(+-)-Cannabichromene

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  • Identifiers

    CAS number
    20675-51-8

    Molecular formula
    C21H30O2

    SMILES
    CCCCCC1=CC(=C2C=CC(OC2=C1)(C)CCC=C(C)C)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fruity 50.67%
    Floral 46.67%
    Spicy 42.17%
    Sweet 32.92%
    Balsamic 29.76%
    Woody 28.84%
    Fresh 24.5%
    Animal 21.79%
    Powdery 20.94%
    Dry 20.83%

     

    Flavor
    Woody 43.38%
    Herbal 38.04%
    Spice 36.32%
    Wood 30.11%
    Spicy 27.55%
    Warm 22.48%
    Fresh 21.53%
    Celery 20.58%
    Thymol 20.51%
    Lovage 20.37%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.9

    pKa est.
    9.56 (weak base)

    Molecular weight
    314.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    425°C

    Flash point

    • 164.67 ˚C est.

  • Synonyms

    • CANNABICHROMENE
    • Cannabichrome
    • 20675-51-8
    • Cannanbichromene
    • Pentylcannabichromene
    • Cannabinochromene
    • K4497H250W
    • NSC-291831
    • 2-Methyl-2-(4-methyl-3-pentenyl)-7-pentyl-2H-1-benzopyran-5-ol
    • 2-methyl-2-(4-methylpent-3-enyl)-7-pentyl-chromen-5-ol
    • DTXSID80942873
    • 18793-28-7
    • (+-)-Cannabichromene
    • RefChem:573726
    • DTXCID801371258
    • (+/-)-Cannabichromene
    • 2-methyl-2-(4-methylpent-3-enyl)-7-pentylchromen-5-ol
    • 2-Methyl-2-(4-methylpent-3-en-1-yl)-7-pentyl-2H-chromen-5-ol
    • CHEMBL422704
    • 2H-1-Benzopyran-5-ol, 2-methyl-2-(4-methyl-3-pentenyl)-7-pentyl-
    • CBC
    • 01 - Active ingredients
    • 2H-1-Benzopyran-5-ol, 2-methyl-2-(4-methyl-3-penten-1-yl)-7-pentyl-
    • Cannabichchromene
    • UNII-K4497H250W
    • Cannabichromene (CBC)
    • 2-Methyl-2-(4-methyl-3-penten-1-yl)-7-pentyl-2H-chromen-5-ol
    • (.+/-.)-Cannabichromene
    • SCHEMBL144938
    • CHEBI:3357
    • orb1297119
    • SCHEMBL29939768
    • (+/-)-Cannabichromene (CBC)
    • GTPL11093
    • GLXC-07022
    • Cannabichromene, 1mg/ml in Methanol
    • 10 - Analysis of active ingredients
    • 11 - Analysis of active ingredients
    • BDBM50318486
    • MFCD00869598
    • NSC291831
    • AKOS032948832
    • DB14735
    • EBC-615687
    • FS-9539
    • 2H-1-Benzopyran-5-ol, (.+-.)-
    • FC172559
    • SY326619
    • NS00018065
    • C08998
    • Cannabichromene - 20 mg/ml solution in methanol
    • Cannabichromene (CBC) 100 microg/mL in Methanol
    • Q410949
    • Cannabichromene (CBC) 1000 microg/mL in Methanol
    • Cannabichromene (CBC) 250 microg/mL in Acetonitrile
    • 2-Methyl-2-(4-methyl-3-pentenyl)-7-pentyl-2H-chromen-5-ol
    • 2-METHYL-2-(4-METHYLPENT-3-ENYL)-7-PENTYL-5-CHROMENOL
    • 2-methyl-2-(4-methyl-3-penten-1-yl)-7-pentyl-2H-1-benzopyran-5-ol
    • 2-Methyl-2-(4-methylpent-3-en-1-yl)-7-pentyl-2H-1-benzopyran-5-ol
    • 2-Methyl-2-(4-methyl-pent-3-enyl)-7-pentyl-2H-chromen-5-ol(cannabichromene)
    • 2H-1-Benzopyran-5-ol, 2-methyl-2-(4-methyl-3-pentenyl)-7-pentyl-, (.+/-.)-
    • 20675-51-8

  • Applications

    (+-)-Cannabichromene, CAS 20675-51-8, is primarily used as an intermediate in the synthesis of other cannabinoids and is studied in cannabinoid chemistry; it can be used as an ingredient in cosmetics and personal care formulations; it may serve as a reference material or starting point for analytical development; and it is evaluated for research applications in pharmaceutical and cannabinoid chemistry, all subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 519.54
    methanol 301.31
    isopropanol 375.8
    water 0.03
    ethyl acetate 894.96
    n-propanol 491.2
    acetone 626.38
    n-butanol 509.93
    acetonitrile 190.46
    DMF 487.76
    toluene 689.75
    isobutanol 343.04
    1,4-dioxane 1523.2
    methyl acetate 561.2
    THF 2059.69
    2-butanone 748.98
    n-pentanol 358.7
    sec-butanol 402.15
    n-hexane 59.5
    ethylene glycol 16.4
    NMP 532.56
    cyclohexane 173.04
    DMSO 474.47
    n-butyl acetate 701.56
    n-octanol 199.72
    chloroform 1778.27
    n-propyl acetate 450.39
    acetic acid 217.21
    dichloromethane 1632.29
    cyclohexanone 1080.77
    propylene glycol 58.64
    isopropyl acetate 580.5
    DMAc 721.6
    2-ethoxyethanol 423.43
    isopentanol 428.47
    n-heptane 50.42
    ethyl formate 257.08
    1,2-dichloroethane 1075.35
    n-hexanol 454.46
    2-methoxyethanol 587.4
    isobutyl acetate 377.92
    tetrachloromethane 154.92
    n-pentyl acetate 450.73
    transcutol 2944.76
    n-heptanol 192.2
    ethylbenzene 237.29
    MIBK 438.53
    2-propoxyethanol 745.14
    tert-butanol 387.06
    MTBE 865.39
    2-butoxyethanol 364.59
    propionic acid 195.52
    o-xylene 271.01
    formic acid 35.35
    diethyl ether 1162.05
    m-xylene 349.87
    p-xylene 296.35
    chlorobenzene 658.18
    dimethyl carbonate 219.51
    n-octane 20.33
    formamide 73.15
    cyclopentanone 899.37
    2-pentanone 735.74
    anisole 468.31
    cyclopentyl methyl ether 962.12
    gamma-butyrolactone 728.82
    1-methoxy-2-propanol 563.3
    pyridine 976.74
    3-pentanone 543.9
    furfural 559.41
    n-dodecane 20.59
    diethylene glycol 287.02
    diisopropyl ether 301.42
    tert-amyl alcohol 386.44
    acetylacetone 673.46
    n-hexadecane 25.58
    acetophenone 367.16
    methyl propionate 605.12
    isopentyl acetate 669.4
    trichloroethylene 1740.23
    n-nonanol 194.33
    cyclohexanol 523.0
    benzyl alcohol 299.87
    2-ethylhexanol 300.07
    isooctanol 171.95
    dipropyl ether 483.24
    1,2-dichlorobenzene 483.63
    ethyl lactate 164.02
    propylene carbonate 443.98
    n-methylformamide 169.88
    2-pentanol 368.84
    n-pentane 61.17
    1-propoxy-2-propanol 542.9
    1-methoxy-2-propyl acetate 705.86
    2-(2-methoxypropoxy) propanol 495.11
    mesitylene 198.44
    ε-caprolactone 841.56
    p-cymene 160.72
    epichlorohydrin 1357.84
    1,1,1-trichloroethane 783.69
    2-aminoethanol 85.73
    morpholine-4-carbaldehyde 830.25
    sulfolane 669.4
    2,2,4-trimethylpentane 44.61
    2-methyltetrahydrofuran 1442.13
    n-hexyl acetate 642.59
    isooctane 34.88
    2-(2-butoxyethoxy)ethanol 739.44
    sec-butyl acetate 381.55
    tert-butyl acetate 571.54
    decalin 72.45
    glycerin 82.25
    diglyme 1266.3
    acrylic acid 122.43
    isopropyl myristate 248.43
    n-butyric acid 502.83
    acetyl acetate 443.79
    di(2-ethylhexyl) phthalate 225.13
    ethyl propionate 380.24
    nitromethane 372.57
    1,2-diethoxyethane 1261.13
    benzonitrile 356.05
    trioctyl phosphate 151.03
    1-bromopropane 741.34
    gamma-valerolactone 1191.85
    n-decanol 143.93
    triethyl phosphate 197.17
    4-methyl-2-pentanol 214.89
    propionitrile 268.15
    vinylene carbonate 373.14
    1,1,2-trichlorotrifluoroethane 534.72
    DMS 446.98
    cumene 151.25
    2-octanol 145.0
    2-hexanone 440.74
    octyl acetate 307.14
    limonene 260.91
    1,2-dimethoxyethane 843.66
    ethyl orthosilicate 216.76
    tributyl phosphate 209.75
    diacetone alcohol 444.3
    N,N-dimethylaniline 270.49
    acrylonitrile 226.99
    aniline 496.05
    1,3-propanediol 232.21
    bromobenzene 790.42
    dibromomethane 1027.29
    1,1,2,2-tetrachloroethane 1429.52
    2-methyl-cyclohexyl acetate 386.24
    tetrabutyl urea 248.72
    diisobutyl methanol 159.49
    2-phenylethanol 380.38
    styrene 311.51
    dioctyl adipate 361.62
    dimethyl sulfate 224.44
    ethyl butyrate 423.26
    methyl lactate 177.14
    butyl lactate 281.45
    diethyl carbonate 269.55
    propanediol butyl ether 324.71
    triethyl orthoformate 351.76
    p-tert-butyltoluene 160.13
    methyl 4-tert-butylbenzoate 346.26
    morpholine 1744.42
    tert-butylamine 256.64
    n-dodecanol 112.7
    dimethoxymethane 893.63
    ethylene carbonate 373.71
    cyrene 295.57
    2-ethoxyethyl acetate 690.91
    2-ethylhexyl acetate 576.45
    1,2,4-trichlorobenzene 599.12
    4-methylpyridine 967.14
    dibutyl ether 432.23
    2,6-dimethyl-4-heptanol 159.49
    DEF 644.43
    dimethyl isosorbide 782.77
    tetrachloroethylene 722.1
    eugenol 310.24
    triacetin 517.91
    span 80 398.0
    1,4-butanediol 77.56
    1,1-dichloroethane 929.01
    2-methyl-1-pentanol 362.65
    methyl formate 131.56
    2-methyl-1-butanol 430.98
    n-decane 36.68
    butyronitrile 387.45
    3,7-dimethyl-1-octanol 258.65
    1-chlorooctane 193.04
    1-chlorotetradecane 80.69
    n-nonane 32.14
    undecane 26.79
    tert-butylcyclohexane 60.6
    cyclooctane 51.95
    cyclopentanol 365.87
    tetrahydropyran 1878.91
    tert-amyl methyl ether 541.2
    2,5,8-trioxanonane 859.12
    1-hexene 239.76
    2-isopropoxyethanol 361.2
    2,2,2-trifluoroethanol 46.64
    methyl butyrate 442.6

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction