Chlorine Dioxide

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  • Identifiers

    CAS number
    10049-04-4

    Molecular formula
    ClO2

    SMILES
    O=Cl[O]

    Safety labels

    Oxidizer
    Oxidizer

    Compressed Gas
    Compressed Gas

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 59.69%
    Alcoholic 24.98%
    Fishy 23.3%
    Sweet 21.11%
    Ethereal 20.83%
    Fresh 16.21%
    Fruity 16.03%
    Cheesy 15.77%
    Sulfurous 15.25%
    Solvent 15.07%

     

    Flavor
    Odorless 47.59%
    Sulfurous 28.57%
    Fishy 25.53%
    Sulfury 25.09%
    Pungent 21.28%
    Rotten 20.32%
    Very slight 20.14%
    Mousy 20.04%
    Meaty 19.91%
    Formyl 19.89%

     

    Odor impact est.
    High

    Odor threshold

    • Odor Threshold Low: 0.1 [ppm]. Odor Threshold High: 15.0 [ppm]. [ACGIH] Odor threshold from NJ "Hazardous Substance Fact Sheet"

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    1.13 (strong acid)

    Molecular weight
    67.45 g/mol

    Melting point expt.

    • -74 °F (NIOSH, 2024)
    • -59 °C
    • -74 °F

    Boiling point

    • 52 °F at 760 mmHg (NIOSH, 2024)
    • 11 °C
    • 52 °F

    Flash point

    • 53.2 ˚C est.
    • NA (Gas) ? (Liquid)

    Solubility expt.

    • 0.3 % at 77 °F (NIOSH, 2024)
    • In water, 3.01 g/L at 25 °C and 34.5 mm Hg
    • 2000 cc (gas) in 100 cc cold water
    • In water, 1.823X10-2 at 298.15 K
    • Soluble in water
    • Soluble in alkaline and sulfuric acid solutions
    • Solubility in water, g/100ml at 20 °C: 0.8
    • (77 °F): 0.3%

  • Synonyms

    • CHLORINE DIOXIDE
    • Alcide
    • 10049-04-4
    • Chlorine oxide (ClO2)
    • Chlorine(IV) oxide
    • DTXSID5023958
    • Purite
    • Joyden
    • Joyden plus
    • Nobda disinfectant
    • BlueMAX Pre-Post
    • Gladiator Super Dry
    • BlueMAX Premium EU
    • RefChem:5668
    • SKIN N CLEAN
    • VIRUS ZERO-F
    • ProVtect Hand Sanitizer
    • Chlorine Dioxide(ClO2)
    • SANI-HEALTH Sanitizer
    • PURE O2 S
    • VIRUS KILL SANITIZER
    • PURE O2-S F
    • Chlorine dioxide disinfectant
    • M.C. (Morningcalm) V Zero
    • DMINE PENTOSE MEDI PLUS
    • 8061YMS4RM
    • DTXCID803958
    • Jiajia Gaseous Air Disinfectant
    • chlorine dioxide air disinfectant
    • CHEBI:37750
    • CHEBI:52357
    • KO-C100
    • SFP INC. NVO-2 TOPICAL NAVEL DIP
    • TBOSEN EMERGENCY STERILIZATION CARD
    • SFP INC. VO-2 SANITIZING TEAT DIP
    • Chlorine Dioxide Sustained Release Granules
    • 233-162-8
    • Anthium dioxcide
    • Chlorine Oxide
    • Chloroperoxyl
    • Chloryl radical
    • ClO2
    • Doxcide 50
    • Chlorine oxide?
    • dioxidochlorine(.)
    • Dioxo-lambda~5~-chloranyl
    • dioxido-lambda(5)-chloranyl
    • (OClO)(.)
    • O2Cl(.)
    • CHEBI:29415
    • [ClO2](.)
    • DB12453
    • E926
    • 10049-04-4

  • Applications

    Chlorine Dioxide (CAS 10049-04-4) functions as a powerful oxidizing disinfectant across several industrial sectors: in water treatment for disinfection and taste/odor control; in pulp and paper bleaching; in textile bleaching and fabric preparation; in sanitation of food processing equipment and surfaces; in cleaning and disinfection of facilities and equipment in pharmaceutical and healthcare environments; and in odor control and sanitization of wastewater and air streams.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 342.06
    methanol 479.25
    isopropanol 327.46
    water 75.1
    ethyl acetate 129.78
    n-propanol 238.46
    acetone 453.95
    n-butanol 220.35
    acetonitrile 258.93
    DMF 1455.8
    toluene 50.36
    isobutanol 178.34
    1,4-dioxane 323.31
    methyl acetate 177.19
    THF 528.73
    2-butanone 212.32
    n-pentanol 144.42
    sec-butanol 218.58
    n-hexane 30.43
    ethylene glycol 236.35
    NMP 612.44
    cyclohexane 36.86
    DMSO 1304.3
    n-butyl acetate 72.74
    n-octanol 94.5
    chloroform 114.6
    n-propyl acetate 87.81
    acetic acid 274.51
    dichloromethane 151.06
    cyclohexanone 178.44
    propylene glycol 165.58
    isopropyl acetate 94.94
    DMAc 717.29
    2-ethoxyethanol 268.54
    isopentanol 175.2
    n-heptane 26.32
    ethyl formate 136.05
    1,2-dichloroethane 152.82
    n-hexanol 105.52
    2-methoxyethanol 542.68
    isobutyl acetate 51.57
    tetrachloromethane 39.49
    n-pentyl acetate 74.26
    transcutol 365.77
    n-heptanol 78.72
    ethylbenzene 34.07
    MIBK 117.56
    2-propoxyethanol 223.99
    tert-butanol 455.78
    MTBE 247.52
    2-butoxyethanol 152.92
    propionic acid 151.97
    o-xylene 55.57
    formic acid 255.11
    diethyl ether 224.96
    m-xylene 49.31
    p-xylene 44.57
    chlorobenzene 55.94
    dimethyl carbonate 136.75
    n-octane 15.89
    formamide 361.61
    cyclopentanone 286.24
    2-pentanone 187.68
    anisole 106.03
    cyclopentyl methyl ether 189.38
    gamma-butyrolactone 273.67
    1-methoxy-2-propanol 401.17
    pyridine 171.67
    3-pentanone 138.56
    furfural 255.59
    n-dodecane 15.54
    diethylene glycol 244.97
    diisopropyl ether 77.55
    tert-amyl alcohol 275.27
    acetylacetone 191.81
    n-hexadecane 16.43
    acetophenone 93.45
    methyl propionate 158.01
    isopentyl acetate 64.14
    trichloroethylene 166.84
    n-nonanol 85.14
    cyclohexanol 151.66
    benzyl alcohol 93.35
    2-ethylhexanol 61.16
    isooctanol 63.22
    dipropyl ether 96.37
    1,2-dichlorobenzene 56.57
    ethyl lactate 78.53
    propylene carbonate 119.17
    n-methylformamide 454.53
    2-pentanol 169.42
    n-pentane 50.01
    1-propoxy-2-propanol 159.92
    1-methoxy-2-propyl acetate 99.69
    2-(2-methoxypropoxy) propanol 145.88
    mesitylene 41.16
    ε-caprolactone 133.14
    p-cymene 32.35
    epichlorohydrin 267.08
    1,1,1-trichloroethane 104.7
    2-aminoethanol 254.82
    morpholine-4-carbaldehyde 489.63
    sulfolane 420.27
    2,2,4-trimethylpentane 23.34
    2-methyltetrahydrofuran 266.5
    n-hexyl acetate 92.24
    isooctane 20.63
    2-(2-butoxyethoxy)ethanol 195.37
    sec-butyl acetate 56.46
    tert-butyl acetate 120.77
    decalin 16.94
    glycerin 256.34
    diglyme 316.92
    acrylic acid 166.2
    isopropyl myristate 53.28
    n-butyric acid 147.33
    acetyl acetate 80.68
    di(2-ethylhexyl) phthalate 53.64
    ethyl propionate 88.14
    nitromethane 443.09
    1,2-diethoxyethane 137.36
    benzonitrile 83.39
    trioctyl phosphate 45.49
    1-bromopropane 99.83
    gamma-valerolactone 314.47
    n-decanol 69.75
    triethyl phosphate 47.96
    4-methyl-2-pentanol 97.52
    propionitrile 156.62
    vinylene carbonate 110.45
    1,1,2-trichlorotrifluoroethane 219.67
    DMS 81.5
    cumene 31.42
    2-octanol 69.01
    2-hexanone 107.61
    octyl acetate 67.42
    limonene 51.05
    1,2-dimethoxyethane 453.08
    ethyl orthosilicate 47.72
    tributyl phosphate 47.73
    diacetone alcohol 188.86
    N,N-dimethylaniline 111.51
    acrylonitrile 193.37
    aniline 97.83
    1,3-propanediol 275.81
    bromobenzene 45.53
    dibromomethane 110.52
    1,1,2,2-tetrachloroethane 154.8
    2-methyl-cyclohexyl acetate 54.3
    tetrabutyl urea 84.2
    diisobutyl methanol 57.13
    2-phenylethanol 75.68
    styrene 43.12
    dioctyl adipate 71.77
    dimethyl sulfate 245.79
    ethyl butyrate 66.08
    methyl lactate 147.08
    butyl lactate 74.9
    diethyl carbonate 49.09
    propanediol butyl ether 145.85
    triethyl orthoformate 58.91
    p-tert-butyltoluene 36.61
    methyl 4-tert-butylbenzoate 113.48
    morpholine 386.67
    tert-butylamine 275.74
    n-dodecanol 58.5
    dimethoxymethane 561.36
    ethylene carbonate 94.69
    cyrene 123.56
    2-ethoxyethyl acetate 93.25
    2-ethylhexyl acetate 50.83
    1,2,4-trichlorobenzene 67.8
    4-methylpyridine 163.61
    dibutyl ether 83.99
    2,6-dimethyl-4-heptanol 57.13
    DEF 301.38
    dimethyl isosorbide 183.83
    tetrachloroethylene 119.16
    eugenol 123.64
    triacetin 92.55
    span 80 121.92
    1,4-butanediol 133.96
    1,1-dichloroethane 124.73
    2-methyl-1-pentanol 108.78
    methyl formate 324.92
    2-methyl-1-butanol 155.02
    n-decane 21.07
    butyronitrile 142.55
    3,7-dimethyl-1-octanol 74.44
    1-chlorooctane 47.88
    1-chlorotetradecane 28.52
    n-nonane 20.32
    undecane 17.62
    tert-butylcyclohexane 17.62
    cyclooctane 15.91
    cyclopentanol 198.18
    tetrahydropyran 220.71
    tert-amyl methyl ether 185.55
    2,5,8-trioxanonane 261.53
    1-hexene 66.95
    2-isopropoxyethanol 178.65
    2,2,2-trifluoroethanol 147.91
    methyl butyrate 113.38

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction