Caproyl tyrosine

Overview IFRA Request a quote

  • Identifiers

    CAS number
    30664-77-8

    Molecular formula
    C19H29NO4

    SMILES
    CCCCCCCCCC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 46.88%
    Savory 37.25%
    Herbal 32.29%
    Cooling 31.67%
    Meaty 30.07%
    Spicy 27.92%
    Milky 24.53%
    Citrus 24.43%
    Animal 22.62%
    Mint 22.54%

     

    Flavor
    Odorless 50.28%
    Bland 35.92%
    Mild 35.04%
    Bitter 32.66%
    Herbal 25.23%
    Faint 20.92%
    Sweet-like 20.12%
    Cedarleaf 19.93%
    Lovage 19.75%
    Slightly waxy 19.64%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.4

    pKa est.
    8.33 (weak base)

    Molecular weight
    335.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    532°C

    Flash point

    • 239.74 ˚C est.

  • Synonyms

    • Caproyl tyrosine
    • Caproyl tyrosinic acid
    • L-Tyrosine, N-(1-oxodecyl)-
    • Tyrosine, N-decanoyl-, l-
    • 30664-77-8
    • Caproyl tyrosine [INCI]
    • UNII-VGV84609KH
    • VGV84609KH
    • DTXSID70184705
    • RefChem:123307
    • DTXCID70107196
    • N-decanoyl-l-tyrosine
    • SCHEMBL443219
    • ICCB5_000292
    • Q27291824
    • 30664-77-8

  • Applications

    Caproyl tyrosine is an acylated amino acid derivative that serves primarily as a chemical intermediate and building block in organic synthesis. In pharmaceutical development, it is commonly evaluated as a protected amino acid for peptide synthesis and as a precursor to tyrosine-containing compounds. In cosmetics and personal care, it may be used as a precursor to tyrosine-derived actives or as a lipophilic building block to support formulation of tyrosine-containing formulations. In polymers and plastics, it can function as a functionalized amino acid monomer or building block for tyrosine-containing polymers to tailor surface properties. In coatings, inks, and adhesives, caproyl tyrosine may be explored as a functional additive to introduce reactive groups for crosslinking or to improve compatibility with bio-based components.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 217.46
    methanol 621.83
    isopropanol 83.32
    water 0.39
    ethyl acetate 75.87
    n-propanol 107.12
    acetone 335.96
    n-butanol 58.42
    acetonitrile 29.96
    DMF 547.75
    toluene 7.01
    isobutanol 45.74
    1,4-dioxane 87.96
    methyl acetate 74.0
    THF 270.62
    2-butanone 128.7
    n-pentanol 54.03
    sec-butanol 58.59
    n-hexane 0.37
    ethylene glycol 34.48
    NMP 246.09
    cyclohexane 0.49
    DMSO 1111.08
    n-butyl acetate 37.23
    n-octanol 10.7
    chloroform 19.33
    n-propyl acetate 40.86
    acetic acid 205.57
    dichloromethane 25.25
    cyclohexanone 140.59
    propylene glycol 75.33
    isopropyl acetate 52.36
    DMAc 785.05
    2-ethoxyethanol 251.34
    isopentanol 51.11
    n-heptane 0.3
    ethyl formate 43.16
    1,2-dichloroethane 36.88
    n-hexanol 24.62
    2-methoxyethanol 430.9
    isobutyl acetate 24.21
    tetrachloromethane 3.34
    n-pentyl acetate 24.44
    transcutol 351.0
    n-heptanol 16.1
    ethylbenzene 6.43
    MIBK 48.79
    2-propoxyethanol 137.12
    tert-butanol 101.9
    MTBE 42.22
    2-butoxyethanol 71.33
    propionic acid 84.27
    o-xylene 7.99
    formic acid 137.15
    diethyl ether 20.59
    m-xylene 6.93
    p-xylene 9.07
    chlorobenzene 9.61
    dimethyl carbonate 39.35
    n-octane 0.33
    formamide 308.26
    cyclopentanone 209.49
    2-pentanone 91.71
    anisole 27.98
    cyclopentyl methyl ether 43.64
    gamma-butyrolactone 190.03
    1-methoxy-2-propanol 254.08
    pyridine 54.74
    3-pentanone 47.56
    furfural 114.47
    n-dodecane 0.36
    diethylene glycol 127.96
    diisopropyl ether 5.69
    tert-amyl alcohol 77.53
    acetylacetone 161.51
    n-hexadecane 0.4
    acetophenone 42.85
    methyl propionate 71.86
    isopentyl acetate 40.43
    trichloroethylene 58.97
    n-nonanol 11.67
    cyclohexanol 38.09
    benzyl alcohol 42.43
    2-ethylhexanol 11.76
    isooctanol 14.39
    dipropyl ether 9.28
    1,2-dichlorobenzene 11.67
    ethyl lactate 35.97
    propylene carbonate 72.27
    n-methylformamide 219.44
    2-pentanol 23.96
    n-pentane 0.24
    1-propoxy-2-propanol 74.55
    1-methoxy-2-propyl acetate 75.85
    2-(2-methoxypropoxy) propanol 66.54
    mesitylene 4.33
    ε-caprolactone 101.76
    p-cymene 4.48
    epichlorohydrin 166.82
    1,1,1-trichloroethane 19.3
    2-aminoethanol 123.56
    morpholine-4-carbaldehyde 209.59
    sulfolane 286.54
    2,2,4-trimethylpentane 0.59
    2-methyltetrahydrofuran 81.56
    n-hexyl acetate 27.93
    isooctane 0.39
    2-(2-butoxyethoxy)ethanol 108.14
    sec-butyl acetate 29.09
    tert-butyl acetate 66.55
    decalin 0.83
    glycerin 112.61
    diglyme 201.71
    acrylic acid 64.65
    isopropyl myristate 10.92
    n-butyric acid 105.51
    acetyl acetate 40.03
    di(2-ethylhexyl) phthalate 16.99
    ethyl propionate 33.49
    nitromethane 322.07
    1,2-diethoxyethane 57.93
    benzonitrile 22.67
    trioctyl phosphate 11.4
    1-bromopropane 9.0
    gamma-valerolactone 306.85
    n-decanol 8.8
    triethyl phosphate 17.52
    4-methyl-2-pentanol 17.53
    propionitrile 20.4
    vinylene carbonate 48.69
    1,1,2-trichlorotrifluoroethane 149.49
    DMS 33.87
    cumene 5.59
    2-octanol 8.97
    2-hexanone 48.69
    octyl acetate 15.23
    limonene 5.75
    1,2-dimethoxyethane 220.1
    ethyl orthosilicate 17.42
    tributyl phosphate 14.86
    diacetone alcohol 139.7
    N,N-dimethylaniline 23.84
    acrylonitrile 31.48
    aniline 23.87
    1,3-propanediol 170.3
    bromobenzene 7.71
    dibromomethane 12.26
    1,1,2,2-tetrachloroethane 58.05
    2-methyl-cyclohexyl acetate 27.26
    tetrabutyl urea 24.32
    diisobutyl methanol 8.13
    2-phenylethanol 29.65
    styrene 7.22
    dioctyl adipate 22.21
    dimethyl sulfate 91.9
    ethyl butyrate 25.79
    methyl lactate 74.19
    butyl lactate 36.71
    diethyl carbonate 17.76
    propanediol butyl ether 64.44
    triethyl orthoformate 22.31
    p-tert-butyltoluene 4.56
    methyl 4-tert-butylbenzoate 46.47
    morpholine 172.82
    tert-butylamine 23.57
    n-dodecanol 6.24
    dimethoxymethane 226.24
    ethylene carbonate 42.73
    cyrene 74.14
    2-ethoxyethyl acetate 55.08
    2-ethylhexyl acetate 23.72
    1,2,4-trichlorobenzene 17.5
    4-methylpyridine 48.88
    dibutyl ether 10.68
    2,6-dimethyl-4-heptanol 8.13
    DEF 118.11
    dimethyl isosorbide 102.54
    tetrachloroethylene 35.23
    eugenol 47.25
    triacetin 47.21
    span 80 45.97
    1,4-butanediol 60.95
    1,1-dichloroethane 20.13
    2-methyl-1-pentanol 46.84
    methyl formate 110.63
    2-methyl-1-butanol 46.11
    n-decane 0.57
    butyronitrile 22.12
    3,7-dimethyl-1-octanol 13.11
    1-chlorooctane 3.35
    1-chlorotetradecane 1.63
    n-nonane 0.44
    undecane 0.43
    tert-butylcyclohexane 0.78
    cyclooctane 0.23
    cyclopentanol 56.27
    tetrahydropyran 54.65
    tert-amyl methyl ether 32.9
    2,5,8-trioxanonane 131.65
    1-hexene 3.15
    2-isopropoxyethanol 122.82
    2,2,2-trifluoroethanol 55.81
    methyl butyrate 54.17

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction