Coenzyme Q2

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  • Identifiers

    CAS number
    606-06-4

    Molecular formula
    C19H26O4

    SMILES
    CC1=C(C(=O)C(=C(C1=O)OC)OC)C/C=C(\C)/CCC=C(C)C

    Safety labels

  • Odor profile

    Fragrance
    Fruity 70.63%
    Floral 56.44%
    Sweet 54.14%
    Woody 44.07%
    Spicy 39.92%
    Herbal 39.67%
    Rose 34.72%
    Citrus 33.33%
    Dry 31.88%
    Caramellic 30.8%

     

    Flavor
    Herbal 42.99%
    Spicy 34.86%
    Minty 29.43%
    Woody 26.64%
    Celery 23.48%
    Bitter 21.87%
    Spice 21.81%
    Outdoor 21.19%
    Basil 20.77%
    Genet 20.7%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    4.6

    pKa est.
    6.8 (neutral)

    Molecular weight
    318.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    390°C

    Flash point

    • 163.72 ˚C est.

  • Synonyms

    • Coenzyme Q2
    • Ubiquinone-2
    • Ubiquinone Q2
    • 606-06-4
    • I7T5V2W47R
    • 2,3-Dimethoxy-5-geranyl-6-methyl-1,4-benzoquinone
    • 2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
    • 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
    • CHEBI:46372
    • DTXSID001019698
    • p-benzoquinone, 2-geranyl-5,6-dimethoxy-3-methyl-
    • (E)-2-(3,7-Dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-p-benzoquinone
    • 2,5-Cyclohexadiene-1,4-dione, 2-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-
    • 2,5-cyclohexadiene-1,4-dione, 2-((2e)-3,7-dimethyl-2,6-octadien-1-yl)-5,6-dimethoxy-3-methyl-
    • 2-((2E)-3,7-dimethylocta-2,6-dien-1-yl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
    • 2-((2E)-3,7-dimethylocta-2,6-dienyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
    • RefChem:900963
    • DTXCID80909128
    • Ubiquinone 2
    • UBIQUINONES
    • 2-(3,7-Dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione
    • p-Benzoquinone, 2-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-, (E)-
    • 7704-04-3
    • Q 2
    • UNII-I7T5V2W47R
    • 1339-63-5
    • Coenzyme Q2, >=90%
    • SCHEMBL623496
    • CHEMBL1236595
    • MFCD00871693
    • MSK178271
    • AKOS040755055
    • AT47632
    • DB08690
    • CoQ8, Coenzyme Q8 (E. coli), powder
    • HY-118075
    • COENZYME Q2 (A SOLUTION IN ETHANOL)
    • CS-0065140
    • NS00014814
    • C00399
    • dimethoxy-5-methyl-6-geranyl-1,4-benzoquinone
    • 2,3-Dimethoxy-5-methyl-6-geranyl-1,4-benzoquinone
    • Q27097878
    • 2-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl- p-Benzoquinone
    • 2-[(2E)-3,7-Dimethyl-2,6-octadienyl]-5,6-dimethoxy-3-methyl- p-Benzoquinone
    • 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-5,6-dimethoxy-3-methyl-1,4-benzoquinone
    • 2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5,6-dimethoxy-3-methyl-1,4-benzoquinone
    • 606-06-4

  • Applications

    Coenzyme Q2 (CAS 606-06-4) is applied primarily as an antioxidant and stabilizer in cosmetics and personal care formulations, helping protect ingredients and extend shelf life; it is also used as a stabilizer and redox-active additive in polymers/plastics, coatings, and inks to improve durability and aging resistance. In research and pharmaceutical development, Coenzyme Q2 is commonly used as a model biological cofactor and as a substrate for redox studies and the synthesis of ubiquinone derivatives. Additionally, due to its redox properties, it can serve as a redox mediator or analytical reagent in electrochemical analysis and biosensor applications, supporting sensor design and related analytical methods.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 58.76
    methanol 37.77
    isopropanol 55.74
    water 0.02
    ethyl acetate 181.99
    n-propanol 81.98
    acetone 195.63
    n-butanol 80.76
    acetonitrile 89.03
    DMF 221.78
    toluene 172.03
    isobutanol 65.84
    1,4-dioxane 246.15
    methyl acetate 184.85
    THF 386.09
    2-butanone 257.3
    n-pentanol 75.5
    sec-butanol 93.86
    n-hexane 8.4
    ethylene glycol 6.26
    NMP 347.95
    cyclohexane 25.67
    DMSO 124.33
    n-butyl acetate 100.3
    n-octanol 26.09
    chloroform 635.93
    n-propyl acetate 106.45
    acetic acid 97.7
    dichloromethane 606.55
    cyclohexanone 390.05
    propylene glycol 16.64
    isopropyl acetate 98.08
    DMAc 279.0
    2-ethoxyethanol 108.96
    isopentanol 73.57
    n-heptane 3.96
    ethyl formate 83.64
    1,2-dichloroethane 402.58
    n-hexanol 69.24
    2-methoxyethanol 122.14
    isobutyl acetate 64.65
    tetrachloromethane 78.55
    n-pentyl acetate 83.47
    transcutol 185.5
    n-heptanol 41.29
    ethylbenzene 78.16
    MIBK 90.83
    2-propoxyethanol 120.4
    tert-butanol 74.0
    MTBE 82.57
    2-butoxyethanol 85.23
    propionic acid 80.08
    o-xylene 98.37
    formic acid 18.37
    diethyl ether 108.98
    m-xylene 96.28
    p-xylene 98.55
    chlorobenzene 238.31
    dimethyl carbonate 69.21
    n-octane 2.71
    formamide 45.97
    cyclopentanone 413.44
    2-pentanone 186.91
    anisole 128.28
    cyclopentyl methyl ether 194.49
    gamma-butyrolactone 362.01
    1-methoxy-2-propanol 107.36
    pyridine 378.16
    3-pentanone 171.6
    furfural 294.15
    n-dodecane 1.9
    diethylene glycol 59.69
    diisopropyl ether 29.07
    tert-amyl alcohol 91.6
    acetylacetone 175.55
    n-hexadecane 2.33
    acetophenone 150.53
    methyl propionate 173.08
    isopentyl acetate 93.75
    trichloroethylene 832.95
    n-nonanol 28.44
    cyclohexanol 147.23
    benzyl alcohol 127.31
    2-ethylhexanol 47.46
    isooctanol 36.6
    dipropyl ether 38.15
    1,2-dichlorobenzene 197.15
    ethyl lactate 52.8
    propylene carbonate 174.71
    n-methylformamide 87.86
    2-pentanol 67.01
    n-pentane 7.98
    1-propoxy-2-propanol 78.73
    1-methoxy-2-propyl acetate 99.22
    2-(2-methoxypropoxy) propanol 68.81
    mesitylene 48.9
    ε-caprolactone 292.81
    p-cymene 34.78
    epichlorohydrin 505.83
    1,1,1-trichloroethane 350.31
    2-aminoethanol 22.75
    morpholine-4-carbaldehyde 264.65
    sulfolane 336.7
    2,2,4-trimethylpentane 6.98
    2-methyltetrahydrofuran 321.11
    n-hexyl acetate 88.27
    isooctane 4.03
    2-(2-butoxyethoxy)ethanol 84.58
    sec-butyl acetate 76.99
    tert-butyl acetate 100.6
    decalin 14.07
    glycerin 24.04
    diglyme 170.57
    acrylic acid 70.26
    isopropyl myristate 28.88
    n-butyric acid 121.91
    acetyl acetate 97.8
    di(2-ethylhexyl) phthalate 40.33
    ethyl propionate 103.07
    nitromethane 202.43
    1,2-diethoxyethane 81.54
    benzonitrile 131.41
    trioctyl phosphate 25.03
    1-bromopropane 191.25
    gamma-valerolactone 399.29
    n-decanol 20.32
    triethyl phosphate 43.89
    4-methyl-2-pentanol 36.45
    propionitrile 103.26
    vinylene carbonate 144.54
    1,1,2-trichlorotrifluoroethane 249.14
    DMS 94.43
    cumene 45.27
    2-octanol 28.47
    2-hexanone 117.93
    octyl acetate 40.84
    limonene 45.95
    1,2-dimethoxyethane 158.72
    ethyl orthosilicate 42.08
    tributyl phosphate 29.08
    diacetone alcohol 112.67
    N,N-dimethylaniline 83.43
    acrylonitrile 126.52
    aniline 182.65
    1,3-propanediol 48.64
    bromobenzene 245.95
    dibromomethane 383.35
    1,1,2,2-tetrachloroethane 625.18
    2-methyl-cyclohexyl acetate 81.93
    tetrabutyl urea 41.5
    diisobutyl methanol 24.23
    2-phenylethanol 111.21
    styrene 91.67
    dioctyl adipate 49.22
    dimethyl sulfate 105.13
    ethyl butyrate 74.49
    methyl lactate 60.93
    butyl lactate 59.78
    diethyl carbonate 51.7
    propanediol butyl ether 55.13
    triethyl orthoformate 52.47
    p-tert-butyltoluene 31.96
    methyl 4-tert-butylbenzoate 89.84
    morpholine 328.62
    tert-butylamine 42.94
    n-dodecanol 14.53
    dimethoxymethane 144.97
    ethylene carbonate 120.9
    cyrene 116.64
    2-ethoxyethyl acetate 115.05
    2-ethylhexyl acetate 80.55
    1,2,4-trichlorobenzene 244.51
    4-methylpyridine 316.05
    dibutyl ether 31.01
    2,6-dimethyl-4-heptanol 24.23
    DEF 185.52
    dimethyl isosorbide 152.98
    tetrachloroethylene 354.42
    eugenol 92.36
    triacetin 87.04
    span 80 60.31
    1,4-butanediol 26.17
    1,1-dichloroethane 346.14
    2-methyl-1-pentanol 83.27
    methyl formate 78.65
    2-methyl-1-butanol 88.32
    n-decane 3.62
    butyronitrile 100.11
    3,7-dimethyl-1-octanol 30.39
    1-chlorooctane 24.66
    1-chlorotetradecane 8.83
    n-nonane 3.07
    undecane 2.5
    tert-butylcyclohexane 10.33
    cyclooctane 6.97
    cyclopentanol 144.13
    tetrahydropyran 307.82
    tert-amyl methyl ether 81.71
    2,5,8-trioxanonane 107.04
    1-hexene 38.63
    2-isopropoxyethanol 90.68
    2,2,2-trifluoroethanol 39.67
    methyl butyrate 130.05

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction