Cholesteryl myristate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    1989-52-2

    Molecular formula
    C41H72O2

    SMILES
    CCCCCCCCCCCCCC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CC[C@@H]4[C@H](C)CCCC(C)C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Waxy 62.87%
    Woody 59.37%
    Oily 41.13%
    Fatty 39.31%
    Balsamic 39.04%
    Sandalwood 38.49%
    Amber 32.04%
    Floral 30.48%
    Dry 24.98%
    Green 24.55%

     

    Flavor
    Waxy 34.38%
    Mild 29.59%
    Bland 24.75%
    Oily 24.18%
    Fatty 23.75%
    Woody 23.64%
    Faint 22.42%
    Slightly waxy 21.92%
    Delicate 21.04%
    Sandalwood 20.97%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    15.4

    pKa est.
    4.49 (weak acid)

    Molecular weight
    597.0 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    591°C

    Flash point

    • 221.3 ˚C est.

  • Synonyms

    • Cholesteryl myristate
    • 1989-52-2
    • Cholestryl myristate
    • Cholesteryl tetradecanoate
    • Cholesterol, myristate
    • CHEBI:84304
    • [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] tetradecanoate
    • ((3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((2R)-6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-3-yl) tetradecanoate
    • RefChem:576069
    • 217-867-8
    • Cholesterol Myristate
    • Cholest-5-en-3-ol (3beta)-, 3-tetradecanoate
    • CE(14:0)
    • Cholest-5-en-3beta-yl myristate
    • 1-myristoyl-cholesterol
    • 14:0 Cholesteryl ester
    • cholest-5-en-3beta-yl tetradecanoate
    • MFCD00014256
    • Cholesterol Ester(14:0)
    • Myristic Acid Cholesterol Ester
    • cholesterol 1-tetradecanoic acid
    • Cholesterol Ester(14:0/0:0)
    • CE(14:0/0:0)
    • C41H72O2
    • 5-Cholesten-3beta-ol Palmitate; Cholest-5-en-3beta-ol Palmitate; Cholesterol Tetradecanoate; Cholesteryl Tetradecanoate; NSC 226867;
    • EINECS 217-867-8
    • NSC 226867
    • Cholesteryl myristate;Cholesteryl tetradecanoate
    • Cholestryl myristic acid
    • cholesterol 1-myristoate
    • cholesteryl 1-myristoate
    • 14:0 Cholesterol ester
    • cholesterol 1-tetradecanoate
    • cholesteryl 1-tetradecanoate
    • cholesterol 1-myristoic acid
    • cholesteryl 1-myristoic acid
    • Cholesteryl tetradecanoic acid
    • SCHEMBL161746
    • orb1299274
    • cholesteryl 1-tetradecanoic acid
    • Cholest-5-en-3-yl myristate #
    • 5-Cholesten-3.beta.-ol myristate
    • HY-N2338
    • LMST01020004
    • MSK176864
    • AKOS025285999
    • CS-6327
    • FC61972
    • [(3S,8S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] tetradecanoate
    • AS-64976
    • BP-29630
    • cholest-5-en-3beta-yl tetradecanoic acid
    • SY059903
    • (3beta)-cholest-5-en-3-yl tetradecanoate
    • Cholest-5-en-3-ol (3beta)-tetradecanoate
    • C0675
    • NS00045437
    • Cholest-5-en-3-ol (3|A)-, 3-tetradecanoate
    • Cholest-5-en-3-ol (3beta)-tetradecanoic acid
    • D95276
    • 989C522
    • Q27157667
    • 1989-52-2

  • Applications

    Cholesteryl myristate (CAS 1989-52-2) is a waxy lipid commonly used in cosmetics and personal care as an emollient and structuring agent, helping soften the skin and improve the stability and satin finish of products such as creams, lotions, and lipsticks. It also serves as a fragrance carrier or fixative in perfumery, aiding fragrance release and texture. In pharmaceutical topical formulations it can function as a lipid-based excipient or carrier to support solubility and distribution of active ingredients. Additionally, as a wax-like additive, it may be used in coatings/inks and plastics formulations to modify gloss, slip, and texture and contribute to formulation stability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 21.87
    methanol 8.41
    isopropanol 17.09
    water 0.07
    ethyl acetate 77.08
    n-propanol 36.24
    acetone 41.5
    n-butanol 44.27
    acetonitrile 11.58
    DMF 43.96
    toluene 110.71
    isobutanol 30.6
    1,4-dioxane 92.49
    methyl acetate 42.26
    THF 190.38
    2-butanone 77.06
    n-pentanol 36.89
    sec-butanol 25.98
    n-hexane 11.32
    ethylene glycol 0.98
    NMP 154.68
    cyclohexane 23.26
    DMSO 23.72
    n-butyl acetate 93.08
    n-octanol 25.58
    chloroform 241.53
    n-propyl acetate 67.96
    acetic acid 27.05
    dichloromethane 197.43
    cyclohexanone 188.16
    propylene glycol 2.8
    isopropyl acetate 81.08
    DMAc 125.04
    2-ethoxyethanol 43.62
    isopentanol 42.35
    n-heptane 10.23
    ethyl formate 26.79
    1,2-dichloroethane 107.23
    n-hexanol 42.54
    2-methoxyethanol 34.42
    isobutyl acetate 62.59
    tetrachloromethane 51.63
    n-pentyl acetate 115.38
    transcutol 184.0
    n-heptanol 37.48
    ethylbenzene 54.02
    MIBK 74.15
    2-propoxyethanol 86.65
    tert-butanol 15.51
    MTBE 45.22
    2-butoxyethanol 84.12
    propionic acid 27.46
    o-xylene 64.61
    formic acid 6.02
    diethyl ether 72.18
    m-xylene 68.01
    p-xylene 56.45
    chlorobenzene 128.51
    dimethyl carbonate 29.72
    n-octane 3.33
    formamide 8.22
    cyclopentanone 165.93
    2-pentanone 88.65
    anisole 81.41
    cyclopentyl methyl ether 138.79
    gamma-butyrolactone 145.9
    1-methoxy-2-propanol 45.86
    pyridine 128.16
    3-pentanone 86.51
    furfural 101.07
    n-dodecane 1.95
    diethylene glycol 20.78
    diisopropyl ether 28.72
    tert-amyl alcohol 23.56
    acetylacetone 89.61
    n-hexadecane 2.41
    acetophenone 83.88
    methyl propionate 67.46
    isopentyl acetate 103.34
    trichloroethylene 213.51
    n-nonanol 30.71
    cyclohexanol 56.04
    benzyl alcohol 51.62
    2-ethylhexanol 40.95
    isooctanol 35.43
    dipropyl ether 65.98
    1,2-dichlorobenzene 118.92
    ethyl lactate 31.1
    propylene carbonate 87.73
    n-methylformamide 19.67
    2-pentanol 31.46
    n-pentane 11.27
    1-propoxy-2-propanol 74.97
    1-methoxy-2-propyl acetate 118.69
    2-(2-methoxypropoxy) propanol 70.71
    mesitylene 40.79
    ε-caprolactone 196.88
    p-cymene 37.79
    epichlorohydrin 162.52
    1,1,1-trichloroethane 118.32
    2-aminoethanol 5.65
    morpholine-4-carbaldehyde 118.74
    sulfolane 148.61
    2,2,4-trimethylpentane 7.31
    2-methyltetrahydrofuran 161.68
    n-hexyl acetate 103.84
    isooctane 4.68
    2-(2-butoxyethoxy)ethanol 85.89
    sec-butyl acetate 67.32
    tert-butyl acetate 85.93
    decalin 12.76
    glycerin 5.48
    diglyme 166.91
    acrylic acid 19.44
    isopropyl myristate 38.0
    n-butyric acid 73.93
    acetyl acetate 60.26
    di(2-ethylhexyl) phthalate 45.99
    ethyl propionate 71.12
    nitromethane 37.45
    1,2-diethoxyethane 88.3
    benzonitrile 47.84
    trioctyl phosphate 29.39
    1-bromopropane 96.5
    gamma-valerolactone 223.2
    n-decanol 18.93
    triethyl phosphate 49.78
    4-methyl-2-pentanol 26.14
    propionitrile 24.74
    vinylene carbonate 79.78
    1,1,2-trichlorotrifluoroethane 83.4
    DMS 62.89
    cumene 35.58
    2-octanol 22.84
    2-hexanone 73.65
    octyl acetate 47.37
    limonene 49.15
    1,2-dimethoxyethane 72.33
    ethyl orthosilicate 55.5
    tributyl phosphate 34.52
    diacetone alcohol 62.28
    N,N-dimethylaniline 57.54
    acrylonitrile 20.65
    aniline 73.81
    1,3-propanediol 16.98
    bromobenzene 155.15
    dibromomethane 145.14
    1,1,2,2-tetrachloroethane 179.44
    2-methyl-cyclohexyl acetate 85.49
    tetrabutyl urea 48.3
    diisobutyl methanol 25.95
    2-phenylethanol 64.81
    styrene 59.63
    dioctyl adipate 62.08
    dimethyl sulfate 49.49
    ethyl butyrate 85.99
    methyl lactate 25.99
    butyl lactate 72.15
    diethyl carbonate 51.34
    propanediol butyl ether 39.24
    triethyl orthoformate 79.68
    p-tert-butyltoluene 33.72
    methyl 4-tert-butylbenzoate 100.23
    morpholine 116.02
    tert-butylamine 13.96
    n-dodecanol 12.23
    dimethoxymethane 60.61
    ethylene carbonate 78.9
    cyrene 76.12
    2-ethoxyethyl acetate 144.44
    2-ethylhexyl acetate 99.27
    1,2,4-trichlorobenzene 144.5
    4-methylpyridine 129.95
    dibutyl ether 41.58
    2,6-dimethyl-4-heptanol 25.95
    DEF 99.98
    dimethyl isosorbide 140.68
    tetrachloroethylene 121.16
    eugenol 79.92
    triacetin 109.06
    span 80 67.23
    1,4-butanediol 7.05
    1,1-dichloroethane 97.02
    2-methyl-1-pentanol 40.38
    methyl formate 14.2
    2-methyl-1-butanol 46.19
    n-decane 4.94
    butyronitrile 34.41
    3,7-dimethyl-1-octanol 29.39
    1-chlorooctane 25.03
    1-chlorotetradecane 7.45
    n-nonane 4.08
    undecane 2.87
    tert-butylcyclohexane 8.95
    cyclooctane 9.69
    cyclopentanol 45.11
    tetrahydropyran 159.49
    tert-amyl methyl ether 51.63
    2,5,8-trioxanonane 97.74
    1-hexene 34.71
    2-isopropoxyethanol 42.45
    2,2,2-trifluoroethanol 16.13
    methyl butyrate 81.19

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction