Chlordecone

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  • Identifiers

    CAS number
    143-50-0

    Molecular formula
    C10Cl10O

    SMILES
    C1(=O)C2(C3(C4(C1(C5(C2(C3(C(C45Cl)(Cl)Cl)Cl)Cl)Cl)Cl)Cl)Cl)Cl

    Safety labels

    Acute Toxic
    Acute Toxic

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 53.44%
    Woody 39.95%
    Dry 20.44%
    Amber 19.08%
    Balsamic 16.11%
    Sweet 15.67%
    Earthy 15.56%
    Camphoreous 15.15%
    Clean 14.96%
    Cedar 13.8%

     

    Flavor
    Bitter 67.02%
    Odorless 27.84%
    Sweet-like 19.41%
    Bland 18.42%
    Nitrile 17.49%
    Cedarleaf 17.22%
    Rotten 17.13%
    Oriental 16.98%
    Scallion 16.64%
    Very strong 16.6%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.9

    pKa est.
    5.32 (weak acid)

    Molecular weight
    490.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 662 °F (decomposes) (NTP, 1992)
    • 350 °C (decomp)
    • 662 °F (Sublimes)

    Boiling point

    • Sublimes with decomposition at 662.0 °F (USCG, 1999)
    • Sublimes

    Flash point

    • 63.24 ˚C est.
    • >100.00 °C (>212.00 °F)

    Solubility expt.

    • less than 1 mg/mL at 73 °F (NTP, 1992)
    • Solubility in water: 4000 mg/L at 100 °C
    • 0.470 lb/100 lb water at 212 °F
    • In water, 2.70 mg/L at 25 °C
    • Soluble in strongly alkaline aqueous solution; readily soluble in acetone, less soluble in benzene & light petroleum
    • Slightly soluble in hydrocarbon solvents. Soluble in alcohols, ketones, acetic acid.
    • For more Solubility (Complete) data for Kepone (6 total), please visit the HSDB record page.
    • Solubility in water at 20 °C: poor
    • (212 °F): 0.5%

  • Synonyms

    • chlordecone
    • Kepone
    • 143-50-0
    • Clordecone
    • Merex
    • Decachloroketone
    • Chlordecone [ISO]
    • Chlordecone (kepone)
    • Compound 1189
    • Caswell No. 275
    • General chemicals 1189
    • Rcra waste number U142
    • Decachlorotetracyclodecanone
    • Kepone-2-one, decachlorooctahydro-
    • CCRIS 128
    • GC 1189
    • CHEBI:16548
    • HSDB 1558
    • UNII-RG5XJ88UDF
    • NCI-C00191
    • EINECS 205-601-3
    • Ciba 8514
    • ENT 16,391
    • EPA Pesticide Chemical Code 027701
    • NSC 124074
    • DTXSID1020770
    • AI3-16391
    • CHLORDECONE [MI]
    • RG5XJ88UDF
    • CHLORDECONE [HSDB]
    • CHLORDECONE [IARC]
    • Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta(cd)pentalen-2-one
    • Chlorodecone
    • DTXCID10770
    • Decachloro-1,3,4-metheno-2H-cyclobuta(cd)pentalen-2-one
    • Decachlorooctahydro-1,3,4-methano-2H-cyclobuta(cd)pentalen-2-one
    • Perchloropentacyclo(5.3.0.0(2,6).0(3,9).0(4,8))decan-5-one
    • Decachloropentacyclo(5.2.1.0(2,6).0(3,9).0(5),(8))decan-4-one
    • NSC-56532
    • 1,1a,3,3a,4,5,5,5a,5b,6-Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta(cd)pentalen-2-one
    • 1,1a,3,3a,4,5,5,5a,5b,6-decachlorooctahydro-2H-1,3,4-(methanetriyl)cyclobuta[cd]pentalen-2-one
    • 1,2,3,4,5,5,6,7,8,9,10,10-Dodecachlorooctahydro-1,3,4-metheno-2-cyclobuta(c,d)pentalone
    • 1,3,4-Metheno-2H-cyclobuta(cd)pentalen-2-one, 1,1a,3,3a,4,5,5,5a,5b,6-decachlorooctahydro-
    • 2,3,3a,4,5,6,7,7a,8,8a-Decachloro-3a,4,7,7a-tetrahydro-4,7-methanoinden-1-one
    • NSC-124074
    • Decachloropentacyclo[5.2.1.0(2,6).0(3,9).0(5,8)]decan-4-one
    • CHLORDECONE (IARC)
    • 1,3,4-Metheno-2H-cyclobuta[cd]pentalen-2-one, 1,1a,3,3a,4,5,5,5a,5b,6-decachlorooctahydro-
    • Decachlorotetrahydro-4,7-methanoindeneone
    • Perchloropentacyclo[5.3.0.02,6.03,9.04,8]decan-5-one
    • Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta[cd]pentalin-2-one
    • Decachloropentacyclo(5.3.0.0(2,6).0(4,10).0(5,9))decan-3-one
    • decachlorpentacyclo (5.2.1.0(2,6).0(3,9).0(5,8)) decan-4-one
    • perchloropentacyclo[5.3.0.0(2,6).0(3,9).0(4,8)]decan-5-one
    • ENT-16391
    • 1,2,3,4,6,7,8,9,10,10-decachloropentacyclo[5.3.0.0(2,6).0(3,9).0(4,8)]decan-5-one
    • 1,2,3,4,6,7,8,9,10,10-decachloropentacyclo[5.3.0.02,6.03,9.04,8]decan-5-one
    • 1,2,3,5,6,7,8,9,10,10-Decachloro(5.2.1.0(2,6).0(3,9) .0(5,8))decan-4-one
    • 1,3,4-Metheno-2H-cyclobuta(cd)pentalen-2-one, 1,1a,3,3a,4,5,5,5a,5b,6-decachloroctahydro-
    • CAS-143-50-0
    • SMR001261798
    • RCRA waste no. U142
    • chlordecane
    • hlordecane
    • decachloropentacyclo(5.3.0.02,6.03,9.04,8)decan-5-one
    • decachloropentacyclo[5.3.0.02,6.03,9.04,8]decan-5-one
    • Perchloropentacyclo(5.3.0.02,6.03,9.04,8)decan-5-one
    • NSC56532
    • 1,3,4-Metheno-2H-cyclobuta[cd]pentalen-2-one, decachlorooctahydro-
    • Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta(cd)pentalin-2-one
    • Decachloropentacyclo(5.2.1.0(2,6).0(3,9).0(5,8))decan-4-one
    • DECACHLOROPENTACYCLO(5.2.1.02,6.03,9.05,8)DECAN-4-ONE
    • DECACHLOROPENTACYCLO[5.2.1.02,6.03,9.05,8]DECAN-4-ONE
    • NSC124074
    • 1,3,4-METHENO-2H-CYCLOBUTA(CD)PENTALEN-2-ONE, DECACHLOROOCTAHYDRO-
    • Perchloropentacyclo
    • 1,1a,3,3a,4,5,5,5a,5b,6-decachlorooctahydro-2H-1,3,4-(methanetriyl)cyclobuta(cd)pentalen-2-one
    • 1,2,3,4,6,7,8,9,10,10-decachloropentacyclo(5.3.0.0(2,6).0(3,9).0(4,8))decan-5-one
    • GC-1189
    • Decachloropentacyclo(5.2.1.0(sup 2,6).0(sup 3,9).0(sup 5,8))decan-4-one
    • Decachloropentacyclo(5.3.0.0(sup 2,6).0(sup 4,10).0(sup 5,9))decan-3-one
    • Decachlorotetracyclo-decanone
    • 1,2,3,5,6,7,8,9,10,10-Decachloro(5.2.1.0(sup 2,6).0(sup 3,9).0(sup 5,8))decano-4-one
    • MLS002177806
    • MLS002454392
    • SCHEMBL119101
    • Kepone2one, decachlorooctahydro
    • Mirex 2385-85-5
    • CHEMBL462576
    • S00336a
    • Tox21_201592
    • Tox21_300098
    • BDBM50474727
    • AKOS015950798
    • Decachlorotetrahydro4,7methanoindeneone
    • USEPA/OPP Pesticide Code: 027701
    • NCGC00091008-01
    • NCGC00091008-02
    • NCGC00091008-03
    • NCGC00091008-04
    • NCGC00091008-05
    • NCGC00091008-06
    • NCGC00091008-07
    • NCGC00091008-08
    • NCGC00091008-09
    • NCGC00254136-01
    • NCGC00259141-01
    • Decachlorotetrahydro-4,7-methan-oindeneone
    • DB-042689
    • NS00021657
    • C01792
    • Chlordecone, PESTANAL(R), analytical standard
    • Decachloro1,3,4metheno2Hcyclobuta(cd)pentalen2one
    • Q423892
    • Chlordecone, 99%, vial of 1 g, (Kepone equiv.)
    • Decachlorooctahydro1,3,4methano2Hcyclobuta(cd)pentalen2one
    • Decachlorooctahydro1,3,4metheno2Hcyclobuta(cd)pentalen2one
    • Decachloropentacyclo(5.3.0.02,6.04,10.05,9)decan-3-one
    • Decachloropentacyclo(5.2.1.0(2,6).0(3,9).0(5),(8))decan4one
    • Perchloropentacyclo(5.3.0.0(2,6).0(3,9).0(4,8))decan5one
    • 2,3,3a,4,5,6,7,7a,8,8aDecachloro3a,4,7,7atetrahydro4,7methanoinden1one
    • Decachloropentacyclo(5.2.1.0(2,6).0(3,9).0(5,8))-decan-4-one
    • Decachloropentacyclo(5.2.1.0(sup 2,6).0(sup 3,9).0(sup 5,8))decan4one
    • Decachloropentacyclo(5.3.0.0(2,6).-0(4,10).0(5,9))-decan-3-one
    • 1,1a,3,3a,4,5,5,5a,5b,6Decachlorooctahydro1,3,4metheno2Hcyclobuta(cd)pentalen2one
    • 1,2,3,4,5,5,6,7,8,9,10,10Dodecachlorooctahydro1,3,4metheno2cyclobuta(c,d)pentalone
    • 1,2,3,5,6,7,8,9,10,10-decachloro(5.2.1.0(2,6).0(3,9).0(5,8))decano-4-one
    • 1,3,4Metheno2Hcyclobuta(cd)pentalen2one, 1,1a,3,3a,4,5,5,5a,5b,6decachlorooctahydro

  • Applications

    Chlordecone, CAS 143-50-0, was historically used as a broad-spectrum organochlorine pesticide in tropical agriculture, primarily for crops such as bananas, plantains, cacao, and palm oil, applied as soil treatments or foliar sprays to control pests; today, due to its persistence and toxicity, it is restricted or banned in many jurisdictions and is referenced in regulatory frameworks and safety assessments; beyond agriculture, it is treated as a persistent organic pollutant of environmental concern and a focus of environmental monitoring and risk assessment, with analyses of soil, water, and biota to understand its fate and bioaccumulation; it is also cited in research on remediation strategies and contaminated-site management.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 12.53
    methanol 17.98
    isopropanol 10.18
    water 0.64
    ethyl acetate 51.9
    n-propanol 14.37
    acetone 60.41
    n-butanol 12.64
    acetonitrile 37.33
    DMF 180.85
    toluene 58.76
    isobutanol 11.97
    1,4-dioxane 106.81
    methyl acetate 55.66
    THF 172.17
    2-butanone 58.2
    n-pentanol 12.37
    sec-butanol 13.12
    n-hexane 4.01
    ethylene glycol 13.34
    NMP 222.1
    cyclohexane 10.67
    DMSO 87.75
    n-butyl acetate 44.2
    n-octanol 20.06
    chloroform 99.04
    n-propyl acetate 42.37
    acetic acid 20.2
    dichloromethane 94.8
    cyclohexanone 99.27
    propylene glycol 9.83
    isopropyl acetate 50.75
    DMAc 181.12
    2-ethoxyethanol 41.5
    isopentanol 12.41
    n-heptane 8.19
    ethyl formate 34.57
    1,2-dichloroethane 52.91
    n-hexanol 20.19
    2-methoxyethanol 61.67
    isobutyl acetate 31.3
    tetrachloromethane 22.0
    n-pentyl acetate 37.95
    transcutol 75.91
    n-heptanol 17.91
    ethylbenzene 35.51
    MIBK 47.37
    2-propoxyethanol 65.02
    tert-butanol 12.91
    MTBE 28.1
    2-butoxyethanol 38.39
    propionic acid 20.26
    o-xylene 49.44
    formic acid 19.74
    diethyl ether 40.64
    m-xylene 47.95
    p-xylene 44.68
    chlorobenzene 45.41
    dimethyl carbonate 71.94
    n-octane 5.05
    formamide 44.84
    cyclopentanone 134.82
    2-pentanone 54.92
    anisole 67.44
    cyclopentyl methyl ether 95.64
    gamma-butyrolactone 131.17
    1-methoxy-2-propanol 56.41
    pyridine 94.33
    3-pentanone 64.46
    furfural 139.85
    n-dodecane 4.67
    diethylene glycol 55.19
    diisopropyl ether 24.48
    tert-amyl alcohol 15.06
    acetylacetone 105.68
    n-hexadecane 5.7
    acetophenone 79.06
    methyl propionate 67.18
    isopentyl acetate 40.37
    trichloroethylene 117.2
    n-nonanol 21.42
    cyclohexanol 26.7
    benzyl alcohol 38.14
    2-ethylhexanol 21.38
    isooctanol 15.88
    dipropyl ether 44.42
    1,2-dichlorobenzene 48.47
    ethyl lactate 36.88
    propylene carbonate 75.25
    n-methylformamide 65.1
    2-pentanol 13.07
    n-pentane 4.28
    1-propoxy-2-propanol 52.35
    1-methoxy-2-propyl acetate 81.28
    2-(2-methoxypropoxy) propanol 55.22
    mesitylene 35.77
    ε-caprolactone 87.34
    p-cymene 32.25
    epichlorohydrin 119.33
    1,1,1-trichloroethane 48.52
    2-aminoethanol 16.03
    morpholine-4-carbaldehyde 195.92
    sulfolane 147.06
    2,2,4-trimethylpentane 3.72
    2-methyltetrahydrofuran 89.52
    n-hexyl acetate 43.63
    isooctane 2.86
    2-(2-butoxyethoxy)ethanol 51.26
    sec-butyl acetate 39.43
    tert-butyl acetate 56.33
    decalin 7.88
    glycerin 23.21
    diglyme 101.17
    acrylic acid 26.71
    isopropyl myristate 30.34
    n-butyric acid 23.83
    acetyl acetate 54.36
    di(2-ethylhexyl) phthalate 27.89
    ethyl propionate 54.76
    nitromethane 84.86
    1,2-diethoxyethane 50.24
    benzonitrile 54.17
    trioctyl phosphate 21.19
    1-bromopropane 31.75
    gamma-valerolactone 179.64
    n-decanol 17.5
    triethyl phosphate 36.27
    4-methyl-2-pentanol 12.19
    propionitrile 33.63
    vinylene carbonate 77.35
    1,1,2-trichlorotrifluoroethane 105.16
    DMS 63.03
    cumene 24.36
    2-octanol 16.89
    2-hexanone 45.83
    octyl acetate 32.82
    limonene 37.99
    1,2-dimethoxyethane 107.41
    ethyl orthosilicate 34.61
    tributyl phosphate 23.43
    diacetone alcohol 50.12
    N,N-dimethylaniline 61.04
    acrylonitrile 52.98
    aniline 46.98
    1,3-propanediol 18.13
    bromobenzene 52.78
    dibromomethane 57.58
    1,1,2,2-tetrachloroethane 85.61
    2-methyl-cyclohexyl acetate 50.98
    tetrabutyl urea 42.46
    diisobutyl methanol 17.6
    2-phenylethanol 45.45
    styrene 36.31
    dioctyl adipate 40.54
    dimethyl sulfate 110.28
    ethyl butyrate 48.71
    methyl lactate 53.92
    butyl lactate 34.57
    diethyl carbonate 35.68
    propanediol butyl ether 30.44
    triethyl orthoformate 43.95
    p-tert-butyltoluene 30.51
    methyl 4-tert-butylbenzoate 60.82
    morpholine 95.56
    tert-butylamine 9.26
    n-dodecanol 14.7
    dimethoxymethane 147.23
    ethylene carbonate 60.35
    cyrene 83.94
    2-ethoxyethyl acetate 51.76
    2-ethylhexyl acetate 40.82
    1,2,4-trichlorobenzene 63.25
    4-methylpyridine 86.39
    dibutyl ether 29.06
    2,6-dimethyl-4-heptanol 17.6
    DEF 96.84
    dimethyl isosorbide 130.55
    tetrachloroethylene 67.73
    eugenol 60.33
    triacetin 60.15
    span 80 39.6
    1,4-butanediol 11.65
    1,1-dichloroethane 39.24
    2-methyl-1-pentanol 13.12
    methyl formate 63.84
    2-methyl-1-butanol 13.41
    n-decane 7.64
    butyronitrile 28.97
    3,7-dimethyl-1-octanol 20.3
    1-chlorooctane 20.16
    1-chlorotetradecane 11.32
    n-nonane 6.66
    undecane 5.84
    tert-butylcyclohexane 5.5
    cyclooctane 7.39
    cyclopentanol 33.53
    tetrahydropyran 68.03
    tert-amyl methyl ether 36.34
    2,5,8-trioxanonane 83.71
    1-hexene 11.38
    2-isopropoxyethanol 34.49
    2,2,2-trifluoroethanol 26.83
    methyl butyrate 56.53

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction