Corosin

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  • Identifiers

    CAS number
    53527-49-4

    Molecular formula
    C30H46O7

    SMILES
    CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C(=O)O)O)O)C)C)C2C1(C)O)C)C(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Woody 54.76%
    Odorless 42.86%
    Spicy 40.01%
    Balsamic 38.32%
    Cooling 31.62%
    Amber 31.28%
    Cedar 31.08%
    Herbal 29.88%
    Dry 29.42%
    Mint 27.52%

     

    Flavor
    Bitter 58.23%
    Odorless 28.66%
    Minty 26.36%
    Pine 24.86%
    Balsam 24.03%
    Camphor 23.82%
    Cedarleaf 23.3%
    Sweet-like 22.74%
    Woody 22.33%
    Patchouli 22.22%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.2

    pKa est.
    4.57 (weak acid)

    Molecular weight
    518.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    218°C

    Melting point expt.

    • 300 °C

    Flash point

    • 305.61 ˚C est.

  • Synonyms

    • Corosin
    • 2,3,12-trihydroxy-4,6a,6b,11,12,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,11,12a,14,14a-tetradecahydropicene-4,8a-dicarboxylic acid
    • RefChem:1082223
    • 53527-49-4
    • Capsularone
    • Vismiaefolic acid
    • 2,3,19-trihydroxyurs-12-ene-23,28-dioic acid
    • Trachelosperogenin A
    • DTXSID80301608
    • CHEBI:167968
    • NSC144943
    • NSC-144943
    • 53527-49-4

  • Applications

    Corosin, CAS 53527-49-4, is commonly considered for use as a fragrance ingredient and odorant, with potential as a fixative in perfumery formulations; it may also serve as an intermediate in organic synthesis. In consumer products, it may be evaluated for cosmetics and personal care, as well as household cleaning formulations. In industrial settings, it can function as a solvent or co-solvent and as a processing aid in coatings, inks, and plastics formulations. Overall, its use is typically subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 15.96
    methanol 35.58
    isopropanol 6.29
    water 0.01
    ethyl acetate 2.06
    n-propanol 9.96
    acetone 7.24
    n-butanol 4.37
    acetonitrile 1.51
    DMF 60.75
    toluene 1.12
    isobutanol 3.42
    1,4-dioxane 24.61
    methyl acetate 2.77
    THF 62.27
    2-butanone 5.41
    n-pentanol 3.16
    sec-butanol 2.26
    n-hexane 0.07
    ethylene glycol 4.11
    NMP 25.96
    cyclohexane 0.09
    DMSO 43.82
    n-butyl acetate 1.62
    n-octanol 1.22
    chloroform 4.52
    n-propyl acetate 1.34
    acetic acid 8.37
    dichloromethane 3.09
    cyclohexanone 7.59
    propylene glycol 6.32
    isopropyl acetate 1.46
    DMAc 27.95
    2-ethoxyethanol 17.06
    isopentanol 2.07
    n-heptane 0.05
    ethyl formate 2.46
    1,2-dichloroethane 2.33
    n-hexanol 2.84
    2-methoxyethanol 43.11
    isobutyl acetate 0.82
    tetrachloromethane 0.62
    n-pentyl acetate 2.33
    transcutol 11.89
    n-heptanol 2.26
    ethylbenzene 0.56
    MIBK 1.78
    2-propoxyethanol 24.99
    tert-butanol 3.06
    MTBE 1.47
    2-butoxyethanol 11.27
    propionic acid 3.24
    o-xylene 0.61
    formic acid 8.88
    diethyl ether 2.55
    m-xylene 0.69
    p-xylene 0.61
    chlorobenzene 0.87
    dimethyl carbonate 3.62
    n-octane 0.03
    formamide 10.77
    cyclopentanone 17.25
    2-pentanone 3.36
    anisole 2.14
    cyclopentyl methyl ether 5.12
    gamma-butyrolactone 14.76
    1-methoxy-2-propanol 24.03
    pyridine 10.5
    3-pentanone 2.38
    furfural 10.01
    n-dodecane 0.01
    diethylene glycol 19.74
    diisopropyl ether 0.39
    tert-amyl alcohol 1.66
    acetylacetone 4.53
    n-hexadecane 0.02
    acetophenone 2.3
    methyl propionate 3.54
    isopentyl acetate 1.39
    trichloroethylene 4.79
    n-nonanol 1.3
    cyclohexanol 1.64
    benzyl alcohol 3.6
    2-ethylhexanol 0.78
    isooctanol 1.33
    dipropyl ether 1.22
    1,2-dichlorobenzene 0.73
    ethyl lactate 1.78
    propylene carbonate 3.13
    n-methylformamide 20.35
    2-pentanol 1.22
    n-pentane 0.07
    1-propoxy-2-propanol 9.36
    1-methoxy-2-propyl acetate 4.75
    2-(2-methoxypropoxy) propanol 4.94
    mesitylene 0.37
    ε-caprolactone 5.79
    p-cymene 0.29
    epichlorohydrin 19.04
    1,1,1-trichloroethane 1.0
    2-aminoethanol 11.69
    morpholine-4-carbaldehyde 39.16
    sulfolane 20.2
    2,2,4-trimethylpentane 0.03
    2-methyltetrahydrofuran 7.83
    n-hexyl acetate 2.38
    isooctane 0.03
    2-(2-butoxyethoxy)ethanol 8.42
    sec-butyl acetate 0.73
    tert-butyl acetate 1.63
    decalin 0.05
    glycerin 12.15
    diglyme 14.94
    acrylic acid 4.17
    isopropyl myristate 0.49
    n-butyric acid 3.61
    acetyl acetate 1.34
    di(2-ethylhexyl) phthalate 1.33
    ethyl propionate 1.21
    nitromethane 11.69
    1,2-diethoxyethane 3.08
    benzonitrile 1.57
    trioctyl phosphate 0.9
    1-bromopropane 0.87
    gamma-valerolactone 34.39
    n-decanol 0.63
    triethyl phosphate 0.73
    4-methyl-2-pentanol 0.73
    propionitrile 1.68
    vinylene carbonate 3.71
    1,1,2-trichlorotrifluoroethane 13.66
    DMS 2.2
    cumene 0.35
    2-octanol 0.88
    2-hexanone 2.27
    octyl acetate 0.95
    limonene 0.35
    1,2-dimethoxyethane 19.36
    ethyl orthosilicate 0.78
    tributyl phosphate 0.64
    diacetone alcohol 3.97
    N,N-dimethylaniline 1.7
    acrylonitrile 2.92
    aniline 2.42
    1,3-propanediol 15.47
    bromobenzene 0.65
    dibromomethane 1.67
    1,1,2,2-tetrachloroethane 4.26
    2-methyl-cyclohexyl acetate 1.19
    tetrabutyl urea 1.29
    diisobutyl methanol 0.41
    2-phenylethanol 3.77
    styrene 0.57
    dioctyl adipate 1.08
    dimethyl sulfate 5.82
    ethyl butyrate 0.98
    methyl lactate 5.04
    butyl lactate 2.94
    diethyl carbonate 0.62
    propanediol butyl ether 8.35
    triethyl orthoformate 1.21
    p-tert-butyltoluene 0.3
    methyl 4-tert-butylbenzoate 3.27
    morpholine 36.53
    tert-butylamine 0.79
    n-dodecanol 0.31
    dimethoxymethane 35.95
    ethylene carbonate 2.94
    cyrene 7.86
    2-ethoxyethyl acetate 5.09
    2-ethylhexyl acetate 1.01
    1,2,4-trichlorobenzene 1.21
    4-methylpyridine 5.11
    dibutyl ether 0.55
    2,6-dimethyl-4-heptanol 0.41
    DEF 5.09
    dimethyl isosorbide 8.59
    tetrachloroethylene 3.51
    eugenol 4.41
    triacetin 2.5
    span 80 4.5
    1,4-butanediol 4.95
    1,1-dichloroethane 1.29
    2-methyl-1-pentanol 1.53
    methyl formate 11.16
    2-methyl-1-butanol 1.93
    n-decane 0.04
    butyronitrile 1.48
    3,7-dimethyl-1-octanol 0.7
    1-chlorooctane 0.26
    1-chlorotetradecane 0.06
    n-nonane 0.04
    undecane 0.02
    tert-butylcyclohexane 0.05
    cyclooctane 0.04
    cyclopentanol 4.48
    tetrahydropyran 8.15
    tert-amyl methyl ether 1.08
    2,5,8-trioxanonane 8.28
    1-hexene 0.33
    2-isopropoxyethanol 6.49
    2,2,2-trifluoroethanol 2.42
    methyl butyrate 1.75

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction