Cinnamido benzylpiperidinyl ethoxypropylbenzamide

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  • Identifiers

    CAS number
    1382749-08-7

    Molecular formula
    C33H39N3O3

    SMILES
    CCOCCCNC(=O)C1=C(C=CC(=C1)NC(=O)/C=C/C2=CC=CC=C2)N3CCC(CC3)CC4=CC=CC=C4

    Safety labels

  • Odor profile

    Fragrance
    Savory 38.77%
    Meaty 36.4%
    Fruity 34.34%
    Odorless 31.57%
    Cooked 30.08%
    Grape 27.52%
    Roasted 26.29%
    Cooling 25.34%
    Animal 22.98%
    Cheesy 21.82%

     

    Flavor
    Bitter 54.99%
    Fruity 31.6%
    Odorless 30.47%
    Mild 26.09%
    Orange flower 20.04%
    Nitrile 19.98%
    Orange blossom 19.84%
    Petitgrain 19.66%
    Heather 19.4%
    Ethyl benzoate 19.31%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    5.9

    pKa est.
    7.31 (neutral)

    Molecular weight
    525.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1741°C

    Flash point

    • 296.09 ˚C est.

  • Synonyms

    • B90L76CSCY
    • Cinnamido benzylpiperidinyl ethoxypropylbenzamide
    • UNII-B90L76CSCY
    • 1382749-08-7
    • Benzamide, N-(3-ethoxypropyl)-5-(((2E)-1-oxo-3-phenyl-2-propen-1-yl)amino)-2-(4-(phenylmethyl)-1-piperidinyl)-
    • Cinnamido benzylpiperidinyl ethoxypropylbenzamide [INCI]
    • SCHEMBL9949273
    • Q27274520
    • 1382749-08-7

  • Applications

    Cinnamido benzylpiperidinyl ethoxypropylbenzamide (CAS 1382749-08-7) is primarily encountered as a synthetic intermediate in medicinal chemistry and pharmaceutical research, enabling the construction of more complex amide- and piperidine-containing compounds. In fragrance and cosmetics contexts, the compound may be evaluated as a potential odor-active ingredient or fragrance component and as a candidate fixative or carrier for active ingredients. In materials-related applications, it may be explored as a chemical building block for polymer or coating formulations, including functional monomers or cross-linkable intermediates. It can also serve as a research and development building block for specialty chemical syntheses, with use constrained by regulatory and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.35
    methanol 3.38
    isopropanol 1.35
    water 0.01
    ethyl acetate 2.58
    n-propanol 2.6
    acetone 5.67
    n-butanol 2.37
    acetonitrile 1.18
    DMF 13.37
    toluene 4.1
    isobutanol 1.65
    1,4-dioxane 4.62
    methyl acetate 3.64
    THF 18.84
    2-butanone 8.34
    n-pentanol 2.25
    sec-butanol 1.97
    n-hexane 0.06
    ethylene glycol 0.66
    NMP 25.47
    cyclohexane 0.08
    DMSO 12.94
    n-butyl acetate 2.08
    n-octanol 0.93
    chloroform 37.7
    n-propyl acetate 2.52
    acetic acid 7.49
    dichloromethane 27.96
    cyclohexanone 17.43
    propylene glycol 1.48
    isopropyl acetate 1.79
    DMAc 45.23
    2-ethoxyethanol 5.49
    isopentanol 1.65
    n-heptane 0.06
    ethyl formate 3.76
    1,2-dichloroethane 9.22
    n-hexanol 1.11
    2-methoxyethanol 6.82
    isobutyl acetate 1.79
    tetrachloromethane 2.6
    n-pentyl acetate 2.46
    transcutol 9.39
    n-heptanol 1.16
    ethylbenzene 1.15
    MIBK 2.42
    2-propoxyethanol 5.67
    tert-butanol 0.97
    MTBE 1.02
    2-butoxyethanol 4.51
    propionic acid 4.22
    o-xylene 1.65
    formic acid 4.58
    diethyl ether 1.09
    m-xylene 1.59
    p-xylene 1.49
    chlorobenzene 6.31
    dimethyl carbonate 3.44
    n-octane 0.04
    formamide 5.56
    cyclopentanone 21.21
    2-pentanone 5.01
    anisole 2.89
    cyclopentyl methyl ether 3.77
    gamma-butyrolactone 17.32
    1-methoxy-2-propanol 5.35
    pyridine 12.93
    3-pentanone 4.51
    furfural 18.33
    n-dodecane 0.04
    diethylene glycol 3.18
    diisopropyl ether 0.23
    tert-amyl alcohol 1.55
    acetylacetone 6.0
    n-hexadecane 0.04
    acetophenone 5.28
    methyl propionate 4.07
    isopentyl acetate 2.3
    trichloroethylene 34.5
    n-nonanol 1.06
    cyclohexanol 2.4
    benzyl alcohol 5.0
    2-ethylhexanol 0.82
    isooctanol 1.01
    dipropyl ether 0.97
    1,2-dichlorobenzene 5.17
    ethyl lactate 2.68
    propylene carbonate 7.86
    n-methylformamide 5.87
    2-pentanol 1.09
    n-pentane 0.05
    1-propoxy-2-propanol 3.86
    1-methoxy-2-propyl acetate 4.15
    2-(2-methoxypropoxy) propanol 5.32
    mesitylene 0.56
    ε-caprolactone 11.98
    p-cymene 0.55
    epichlorohydrin 21.82
    1,1,1-trichloroethane 7.73
    2-aminoethanol 1.74
    morpholine-4-carbaldehyde 15.21
    sulfolane 24.49
    2,2,4-trimethylpentane 0.05
    2-methyltetrahydrofuran 5.85
    n-hexyl acetate 2.42
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 5.42
    sec-butyl acetate 1.72
    tert-butyl acetate 1.84
    decalin 0.08
    glycerin 3.01
    diglyme 10.1
    acrylic acid 5.13
    isopropyl myristate 0.94
    n-butyric acid 5.46
    acetyl acetate 2.46
    di(2-ethylhexyl) phthalate 2.19
    ethyl propionate 2.22
    nitromethane 9.88
    1,2-diethoxyethane 2.39
    benzonitrile 3.84
    trioctyl phosphate 1.21
    1-bromopropane 3.24
    gamma-valerolactone 28.63
    n-decanol 0.72
    triethyl phosphate 1.92
    4-methyl-2-pentanol 0.64
    propionitrile 1.87
    vinylene carbonate 8.91
    1,1,2-trichlorotrifluoroethane 26.2
    DMS 2.96
    cumene 0.65
    2-octanol 0.7
    2-hexanone 4.26
    octyl acetate 1.44
    limonene 0.68
    1,2-dimethoxyethane 7.48
    ethyl orthosilicate 1.69
    tributyl phosphate 1.51
    diacetone alcohol 4.05
    N,N-dimethylaniline 2.2
    acrylonitrile 3.05
    aniline 6.21
    1,3-propanediol 2.75
    bromobenzene 5.59
    dibromomethane 12.15
    1,1,2,2-tetrachloroethane 26.17
    2-methyl-cyclohexyl acetate 2.56
    tetrabutyl urea 2.53
    diisobutyl methanol 0.42
    2-phenylethanol 3.28
    styrene 1.56
    dioctyl adipate 2.19
    dimethyl sulfate 7.46
    ethyl butyrate 2.11
    methyl lactate 4.31
    butyl lactate 3.38
    diethyl carbonate 1.53
    propanediol butyl ether 3.68
    triethyl orthoformate 2.23
    p-tert-butyltoluene 0.47
    methyl 4-tert-butylbenzoate 4.85
    morpholine 7.88
    tert-butylamine 0.41
    n-dodecanol 0.48
    dimethoxymethane 7.35
    ethylene carbonate 6.06
    cyrene 8.77
    2-ethoxyethyl acetate 4.63
    2-ethylhexyl acetate 1.93
    1,2,4-trichlorobenzene 7.94
    4-methylpyridine 10.51
    dibutyl ether 0.84
    2,6-dimethyl-4-heptanol 0.42
    DEF 6.53
    dimethyl isosorbide 8.11
    tetrachloroethylene 15.52
    eugenol 5.05
    triacetin 4.38
    span 80 4.12
    1,4-butanediol 1.54
    1,1-dichloroethane 8.5
    2-methyl-1-pentanol 2.02
    methyl formate 5.16
    2-methyl-1-butanol 2.1
    n-decane 0.07
    butyronitrile 2.01
    3,7-dimethyl-1-octanol 0.88
    1-chlorooctane 0.52
    1-chlorotetradecane 0.19
    n-nonane 0.06
    undecane 0.05
    tert-butylcyclohexane 0.06
    cyclooctane 0.03
    cyclopentanol 3.21
    tetrahydropyran 4.59
    tert-amyl methyl ether 1.36
    2,5,8-trioxanonane 7.11
    1-hexene 0.45
    2-isopropoxyethanol 3.65
    2,2,2-trifluoroethanol 4.03
    methyl butyrate 3.6

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction