosolic acid, United States Pharmacopeia (USP) Reference Standard
    • URS-12-EN-28-OIC ACID, 2,3-DIHYDROXY-, (2.ALPHA.,3.BETA.)-
    • 4547-24-4

  • Applications

    Corosolic Acid (CAS 4547-24-4) finds utility primarily in research and development contexts. It is widely used as a reference standard for analytical characterization of Banaba leaf extracts (HPLC/LC-MS). In nutraceutical and botanical product development, it is commonly evaluated as an active constituent marker in dietary supplement formulations derived from Banaba. It serves as an intermediate or building block in synthetic routes for other pentacyclic triterpenoids, supporting pharmaceutical and cosmetic R&D. In cosmetics and personal care formulation work, it is occasionally considered for inclusion in prototype products and formulation stability studies. Additionally, it functions as a research chemical for natural product libraries and analytical method development.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 9.36
    methanol 12.85
    isopropanol 7.06
    water 0.01
    ethyl acetate 2.84
    n-propanol 12.82
    acetone 4.76
    n-butanol 8.89
    acetonitrile 1.16
    DMF 48.55
    toluene 3.66
    isobutanol 6.71
    1,4-dioxane 24.54
    methyl acetate 2.9
    THF 49.52
    2-butanone 6.17
    n-pentanol 5.99
    sec-butanol 4.05
    n-hexane 0.21
    ethylene glycol 1.36
    NMP 24.17
    cyclohexane 0.2
    DMSO 12.37
    n-butyl acetate 3.45
    n-octanol 2.75
    chloroform 8.24
    n-propyl acetate 2.31
    acetic acid 4.0
    dichloromethane 4.71
    cyclohexanone 9.25
    propylene glycol 3.22
    isopropyl acetate 2.8
    DMAc 23.49
    2-ethoxyethanol 14.35
    isopentanol 4.75
    n-heptane 0.19
    ethyl formate 2.0
    1,2-dichloroethane 3.19
    n-hexanol 6.76
    2-methoxyethanol 25.17
    isobutyl acetate 2.15
    tetrachloromethane 1.2
    n-pentyl acetate 5.99
    transcutol 21.87
    n-heptanol 5.78
    ethylbenzene 1.85
    MIBK 3.52
    2-propoxyethanol 33.88
    tert-butanol 4.03
    MTBE 3.41
    2-butoxyethanol 20.02
    propionic acid 3.36
    o-xylene 2.05
    formic acid 2.73
    diethyl ether 4.97
    m-xylene 2.6
    p-xylene 1.75
    chlorobenzene 2.68
    dimethyl carbonate 3.73
    n-octane 0.08
    formamide 3.6
    cyclopentanone 16.44
    2-pentanone 5.13
    anisole 4.81
    cyclopentyl methyl ether 9.28
    gamma-butyrolactone 12.25
    1-methoxy-2-propanol 25.56
    pyridine 13.95
    3-pentanone 3.75
    furfural 10.36
    n-dodecane 0.03
    diethylene glycol 15.46
    diisopropyl ether 1.08
    tert-amyl alcohol 2.84
    acetylacetone 5.43
    n-hexadecane 0.04
    acetophenone 4.35
    methyl propionate 4.7
    isopentyl acetate 3.82
    trichloroethylene 7.93
    n-nonanol 3.11
    cyclohexanol 3.57
    benzyl alcohol 6.39
    2-ethylhexanol 2.39
    isooctanol 3.99
    dipropyl ether 3.31
    1,2-dichlorobenzene 2.4
    ethyl lactate 2.61
    propylene carbonate 3.9
    n-methylformamide 10.77
    2-pentanol 3.13
    n-pentane 0.22
    1-propoxy-2-propanol 18.91
    1-methoxy-2-propyl acetate 9.61
    2-(2-methoxypropoxy) propanol 9.61
    mesitylene 1.37
    ε-caprolactone 7.77
    p-cymene 1.28
    epichlorohydrin 16.62
    1,1,1-trichloroethane 2.17
    2-aminoethanol 6.3
    morpholine-4-carbaldehyde 36.75
    sulfolane 16.1
    2,2,4-trimethylpentane 0.14
    2-methyltetrahydrofuran 10.01
    n-hexyl acetate 5.75
    isooctane 0.13
    2-(2-butoxyethoxy)ethanol 15.47
    sec-butyl acetate 1.72
    tert-butyl acetate 3.54
    decalin 0.19
    glycerin 5.9
    diglyme 23.88
    acrylic acid 3.35
    isopropyl myristate 1.34
    n-butyric acid 5.17
    acetyl acetate 1.96
    di(2-ethylhexyl) phthalate 3.22
    ethyl propionate 2.18
    nitromethane 5.58
    1,2-diethoxyethane 5.78
    benzonitrile 3.09
    trioctyl phosphate 2.17
    1-bromopropane 1.84
    gamma-valerolactone 29.72
    n-decanol 1.48
    triethyl phosphate 1.67
    4-methyl-2-pentanol 2.05
    propionitrile 2.25
    vinylene carbonate 4.65
    1,1,2-trichlorotrifluoroethane 12.42
    DMS 4.4
    cumene 1.22
    2-octanol 2.28
    2-hexanone 3.65
    octyl acetate 2.25
    limonene 1.4
    1,2-dimethoxyethane 16.82
    ethyl orthosilicate 1.99
    tributyl phosphate 1.57
    diacetone alcohol 6.25
    N,N-dimethylaniline 4.17
    acrylonitrile 3.01
    aniline 5.28
    1,3-propanediol 10.06
    bromobenzene 2.34
    dibromomethane 3.0
    1,1,2,2-tetrachloroethane 6.78
    2-methyl-cyclohexyl acetate 3.15
    tetrabutyl urea 2.68
    diisobutyl methanol 1.41
    2-phenylethanol 8.08
    styrene 1.8
    dioctyl adipate 2.74
    dimethyl sulfate 5.97
    ethyl butyrate 2.24
    methyl lactate 5.36
    butyl lactate 7.04
    diethyl carbonate 1.35
    propanediol butyl ether 14.01
    triethyl orthoformate 2.94
    p-tert-butyltoluene 1.38
    methyl 4-tert-butylbenzoate 8.45
    morpholine 37.53
    tert-butylamine 1.7
    n-dodecanol 0.68
    dimethoxymethane 31.16
    ethylene carbonate 3.63
    cyrene 10.78
    2-ethoxyethyl acetate 10.37
    2-ethylhexyl acetate 2.84
    1,2,4-trichlorobenzene 3.84
    4-methylpyridine 8.68
    dibutyl ether 1.29
    2,6-dimethyl-4-heptanol 1.41
    DEF 7.12
    dimethyl isosorbide 14.99
    tetrachloroethylene 5.39
    eugenol 9.94
    triacetin 5.37
    span 80 9.17
    1,4-butanediol 3.73
    1,1-dichloroethane 2.39
    2-methyl-1-pentanol 3.43
    methyl formate 5.4
    2-methyl-1-butanol 4.7
    n-decane 0.1
    butyronitrile 2.26
    3,7-dimethyl-1-octanol 1.99
    1-chlorooctane 0.65
    1-chlorotetradecane 0.13
    n-nonane 0.09
    undecane 0.05
    tert-butylcyclohexane 0.19
    cyclooctane 0.12
    cyclopentanol 5.62
    tetrahydropyran 12.0
    tert-amyl methyl ether 2.51
    2,5,8-trioxanonane 13.41
    1-hexene 0.88
    2-isopropoxyethanol 8.5
    2,2,2-trifluoroethanol 1.61
    methyl butyrate 2.73

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction