Cetyl glycol isostearate

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  • Identifiers

    CAS number
    245485-83-0

    Molecular formula
    C34H68O3

    SMILES
    CCCCCCCCCCCCCCC(COC(=O)CCCCCCCCCCCCCCC(C)C)O

    Safety labels

  • Odor profile

    Fragrance
    Waxy 75.73%
    Fatty 57.63%
    Oily 44.49%
    Odorless 37.45%
    Creamy 21.03%
    Sweet 17.46%
    Milky 17.38%
    Fishy 16.78%
    Balsamic 16.58%
    Savory 16.46%

     

    Flavor
    Waxy 47.82%
    Mild 41.46%
    Fatty 40.36%
    Bland 38.01%
    Oily 35.51%
    Faint 32.3%
    Fat 28.47%
    Odorless 26.06%
    Slightly waxy 24.86%
    Delicate 23.2%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    14.8

    pKa est.
    9.29 (weak base)

    Molecular weight
    524.9 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    621°C

    Flash point

    • 238.85 ˚C est.

  • Synonyms

    • Cetyl glycol isostearate
    • Cetyl glycol 1-isostearate
    • UNII-L40H81G410
    • Cetyl glycol isostearate [INCI]
    • Isooctadecanoic acid, 2-hydroxyhexadecyl ester
    • L40H81G410
    • Heptadecanoic acid, 16-methyl-, 2-hydroxyhexadecyl ester
    • 245485-83-0
    • RefChem:124713
    • (+-)-CETYL GLYCOL 1-ISOSTEARATE
    • CETYL GLYCOL 1-ISOSTEARATE, (+-)-
    • (+/-)-Cetyl glycol 1-isostearate
    • Cetyl glycol 1-isostearate, (+/-)-
    • SCHEMBL29369638
    • DTXSID801021699
    • Q27282664
    • 247232-39-9
    • 247232-39-9

  • Applications

    Cetyl glycol isostearate (CAS 245485-83-0) is used primarily in cosmetics and personal care as an emollient and conditioning agent, delivering skin and hair conditioning and improving spread and texture in creams, lotions, and makeup. It also serves as a texture enhancer and thickener in emulsions and can act as a conditioning agent in hair care formulations. Additionally, it may function as a co-emulsifier or stabilizer in cosmetic formulations and can act as a lubricating agent or plasticizer in select polymer or coating applications to improve slip during processing. It may serve as a carrier for fragrances or active ingredients in some formulations. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.47
    methanol 3.17
    isopropanol 2.5
    water 0.03
    ethyl acetate 43.31
    n-propanol 4.3
    acetone 20.92
    n-butanol 5.24
    acetonitrile 5.77
    DMF 36.26
    toluene 19.75
    isobutanol 4.76
    1,4-dioxane 45.72
    methyl acetate 25.28
    THF 150.35
    2-butanone 35.74
    n-pentanol 6.69
    sec-butanol 6.28
    n-hexane 5.12
    ethylene glycol 0.38
    NMP 203.89
    cyclohexane 23.78
    DMSO 54.41
    n-butyl acetate 60.91
    n-octanol 19.93
    chloroform 173.11
    n-propyl acetate 59.09
    acetic acid 14.16
    dichloromethane 164.69
    cyclohexanone 157.36
    propylene glycol 1.22
    isopropyl acetate 51.93
    DMAc 136.11
    2-ethoxyethanol 18.46
    isopentanol 8.65
    n-heptane 6.76
    ethyl formate 17.6
    1,2-dichloroethane 92.26
    n-hexanol 7.07
    2-methoxyethanol 14.76
    isobutyl acetate 45.01
    tetrachloromethane 42.34
    n-pentyl acetate 139.47
    transcutol 210.4
    n-heptanol 15.46
    ethylbenzene 19.94
    MIBK 46.07
    2-propoxyethanol 22.7
    tert-butanol 7.71
    MTBE 29.49
    2-butoxyethanol 48.27
    propionic acid 12.66
    o-xylene 24.09
    formic acid 3.08
    diethyl ether 17.3
    m-xylene 18.38
    p-xylene 28.9
    chlorobenzene 44.93
    dimethyl carbonate 16.77
    n-octane 4.39
    formamide 5.99
    cyclopentanone 156.31
    2-pentanone 38.61
    anisole 39.77
    cyclopentyl methyl ether 87.11
    gamma-butyrolactone 151.85
    1-methoxy-2-propanol 19.18
    pyridine 54.33
    3-pentanone 43.48
    furfural 105.52
    n-dodecane 2.35
    diethylene glycol 7.39
    diisopropyl ether 15.6
    tert-amyl alcohol 16.02
    acetylacetone 77.92
    n-hexadecane 2.9
    acetophenone 65.11
    methyl propionate 35.01
    isopentyl acetate 72.21
    trichloroethylene 193.45
    n-nonanol 23.25
    cyclohexanol 22.67
    benzyl alcohol 16.65
    2-ethylhexanol 14.79
    isooctanol 20.6
    dipropyl ether 40.01
    1,2-dichlorobenzene 71.22
    ethyl lactate 24.7
    propylene carbonate 100.86
    n-methylformamide 11.29
    2-pentanol 6.23
    n-pentane 2.63
    1-propoxy-2-propanol 35.26
    1-methoxy-2-propyl acetate 78.27
    2-(2-methoxypropoxy) propanol 64.19
    mesitylene 16.95
    ε-caprolactone 162.54
    p-cymene 21.87
    epichlorohydrin 142.73
    1,1,1-trichloroethane 135.11
    2-aminoethanol 1.61
    morpholine-4-carbaldehyde 100.41
    sulfolane 322.82
    2,2,4-trimethylpentane 6.16
    2-methyltetrahydrofuran 109.66
    n-hexyl acetate 118.99
    isooctane 2.72
    2-(2-butoxyethoxy)ethanol 73.27
    sec-butyl acetate 59.44
    tert-butyl acetate 97.67
    decalin 12.39
    glycerin 3.15
    diglyme 203.06
    acrylic acid 9.68
    isopropyl myristate 36.91
    n-butyric acid 32.93
    acetyl acetate 42.64
    di(2-ethylhexyl) phthalate 30.66
    ethyl propionate 58.88
    nitromethane 41.22
    1,2-diethoxyethane 89.62
    benzonitrile 25.51
    trioctyl phosphate 21.31
    1-bromopropane 44.71
    gamma-valerolactone 210.82
    n-decanol 13.36
    triethyl phosphate 58.82
    4-methyl-2-pentanol 7.83
    propionitrile 8.54
    vinylene carbonate 71.24
    1,1,2-trichlorotrifluoroethane 102.69
    DMS 53.6
    cumene 16.78
    2-octanol 18.31
    2-hexanone 51.47
    octyl acetate 43.05
    limonene 39.47
    1,2-dimethoxyethane 71.07
    ethyl orthosilicate 59.4
    tributyl phosphate 32.32
    diacetone alcohol 64.87
    N,N-dimethylaniline 36.33
    acrylonitrile 9.21
    aniline 15.54
    1,3-propanediol 3.77
    bromobenzene 61.08
    dibromomethane 95.25
    1,1,2,2-tetrachloroethane 203.6
    2-methyl-cyclohexyl acetate 85.45
    tetrabutyl urea 51.74
    diisobutyl methanol 16.06
    2-phenylethanol 17.33
    styrene 20.46
    dioctyl adipate 70.31
    dimethyl sulfate 56.58
    ethyl butyrate 79.47
    methyl lactate 16.85
    butyl lactate 79.59
    diethyl carbonate 45.55
    propanediol butyl ether 36.3
    triethyl orthoformate 83.45
    p-tert-butyltoluene 21.04
    methyl 4-tert-butylbenzoate 113.76
    morpholine 54.4
    tert-butylamine 6.41
    n-dodecanol 8.69
    dimethoxymethane 28.35
    ethylene carbonate 62.11
    cyrene 68.5
    2-ethoxyethyl acetate 143.62
    2-ethylhexyl acetate 69.41
    1,2,4-trichlorobenzene 96.79
    4-methylpyridine 51.52
    dibutyl ether 62.41
    2,6-dimethyl-4-heptanol 16.06
    DEF 64.85
    dimethyl isosorbide 185.46
    tetrachloroethylene 119.59
    eugenol 70.81
    triacetin 150.08
    span 80 58.05
    1,4-butanediol 2.21
    1,1-dichloroethane 66.78
    2-methyl-1-pentanol 11.85
    methyl formate 10.57
    2-methyl-1-butanol 9.05
    n-decane 6.26
    butyronitrile 11.07
    3,7-dimethyl-1-octanol 25.4
    1-chlorooctane 30.72
    1-chlorotetradecane 8.27
    n-nonane 5.95
    undecane 3.52
    tert-butylcyclohexane 8.88
    cyclooctane 7.98
    cyclopentanol 20.34
    tetrahydropyran 71.67
    tert-amyl methyl ether 41.99
    2,5,8-trioxanonane 106.04
    1-hexene 11.07
    2-isopropoxyethanol 19.63
    2,2,2-trifluoroethanol 11.32
    methyl butyrate 80.62

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction