Cetyl Palmitate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    540-10-3

    Molecular formula
    C32H64O2

    SMILES
    CCCCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCCCC

    Safety labels

  • Odor profile

    Fragrance
    Waxy 77.53%
    Fatty 64.06%
    Oily 54.03%
    Odorless 32.55%
    Sweet 23.51%
    Creamy 23.1%
    Dairy 18.32%
    Clean 17.53%
    Fruity 16.69%
    Balsamic 16.43%

     

    Flavor
    Waxy 61.98%
    Fatty 42.52%
    Mild 42.01%
    Oily 36.44%
    Alkane 33.28%
    Bland 32.85%
    Fat 29.79%
    Faint 29.31%
    Coconut 26.48%
    Soapy 26.4%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    15.2

    pKa est.
    8.87 (weak base)

    Molecular weight
    480.8 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    524°C

    Flash point

    • 236.05 ˚C est.

  • Synonyms

    • Cetyl palmitate
    • Palmityl palmitate
    • 540-10-3
    • Hexadecyl hexadecanoate
    • Hexadecanoic acid, hexadecyl ester
    • n-Hexadecyl hexadecanoate
    • PALMITIC ACID, HEXADECYL ESTER
    • 5ZA2S6B08X
    • WE(16:0/16:0)
    • DTXSID5047114
    • CHEBI:75584
    • RefChem:918287
    • DTXCID3027114
    • 208-736-6
    • Hexadecyl palmitate
    • Cetin
    • Hexadecanoic acid hexadecyl ester
    • hexadecanyl hexadecanoate
    • Standamul 1616
    • MFCD00053739
    • Cetyl palmitate [NF]
    • C32H64O2
    • palmitic acid, cetyl ester
    • 95912-87-1
    • Cetyl palmitate (NF)
    • 100231-74-1
    • Palmitic Acid Hexadecyl Ester
    • n-hexadecyl palmitate
    • EINECS 208-736-6
    • Palmitic acid palmityl ester
    • BRN 1805188
    • UNII-5ZA2S6B08X
    • Schercemol CP
    • Crodamol CP
    • Precifac ATO
    • Starfol CP
    • Cutina CP
    • EINECS 309-375-8
    • Waxenol 815
    • Kessco 653
    • n-hexadecanyl palmitate
    • Radia 7500
    • Cetyl palmitate 15 CRS
    • Cetyl palmitate 95 CRS
    • SCHEMBL44487
    • CETYL PALMITATE [II]
    • CETYL PALMITATE [MI]
    • N-HEXYLDECYL PALMITATE
    • Palmityl palmitate, >=99%
    • Palmatic acid n-hexadecyl ester
    • CETYL PALMITATE [VANDF]
    • CETYL PALMITATE [MART.]
    • CHEMBL2106073
    • CETYL PALMITATE [USP-RS]
    • CETYL PALMITATE [WHO-DD]
    • MSK2051
    • YFC06615
    • EINECS 306-083-2
    • Hexadecyl ester of hexadecanoic acid
    • LMFA07010001
    • SBB058698
    • AKOS015903369
    • CETYL PALMITATE [EP MONOGRAPH]
    • CS-W011523
    • HY-W010807
    • DS-11394
    • SY010863
    • DB-052456
    • NS00012089
    • P1077
    • ST51037392
    • D08888
    • D70209
    • EC 306-083-2
    • F791126
    • Q409361
    • Cetyl palmitate 15, European Pharmacopoeia (EP) Reference Standard
    • Cetyl palmitate 95, European Pharmacopoeia (EP) Reference Standard
    • Cetyl palmitate, United States Pharmacopeia (USP) Reference Standard
    • Cetyl Palmitate, Pharmaceutical Secondary Standard; Certified Reference Material
    • 540-10-3

  • Applications

    Cetyl Palmitate (CAS 540-10-3) is a fatty ester widely used in cosmetic and personal-care formulations as an emollient and thickening agent, providing slip and improving texture in creams, lotions, and lip products. It also serves as a conditioning ingredient in hair-care formulas, helping to soften and detangle. In makeup, it contributes to smoothness and glide in lipsticks and other color cosmetics. In household products, it can function as a texture modifier and wax-like carrier for fragrances and actives in creams and polishes. In pharmaceuticals, it may be used as an excipient/vehicle for topical dosage forms. Altogether, cetyl palmitate is typically employed to soften, stabilize, and modify viscosity and feel across personal care, household, and pharmaceutical applications.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 4.89
    methanol 6.51
    isopropanol 5.69
    water 0.08
    ethyl acetate 119.61
    n-propanol 9.76
    acetone 51.79
    n-butanol 12.69
    acetonitrile 18.33
    DMF 85.23
    toluene 51.76
    isobutanol 11.99
    1,4-dioxane 109.85
    methyl acetate 66.66
    THF 300.45
    2-butanone 91.34
    n-pentanol 14.28
    sec-butanol 15.25
    n-hexane 17.36
    ethylene glycol 0.88
    NMP 481.95
    cyclohexane 104.29
    DMSO 111.97
    n-butyl acetate 154.19
    n-octanol 41.41
    chloroform 464.53
    n-propyl acetate 156.91
    acetic acid 30.06
    dichloromethane 483.33
    cyclohexanone 418.43
    propylene glycol 2.52
    isopropyl acetate 133.13
    DMAc 277.82
    2-ethoxyethanol 36.36
    isopentanol 21.27
    n-heptane 23.52
    ethyl formate 45.26
    1,2-dichloroethane 269.68
    n-hexanol 15.39
    2-methoxyethanol 29.61
    isobutyl acetate 112.5
    tetrachloromethane 136.13
    n-pentyl acetate 329.52
    transcutol 329.68
    n-heptanol 32.29
    ethylbenzene 49.14
    MIBK 112.92
    2-propoxyethanol 42.34
    tert-butanol 17.98
    MTBE 69.75
    2-butoxyethanol 87.09
    propionic acid 32.92
    o-xylene 63.62
    formic acid 6.64
    diethyl ether 47.11
    m-xylene 46.59
    p-xylene 78.81
    chlorobenzene 125.03
    dimethyl carbonate 39.38
    n-octane 14.24
    formamide 14.49
    cyclopentanone 373.06
    2-pentanone 99.34
    anisole 94.53
    cyclopentyl methyl ether 212.04
    gamma-butyrolactone 357.68
    1-methoxy-2-propanol 37.45
    pyridine 147.09
    3-pentanone 113.22
    furfural 242.93
    n-dodecane 6.82
    diethylene glycol 13.9
    diisopropyl ether 42.43
    tert-amyl alcohol 37.96
    acetylacetone 178.09
    n-hexadecane 8.64
    acetophenone 158.38
    methyl propionate 86.72
    isopentyl acetate 172.78
    trichloroethylene 523.25
    n-nonanol 46.48
    cyclohexanol 62.61
    benzyl alcohol 38.4
    2-ethylhexanol 34.64
    isooctanol 41.86
    dipropyl ether 108.68
    1,2-dichlorobenzene 205.29
    ethyl lactate 54.34
    propylene carbonate 241.7
    n-methylformamide 28.44
    2-pentanol 15.17
    n-pentane 9.17
    1-propoxy-2-propanol 64.92
    1-methoxy-2-propyl acetate 160.87
    2-(2-methoxypropoxy) propanol 110.51
    mesitylene 45.85
    ε-caprolactone 387.25
    p-cymene 55.51
    epichlorohydrin 340.39
    1,1,1-trichloroethane 390.23
    2-aminoethanol 3.57
    morpholine-4-carbaldehyde 226.14
    sulfolane 705.88
    2,2,4-trimethylpentane 17.29
    2-methyltetrahydrofuran 262.26
    n-hexyl acetate 278.02
    isooctane 8.02
    2-(2-butoxyethoxy)ethanol 121.46
    sec-butyl acetate 145.46
    tert-butyl acetate 220.15
    decalin 38.54
    glycerin 6.35
    diglyme 367.75
    acrylic acid 25.22
    isopropyl myristate 89.7
    n-butyric acid 79.76
    acetyl acetate 111.56
    di(2-ethylhexyl) phthalate 67.16
    ethyl propionate 154.39
    nitromethane 93.32
    1,2-diethoxyethane 197.45
    benzonitrile 68.35
    trioctyl phosphate 48.6
    1-bromopropane 135.8
    gamma-valerolactone 460.53
    n-decanol 27.99
    triethyl phosphate 142.09
    4-methyl-2-pentanol 17.23
    propionitrile 26.41
    vinylene carbonate 174.75
    1,1,2-trichlorotrifluoroethane 221.25
    DMS 127.31
    cumene 41.51
    2-octanol 39.91
    2-hexanone 122.25
    octyl acetate 102.73
    limonene 102.13
    1,2-dimethoxyethane 151.4
    ethyl orthosilicate 139.51
    tributyl phosphate 74.41
    diacetone alcohol 129.58
    N,N-dimethylaniline 83.71
    acrylonitrile 27.97
    aniline 42.13
    1,3-propanediol 7.99
    bromobenzene 179.03
    dibromomethane 283.12
    1,1,2,2-tetrachloroethane 532.17
    2-methyl-cyclohexyl acetate 203.56
    tetrabutyl urea 121.75
    diisobutyl methanol 37.86
    2-phenylethanol 37.96
    styrene 55.4
    dioctyl adipate 163.94
    dimethyl sulfate 125.88
    ethyl butyrate 209.97
    methyl lactate 35.62
    butyl lactate 161.77
    diethyl carbonate 122.49
    propanediol butyl ether 60.6
    triethyl orthoformate 197.19
    p-tert-butyltoluene 50.21
    methyl 4-tert-butylbenzoate 231.67
    morpholine 126.05
    tert-butylamine 16.15
    n-dodecanol 19.21
    dimethoxymethane 60.45
    ethylene carbonate 157.81
    cyrene 130.19
    2-ethoxyethyl acetate 290.89
    2-ethylhexyl acetate 173.33
    1,2,4-trichlorobenzene 260.45
    4-methylpyridine 141.92
    dibutyl ether 156.81
    2,6-dimethyl-4-heptanol 37.86
    DEF 170.94
    dimethyl isosorbide 331.31
    tetrachloroethylene 326.93
    eugenol 140.99
    triacetin 319.93
    span 80 110.92
    1,4-butanediol 4.76
    1,1-dichloroethane 193.09
    2-methyl-1-pentanol 25.65
    methyl formate 25.57
    2-methyl-1-butanol 22.16
    n-decane 18.14
    butyronitrile 32.38
    3,7-dimethyl-1-octanol 51.73
    1-chlorooctane 81.25
    1-chlorotetradecane 22.73
    n-nonane 17.88
    undecane 10.23
    tert-butylcyclohexane 25.1
    cyclooctane 31.08
    cyclopentanol 55.23
    tetrahydropyran 189.82
    tert-amyl methyl ether 98.98
    2,5,8-trioxanonane 194.8
    1-hexene 30.67
    2-isopropoxyethanol 39.06
    2,2,2-trifluoroethanol 26.61
    methyl butyrate 211.56

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction