Camphor, oxime

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  • Identifiers

    CAS number
    13559-66-5

    Molecular formula
    C10H17NO

    SMILES
    CC1(C2CCC1(C(=NO)C2)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 74.8%
    Herbal 62.48%
    Camphoreous 50.36%
    Pine 47.78%
    Mint 45.17%
    Earthy 44.86%
    Green 44.74%
    Spicy 43.46%
    Fresh 42.79%
    Cooling 39.03%

     

    Flavor
    Woody 73.43%
    Camphor 52.14%
    Herbal 46.37%
    Pine 39.56%
    Balsam 36.36%
    Earthy 34.3%
    Sweet 31.95%
    Spicy 31.19%
    Earth 28.71%
    Green 28.33%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.4

    pKa est.
    7.63 (neutral)

    Molecular weight
    167.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    258°C

    Flash point

    • 102.64 ˚C est.

  • Synonyms

    • RefChem:1080748
    • 13559-66-5
    • Camphor, oxime
    • Camphor oxime
    • D-Camphor oxime
    • (E)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one oxime
    • N-[(2E)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylidene]hydroxylamine
    • 1,7,7-trimethylnorbornan-2-one oxime
    • Maybridge1_002074
    • N-(1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ylidene)hydroxylamine
    • SCHEMBL3081945
    • DTXSID901352069
    • HMS2267K06
    • AKOS016874620
    • DB-047304
    • NS00085673
    • NS00085882
    • F0848-0342
    • (+/-)-1,7,7-trimethyl-bicyclo(2.2.1)heptane-2-one-oxime
    • (+/-)-1,7,7-trimethyl-bicyclo[2,2,1]heptane-2-one-oxime
    • (1S,4R,E)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one oxime
    • 1,7,7-TRIMETHYL-BICYCLO(2.2.1)HEPTAN-2-ONE OXIME
    • (NE)-N-[(1R,4R)-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanylidene]hydroxylamine
    • 13559-66-5

  • Applications

    Camphor, oxime (CAS 13559-66-5) is mainly used as an organic-synthesis intermediate and building block for camphor-derived oximes and related stereochemically complex compounds. In industry and R&D, it is commonly evaluated as a precursor for asymmetric synthesis and as a scaffold for specialty chemicals, including intermediates for pharmaceutical and agrochemical development. It can be used as a chiral auxiliary or ligand-type reagent in certain transformations, and as a precursor in fragrance chemistry to access odor-active camphor-derived derivatives. Its use is typically limited to research, development, and formulation work, and is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 482.7
    methanol 575.57
    isopropanol 492.28
    water 21.23
    ethyl acetate 553.99
    n-propanol 431.39
    acetone 858.13
    n-butanol 329.87
    acetonitrile 541.12
    DMF 1080.9
    toluene 267.7
    isobutanol 311.25
    1,4-dioxane 1169.74
    methyl acetate 687.24
    THF 1271.02
    2-butanone 695.22
    n-pentanol 164.12
    sec-butanol 291.77
    n-hexane 18.06
    ethylene glycol 212.23
    NMP 348.18
    cyclohexane 34.16
    DMSO 745.36
    n-butyl acetate 304.77
    n-octanol 128.57
    chloroform 1259.64
    n-propyl acetate 256.8
    acetic acid 328.67
    dichloromethane 961.23
    cyclohexanone 501.2
    propylene glycol 232.1
    isopropyl acetate 376.69
    DMAc 587.91
    2-ethoxyethanol 445.71
    isopentanol 267.43
    n-heptane 18.52
    ethyl formate 417.48
    1,2-dichloroethane 680.79
    n-hexanol 259.0
    2-methoxyethanol 950.4
    isobutyl acetate 182.07
    tetrachloromethane 301.43
    n-pentyl acetate 205.42
    transcutol 910.31
    n-heptanol 164.17
    ethylbenzene 157.88
    MIBK 304.38
    2-propoxyethanol 680.72
    tert-butanol 485.97
    MTBE 399.97
    2-butoxyethanol 385.97
    propionic acid 312.11
    o-xylene 193.38
    formic acid 256.03
    diethyl ether 401.28
    m-xylene 216.17
    p-xylene 288.24
    chlorobenzene 405.21
    dimethyl carbonate 295.81
    n-octane 12.69
    formamide 523.1
    cyclopentanone 792.1
    2-pentanone 458.12
    anisole 404.49
    cyclopentyl methyl ether 351.25
    gamma-butyrolactone 871.54
    1-methoxy-2-propanol 748.0
    pyridine 669.39
    3-pentanone 365.11
    furfural 787.93
    n-dodecane 10.58
    diethylene glycol 597.0
    diisopropyl ether 128.26
    tert-amyl alcohol 280.17
    acetylacetone 624.56
    n-hexadecane 12.71
    acetophenone 310.6
    methyl propionate 458.09
    isopentyl acetate 294.46
    trichloroethylene 1216.17
    n-nonanol 126.71
    cyclohexanol 196.78
    benzyl alcohol 260.99
    2-ethylhexanol 128.2
    isooctanol 125.62
    dipropyl ether 174.68
    1,2-dichlorobenzene 360.45
    ethyl lactate 157.74
    propylene carbonate 425.29
    n-methylformamide 706.42
    2-pentanol 210.89
    n-pentane 23.77
    1-propoxy-2-propanol 424.21
    1-methoxy-2-propyl acetate 465.8
    2-(2-methoxypropoxy) propanol 270.3
    mesitylene 137.03
    ε-caprolactone 412.46
    p-cymene 99.54
    epichlorohydrin 1095.28
    1,1,1-trichloroethane 770.5
    2-aminoethanol 354.26
    morpholine-4-carbaldehyde 731.4
    sulfolane 652.87
    2,2,4-trimethylpentane 14.65
    2-methyltetrahydrofuran 549.7
    n-hexyl acetate 255.09
    isooctane 16.12
    2-(2-butoxyethoxy)ethanol 381.36
    sec-butyl acetate 191.98
    tert-butyl acetate 392.95
    decalin 22.69
    glycerin 311.45
    diglyme 804.8
    acrylic acid 271.18
    isopropyl myristate 109.83
    n-butyric acid 380.51
    acetyl acetate 385.1
    di(2-ethylhexyl) phthalate 105.05
    ethyl propionate 269.65
    nitromethane 956.79
    1,2-diethoxyethane 382.48
    benzonitrile 348.43
    trioctyl phosphate 79.4
    1-bromopropane 309.24
    gamma-valerolactone 1046.2
    n-decanol 96.47
    triethyl phosphate 111.1
    4-methyl-2-pentanol 146.76
    propionitrile 438.92
    vinylene carbonate 458.26
    1,1,2-trichlorotrifluoroethane 603.51
    DMS 324.85
    cumene 118.38
    2-octanol 106.27
    2-hexanone 260.5
    octyl acetate 136.82
    limonene 100.35
    1,2-dimethoxyethane 794.68
    ethyl orthosilicate 107.2
    tributyl phosphate 90.91
    diacetone alcohol 415.71
    N,N-dimethylaniline 222.97
    acrylonitrile 584.01
    aniline 359.97
    1,3-propanediol 517.84
    bromobenzene 384.9
    dibromomethane 560.24
    1,1,2,2-tetrachloroethane 911.54
    2-methyl-cyclohexyl acetate 164.68
    tetrabutyl urea 109.85
    diisobutyl methanol 93.78
    2-phenylethanol 351.64
    styrene 175.37
    dioctyl adipate 127.12
    dimethyl sulfate 390.18
    ethyl butyrate 213.77
    methyl lactate 282.93
    butyl lactate 177.59
    diethyl carbonate 161.21
    propanediol butyl ether 273.05
    triethyl orthoformate 156.95
    p-tert-butyltoluene 105.26
    methyl 4-tert-butylbenzoate 271.26
    morpholine 1014.1
    tert-butylamine 260.47
    n-dodecanol 73.06
    dimethoxymethane 784.37
    ethylene carbonate 385.43
    cyrene 216.46
    2-ethoxyethyl acetate 344.76
    2-ethylhexyl acetate 202.26
    1,2,4-trichlorobenzene 398.14
    4-methylpyridine 605.98
    dibutyl ether 124.78
    2,6-dimethyl-4-heptanol 93.78
    DEF 370.96
    dimethyl isosorbide 456.26
    tetrachloroethylene 639.86
    eugenol 292.41
    triacetin 239.03
    span 80 214.21
    1,4-butanediol 158.58
    1,1-dichloroethane 745.08
    2-methyl-1-pentanol 136.73
    methyl formate 603.93
    2-methyl-1-butanol 216.67
    n-decane 17.86
    butyronitrile 364.75
    3,7-dimethyl-1-octanol 132.99
    1-chlorooctane 84.75
    1-chlorotetradecane 35.73
    n-nonane 15.64
    undecane 13.51
    tert-butylcyclohexane 23.5
    cyclooctane 14.36
    cyclopentanol 288.8
    tetrahydropyran 591.36
    tert-amyl methyl ether 214.6
    2,5,8-trioxanonane 460.57
    1-hexene 77.64
    2-isopropoxyethanol 290.32
    2,2,2-trifluoroethanol 300.67
    methyl butyrate 314.96

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction