Coniferyl Alcohol

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    458-35-5

    Molecular formula
    C10H12O3

    SMILES
    COC1=C(C=CC(=C1)/C=C/CO)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Sweet 82.66%
    Vanilla 79.58%
    Spicy 68.51%
    Balsamic 59.62%
    Creamy 47.84%
    Powdery 46.42%
    Floral 46.26%
    Phenolic 44.52%
    Clove 43.53%
    Cinnamon 38.07%

    Scent© AI

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    9.61 (weak base)

    Molecular weight
    180.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    358°C

    Melting point expt.

    • 74 °C

    Flash point est.
    163.49 ˚C

  • Synonyms

    • CONIFERYL ALCOHOL
    • 458-35-5
    • Coniferol
    • 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenol
    • 32811-40-8
    • (E)-Coniferyl alcohol
    • trans-Coniferyl alcohol
    • gamma-Hydroxyisoeugenol
    • (e)-coniferol
    • Coniferyl alcohol, E-
    • 4-Hydroxy-3-methoxycinnamic alcohol
    • 3-(4-Hydroxy-3-methoxyphenyl)-2-propen-1-ol
    • 4-(3-Hydroxy-1-propenyl)-2-methoxyphenol
    • 4-[(1E)-3-hydroxyprop-1-en-1-yl]-2-methoxyphenol
    • 4-Hydroxy-3-methoxycinnamyl alcohol
    • Coniferyl alcohol [MI]
    • UNII-E7SM92591P
    • trans-coniferol
    • CHEBI:17745
    • 4-[(E)-3-hydroxyprop-1-enyl]-2-methoxyphenol
    • E7SM92591P
    • Coniferylic alcohol
    • MFCD00002922
    • E-Coniferyl alcohol
    • .gamma.-Hydroxyisoeugenol
    • 4-(3-Hydroxy-1-propen-1-yl)-2-methoxyphenol
    • 4-((1E)-3-Hydroxy-1-propenyl)-2-methoxyphenol
    • 4-[(1E)-3-Hydroxy-1-propenyl]-2-methoxyphenol
    • 2-Propen-1-ol, 3-(4-hydroxy-3-methoxyphenyl)-
    • p-Hydroxy-m-methoxycinnamyl alcohol
    • Phenol, 4-(3-hydroxy-1-propenyl)-2-methoxy-
    • Phenol, 4-(3-hydroxy-1-propenyl)-2-methoxy-, (E)-
    • 3-(4-Hydroxy-3-methoxyphenyl)allyl alcohol
    • EINECS 207-277-9
    • 2-Propen-1-ol, 3-(4-hydroxy-3-methoxyphenyl), (E)-
    • 4-((1E)-3-HYDROXY-1-PROPEN-1-YL)-2-METHOXYPHENOL
    • PHENOL, 4-((1E)-3-HYDROXY-1-PROPENYL)-2-METHOXY-
    • 2-PROPEN-1-OL, 3-(4-HYDROXY-3-METHOXYPHENYL)-, (E)-
    • 4-hydroxy-3-methoxy cinnamyl alcohol
    • AI3-36149
    • 4-[3-Hydroxy-1-propenyl]-2-methoxyphenol
    • 4-((1E)-3-hydroxyprop-1-en-1-yl)-2-methoxyphenol
    • DTXSID9060029
    • Coniferyl?alcohol
    • CONIFERYL-ALCOHOL
    • Coniferyl Alcohol1512
    • epsilon-coniferyl alcohol
    • 4-(3-hydroxyprop-1-enyl)-2-methoxyphenol
    • Coniferyl alcohol, 98%
    • Coniferyl Alcohol Phenolic
    • bmse000602
    • bmse010248
    • bmse010285
    • Epitope ID:116871
    • SCHEMBL177683
    • CHEMBL501870
    • DTXCID7040447
    • HY-N4283A
    • DTXSID50186489
    • 4e70
    • HBA81140
    • HY-N4283
    • AKOS005258118
    • FC69901
    • PS-4366
    • AC-34753
    • DB-342518
    • 4-(3-hydroxy-1-propenyl)-2-methoxy-Phenol
    • CS-0032634
    • NS00031560
    • S6429
    • C00590
    • D93191
    • EN300-1857771
    • EN300-6472482
    • (E)-4-(3 -hydroxyprop-1-enyl)-2-methoxyphenol
    • 4-[(E)-3-hydroxyprop-1-enyl]-2-methoxy-phenol
    • Q418993
    • (E) 3-(4-hydroxy-3-methoxyphenyl)-2-Propen-1-ol
    • (E)-4-(3-Hydroxyprop-1-en-1-yl)-2-methoxyphenol
    • F8420572-6986-4EF3-917B-3298FD384F2C
    • 207-277-9

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 273.4
    methanol 367.0
    isopropanol 152.23
    water 1.57
    ethyl acetate 220.23
    n-propanol 175.15
    acetone 312.16
    n-butanol 104.68
    acetonitrile 172.16
    DMF 382.45
    toluene 20.07
    isobutanol 86.96
    1,4-dioxane 425.73
    methyl acetate 249.43
    THF 481.25
    2-butanone 155.77
    n-pentanol 74.39
    sec-butanol 102.81
    n-hexane 1.91
    ethylene glycol 249.81
    NMP 169.47
    cyclohexane 4.72
    DMSO 931.92
    n-butyl acetate 72.49
    n-octanol 38.58
    chloroform 103.73
    n-propyl acetate 105.13
    acetic acid 348.09
    dichloromethane 133.42
    cyclohexanone 139.77
    propylene glycol 217.58
    isopropyl acetate 74.5
    DMAc 251.64
    2-ethoxyethanol 292.03
    isopentanol 83.97
    n-heptane 4.08
    ethyl formate 120.75
    1,2-dichloroethane 136.09
    n-hexanol 75.18
    2-methoxyethanol 484.43
    isobutyl acetate 53.37
    tetrachloromethane 16.44
    n-pentyl acetate 39.15
    transcutol 412.51
    n-heptanol 40.83
    ethylbenzene 16.83
    MIBK 73.84
    2-propoxyethanol 173.01
    tert-butanol 404.65
    MTBE 143.51
    2-butoxyethanol 94.22
    propionic acid 183.43
    o-xylene 21.91
    formic acid 255.64
    diethyl ether 111.12
    m-xylene 22.33
    p-xylene 19.25
    chlorobenzene 36.24
    dimethyl carbonate 95.78
    n-octane 2.75
    formamide 480.27
    cyclopentanone 233.71
    2-pentanone 119.31
    anisole 80.24
    cyclopentyl methyl ether 106.59
    gamma-butyrolactone 322.11
    1-methoxy-2-propanol 261.81
    pyridine 108.41
    3-pentanone 73.07
    furfural 220.47
    n-dodecane 3.3
    diethylene glycol 250.96
    diisopropyl ether 24.44
    tert-amyl alcohol 189.98
    acetylacetone 172.2
    n-hexadecane 3.55
    acetophenone 70.92
    methyl propionate 159.76
    isopentyl acetate 62.91
    trichloroethylene 204.21
    n-nonanol 34.82
    cyclohexanol 81.56
    benzyl alcohol 76.54
    2-ethylhexanol 40.64
    isooctanol 33.79
    dipropyl ether 40.68
    1,2-dichlorobenzene 41.06
    ethyl lactate 72.45
    propylene carbonate 134.32
    n-methylformamide 268.86
    2-pentanol 66.17
    n-pentane 2.05
    1-propoxy-2-propanol 105.76
    1-methoxy-2-propyl acetate 92.21
    2-(2-methoxypropoxy) propanol 100.27
    mesitylene 17.79
    ε-caprolactone 128.39
    p-cymene 18.0
    epichlorohydrin 341.54
    1,1,1-trichloroethane 80.36
    2-aminoethanol 272.46
    morpholine-4-carbaldehyde 244.06
    sulfolane 367.86
    2,2,4-trimethylpentane 4.29
    2-methyltetrahydrofuran 184.72
    n-hexyl acetate 57.34
    isooctane 3.71
    2-(2-butoxyethoxy)ethanol 138.51
    sec-butyl acetate 54.71
    tert-butyl acetate 101.76
    decalin 4.83
    glycerin 321.66
    diglyme 253.34
    acrylic acid 176.3
    isopropyl myristate 27.52
    n-butyric acid 167.35
    acetyl acetate 96.04
    di(2-ethylhexyl) phthalate 30.58
    ethyl propionate 80.2
    nitromethane 570.84
    1,2-diethoxyethane 95.16
    benzonitrile 60.19
    trioctyl phosphate 26.63
    1-bromopropane 38.71
    gamma-valerolactone 265.4
    n-decanol 28.41
    triethyl phosphate 38.69
    4-methyl-2-pentanol 42.66
    propionitrile 102.01
    vinylene carbonate 119.01
    1,1,2-trichlorotrifluoroethane 269.35
    DMS 67.03
    cumene 16.01
    2-octanol 26.42
    2-hexanone 75.79
    octyl acetate 34.65
    limonene 25.62
    1,2-dimethoxyethane 298.59
    ethyl orthosilicate 36.69
    tributyl phosphate 29.39
    diacetone alcohol 163.27
    N,N-dimethylaniline 49.02
    acrylonitrile 150.4
    aniline 66.2
    1,3-propanediol 273.51
    bromobenzene 28.87
    dibromomethane 72.29
    1,1,2,2-tetrachloroethane 159.07
    2-methyl-cyclohexyl acetate 49.13
    tetrabutyl urea 40.03
    diisobutyl methanol 30.27
    2-phenylethanol 63.57
    styrene 21.32
    dioctyl adipate 43.54
    dimethyl sulfate 161.92
    ethyl butyrate 57.36
    methyl lactate 117.76
    butyl lactate 46.56
    diethyl carbonate 48.3
    propanediol butyl ether 94.74
    triethyl orthoformate 46.09
    p-tert-butyltoluene 19.25
    methyl 4-tert-butylbenzoate 68.76
    morpholine 409.52
    tert-butylamine 123.99
    n-dodecanol 23.62
    dimethoxymethane 281.97
    ethylene carbonate 101.53
    cyrene 107.73
    2-ethoxyethyl acetate 75.6
    2-ethylhexyl acetate 42.88
    1,2,4-trichlorobenzene 52.81
    4-methylpyridine 75.0
    dibutyl ether 35.17
    2,6-dimethyl-4-heptanol 30.27
    DEF 117.26
    dimethyl isosorbide 141.4
    tetrachloroethylene 98.87
    eugenol 77.18
    triacetin 76.99
    span 80 74.42
    1,4-butanediol 115.45
    1,1-dichloroethane 89.82
    2-methyl-1-pentanol 63.1
    methyl formate 241.47
    2-methyl-1-butanol 72.87
    n-decane 4.46
    butyronitrile 73.49
    3,7-dimethyl-1-octanol 37.83
    1-chlorooctane 20.22
    1-chlorotetradecane 9.81
    n-nonane 4.01
    undecane 3.74
    tert-butylcyclohexane 5.02
    cyclooctane 2.5
    cyclopentanol 102.75
    tetrahydropyran 182.94
    tert-amyl methyl ether 83.92
    2,5,8-trioxanonane 179.85
    1-hexene 10.38
    2-isopropoxyethanol 162.59
    2,2,2-trifluoroethanol 138.84
    methyl butyrate 104.02

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Oregano, spanish (Israel) 4 8007-11-2 Coridothymus capitatus Rchb. (Thymus capitatus Hoffm. et Link.), Lamiaceae 0.3%