Carbamide Peroxide

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  • Identifiers

    CAS number
    124-43-6

    Molecular formula
    CH6N2O3

    SMILES
    C(=O)(N)N.OO

    Safety labels

    Oxidizer
    Oxidizer

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 68.67%
    Fishy 31.59%
    Cheesy 22.66%
    Pungent 21.96%
    Savory 21.37%
    Meaty 20.24%
    Cooked 16.49%
    Ripe 15.15%
    Sweet 15.01%
    Sulfurous 14.29%

     

    Flavor
    Odorless 56.5%
    Pungent 27.18%
    Sour 24.65%
    Mousy 23.01%
    Vinegar 22.5%
    Formyl 22.41%
    Mustard 22.19%
    Bland 21.73%
    Soy 20.67%
    Mild 20.57%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    9.27 (weak base)

    Molecular weight
    94.07 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    280°C

    Melting point expt.

    • 167 to 185 °F (decomposes) (NTP, 1992)
    • 75-85

    Flash point

    • 114.8 ˚C est.

    Solubility expt.

    • greater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
    • 500 g/L at °C

  • Synonyms

    • Urea hydrogen peroxide
    • CARBAMIDE PEROXIDE
    • 124-43-6
    • Percarbamide
    • Urea peroxide
    • Urea dioxide
    • Urea hydroperoxide
    • Hydroperit
    • Hydroperite
    • Percarbamid
    • Hyperol
    • Ortizon
    • Perhydrit
    • Thenardol
    • Perhydrol-Urea
    • Hydrogen peroxide urea
    • Hydrogen peroxide carbamide
    • Murine Ear Drops
    • Debrox
    • Gly-oxide
    • Urea compound with hydrogen peroxide (1:1)
    • 31PZ2VAU81
    • DTXSID9024726
    • NSC-24852
    • Carbamide peroxide (USP)
    • Carbamide peroxide [USP]
    • DTXCID804726
    • CHEBI:75178
    • Tilcare
    • SuavEar
    • EarClearRx
    • Earwax Removal
    • Preferred Plus
    • Healthy Ears
    • Carbide Peroxide
    • Ear System
    • Murine Ear
    • Ear Drops Major
    • Wax Out Plus
    • Ear System GNP
    • Ear Wax Kit
    • Earwax Removal Aid
    • Earwax Removal Kit
    • Earwax Removal Drops
    • OPALESCENCE
    • Dr.Whitiss 10%
    • Dr.Whitiss 20%
    • Dr.Whitiss 35%
    • Ear Wax Removal Aid
    • Rexall Earwax Removal
    • EARWAX REM
    • Ear Wax Removal Drops
    • CVS EARWAX REM
    • Deluxe Ear Wash system
    • EARWAX REM CVS
    • RefChem:5647
    • Ear Wax Removal System
    • Ear Wax Removing Drops
    • EAR WAX RMVL
    • Carbamide peroxide drops
    • Hydrogen Peroxide, Urea
    • Clinere Ear Wax Remover
    • CVS Earwax Removal Aid
    • EAR WAX RMVL CVS
    • Carbamide Peroxide 6.5%
    • Carbamide Peroxide-6.5%
    • ERO Ear Wax Removal Kit
    • Meijer Earwax Removal Kit
    • Walgreens Ear Wax Remover
    • CVS EARWAX REM CVS
    • Family Care Earwax Removal
    • Ear Wax Removal Aid Drops
    • EAR WAX RMVL Rite Aid
    • SuavEar Earwax Removal Aid
    • TopCare Earwax Removal Kit
    • LEADER Earwax Removal Kit
    • Otix Ear wax Removal Drops
    • Carbamide Peroxide 6.50%
    • Carbamide Peroxide-6.50%
    • Dr. Whitiss (8.3%)
    • Earwax Removal Drops Equate
    • Lutooth Tooth Whitening Kit
    • Meijer Earwax Removal Drops
    • CareOne Earwax Removal Drops
    • EarWax Removal Kit Rite Aid
    • TopCare Earwax Removal Drops
    • DG Health Earwax Removal kit
    • Ear Drops Earwax Removal Aid
    • Ear Wax Removal Drops Equate
    • Equaline Earwax Removal Drops
    • Murine Ear Wax Removal Drops
    • Tech Care Earwax Removal Kit
    • Hal-Hen Earwax Removal System
    • Rite Aid Earwax Removal Drops
    • CVS Health Earwax Removal Kit
    • Best Choice Earwax Removal Kit
    • carbamide peroxide 6.50% kit
    • Ear Wax Kit Well at Walgreens
    • Tech Care Earwax Removal Drops
    • CARBONYL DIAMINE PEROXIDE
    • ENT Essentials Ear Wax Remvoer
    • Best Choice Earwax Removal Drops
    • Ear Wax Removal System Rite Aid
    • HealthMart Ear Wax Removal Drops
    • WaxRx Ear Wax Removal Aid Drops
    • Ear Wax Removal Drops Up and Up
    • Good Neighbor Pharmacy Ear System
    • Hal Hen Earwax Removal Aid Drops
    • Quality Choice Earwax Removal Kit
    • UREA, COMPOUND WITH H2O2
    • Ear Drops Earwax Removal Aid CVS
    • UREA HYDROGEN PEROXIDE SALT
    • ClearCanal Ear Wax Softerner Drops
    • Harris Teeter Earwax Removal Drops
    • Wax B Gone Ear Wax Removal Drops
    • Quality Choice Earwax Removal Drops
    • UREA, COMPOUNDED WITH H2O2
    • UREA, HYDROGEN PEROXIDE SALT
    • Good Neighbor Pharmacy Earwax Removal
    • Ear Drops (Carbamide Peroxide 6.5%)
    • Foster and Thrive Earwax Removal Drops
    • NeilMed Clear Canal Earwax Removal kit
    • Discount Drug Mart Earwax Removal Drops
    • Audiologists Choice Earwax Removal System
    • Ear Wax Removing Drops Carbamide Peroxide
    • Lucid Hearing Earwax Removal Kit and Bulb
    • Good Neighbor Pharmacy Earwax Removal Drops
    • 124-43-6

  • Applications

    Carbamide Peroxide, CAS 124-43-6, is a compound that decomposes to hydrogen peroxide and urea on contact with water, and it is used as an oxidizing/bleaching agent in a range of formulations. Common applications include: in dental and cosmetic teeth whitening products; in household cleaning and laundry bleaching formulations; in textile bleaching processes; in pulp and paper bleaching; and as a source of hydrogen peroxide for oxidation in industrial and laboratory processes, depending on formulation and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 43.98
    methanol 134.14
    isopropanol 20.64
    water 750.68
    ethyl acetate 9.73
    n-propanol 20.71
    acetone 29.99
    n-butanol 11.66
    acetonitrile 17.19
    DMF 283.81
    toluene 1.13
    isobutanol 11.99
    1,4-dioxane 28.21
    methyl acetate 19.62
    THF 28.95
    2-butanone 12.76
    n-pentanol 8.16
    sec-butanol 10.54
    n-hexane 0.77
    ethylene glycol 127.9
    NMP 87.19
    cyclohexane 0.5
    DMSO 95.06
    n-butyl acetate 6.34
    n-octanol 3.81
    chloroform 2.2
    n-propyl acetate 7.74
    acetic acid 72.13
    dichloromethane 2.75
    cyclohexanone 9.45
    propylene glycol 78.39
    isopropyl acetate 5.66
    DMAc 159.51
    2-ethoxyethanol 47.36
    isopentanol 7.28
    n-heptane 0.71
    ethyl formate 23.52
    1,2-dichloroethane 2.32
    n-hexanol 6.63
    2-methoxyethanol 111.99
    isobutyl acetate 4.71
    tetrachloromethane 1.3
    n-pentyl acetate 4.68
    transcutol 29.12
    n-heptanol 5.33
    ethylbenzene 0.62
    MIBK 4.51
    2-propoxyethanol 42.99
    tert-butanol 14.72
    MTBE 6.2
    2-butoxyethanol 24.87
    propionic acid 36.26
    o-xylene 1.24
    formic acid 210.98
    diethyl ether 7.17
    m-xylene 1.08
    p-xylene 1.0
    chlorobenzene 0.81
    dimethyl carbonate 28.21
    n-octane 0.31
    formamide 164.02
    cyclopentanone 19.17
    2-pentanone 7.82
    anisole 3.63
    cyclopentyl methyl ether 8.75
    gamma-butyrolactone 33.71
    1-methoxy-2-propanol 60.8
    pyridine 9.11
    3-pentanone 6.6
    furfural 40.78
    n-dodecane 0.23
    diethylene glycol 74.47
    diisopropyl ether 1.83
    tert-amyl alcohol 9.14
    acetylacetone 13.03
    n-hexadecane 0.24
    acetophenone 4.74
    methyl propionate 16.95
    isopentyl acetate 4.12
    trichloroethylene 3.02
    n-nonanol 3.49
    cyclohexanol 5.7
    benzyl alcohol 5.73
    2-ethylhexanol 2.94
    isooctanol 3.41
    dipropyl ether 5.49
    1,2-dichlorobenzene 0.81
    ethyl lactate 16.66
    propylene carbonate 17.26
    n-methylformamide 131.67
    2-pentanol 5.69
    n-pentane 0.77
    1-propoxy-2-propanol 22.81
    1-methoxy-2-propyl acetate 11.81
    2-(2-methoxypropoxy) propanol 15.06
    mesitylene 0.8
    ε-caprolactone 12.64
    p-cymene 0.94
    epichlorohydrin 16.53
    1,1,1-trichloroethane 1.43
    2-aminoethanol 90.37
    morpholine-4-carbaldehyde 99.06
    sulfolane 39.54
    2,2,4-trimethylpentane 0.35
    2-methyltetrahydrofuran 10.33
    n-hexyl acetate 4.96
    isooctane 0.24
    2-(2-butoxyethoxy)ethanol 18.42
    sec-butyl acetate 3.71
    tert-butyl acetate 4.99
    decalin 0.28
    glycerin 161.29
    diglyme 39.97
    acrylic acid 51.99
    isopropyl myristate 1.86
    n-butyric acid 19.7
    acetyl acetate 7.28
    di(2-ethylhexyl) phthalate 3.92
    ethyl propionate 7.66
    nitromethane 98.35
    1,2-diethoxyethane 7.15
    benzonitrile 3.47
    trioctyl phosphate 3.16
    1-bromopropane 1.21
    gamma-valerolactone 48.99
    n-decanol 2.55
    triethyl phosphate 4.54
    4-methyl-2-pentanol 3.12
    propionitrile 8.7
    vinylene carbonate 18.52
    1,1,2-trichlorotrifluoroethane 41.61
    DMS 8.32
    cumene 0.7
    2-octanol 2.53
    2-hexanone 5.71
    octyl acetate 3.26
    limonene 1.21
    1,2-dimethoxyethane 52.87
    ethyl orthosilicate 4.02
    tributyl phosphate 3.49
    diacetone alcohol 11.93
    N,N-dimethylaniline 4.16
    acrylonitrile 15.79
    aniline 4.64
    1,3-propanediol 56.7
    bromobenzene 0.43
    dibromomethane 1.46
    1,1,2,2-tetrachloroethane 3.1
    2-methyl-cyclohexyl acetate 3.53
    tetrabutyl urea 5.68
    diisobutyl methanol 1.74
    2-phenylethanol 4.89
    styrene 0.74
    dioctyl adipate 3.85
    dimethyl sulfate 45.31
    ethyl butyrate 5.56
    methyl lactate 42.77
    butyl lactate 10.1
    diethyl carbonate 5.16
    propanediol butyl ether 23.97
    triethyl orthoformate 5.81
    p-tert-butyltoluene 0.96
    methyl 4-tert-butylbenzoate 8.04
    morpholine 34.96
    tert-butylamine 6.32
    n-dodecanol 1.92
    dimethoxymethane 74.05
    ethylene carbonate 15.01
    cyrene 18.54
    2-ethoxyethyl acetate 8.24
    2-ethylhexyl acetate 3.28
    1,2,4-trichlorobenzene 1.2
    4-methylpyridine 7.19
    dibutyl ether 2.25
    2,6-dimethyl-4-heptanol 1.74
    DEF 24.38
    dimethyl isosorbide 16.75
    tetrachloroethylene 3.19
    eugenol 11.92
    triacetin 8.98
    span 80 12.65
    1,4-butanediol 31.07
    1,1-dichloroethane 1.83
    2-methyl-1-pentanol 4.6
    methyl formate 106.18
    2-methyl-1-butanol 7.61
    n-decane 0.36
    butyronitrile 6.37
    3,7-dimethyl-1-octanol 2.27
    1-chlorooctane 0.77
    1-chlorotetradecane 0.42
    n-nonane 0.35
    undecane 0.28
    tert-butylcyclohexane 0.32
    cyclooctane 0.27
    cyclopentanol 11.54
    tetrahydropyran 8.46
    tert-amyl methyl ether 5.1
    2,5,8-trioxanonane 25.36
    1-hexene 1.55
    2-isopropoxyethanol 21.23
    2,2,2-trifluoroethanol 65.0
    methyl butyrate 10.71

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction