Cholesteryl palmitoleate

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  • Identifiers

    CAS number
    16711-66-3

    Molecular formula
    C43H74O2

    SMILES
    CCCCCC/C=C\CCCCCCCC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CC[C@@H]4[C@H](C)CCCC(C)C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Waxy 60.71%
    Woody 55.49%
    Oily 45.61%
    Fatty 43.06%
    Balsamic 38.54%
    Sandalwood 35.47%
    Floral 31.94%
    Green 29.7%
    Amber 27.58%
    Sweet 27.03%

     

    Flavor
    Waxy 30.19%
    Mild 24.65%
    Faint 23.82%
    Woody 23.77%
    Bland 22.08%
    Fatty 21.32%
    Oily 21.27%
    Slightly waxy 21.19%
    Delicate 20.79%
    Diterpene 20.68%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    15.5

    pKa est.
    -10.21 (strong acid)

    Molecular weight
    623.0 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    615°C

    Flash point

    • 109.71 ˚C est.

  • Synonyms

    • Cholesteryl palmitoleate
    • 16711-66-3
    • Cholesteryl 9-hexadecenoate
    • Cholesteryl 9-palmitelaidate
    • Cholesteryl 9-palmitoleate
    • 132TTN4QMV
    • Cholesteryl cis-9-hexadecenoate
    • CHEBI:84323
    • DTXSID801312800
    • RefChem:918539
    • DTXCID801742647
    • Cholesteryl trans-9-hexadecenoate
    • Cholesterol palmitoleate
    • CHOLESTERYL PALMITOLEATE CRYSTALLINE
    • CE(16:1(9Z))
    • CE(16:1)
    • 1-palmitoleoyl-cholesterol
    • UNII-132TTN4QMV
    • Cholesteryl cis-hexadecenoate
    • 16:1(9Z) cholesterol ester
    • (Z)-Cholesterol 9-hexadecenoate
    • (Z)-Cholesterol 9-hexadecenoic acid
    • [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] (Z)-hexadec-9-enoate
    • CE(16:1n7/0:0)
    • CE(16:1w7/0:0)
    • cholest-5-en-3beta-yl (9Z-hexadecenoate)
    • CE(16:1/0:0)
    • Cholest-5-en-3-ol (3beta)-, 9-hexadecenoate, (Z)-
    • C43H74O2
    • Cholesteryl palmitoleat
    • cholesterol 1-palmitoleoate
    • cholesteryl 1-palmitoleoate
    • Cholesterol Ester(16:1)
    • Cholesteryl palmitoleic acid
    • cholesteryl (9Z)-hexadecenoate
    • cholesterol 1-palmitoleoic acid
    • cholesterol cis-9-hexadecenoate
    • cholesteryl 1-palmitoleoic acid
    • orb2283043
    • SCHEMBL22611952
    • cholesterol 1-(9Z-hexadecenoate
    • cholesteryl 1-(9Z-hexadecenoate
    • Cholesteryl cis-hexadecenoic acid
    • cholesterol 1-(9Z-hexadecenoate)
    • Cholesterol Ester(16:1/0:0)
    • cholesteryl 1-(9Z-hexadecenoate)
    • Cholesterol Ester(16:1n7/0:0)
    • Cholesterol Ester(16:1w7/0:0)
    • CHOLESTEROL, 9-HEXADECENOATE
    • cholesterol 1-(9Z-hexadecenoic acid
    • cholesteryl 1-(9Z-hexadecenoic acid
    • LMST01020006
    • MFCD00056442
    • cholesterol 1-(9Z-hexadecenoic acid)
    • cholesteryl 1-(9Z-hexadecenoic acid)
    • cholest-5-en-3beta-yl (9Z hexadecenoate
    • cholest-5-en-3beta-yl (9Z hexadecenoate)
    • HY-113086
    • CS-0059523
    • cholest-5-en-3beta-yl (9Z hexadecenoic acid
    • Cholest-5-en-3beta-yl (9Z)-hexadec-9-enoate
    • (3beta)-cholest-5-en-3-yl (9Z)-hexadec-9-enoate
    • Q27157679
    • CHOLEST-5-EN-3-OL (3.BETA.)-, 9-HEXADECENOATE
    • CHOLEST-5-EN-3-OL (3.BETA.)-, 3-(9-HEXADECENOATE)
    • CHOLEST-5-EN-3-OL (3.BETA.)-, 3-((9Z)-9-HEXADECENOATE)
    • [(3S,8S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] (Z)-hexadec-9-enoate
    • 1797-71-3
    • 16711-66-3

  • Applications

    Cholesteryl palmitoleate (CAS 16711-66-3) is a waxy lipid ester commonly used in cosmetics and personal care as an emollient and texture-building ingredient in creams and lip products, helping enhance softness, glide, and gloss. In pharmaceutical formulations, it can serve as a lipid component in lipid-based delivery systems such as liposomes or solid lipid nanoparticles, and as an excipient in certain formulations. In coatings, inks, and plastics, it may function as a wax-like additive to adjust crystallinity, melting behavior, and film formation, aiding processing and surface properties. In industrial manufacturing, it can act as a processing aid or lubricant additive, improving rheology and high-temperature stability of formulations. It may also appear in specialty waxes for coatings and polishes, depending on formulation needs.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 19.24
    methanol 7.45
    isopropanol 14.35
    water 0.05
    ethyl acetate 67.33
    n-propanol 31.25
    acetone 32.19
    n-butanol 40.67
    acetonitrile 8.66
    DMF 34.47
    toluene 106.73
    isobutanol 26.66
    1,4-dioxane 78.95
    methyl acetate 34.7
    THF 158.64
    2-butanone 68.25
    n-pentanol 34.42
    sec-butanol 23.48
    n-hexane 10.74
    ethylene glycol 0.75
    NMP 130.26
    cyclohexane 21.44
    DMSO 19.31
    n-butyl acetate 80.61
    n-octanol 22.36
    chloroform 220.36
    n-propyl acetate 58.11
    acetic acid 22.56
    dichloromethane 175.74
    cyclohexanone 166.93
    propylene glycol 2.27
    isopropyl acetate 69.91
    DMAc 109.68
    2-ethoxyethanol 37.57
    isopentanol 38.19
    n-heptane 9.63
    ethyl formate 22.14
    1,2-dichloroethane 94.65
    n-hexanol 39.72
    2-methoxyethanol 29.46
    isobutyl acetate 53.68
    tetrachloromethane 43.79
    n-pentyl acetate 95.53
    transcutol 160.42
    n-heptanol 32.83
    ethylbenzene 51.34
    MIBK 65.26
    2-propoxyethanol 78.77
    tert-butanol 12.64
    MTBE 39.88
    2-butoxyethanol 72.9
    propionic acid 23.06
    o-xylene 59.82
    formic acid 5.04
    diethyl ether 65.32
    m-xylene 63.25
    p-xylene 51.62
    chlorobenzene 114.12
    dimethyl carbonate 24.35
    n-octane 3.05
    formamide 6.72
    cyclopentanone 138.75
    2-pentanone 78.29
    anisole 74.19
    cyclopentyl methyl ether 123.45
    gamma-butyrolactone 119.38
    1-methoxy-2-propanol 39.05
    pyridine 112.66
    3-pentanone 78.86
    furfural 83.59
    n-dodecane 1.82
    diethylene glycol 17.46
    diisopropyl ether 25.9
    tert-amyl alcohol 21.28
    acetylacetone 73.39
    n-hexadecane 2.23
    acetophenone 75.06
    methyl propionate 59.01
    isopentyl acetate 91.62
    trichloroethylene 193.5
    n-nonanol 27.22
    cyclohexanol 52.48
    benzyl alcohol 45.92
    2-ethylhexanol 38.41
    isooctanol 30.91
    dipropyl ether 59.19
    1,2-dichlorobenzene 106.35
    ethyl lactate 26.61
    propylene carbonate 71.75
    n-methylformamide 15.72
    2-pentanol 28.83
    n-pentane 10.62
    1-propoxy-2-propanol 66.44
    1-methoxy-2-propyl acetate 104.67
    2-(2-methoxypropoxy) propanol 63.87
    mesitylene 37.01
    ε-caprolactone 174.43
    p-cymene 34.25
    epichlorohydrin 140.05
    1,1,1-trichloroethane 100.71
    2-aminoethanol 4.57
    morpholine-4-carbaldehyde 99.51
    sulfolane 121.74
    2,2,4-trimethylpentane 6.92
    2-methyltetrahydrofuran 142.5
    n-hexyl acetate 89.72
    isooctane 4.36
    2-(2-butoxyethoxy)ethanol 75.99
    sec-butyl acetate 59.52
    tert-butyl acetate 73.64
    decalin 12.1
    glycerin 4.42
    diglyme 142.02
    acrylic acid 16.06
    isopropyl myristate 33.48
    n-butyric acid 64.16
    acetyl acetate 50.12
    di(2-ethylhexyl) phthalate 40.06
    ethyl propionate 62.28
    nitromethane 29.04
    1,2-diethoxyethane 76.67
    benzonitrile 39.26
    trioctyl phosphate 25.37
    1-bromopropane 92.46
    gamma-valerolactone 190.1
    n-decanol 16.95
    triethyl phosphate 44.64
    4-methyl-2-pentanol 23.86
    propionitrile 20.61
    vinylene carbonate 65.59
    1,1,2-trichlorotrifluoroethane 70.77
    DMS 52.58
    cumene 33.26
    2-octanol 19.91
    2-hexanone 65.84
    octyl acetate 41.43
    limonene 45.85
    1,2-dimethoxyethane 62.2
    ethyl orthosilicate 50.26
    tributyl phosphate 29.81
    diacetone alcohol 53.85
    N,N-dimethylaniline 53.61
    acrylonitrile 16.84
    aniline 67.7
    1,3-propanediol 14.21
    bromobenzene 140.69
    dibromomethane 134.18
    1,1,2,2-tetrachloroethane 160.19
    2-methyl-cyclohexyl acetate 76.37
    tetrabutyl urea 42.35
    diisobutyl methanol 23.72
    2-phenylethanol 59.2
    styrene 56.23
    dioctyl adipate 54.1
    dimethyl sulfate 39.56
    ethyl butyrate 75.82
    methyl lactate 21.91
    butyl lactate 60.04
    diethyl carbonate 44.42
    propanediol butyl ether 32.81
    triethyl orthoformate 70.85
    p-tert-butyltoluene 29.96
    methyl 4-tert-butylbenzoate 87.29
    morpholine 101.55
    tert-butylamine 11.71
    n-dodecanol 10.97
    dimethoxymethane 51.38
    ethylene carbonate 65.03
    cyrene 67.34
    2-ethoxyethyl acetate 119.79
    2-ethylhexyl acetate 88.33
    1,2,4-trichlorobenzene 128.08
    4-methylpyridine 117.56
    dibutyl ether 36.86
    2,6-dimethyl-4-heptanol 23.72
    DEF 89.68
    dimethyl isosorbide 122.91
    tetrachloroethylene 108.29
    eugenol 70.7
    triacetin 90.07
    span 80 59.27
    1,4-butanediol 5.76
    1,1-dichloroethane 85.11
    2-methyl-1-pentanol 38.06
    methyl formate 11.11
    2-methyl-1-butanol 42.29
    n-decane 4.54
    butyronitrile 29.58
    3,7-dimethyl-1-octanol 26.37
    1-chlorooctane 22.44
    1-chlorotetradecane 6.8
    n-nonane 3.69
    undecane 2.67
    tert-butylcyclohexane 8.39
    cyclooctane 9.12
    cyclopentanol 38.44
    tetrahydropyran 146.57
    tert-amyl methyl ether 47.52
    2,5,8-trioxanonane 84.46
    1-hexene 33.31
    2-isopropoxyethanol 36.83
    2,2,2-trifluoroethanol 12.27
    methyl butyrate 70.05

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction