Chlorotrifluoromethane

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  • Identifiers

    CAS number
    75-72-9

    Molecular formula
    CClF3

    SMILES
    C(F)(F)(F)Cl

    Safety labels

    Compressed Gas
    Compressed Gas

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 46.14%
    Sweet 25.7%
    Fishy 24.34%
    Floral 20.97%
    Balsamic 18.82%
    Woody 18.12%
    Animal 17.72%
    Fresh 17.58%
    Ripe 17.0%
    Earthy 16.72%

     

    Flavor
    Odorless 36.53%
    Sulfurous 24.46%
    Sulfury 22.86%
    Meaty 21.08%
    Fishy 18.83%
    Bloody 18.5%
    Glue 18.48%
    Rotten 18.37%
    Bouillon 18.1%
    Mousy 18.06%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.0

    pKa est.
    4.43 (weak acid)

    Molecular weight
    104.46 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -294 °F (USCG, 1999)
    • -181 °C

    Boiling point

    • -114 °F at 760 mmHg (USCG, 1999)
    • -81.4 °C @ 760 MM HG
    • -81.4 °C

    Flash point

    • -9.57 ˚C est.

    Solubility expt.

    • Water solubility = 60.1 mg/l @ 25 °C
    • Solubility in water: none

  • Synonyms

    • CHLOROTRIFLUOROMETHANE
    • Trifluoromethyl chloride
    • 75-72-9
    • Trifluorochloromethane
    • Monochlorotrifluoromethane
    • Methane, chlorotrifluoro-
    • Genetron 13
    • Arcton 3
    • chloro(trifluoro)methane
    • Frigen 13
    • CFC-13
    • Freon 13
    • Fluorocarbon 13
    • Trifluoromonochlorocarbon
    • Halocarbon 13/ucon 13
    • Methane, monochlorotrifluoro-
    • Khladon 13
    • FC 13
    • CF3Cl
    • HSDB 140
    • Refrigerant 13
    • EINECS 200-894-4
    • 7C6U91JNED
    • UN1022
    • BRN 1732392
    • F 13
    • R 13
    • REFRIGERANT-13
    • FREON-13
    • DTXSID4052500
    • 4-01-00-00034 (Beilstein Handbook Reference)
    • TRIFLUOROMONOCHLOROCARBON [HSDB]
    • CClF3
    • UNII-7C6U91JNED
    • Halocarbon 13
    • Chlorotrifluromethane
    • MFCD00000773
    • Methane, chlorotrifluoro
    • Trifluoro-chloro-methane
    • REFRIGERANT R 13
    • Methane, monochlorotrifluoro
    • FREON R 13
    • SCHEMBL27896
    • R 13 (REFRIGERANT)
    • REFRIGERANT GAS R-13
    • CFC 13
    • Chlorotrifluoromethane, >=99%
    • FKW 13
    • SCHEMBL3495970
    • DTXCID8031073
    • AFYPFACVUDMOHA-UHFFFAOYSA-
    • AKOS015853107
    • InChI=1/CClF3/c2-1(3,4)5
    • UN 1022
    • R-13
    • NS00041084
    • Chlorotrifluoromethane or Refrigerant gas R 13
    • Q423046
    • Chlorotrifluoromethane or Refrigerant gas R 13 [UN1022] [Nonflammable gas]
    • 200-894-4

  • Applications

    Chlorotrifluoromethane (CAS 75-72-9) has historically been used as a refrigerant in cooling equipment and as a blowing agent for polyurethane foam and polystyrene foam; it is also employed as a solvent or specialty cleaning fluid for precision parts and electronics, and serves as an intermediate in the synthesis of fluorinated chemicals; it may function as a processing solvent or additive in coatings and inks. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 386.77
    methanol 679.04
    isopropanol 325.92
    water 274.16
    ethyl acetate 109.11
    n-propanol 251.11
    acetone 379.51
    n-butanol 188.03
    acetonitrile 225.62
    DMF 1196.53
    toluene 46.18
    isobutanol 172.48
    1,4-dioxane 240.44
    methyl acetate 138.3
    THF 389.78
    2-butanone 176.43
    n-pentanol 127.4
    sec-butanol 207.84
    n-hexane 41.46
    ethylene glycol 280.83
    NMP 609.51
    cyclohexane 49.48
    DMSO 1417.46
    n-butyl acetate 63.14
    n-octanol 80.6
    chloroform 106.26
    n-propyl acetate 80.55
    acetic acid 252.37
    dichloromethane 150.56
    cyclohexanone 149.21
    propylene glycol 170.71
    isopropyl acetate 80.17
    DMAc 738.1
    2-ethoxyethanol 283.34
    isopentanol 142.29
    n-heptane 41.31
    ethyl formate 124.74
    1,2-dichloroethane 140.56
    n-hexanol 90.16
    2-methoxyethanol 493.39
    isobutyl acetate 40.2
    tetrachloromethane 34.33
    n-pentyl acetate 62.77
    transcutol 261.59
    n-heptanol 70.77
    ethylbenzene 31.36
    MIBK 95.42
    2-propoxyethanol 208.55
    tert-butanol 341.32
    MTBE 182.71
    2-butoxyethanol 132.78
    propionic acid 144.41
    o-xylene 54.93
    formic acid 316.76
    diethyl ether 215.4
    m-xylene 43.88
    p-xylene 36.45
    chlorobenzene 32.15
    dimethyl carbonate 118.85
    n-octane 20.77
    formamide 506.55
    cyclopentanone 221.37
    2-pentanone 152.68
    anisole 83.02
    cyclopentyl methyl ether 167.2
    gamma-butyrolactone 228.43
    1-methoxy-2-propanol 356.7
    pyridine 152.23
    3-pentanone 132.71
    furfural 199.4
    n-dodecane 14.55
    diethylene glycol 228.86
    diisopropyl ether 69.67
    tert-amyl alcohol 215.46
    acetylacetone 145.5
    n-hexadecane 15.09
    acetophenone 81.6
    methyl propionate 139.85
    isopentyl acetate 49.71
    trichloroethylene 116.72
    n-nonanol 72.33
    cyclohexanol 138.5
    benzyl alcohol 83.11
    2-ethylhexanol 55.06
    isooctanol 56.45
    dipropyl ether 115.4
    1,2-dichlorobenzene 32.79
    ethyl lactate 79.15
    propylene carbonate 94.02
    n-methylformamide 493.78
    2-pentanol 145.93
    n-pentane 76.26
    1-propoxy-2-propanol 150.9
    1-methoxy-2-propyl acetate 85.89
    2-(2-methoxypropoxy) propanol 115.68
    mesitylene 37.76
    ε-caprolactone 118.95
    p-cymene 33.79
    epichlorohydrin 188.38
    1,1,1-trichloroethane 64.69
    2-aminoethanol 312.47
    morpholine-4-carbaldehyde 424.09
    sulfolane 369.25
    2,2,4-trimethylpentane 25.23
    2-methyltetrahydrofuran 193.09
    n-hexyl acetate 72.57
    isooctane 19.52
    2-(2-butoxyethoxy)ethanol 141.17
    sec-butyl acetate 50.08
    tert-butyl acetate 84.68
    decalin 16.17
    glycerin 242.82
    diglyme 274.63
    acrylic acid 151.14
    isopropyl myristate 44.27
    n-butyric acid 125.28
    acetyl acetate 64.14
    di(2-ethylhexyl) phthalate 41.34
    ethyl propionate 81.97
    nitromethane 393.07
    1,2-diethoxyethane 110.44
    benzonitrile 59.41
    trioctyl phosphate 39.18
    1-bromopropane 102.35
    gamma-valerolactone 242.59
    n-decanol 58.59
    triethyl phosphate 45.36
    4-methyl-2-pentanol 86.55
    propionitrile 144.33
    vinylene carbonate 87.62
    1,1,2-trichlorotrifluoroethane 171.98
    DMS 66.2
    cumene 29.14
    2-octanol 59.43
    2-hexanone 94.91
    octyl acetate 55.08
    limonene 50.55
    1,2-dimethoxyethane 405.06
    ethyl orthosilicate 46.36
    tributyl phosphate 39.2
    diacetone alcohol 134.63
    N,N-dimethylaniline 108.57
    acrylonitrile 173.99
    aniline 88.92
    1,3-propanediol 246.37
    bromobenzene 25.57
    dibromomethane 117.55
    1,1,2,2-tetrachloroethane 123.53
    2-methyl-cyclohexyl acetate 49.28
    tetrabutyl urea 76.97
    diisobutyl methanol 52.07
    2-phenylethanol 60.17
    styrene 35.8
    dioctyl adipate 56.94
    dimethyl sulfate 196.65
    ethyl butyrate 67.04
    methyl lactate 141.82
    butyl lactate 67.22
    diethyl carbonate 46.14
    propanediol butyl ether 123.96
    triethyl orthoformate 57.71
    p-tert-butyltoluene 36.62
    methyl 4-tert-butylbenzoate 100.98
    morpholine 309.66
    tert-butylamine 251.86
    n-dodecanol 50.15
    dimethoxymethane 516.07
    ethylene carbonate 78.14
    cyrene 116.88
    2-ethoxyethyl acetate 71.47
    2-ethylhexyl acetate 41.41
    1,2,4-trichlorobenzene 38.39
    4-methylpyridine 130.41
    dibutyl ether 68.78
    2,6-dimethyl-4-heptanol 52.07
    DEF 278.34
    dimethyl isosorbide 147.45
    tetrachloroethylene 97.81
    eugenol 99.02
    triacetin 76.38
    span 80 97.11
    1,4-butanediol 133.55
    1,1-dichloroethane 104.84
    2-methyl-1-pentanol 86.78
    methyl formate 308.98
    2-methyl-1-butanol 138.37
    n-decane 22.0
    butyronitrile 118.76
    3,7-dimethyl-1-octanol 64.68
    1-chlorooctane 43.16
    1-chlorotetradecane 23.4
    n-nonane 22.75
    undecane 17.14
    tert-butylcyclohexane 15.75
    cyclooctane 22.87
    cyclopentanol 180.08
    tetrahydropyran 180.85
    tert-amyl methyl ether 151.58
    2,5,8-trioxanonane 209.8
    1-hexene 73.47
    2-isopropoxyethanol 168.7
    2,2,2-trifluoroethanol 144.57
    methyl butyrate 105.17

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction