Cholesteryl heptanoate

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  • Identifiers

    CAS number
    1182-07-6

    Molecular formula
    C34H58O2

    SMILES
    CCCCCCC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CC[C@@H]4[C@H](C)CCCC(C)C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 74.67%
    Waxy 46.45%
    Sandalwood 46.25%
    Balsamic 46.02%
    Amber 40.82%
    Floral 38.49%
    Oily 37.25%
    Herbal 33.44%
    Dry 33.37%
    Vetiver 30.43%

     

    Flavor
    Woody 34.65%
    Waxy 29.41%
    Mild 26.98%
    Herbal 25.02%
    Herb 23.83%
    Wood 23.21%
    Oily 22.31%
    Balsam 21.7%
    Sandalwood 21.53%
    Spice 21.31%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    11.6

    pKa est.
    7.41 (neutral)

    Molecular weight
    498.8 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    526°C

    Flash point

    • 238.28 ˚C est.

  • Synonyms

    • Cholesteryl heptanoate
    • 1182-07-6
    • Cholest-5-ene-3-beta-yl heptanoate
    • RefChem:1081479
    • 214-654-1
    • Cholesterol Heptanoate
    • Cholesterol Enanthate
    • Cholesteryl Heptanoate (Enanthate)
    • MFCD00003641
    • [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] heptanoate
    • Enanthic Acid Cholesterol Ester
    • Heptanoic Acid Cholesterol Ester
    • C34H58O2
    • Cholesteryl enanthate
    • cholesteryl heptylate
    • cholesterol n-heptanoate
    • EINECS 214-654-1
    • cholesteryl n-heptylate
    • Cholest-5-en-3-ol (3.beta.)-, heptanoate
    • Cholesteryl normal-heptylate
    • CHOLESTERYL HEPTONATE
    • SCHEMBL162885
    • cholest-5-en-3-yl heptanoate
    • orb2944015
    • DTXSID30922625
    • Cholest-5-en-3beta-yl heptanoate
    • 3.beta.-Heptanoyloxycholest-5-ene
    • AKOS024307556
    • FC61969
    • HY-W127348
    • (3I(2))-cholest-5-en-3-yl heptanoate
    • AS-57758
    • CHOLEST-5-EN-3-BETA-YL HEPTANOATE
    • CS-0185586
    • NS00046040
    • ST50330588
    • D95351
    • [(3S,8S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] heptanoate
    • 14-((1S)-1,5-dimethylhexyl)(1S,5S,10S,11S,2R,14R,15R)-2,15-dimethyltetracyclo[ 8.7.0.0<2,7>.0<11,15>]heptadec-7-en-5-yl heptanoate
    • 1182-07-6

  • Applications

    Cholesteryl heptanoate (CAS 1182-07-6) is a wax-like cholesterol ester primarily used in cosmetics and personal care as an emollient and texture-enhancing ingredient, helping slip and stabilizing the rheology of creams, lotions, and lip products. Its waxy character supports its role as a thickener and structuring agent in skincare formulations. In perfumery, it can function as a fragrance carrier and help with fragrance release and longevity due to its high molecular weight. In industrial formulations, it is used as a wax-like additive in polymers and coatings to adjust rheology, gloss, and texture. In household and surface-care products, it may be employed to improve feel and conditioning on treated surfaces. Each application is subject to formulation limits and regulatory compliance.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 27.36
    methanol 8.33
    isopropanol 22.35
    water 0.06
    ethyl acetate 75.98
    n-propanol 43.66
    acetone 40.74
    n-butanol 55.74
    acetonitrile 11.1
    DMF 41.1
    toluene 129.31
    isobutanol 36.38
    1,4-dioxane 102.21
    methyl acetate 39.34
    THF 191.25
    2-butanone 76.17
    n-pentanol 41.71
    sec-butanol 29.86
    n-hexane 9.48
    ethylene glycol 1.02
    NMP 129.88
    cyclohexane 22.08
    DMSO 20.14
    n-butyl acetate 84.98
    n-octanol 24.67
    chloroform 233.17
    n-propyl acetate 60.09
    acetic acid 24.92
    dichloromethane 181.13
    cyclohexanone 172.27
    propylene glycol 3.04
    isopropyl acetate 80.14
    DMAc 113.63
    2-ethoxyethanol 48.34
    isopentanol 52.88
    n-heptane 8.24
    ethyl formate 24.07
    1,2-dichloroethane 102.89
    n-hexanol 49.72
    2-methoxyethanol 41.17
    isobutyl acetate 58.29
    tetrachloromethane 44.01
    n-pentyl acetate 94.71
    transcutol 223.96
    n-heptanol 37.11
    ethylbenzene 52.03
    MIBK 75.57
    2-propoxyethanol 101.07
    tert-butanol 18.13
    MTBE 49.34
    2-butoxyethanol 82.37
    propionic acid 25.6
    o-xylene 65.97
    formic acid 5.56
    diethyl ether 82.89
    m-xylene 77.22
    p-xylene 54.31
    chlorobenzene 125.24
    dimethyl carbonate 26.24
    n-octane 2.39
    formamide 7.63
    cyclopentanone 147.89
    2-pentanone 89.71
    anisole 82.6
    cyclopentyl methyl ether 138.06
    gamma-butyrolactone 123.85
    1-methoxy-2-propanol 55.04
    pyridine 128.75
    3-pentanone 81.79
    furfural 91.11
    n-dodecane 1.49
    diethylene glycol 25.16
    diisopropyl ether 30.51
    tert-amyl alcohol 24.55
    acetylacetone 85.96
    n-hexadecane 1.86
    acetophenone 78.46
    methyl propionate 63.52
    isopentyl acetate 98.76
    trichloroethylene 202.73
    n-nonanol 29.09
    cyclohexanol 62.73
    benzyl alcohol 54.57
    2-ethylhexanol 42.38
    isooctanol 34.13
    dipropyl ether 61.08
    1,2-dichlorobenzene 111.59
    ethyl lactate 28.68
    propylene carbonate 75.35
    n-methylformamide 17.34
    2-pentanol 37.38
    n-pentane 10.77
    1-propoxy-2-propanol 81.6
    1-methoxy-2-propyl acetate 118.45
    2-(2-methoxypropoxy) propanol 70.54
    mesitylene 43.24
    ε-caprolactone 174.93
    p-cymene 35.15
    epichlorohydrin 153.8
    1,1,1-trichloroethane 104.2
    2-aminoethanol 6.32
    morpholine-4-carbaldehyde 115.37
    sulfolane 120.89
    2,2,4-trimethylpentane 6.68
    2-methyltetrahydrofuran 157.07
    n-hexyl acetate 88.96
    isooctane 4.68
    2-(2-butoxyethoxy)ethanol 94.22
    sec-butyl acetate 61.52
    tert-butyl acetate 81.83
    decalin 11.18
    glycerin 6.14
    diglyme 174.72
    acrylic acid 17.6
    isopropyl myristate 33.65
    n-butyric acid 71.6
    acetyl acetate 57.15
    di(2-ethylhexyl) phthalate 42.8
    ethyl propionate 60.63
    nitromethane 32.44
    1,2-diethoxyethane 92.95
    benzonitrile 49.88
    trioctyl phosphate 26.87
    1-bromopropane 95.31
    gamma-valerolactone 213.19
    n-decanol 18.04
    triethyl phosphate 42.23
    4-methyl-2-pentanol 30.51
    propionitrile 24.05
    vinylene carbonate 69.3
    1,1,2-trichlorotrifluoroethane 77.37
    DMS 55.42
    cumene 33.96
    2-octanol 21.16
    2-hexanone 67.51
    octyl acetate 41.59
    limonene 46.14
    1,2-dimethoxyethane 76.67
    ethyl orthosilicate 48.96
    tributyl phosphate 30.95
    diacetone alcohol 62.5
    N,N-dimethylaniline 56.64
    acrylonitrile 20.19
    aniline 81.7
    1,3-propanediol 20.21
    bromobenzene 147.81
    dibromomethane 136.24
    1,1,2,2-tetrachloroethane 163.66
    2-methyl-cyclohexyl acetate 76.93
    tetrabutyl urea 42.93
    diisobutyl methanol 24.98
    2-phenylethanol 70.82
    styrene 58.67
    dioctyl adipate 55.03
    dimethyl sulfate 39.95
    ethyl butyrate 75.03
    methyl lactate 24.9
    butyl lactate 62.8
    diethyl carbonate 44.85
    propanediol butyl ether 40.08
    triethyl orthoformate 70.72
    p-tert-butyltoluene 31.06
    methyl 4-tert-butylbenzoate 90.91
    morpholine 129.8
    tert-butylamine 15.72
    n-dodecanol 11.69
    dimethoxymethane 64.11
    ethylene carbonate 69.78
    cyrene 73.84
    2-ethoxyethyl acetate 127.58
    2-ethylhexyl acetate 90.34
    1,2,4-trichlorobenzene 134.71
    4-methylpyridine 134.68
    dibutyl ether 36.45
    2,6-dimethyl-4-heptanol 24.98
    DEF 94.37
    dimethyl isosorbide 134.46
    tetrachloroethylene 111.54
    eugenol 77.01
    triacetin 91.63
    span 80 65.58
    1,4-butanediol 8.09
    1,1-dichloroethane 93.3
    2-methyl-1-pentanol 44.8
    methyl formate 11.88
    2-methyl-1-butanol 54.27
    n-decane 3.72
    butyronitrile 36.79
    3,7-dimethyl-1-octanol 28.79
    1-chlorooctane 20.7
    1-chlorotetradecane 6.23
    n-nonane 3.02
    undecane 2.19
    tert-butylcyclohexane 7.7
    cyclooctane 8.55
    cyclopentanol 44.71
    tetrahydropyran 173.23
    tert-amyl methyl ether 51.0
    2,5,8-trioxanonane 100.17
    1-hexene 31.46
    2-isopropoxyethanol 46.54
    2,2,2-trifluoroethanol 13.92
    methyl butyrate 69.69

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction