Civetone

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    542-46-1

    Molecular formula
    C17H30O

    SMILES
    C1CCC/C=C\CCCCCCCC(=O)CCC1

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Musk 91.64%
    Animal 65.92%
    Powdery 64.86%
    Amber 52.22%
    Dry 46.89%
    Natural 41.25%
    Clean 39.04%
    Sweet 37.7%
    Balsamic 34.77%
    Waxy 33.91%

     

    Flavor
    Animal 31.23%
    Fruity 23.85%
    Shrimp 22.08%
    Ammoniacal 21.09%
    Minty 21.06%
    Camphor 20.66%
    Alkaline 20.17%
    Musk 19.42%
    Beet 19.23%
    Soil 19.01%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    6.1

    pKa est.
    9.42 (weak base)

    Molecular weight
    250.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    340°C

    Flash point

    • 155.33 ˚C est.

    Solubility expt.

    • Soluble in oils; Slightly soluble in water
    • Soluble (in ethanol)

  • Synonyms

    • Civetone
    • cis-Civetone
    • 542-46-1
    • (9Z)-cycloheptadec-9-en-1-one
    • (Z)-Cycloheptadec-9-enone
    • 9-Cycloheptadecen-1-one, (Z)-
    • 9-Cycloheptadecen-1-one, (9Z)-
    • Civettone, alpha-trans-
    • FEMA No. 3425
    • cycloheptadeca-9-en-1-one
    • 9-Cycloheptadecen-1-one, cis-
    • UNII-P0K30CV1UE
    • EINECS 208-813-4
    • NSC 90305
    • 9-CYCLOHEPTADECEN-1-ONE
    • BRN 1954923
    • AI3-38745
    • 74244-64-7
    • CIVETONE [MI]
    • P0K30CV1UE
    • Zibeton
    • CHEBI:78317
    • DTXSID80883434
    • 3-07-00-00524 (Beilstein Handbook Reference)
    • (9Z)-9-CYCLOHEPTADECENE-1-ONE
    • CYCLOHEPTADECA-9-EN-1-ONE, CIS-
    • CYCLOHEPTADECA-9-EN-1-ONE [FHFI]
    • cis-9-Cycloheptadecen-1-one
    • NSC-90305
    • CIVETTONE
    • Cycloheptadenen-9-one-1
    • SCHEMBL284379
    • DTXCID60212728
    • NSC90305
    • Q198354
    • 208-813-4

  • Applications

    Civetone, CAS 542-46-1, is a macrocyclic ketone known as a musk fragrance ingredient used in perfumery. It is commonly used as a musk note and a fixative to prolong scent in fragrance formulations. In cosmetics/personal care, civetone is incorporated into formulations for skincare and cosmetic products to deliver a characteristic musk aroma. In household cleaning products, it may be used to impart musk notes in detergents and cleaners. Additionally, civetone can be considered as a fragrance formulation additive in industrial manufacturing to enhance fragrance longevity.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 159.5
    methanol 89.46
    isopropanol 213.31
    water 0.01
    ethyl acetate 864.36
    n-propanol 225.25
    acetone 719.65
    n-butanol 279.9
    acetonitrile 278.2
    DMF 720.14
    toluene 664.2
    isobutanol 214.57
    1,4-dioxane 952.91
    methyl acetate 492.9
    THF 1822.43
    2-butanone 718.33
    n-pentanol 205.44
    sec-butanol 256.87
    n-hexane 286.33
    ethylene glycol 12.19
    NMP 980.38
    cyclohexane 676.17
    DMSO 673.23
    n-butyl acetate 878.67
    n-octanol 184.11
    chloroform 2345.55
    n-propyl acetate 702.41
    acetic acid 210.92
    dichloromethane 2093.77
    cyclohexanone 1607.18
    propylene glycol 40.31
    isopropyl acetate 737.4
    DMAc 728.49
    2-ethoxyethanol 254.84
    isopentanol 328.69
    n-heptane 262.23
    ethyl formate 312.49
    1,2-dichloroethane 1398.93
    n-hexanol 291.62
    2-methoxyethanol 341.86
    isobutyl acetate 501.47
    tetrachloromethane 406.23
    n-pentyl acetate 719.38
    transcutol 1839.3
    n-heptanol 174.48
    ethylbenzene 381.93
    MIBK 620.39
    2-propoxyethanol 418.39
    tert-butanol 351.94
    MTBE 625.1
    2-butoxyethanol 356.25
    propionic acid 244.04
    o-xylene 412.04
    formic acid 24.54
    diethyl ether 801.18
    m-xylene 428.94
    p-xylene 471.04
    chlorobenzene 860.18
    dimethyl carbonate 204.13
    n-octane 80.44
    formamide 55.42
    cyclopentanone 1593.39
    2-pentanone 868.56
    anisole 552.33
    cyclopentyl methyl ether 1127.88
    gamma-butyrolactone 1405.86
    1-methoxy-2-propanol 400.5
    pyridine 1193.98
    3-pentanone 699.11
    furfural 1030.99
    n-dodecane 42.1
    diethylene glycol 154.58
    diisopropyl ether 389.3
    tert-amyl alcohol 328.53
    acetylacetone 927.83
    n-hexadecane 52.44
    acetophenone 561.83
    methyl propionate 554.02
    isopentyl acetate 768.54
    trichloroethylene 2312.44
    n-nonanol 190.74
    cyclohexanol 528.2
    benzyl alcohol 315.06
    2-ethylhexanol 312.61
    isooctanol 188.39
    dipropyl ether 837.98
    1,2-dichlorobenzene 843.18
    ethyl lactate 219.76
    propylene carbonate 831.33
    n-methylformamide 186.39
    2-pentanol 292.07
    n-pentane 184.34
    1-propoxy-2-propanol 477.7
    1-methoxy-2-propyl acetate 665.18
    2-(2-methoxypropoxy) propanol 379.84
    mesitylene 317.87
    ε-caprolactone 1175.82
    p-cymene 263.51
    epichlorohydrin 1418.13
    1,1,1-trichloroethane 1471.17
    2-aminoethanol 49.56
    morpholine-4-carbaldehyde 864.06
    sulfolane 1604.02
    2,2,4-trimethylpentane 85.25
    2-methyltetrahydrofuran 1328.17
    n-hexyl acetate 755.8
    isooctane 76.04
    2-(2-butoxyethoxy)ethanol 546.67
    sec-butyl acetate 546.19
    tert-butyl acetate 770.0
    decalin 223.63
    glycerin 65.53
    diglyme 1080.94
    acrylic acid 175.9
    isopropyl myristate 323.98
    n-butyric acid 596.77
    acetyl acetate 526.59
    di(2-ethylhexyl) phthalate 210.7
    ethyl propionate 626.04
    nitromethane 466.94
    1,2-diethoxyethane 978.84
    benzonitrile 550.67
    trioctyl phosphate 163.91
    1-bromopropane 978.49
    gamma-valerolactone 1501.85
    n-decanol 138.58
    triethyl phosphate 323.44
    4-methyl-2-pentanol 212.83
    propionitrile 409.06
    vinylene carbonate 623.32
    1,1,2-trichlorotrifluoroethane 788.13
    DMS 486.3
    cumene 250.87
    2-octanol 160.37
    2-hexanone 628.2
    octyl acetate 356.02
    limonene 450.72
    1,2-dimethoxyethane 765.78
    ethyl orthosilicate 318.87
    tributyl phosphate 234.81
    diacetone alcohol 527.0
    N,N-dimethylaniline 377.83
    acrylonitrile 408.04
    aniline 508.35
    1,3-propanediol 124.24
    bromobenzene 1092.18
    dibromomethane 1492.92
    1,1,2,2-tetrachloroethane 2093.38
    2-methyl-cyclohexyl acetate 530.52
    tetrabutyl urea 301.01
    diisobutyl methanol 257.73
    2-phenylethanol 314.2
    styrene 494.42
    dioctyl adipate 447.4
    dimethyl sulfate 339.77
    ethyl butyrate 765.59
    methyl lactate 183.65
    butyl lactate 385.79
    diethyl carbonate 446.05
    propanediol butyl ether 280.43
    triethyl orthoformate 542.12
    p-tert-butyltoluene 245.82
    methyl 4-tert-butylbenzoate 504.9
    morpholine 1052.59
    tert-butylamine 298.24
    n-dodecanol 111.84
    dimethoxymethane 520.89
    ethylene carbonate 608.9
    cyrene 327.54
    2-ethoxyethyl acetate 691.7
    2-ethylhexyl acetate 655.77
    1,2,4-trichlorobenzene 919.74
    4-methylpyridine 1082.53
    dibutyl ether 715.87
    2,6-dimethyl-4-heptanol 257.73
    DEF 871.63
    dimethyl isosorbide 741.93
    tetrachloroethylene 1296.54
    eugenol 362.05
    triacetin 679.31
    span 80 409.37
    1,4-butanediol 47.38
    1,1-dichloroethane 1307.14
    2-methyl-1-pentanol 237.42
    methyl formate 158.38
    2-methyl-1-butanol 284.57
    n-decane 88.77
    butyronitrile 527.86
    3,7-dimethyl-1-octanol 262.17
    1-chlorooctane 319.53
    1-chlorotetradecane 118.68
    n-nonane 93.94
    undecane 57.08
    tert-butylcyclohexane 161.99
    cyclooctane 226.76
    cyclopentanol 442.28
    tetrahydropyran 1508.15
    tert-amyl methyl ether 540.54
    2,5,8-trioxanonane 688.66
    1-hexene 515.81
    2-isopropoxyethanol 267.31
    2,2,2-trifluoroethanol 83.89
    methyl butyrate 803.42

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Civet secretion (China) 68916-26-7 Viverra zibetha L., fam. Viverridae 16.84%