Carbofuran

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  • Identifiers

    CAS number
    1563-66-2

    Molecular formula
    C12H15NO3

    SMILES
    CC1(CC2=C(O1)C(=CC=C2)OC(=O)NC)C

    Safety labels

    Acute Toxic
    Acute Toxic

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 43.79%
    Animal 23.88%
    Savory 23.42%
    Musk 22.21%
    Grape 21.15%
    Fruity 21.15%
    Phenolic 20.22%
    Milky 19.88%
    Dry 19.78%
    Cooling 19.58%

     

    Flavor
    Bitter 35.8%
    Woody 28.29%
    Fruity 26.66%
    Odorless 24.73%
    Powdery 24.37%
    Sweet 22.41%
    Herbal 22.3%
    Mild 22.03%
    Spice 21.66%
    Bland 21.38%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.3

    pKa est.
    8.86 (weak base)

    Molecular weight
    221.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point est.
    324°C

    Melting point expt.

    • 302 to 307 °F (EPA, 1998)
    • 153.2 °C
    • Melting point = 153-154 °C (pure); 150-152 °C (technical)
    • 150 - 152 °C
    • 153 °C
    • 304 °F

    Flash point

    • 148.26 ˚C est.

    Solubility expt.

    • 0.07 % at 77 °F (NIOSH, 2024)
    • In water, 351 mg/L at 25 °C
    • In dichloromethane >200, isopropanol 20-50, toluene 10-20 (all in g/L, 20 °C)
    • Unstable in alkaline media. Stable in acidic and neutral media.
    • Highly soluble in N-methyl-2-pyrrolidone, dimethylformamide, dimethyl sulfoxide, acetone, acetonitrile, methylene chloride, cyclohexanone, benzene, xylene
    • 150 g/kg acetone, 140 g/kg acetonitrile, 120 g/kg dichloromethane, 90 g/kg cyclohexanone, 40 g/kg benzene
    • 0.32 mg/mL at 25 °C
    • Solubility in water, g/100ml at 25 °C: 0.07
    • (77 °F): 0.07%

  • Synonyms

    • carbofuran
    • 1563-66-2
    • Furadan
    • Curaterr
    • Chinufur
    • Furacarb
    • Yaltox
    • Furadan 3G
    • Crisfuran
    • Furadan G
    • Furadan 4f
    • Carbofurane
    • Pillarfuran
    • Kenofuran
    • Niagara 10242
    • BAY 70143
    • Karbofuranu
    • Brifur
    • Furodan
    • FMC 10242
    • Niagara nia-10242
    • Bayer 70143
    • NIA 10242
    • Carbodan
    • Furadane
    • Karbofuranu [Polish]
    • Me f248
    • OMS 864
    • 2,2-Dimethyl-7-coumaranyl N-methylcarbamate
    • 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate
    • Caswell No. 160A
    • Carbofuran [ANSI:BSI:ISO]
    • 2,3-Dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate
    • 2,2-Dimethyl-2,3-dihydro-7-benzofuranyl N-methylcarbamate
    • ENT 27,164
    • CHEBI:34611
    • D 1221
    • Furadan 75 WP
    • BAY 78537
    • NIA-10242
    • CCRIS 4017
    • 2,3-Dihydro-2,2-dimethylbenzofuranyl-7-N-methylcarbamate
    • HSDB 1530
    • OMS-864
    • C2292-59A
    • EINECS 216-353-0
    • Carbamic acid, methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
    • 2,2-Dimethyl-2,2-dihydrobenzofuranyl-7 N-methylcarbamate
    • 2,3-Dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate
    • EPA Pesticide Chemical Code 090601
    • NSC 167822
    • 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate
    • BRN 1428746
    • SKF77S6Y67
    • DTXSID9020249
    • AI3-27164
    • Methyl carbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
    • Spectrum_001895
    • SpecPlus_000516
    • 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate
    • Spectrum2_001871
    • Spectrum3_000848
    • Spectrum4_000688
    • Spectrum5_002012
    • NSC-167822
    • Carbamic acid, methyl-, 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl ester
    • Oprea1_828936
    • BSPBio_002435
    • KBioGR_001155
    • KBioSS_002425
    • SPECTRUM330057
    • DivK1c_006612
    • DTXCID70249
    • (2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate
    • SPBio_001742
    • 2,3-Dihydro-2,2-dimethyl-7-benzofuranol N-methylcarbamate
    • C12H15NO3
    • KBio1_001556
    • KBio2_002419
    • KBio2_004987
    • KBio2_007555
    • KBio3_001935
    • 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, 7-(N-methylcarbamate)
    • 5-17-04-00048 (Beilstein Handbook Reference)
    • N-Metylokarbaminian 2,3-dwuwodoro-2,2-dwumetylobenzofuranylu-7 [Polish]
    • NSC167822
    • 2,3-dihydro-2,2-dimethyl-7-benzofuranyl N-methylcarbamate
    • NCGC00094541-01
    • NCGC00094541-02
    • WLN: T56 BOT&J C1 C1 IOVM1
    • C14291
    • 2,2-Dimethyl-2,3-dihydrobenzoduranyl-7-N-methylcarbamate
    • 7-Benzofurano, 2,3-dihydro-2,2-dimethyl, methylcarbamate
    • Diafuran
    • Sunfuran
    • Terafuran
    • Brifer
    • Furadan F
    • Carbofuran [ISO]
    • NEX
    • CAS-1563-66-2
    • UNII-SKF77S6Y67
    • Yaltoxi
    • Tripart nex
    • Carbofuran, 98%
    • Niagaral 242
    • LS-900
    • Furathiocarb metabolite
    • DIAFURAN 5G
    • Sipcam UK carbosip 5G
    • CARBOFURAN [MI]
    • CURATERR 5
    • FURADAN 75WP
    • CARBOFURAN [HSDB]
    • FURADAN SP 50
    • SCHEMBL21656
    • BIDD:ER0379
    • 426008_ALDRICH
    • 45370_RIEDEL
    • CHEMBL416081
    • SCHEMBL21722098
    • 2,3-Dihydro-2,2-dimethyl-7-benzofuranol 7-(N-methylcarbamate)
    • N-Metylokarbaminian 2,3-dwuwodoro-2,2-dwumetylobenzofuranylu-7
    • Tox21_201955
    • Tox21_300623
    • BDBM50064619
    • CCG-39409
    • NIA 10242 75 WP

  • Applications

    Carbofuran (CAS 1563-66-2) is a carbamate insecticide used primarily in agriculture to control pest insects and nematodes on a wide range of crops; typical applications include soil and foliar treatments to suppress pests, seed treatment prior to planting, and use in protected cultivation (greenhouses) for vegetables, fruits, and flowering ornamentals; it is also used for turf and landscape ornamentals such as lawns and shrubs, and may be considered a component in certain pest-management programs, all subject to local regulations and label directions.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 169.13
    methanol 261.13
    isopropanol 116.52
    water 1.04
    ethyl acetate 140.79
    n-propanol 121.36
    acetone 275.01
    n-butanol 114.8
    acetonitrile 150.5
    DMF 788.2
    toluene 32.7
    isobutanol 102.55
    1,4-dioxane 201.54
    methyl acetate 199.71
    THF 356.8
    2-butanone 198.46
    n-pentanol 85.67
    sec-butanol 118.44
    n-hexane 2.36
    ethylene glycol 95.78
    NMP 425.96
    cyclohexane 2.9
    DMSO 455.7
    n-butyl acetate 136.91
    n-octanol 56.87
    chloroform 380.45
    n-propyl acetate 109.78
    acetic acid 255.02
    dichloromethane 340.76
    cyclohexanone 197.73
    propylene glycol 114.81
    isopropyl acetate 104.82
    DMAc 625.87
    2-ethoxyethanol 206.2
    isopentanol 127.44
    n-heptane 1.71
    ethyl formate 138.4
    1,2-dichloroethane 206.98
    n-hexanol 96.96
    2-methoxyethanol 361.74
    isobutyl acetate 93.72
    tetrachloromethane 27.36
    n-pentyl acetate 80.32
    transcutol 391.5
    n-heptanol 49.82
    ethylbenzene 32.34
    MIBK 104.81
    2-propoxyethanol 231.07
    tert-butanol 148.55
    MTBE 116.0
    2-butoxyethanol 124.44
    propionic acid 136.28
    o-xylene 29.47
    formic acid 197.97
    diethyl ether 79.19
    m-xylene 30.87
    p-xylene 44.73
    chlorobenzene 95.55
    dimethyl carbonate 123.25
    n-octane 1.63
    formamide 244.07
    cyclopentanone 275.89
    2-pentanone 139.99
    anisole 114.71
    cyclopentyl methyl ether 111.46
    gamma-butyrolactone 343.61
    1-methoxy-2-propanol 251.89
    pyridine 172.59
    3-pentanone 100.81
    furfural 331.15
    n-dodecane 2.62
    diethylene glycol 238.3
    diisopropyl ether 25.21
    tert-amyl alcohol 141.15
    acetylacetone 206.11
    n-hexadecane 3.0
    acetophenone 125.49
    methyl propionate 143.27
    isopentyl acetate 138.02
    trichloroethylene 443.28
    n-nonanol 48.76
    cyclohexanol 81.69
    benzyl alcohol 116.75
    2-ethylhexanol 55.45
    isooctanol 44.89
    dipropyl ether 35.32
    1,2-dichlorobenzene 104.11
    ethyl lactate 86.14
    propylene carbonate 246.4
    n-methylformamide 289.29
    2-pentanol 75.05
    n-pentane 1.86
    1-propoxy-2-propanol 129.94
    1-methoxy-2-propyl acetate 157.91
    2-(2-methoxypropoxy) propanol 134.86
    mesitylene 19.04
    ε-caprolactone 206.67
    p-cymene 25.56
    epichlorohydrin 410.1
    1,1,1-trichloroethane 139.48
    2-aminoethanol 131.88
    morpholine-4-carbaldehyde 391.55
    sulfolane 378.18
    2,2,4-trimethylpentane 3.2
    2-methyltetrahydrofuran 209.5
    n-hexyl acetate 121.08
    isooctane 2.15
    2-(2-butoxyethoxy)ethanol 163.97
    sec-butyl acetate 84.24
    tert-butyl acetate 112.93
    decalin 4.86
    glycerin 195.82
    diglyme 270.91
    acrylic acid 153.88
    isopropyl myristate 43.84
    n-butyric acid 170.87
    acetyl acetate 121.32
    di(2-ethylhexyl) phthalate 65.57
    ethyl propionate 95.11
    nitromethane 412.54
    1,2-diethoxyethane 107.28
    benzonitrile 125.76
    trioctyl phosphate 44.81
    1-bromopropane 81.25
    gamma-valerolactone 372.19
    n-decanol 36.47
    triethyl phosphate 56.39
    4-methyl-2-pentanol 56.03
    propionitrile 104.12
    vinylene carbonate 217.04
    1,1,2-trichlorotrifluoroethane 309.25
    DMS 142.43
    cumene 28.0
    2-octanol 39.12
    2-hexanone 112.35
    octyl acetate 61.39
    limonene 30.93
    1,2-dimethoxyethane 281.18
    ethyl orthosilicate 50.71
    tributyl phosphate 58.63
    diacetone alcohol 155.11
    N,N-dimethylaniline 80.4
    acrylonitrile 160.6
    aniline 80.22
    1,3-propanediol 171.54
    bromobenzene 89.0
    dibromomethane 190.67
    1,1,2,2-tetrachloroethane 344.51
    2-methyl-cyclohexyl acetate 80.67
    tetrabutyl urea 75.55
    diisobutyl methanol 31.28
    2-phenylethanol 112.39
    styrene 39.17
    dioctyl adipate 69.09
    dimethyl sulfate 217.07
    ethyl butyrate 78.54
    methyl lactate 126.6
    butyl lactate 86.85
    diethyl carbonate 71.58
    propanediol butyl ether 140.56
    triethyl orthoformate 61.19
    p-tert-butyltoluene 24.23
    methyl 4-tert-butylbenzoate 104.5
    morpholine 250.16
    tert-butylamine 68.04
    n-dodecanol 27.82
    dimethoxymethane 277.48
    ethylene carbonate 170.22
    cyrene 149.47
    2-ethoxyethyl acetate 127.68
    2-ethylhexyl acetate 103.04
    1,2,4-trichlorobenzene 132.19
    4-methylpyridine 205.41
    dibutyl ether 43.98
    2,6-dimethyl-4-heptanol 31.28
    DEF 186.36
    dimethyl isosorbide 197.14
    tetrachloroethylene 173.53
    eugenol 121.98
    triacetin 114.96
    span 80 98.53
    1,4-butanediol 91.74
    1,1-dichloroethane 170.26
    2-methyl-1-pentanol 101.97
    methyl formate 242.06
    2-methyl-1-butanol 119.09
    n-decane 3.86
    butyronitrile 111.78
    3,7-dimethyl-1-octanol 60.71
    1-chlorooctane 27.29
    1-chlorotetradecane 11.41
    n-nonane 3.14
    undecane 3.1
    tert-butylcyclohexane 4.68
    cyclooctane 1.2
    cyclopentanol 97.37
    tetrahydropyran 132.3
    tert-amyl methyl ether 93.09
    2,5,8-trioxanonane 185.08
    1-hexene 17.0
    2-isopropoxyethanol 139.31
    2,2,2-trifluoroethanol 138.98
    methyl butyrate 134.53

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction