Cetyl Lactate

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  • Identifiers

    CAS number
    35274-05-6

    Molecular formula
    C19H38O3

    SMILES
    CCCCCCCCCCCCCCCCOC(=O)C(C)O

  • Odor profile

    Fragrance
    Fatty 70.65%
    Waxy 64.7%
    Oily 53.8%
    Creamy 36.9%
    Fruity 34.74%
    Buttery 33.78%
    Sweet 31.58%
    Dairy 31.49%
    Milky 30.08%
    Odorless 30.02%

     

    Flavor
    Waxy 66.62%
    Oily 48.82%
    Fatty 46.12%
    Mild 43.88%
    Soapy 37.88%
    Creamy 33.3%
    Fat 30.22%
    Bland 29.87%
    Coconut 29.55%
    Fruity 28.44%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.6

    pKa est.
    7.11 (neutral)

    Molecular weight
    314.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    384°C

    Flash point

    • 169.03 ˚C est.

    Solubility expt.

    • Practically insoluble or insoluble in water
    • Soluble (in ethanol)

  • Synonyms

    • CETYL LACTATE
    • 35274-05-6
    • hexadecyl 2-hydroxypropanoate
    • Hexadecyl lactate
    • Propanoic acid, 2-hydroxy-, hexadecyl ester
    • UNII-A7EVH2RK4O
    • A7EVH2RK4O
    • Ceraphyl 28
    • n-Hexadecyl lactate
    • UNIESTER LC
    • CETINOL LA
    • DERMOL CL
    • DUB LC
    • AEC CETYL LACTATE
    • LACTABASE C16
    • EINECS 252-478-7
    • Lactic acid hexadecyl ester
    • NIKKOL CETYL LACTATE
    • CETYL LACTATE [MI]
    • Hexadecyl 2-Hydroxypropionate
    • AI3-14483
    • (+/-)-CETYL LACTATE
    • n-Hexadecyl-2-hydroxypropanoate
    • FEMA NO. 4483
    • DTXSID20865759
    • CETYL LACTATE, (+/-)-
    • LACTIC ACID, HEXADECYL ESTER
    • MFCD00152336
    • SCHEMBL33964
    • CETYL LACTATE [INCI]
    • hexadecyl lactate, AldrichCPR
    • DTXCID40814128
    • AKOS027321017
    • 2-Hydroxypropionic acid hexadecyl ester
    • CS-0365270
    • H1159
    • NS00001810
    • Q27273721
    • 252-478-7

  • Applications

    Cetyl lactate (CAS 35274-05-6) is widely used in cosmetics and personal care as an emollient and conditioning agent, providing slip and a light, non-greasy feel in creams, lotions, and hair-care products. It often serves as a co-emollient and texture enhancer in emulsions to improve spreadability and skin feel. It can function as a mild surfactant or as part of a surfactant-emollient blend in cleansing formulations, contributing gentle cleansing while helping to maintain moisturization. Additionally, it is used as a processing aid and lubricating component in cosmetic matrices to assist manufacturing and formulation stability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 67.66
    methanol 102.51
    isopropanol 100.36
    water 0.06
    ethyl acetate 502.61
    n-propanol 104.97
    acetone 297.1
    n-butanol 129.71
    acetonitrile 122.87
    DMF 451.65
    toluene 145.31
    isobutanol 117.69
    1,4-dioxane 430.14
    methyl acetate 288.04
    THF 1039.19
    2-butanone 406.82
    n-pentanol 115.29
    sec-butanol 145.32
    n-hexane 46.73
    ethylene glycol 6.76
    NMP 901.65
    cyclohexane 260.66
    DMSO 697.95
    n-butyl acetate 548.07
    n-octanol 150.04
    chloroform 892.91
    n-propyl acetate 651.13
    acetic acid 151.47
    dichloromethane 976.09
    cyclohexanone 1244.48
    propylene glycol 21.96
    isopropyl acetate 483.35
    DMAc 727.31
    2-ethoxyethanol 270.05
    isopentanol 191.72
    n-heptane 53.87
    ethyl formate 212.35
    1,2-dichloroethane 806.16
    n-hexanol 105.99
    2-methoxyethanol 265.38
    isobutyl acetate 391.1
    tetrachloromethane 260.89
    n-pentyl acetate 809.48
    transcutol 1270.7
    n-heptanol 138.53
    ethylbenzene 124.45
    MIBK 461.09
    2-propoxyethanol 244.2
    tert-butanol 240.43
    MTBE 389.82
    2-butoxyethanol 359.05
    propionic acid 161.92
    o-xylene 155.26
    formic acid 31.16
    diethyl ether 293.11
    m-xylene 131.01
    p-xylene 194.48
    chlorobenzene 268.7
    dimethyl carbonate 109.09
    n-octane 30.63
    formamide 82.71
    cyclopentanone 1082.34
    2-pentanone 491.65
    anisole 256.37
    cyclopentyl methyl ether 636.87
    gamma-butyrolactone 930.72
    1-methoxy-2-propanol 289.17
    pyridine 434.99
    3-pentanone 401.12
    furfural 613.9
    n-dodecane 14.65
    diethylene glycol 96.65
    diisopropyl ether 169.19
    tert-amyl alcohol 275.01
    acetylacetone 598.13
    n-hexadecane 18.28
    acetophenone 362.38
    methyl propionate 332.57
    isopentyl acetate 527.85
    trichloroethylene 1184.46
    n-nonanol 147.62
    cyclohexanol 359.23
    benzyl alcohol 154.99
    2-ethylhexanol 145.26
    isooctanol 161.93
    dipropyl ether 325.71
    1,2-dichlorobenzene 366.95
    ethyl lactate 187.17
    propylene carbonate 529.01
    n-methylformamide 164.69
    2-pentanol 141.48
    n-pentane 33.06
    1-propoxy-2-propanol 301.56
    1-methoxy-2-propyl acetate 439.68
    2-(2-methoxypropoxy) propanol 252.52
    mesitylene 115.49
    ε-caprolactone 1016.76
    p-cymene 116.01
    epichlorohydrin 982.09
    1,1,1-trichloroethane 806.78
    2-aminoethanol 31.26
    morpholine-4-carbaldehyde 692.42
    sulfolane 1539.54
    2,2,4-trimethylpentane 41.94
    2-methyltetrahydrofuran 805.65
    n-hexyl acetate 639.86
    isooctane 24.79
    2-(2-butoxyethoxy)ethanol 393.1
    sec-butyl acetate 488.25
    tert-butyl acetate 660.98
    decalin 79.23
    glycerin 42.9
    diglyme 994.9
    acrylic acid 103.0
    isopropyl myristate 184.16
    n-butyric acid 411.51
    acetyl acetate 310.26
    di(2-ethylhexyl) phthalate 124.8
    ethyl propionate 497.11
    nitromethane 415.59
    1,2-diethoxyethane 598.22
    benzonitrile 240.0
    trioctyl phosphate 111.03
    1-bromopropane 432.97
    gamma-valerolactone 1313.89
    n-decanol 89.14
    triethyl phosphate 225.67
    4-methyl-2-pentanol 120.51
    propionitrile 157.97
    vinylene carbonate 376.88
    1,1,2-trichlorotrifluoroethane 589.85
    DMS 295.74
    cumene 99.7
    2-octanol 153.58
    2-hexanone 474.61
    octyl acetate 229.64
    limonene 230.63
    1,2-dimethoxyethane 743.8
    ethyl orthosilicate 231.86
    tributyl phosphate 157.61
    diacetone alcohol 502.58
    N,N-dimethylaniline 191.9
    acrylonitrile 162.98
    aniline 146.45
    1,3-propanediol 80.79
    bromobenzene 330.31
    dibromomethane 640.77
    1,1,2,2-tetrachloroethane 1218.81
    2-methyl-cyclohexyl acetate 380.31
    tetrabutyl urea 232.38
    diisobutyl methanol 125.82
    2-phenylethanol 140.47
    styrene 143.83
    dioctyl adipate 289.52
    dimethyl sulfate 258.18
    ethyl butyrate 521.43
    methyl lactate 131.78
    butyl lactate 403.57
    diethyl carbonate 256.63
    propanediol butyl ether 256.58
    triethyl orthoformate 374.06
    p-tert-butyltoluene 110.09
    methyl 4-tert-butylbenzoate 392.23
    morpholine 628.73
    tert-butylamine 160.69
    n-dodecanol 61.49
    dimethoxymethane 300.29
    ethylene carbonate 384.06
    cyrene 287.98
    2-ethoxyethyl acetate 707.37
    2-ethylhexyl acetate 457.56
    1,2,4-trichlorobenzene 415.86
    4-methylpyridine 425.4
    dibutyl ether 408.03
    2,6-dimethyl-4-heptanol 125.82
    DEF 661.37
    dimethyl isosorbide 570.82
    tetrachloroethylene 822.69
    eugenol 280.8
    triacetin 565.04
    span 80 258.78
    1,4-butanediol 38.99
    1,1-dichloroethane 591.45
    2-methyl-1-pentanol 156.57
    methyl formate 118.9
    2-methyl-1-butanol 166.01
    n-decane 37.99
    butyronitrile 218.08
    3,7-dimethyl-1-octanol 159.35
    1-chlorooctane 190.32
    1-chlorotetradecane 50.4
    n-nonane 38.84
    undecane 21.54
    tert-butylcyclohexane 57.14
    cyclooctane 58.86
    cyclopentanol 314.31
    tetrahydropyran 746.5
    tert-amyl methyl ether 359.66
    2,5,8-trioxanonane 503.53
    1-hexene 120.1
    2-isopropoxyethanol 245.79
    2,2,2-trifluoroethanol 85.41
    methyl butyrate 739.2

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction