Cinnamaldehyde oxime

Overview IFRA Request a quote

  • Identifiers

    CAS number
    13372-81-1

    Molecular formula
    C9H9NO

    SMILES
    C1=CC=C(C=C1)/C=C/C=N/O

    Safety labels

    Acute Toxic
    Acute Toxic

  • Odor profile

    Fragrance
    Spicy 56.73%
    Green 47.08%
    Cinnamon 40.57%
    Pungent 40.39%
    Radish 37.24%
    Sweet 33.46%
    Vegetable 32.11%
    Warm 21.98%
    Herbal 21.72%
    Sulfurous 21.43%

     

    Flavor
    Sweet 64.06%
    Cinnamon 52.03%
    Balsam 41.1%
    Bitter 38.11%
    Spicy 32.4%
    Honey 31.55%
    Spice 29.65%
    Floral 29.25%
    Green 28.13%
    Oily 27.08%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.2

    pKa est.
    8.2 (weak base)

    Molecular weight
    147.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    262°C

    Flash point

    • 138.36 ˚C est.

  • Synonyms

    • Cinnamaldehyde oxime
    • 13372-81-1
    • cinnamaldoxime
    • EINECS 236-449-6
    • 2-Propenal, 3-phenyl-, oxime
    • NSC 77420
    • RefChem:126248
    • 236-449-6
    • RUQDOYIAKHIMAN-DAAQNPAKSA-N
    • MFCD00019969
    • (NE)-N-[(E)-3-phenylprop-2-enylidene]hydroxylamine
    • 59336-59-3
    • N-(3-phenylprop-2-en-1-ylidene)hydroxylamine
    • 3-Phenyl-2-propenal oxime
    • Cinnamaldoxime, (E)+(Z)
    • 20707-70-4
    • (E)-N-[(2E)-3-phenylprop-2-en-1-ylidene]hydroxylamine
    • CHEMBL589874
    • SCHEMBL6124740
    • NSC47500
    • NSC77420
    • (E,1E)-3-phenylprop-2-enal oxime
    • NSC-47500
    • NSC-77420
    • AKOS000304434
    • PS-3136
    • BP-12398
    • (2E)-1-(hydroxyimino)-3-phenylprop-2-ene
    • NS00086850
    • ST50410290
    • G72431
    • doi:10.14272/RUQDOYIAKHIMAN-DAAQNPAKSA-N.1
    • 13372-81-1

  • Applications

    Cinnamaldehyde oxime (CAS 13372-81-1) is primarily used as an intermediate in organic synthesis to prepare oxime derivatives and related heterocycles; it is also evaluated for fragrance applications as a cinnamaldehyde-based odorant or fragrance intermediate; in polymer science it serves as a building block for oxime-containing polymers or crosslinking chemistries; in coatings and inks it can function as a chemical intermediate contributing to specialty formulations; in industrial manufacturing and R&D settings it is commonly used as a starting point for developing novel specialty chemicals; usage is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 238.57
    methanol 225.36
    isopropanol 117.48
    water 0.09
    ethyl acetate 431.39
    n-propanol 176.57
    acetone 840.31
    n-butanol 119.17
    acetonitrile 229.52
    DMF 972.62
    toluene 165.14
    isobutanol 98.62
    1,4-dioxane 394.43
    methyl acetate 417.67
    THF 878.58
    2-butanone 615.55
    n-pentanol 105.47
    sec-butanol 112.62
    n-hexane 8.0
    ethylene glycol 80.68
    NMP 848.17
    cyclohexane 6.33
    DMSO 2750.14
    n-butyl acetate 227.75
    n-octanol 34.58
    chloroform 307.83
    n-propyl acetate 227.36
    acetic acid 237.74
    dichloromethane 438.98
    cyclohexanone 500.45
    propylene glycol 119.46
    isopropyl acetate 200.87
    DMAc 708.9
    2-ethoxyethanol 278.07
    isopentanol 103.29
    n-heptane 7.56
    ethyl formate 150.52
    1,2-dichloroethane 568.64
    n-hexanol 102.05
    2-methoxyethanol 449.94
    isobutyl acetate 116.36
    tetrachloromethane 36.2
    n-pentyl acetate 85.99
    transcutol 2213.98
    n-heptanol 37.21
    ethylbenzene 74.35
    MIBK 205.58
    2-propoxyethanol 262.76
    tert-butanol 148.82
    MTBE 187.81
    2-butoxyethanol 123.79
    propionic acid 229.22
    o-xylene 88.72
    formic acid 91.92
    diethyl ether 229.41
    m-xylene 110.13
    p-xylene 73.81
    chlorobenzene 209.47
    dimethyl carbonate 197.46
    n-octane 2.02
    formamide 318.04
    cyclopentanone 1045.6
    2-pentanone 444.27
    anisole 246.54
    cyclopentyl methyl ether 400.51
    gamma-butyrolactone 1114.72
    1-methoxy-2-propanol 341.32
    pyridine 561.44
    3-pentanone 318.84
    furfural 606.41
    n-dodecane 1.76
    diethylene glycol 215.33
    diisopropyl ether 60.46
    tert-amyl alcohol 129.64
    acetylacetone 534.65
    n-hexadecane 2.14
    acetophenone 223.61
    methyl propionate 453.17
    isopentyl acetate 186.19
    trichloroethylene 1062.53
    n-nonanol 32.6
    cyclohexanol 102.99
    benzyl alcohol 159.46
    2-ethylhexanol 69.21
    isooctanol 33.06
    dipropyl ether 127.82
    1,2-dichlorobenzene 183.23
    ethyl lactate 94.77
    propylene carbonate 350.4
    n-methylformamide 479.6
    2-pentanol 85.18
    n-pentane 4.99
    1-propoxy-2-propanol 199.41
    1-methoxy-2-propyl acetate 267.6
    2-(2-methoxypropoxy) propanol 190.73
    mesitylene 55.47
    ε-caprolactone 389.39
    p-cymene 40.21
    epichlorohydrin 1156.8
    1,1,1-trichloroethane 289.71
    2-aminoethanol 148.19
    morpholine-4-carbaldehyde 633.94
    sulfolane 1506.63
    2,2,4-trimethylpentane 6.2
    2-methyltetrahydrofuran 631.46
    n-hexyl acetate 141.53
    isooctane 5.61
    2-(2-butoxyethoxy)ethanol 302.2
    sec-butyl acetate 141.43
    tert-butyl acetate 239.16
    decalin 10.96
    glycerin 175.61
    diglyme 588.07
    acrylic acid 228.61
    isopropyl myristate 48.54
    n-butyric acid 217.2
    acetyl acetate 183.0
    di(2-ethylhexyl) phthalate 50.49
    ethyl propionate 210.25
    nitromethane 857.6
    1,2-diethoxyethane 354.92
    benzonitrile 176.97
    trioctyl phosphate 31.56
    1-bromopropane 159.64
    gamma-valerolactone 842.44
    n-decanol 24.05
    triethyl phosphate 70.85
    4-methyl-2-pentanol 54.65
    propionitrile 169.55
    vinylene carbonate 251.18
    1,1,2-trichlorotrifluoroethane 596.63
    DMS 206.6
    cumene 45.86
    2-octanol 20.93
    2-hexanone 242.5
    octyl acetate 61.91
    limonene 60.96
    1,2-dimethoxyethane 401.54
    ethyl orthosilicate 64.9
    tributyl phosphate 50.9
    diacetone alcohol 296.99
    N,N-dimethylaniline 131.43
    acrylonitrile 286.03
    aniline 259.77
    1,3-propanediol 159.25
    bromobenzene 197.12
    dibromomethane 240.5
    1,1,2,2-tetrachloroethane 729.68
    2-methyl-cyclohexyl acetate 116.41
    tetrabutyl urea 70.87
    diisobutyl methanol 43.91
    2-phenylethanol 126.17
    styrene 109.74
    dioctyl adipate 93.3
    dimethyl sulfate 449.65
    ethyl butyrate 161.1
    methyl lactate 170.73
    butyl lactate 93.69
    diethyl carbonate 103.45
    propanediol butyl ether 164.39
    triethyl orthoformate 100.9
    p-tert-butyltoluene 38.71
    methyl 4-tert-butylbenzoate 125.19
    morpholine 625.59
    tert-butylamine 75.18
    n-dodecanol 18.0
    dimethoxymethane 538.03
    ethylene carbonate 185.66
    cyrene 164.46
    2-ethoxyethyl acetate 204.82
    2-ethylhexyl acetate 143.68
    1,2,4-trichlorobenzene 256.43
    4-methylpyridine 450.85
    dibutyl ether 87.06
    2,6-dimethyl-4-heptanol 43.91
    DEF 429.67
    dimethyl isosorbide 326.85
    tetrachloroethylene 367.77
    eugenol 124.52
    triacetin 179.08
    span 80 129.8
    1,4-butanediol 66.37
    1,1-dichloroethane 322.91
    2-methyl-1-pentanol 95.05
    methyl formate 304.72
    2-methyl-1-butanol 104.16
    n-decane 2.96
    butyronitrile 136.04
    3,7-dimethyl-1-octanol 53.02
    1-chlorooctane 25.52
    1-chlorotetradecane 9.31
    n-nonane 2.69
    undecane 2.24
    tert-butylcyclohexane 11.44
    cyclooctane 3.28
    cyclopentanol 154.42
    tetrahydropyran 371.65
    tert-amyl methyl ether 153.87
    2,5,8-trioxanonane 347.53
    1-hexene 52.9
    2-isopropoxyethanol 186.39
    2,2,2-trifluoroethanol 90.55
    methyl butyrate 241.3

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction