Calcium Glycerophosphate

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  • Identifiers

    CAS number
    27214-00-2

    Molecular formula
    C3H7CaO6P

    SMILES
    C(C(CO)OP(=O)([O-])[O-])O.[Ca+2]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 77.28%
    Sweet 25.8%
    Alcoholic 19.6%
    Clean 18.13%
    Savory 17.8%
    Milky 15.66%
    Buttery 14.7%
    Bitter 14.37%
    Cooling 13.94%
    Sour 12.8%

     

    Flavor
    Odorless 76.26%
    Very mild 28.05%
    Mild 26.78%
    Bland 26.35%
    Sweet-like 25.45%
    Sour 24.66%
    Yeast 21.49%
    Acidic 20.84%
    Very slight 20.56%
    Faint 20.5%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    5.72 (weak acid)

    Molecular weight
    210.14 g/mol

    Melting point expt.

    • Decomposes at 170

    Flash point

    • 162.74 ˚C est.

    Solubility expt.

    • Soluble

  • Synonyms

    • calcium 1,3-dihydroxypropan-2-yl phosphate
    • beta-glycerophosphoric acid calcium salt
    • XWV9Z12C1C
    • 1,2,3-Propanetriol, mono(dihydrogen phosphate) calcium salt
    • CHEBI:31336
    • Glycerol, mono(dihydrogen phosphate), calcium salt (1:1)
    • NEROZIN
    • NEUROSIN
    • PRELIEF
    • Glycerophosphate, Calcium
    • RefChem:573473
    • CALCIUM GLYCERYLPHOSPHATE
    • DTXSID20873177
    • 248-328-5
    • 249-312-0
    • 1,2,3-Propanetriol, mono(dihydrogen phosphate), calcium salt (1:1)
    • 27214-00-2
    • Calcium Glycerophosphate
    • Calcium beta-glycerophosphate
    • 58409-70-4
    • Calcium 2-glycerophosphate
    • Calcium 1,3-hydroxypropyl phosphate
    • Y56W30YB7O
    • DTXSID1048962
    • 1,2,3-Propanetriol, 2-(dihydrogen phosphate), calcium salt (1:1)
    • Glycerol phosphate calcium salt
    • 1,2,3-Propanetriol, mono(dihydrogen phosphate), calcium salt
    • calcium;1,3-dihydroxypropan-2-yl phosphate
    • glycerophosphate calcium
    • NCGC00166037-02
    • UNII-Y56W30YB7O
    • EINECS 261-240-1
    • Calcium glycerophosphoricum
    • UNII-XWV9Z12C1C
    • Calcium glycerino-phosphoricum
    • SCHEMBL290656
    • Calcium glycerophosphate (JAN)
    • CCRIS 1335
    • DTXCID4028888
    • UHHRFSOMMCWGSO-UHFFFAOYSA-L
    • Calcium glycerophosphate [JAN:NF]
    • EINECS 248-328-5
    • Tox21_113398
    • EBC-26206
    • MFCD00037173
    • Calcium 1,3-dihydroxypropyl phosphate
    • AKOS015833122
    • DB11264
    • GLYCERO-2-PHOSPHATE, CALCIUM SALT
    • calcium 2-(phosphonooxy)propane-1,3-diol
    • CAS-58409-70-4
    • NS00081168
    • ST51037276
    • D01488
    • EN300-7719123
    • Q4119838
    • calcium;[2-hydroxy-1-(hydroxymethyl)ethyl] phosphate
    • 1,3-Dihydroxypropan-2-yl dihydrogen phosphate calcium salt
    • CALCIUM 2-HYDROXY-1-(HYDROXYMETHYL)ETHYL PHOSPHATE
    • dihydrogen 2-hydroxy-1-(hydroxymethyl)ethyl phosphate, calcium salt
    • 27214-00-2

  • Applications

    Calcium Glycerophosphate (CAS 27214-00-2) is used as a mineral source providing calcium and phosphate in food processing and dietary supplements, supporting fortification programs. In pharmaceutical formulations, it serves as an excipient and mineral supplement, and can act as a buffering or stabilizing agent in tablets, solutions, or suspensions. In cosmetics and personal care, it functions as a buffering and pH-adjusting agent and as a chelating aid to improve formulation stability. In agriculture, it is used as a calcium and phosphorus source in specialty fertilizers and soil amendments. In coatings, inks, and cleaners, it can act as a chelating/sequestering agent to improve product stability and control metal ions. It may also be encountered as an intermediate or additive in various industrial formulations, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 134.91
    methanol 372.19
    isopropanol 74.16
    water 570.72
    ethyl acetate 15.98
    n-propanol 62.2
    acetone 108.84
    n-butanol 46.25
    acetonitrile 41.28
    DMF 603.97
    toluene 7.21
    isobutanol 23.15
    1,4-dioxane 84.96
    methyl acetate 27.88
    THF 97.41
    2-butanone 33.62
    n-pentanol 20.85
    sec-butanol 37.32
    n-hexane 1.45
    ethylene glycol 320.06
    NMP 283.22
    cyclohexane 7.99
    DMSO 1025.57
    n-butyl acetate 9.11
    n-octanol 17.36
    chloroform 9.0
    n-propyl acetate 7.62
    acetic acid 61.08
    dichloromethane 18.56
    cyclohexanone 38.2
    propylene glycol 122.14
    isopropyl acetate 9.07
    DMAc 301.2
    2-ethoxyethanol 138.33
    isopentanol 22.11
    n-heptane 4.32
    ethyl formate 41.31
    1,2-dichloroethane 32.39
    n-hexanol 23.54
    2-methoxyethanol 430.22
    isobutyl acetate 1.94
    tetrachloromethane 4.83
    n-pentyl acetate 9.94
    transcutol 108.22
    n-heptanol 18.05
    ethylbenzene 3.46
    MIBK 10.63
    2-propoxyethanol 83.68
    tert-butanol 69.47
    MTBE 17.17
    2-butoxyethanol 51.96
    propionic acid 31.97
    o-xylene 10.64
    formic acid 360.85
    diethyl ether 26.94
    m-xylene 6.11
    p-xylene 3.66
    chlorobenzene 4.76
    dimethyl carbonate 29.53
    n-octane 2.14
    formamide 531.19
    cyclopentanone 55.35
    2-pentanone 28.22
    anisole 11.18
    cyclopentyl methyl ether 24.42
    gamma-butyrolactone 65.75
    1-methoxy-2-propanol 177.03
    pyridine 33.02
    3-pentanone 19.13
    furfural 96.34
    n-dodecane 1.49
    diethylene glycol 176.29
    diisopropyl ether 5.15
    tert-amyl alcohol 40.05
    acetylacetone 37.61
    n-hexadecane 1.62
    acetophenone 15.81
    methyl propionate 26.46
    isopentyl acetate 5.54
    trichloroethylene 20.14
    n-nonanol 15.64
    cyclohexanol 32.21
    benzyl alcohol 22.72
    2-ethylhexanol 9.07
    isooctanol 9.45
    dipropyl ether 11.38
    1,2-dichlorobenzene 6.71
    ethyl lactate 17.33
    propylene carbonate 20.12
    n-methylformamide 298.06
    2-pentanol 23.06
    n-pentane 4.44
    1-propoxy-2-propanol 43.26
    1-methoxy-2-propyl acetate 17.15
    2-(2-methoxypropoxy) propanol 40.55
    mesitylene 5.68
    ε-caprolactone 28.65
    p-cymene 5.12
    epichlorohydrin 69.96
    1,1,1-trichloroethane 6.2
    2-aminoethanol 221.86
    morpholine-4-carbaldehyde 218.34
    sulfolane 152.23
    2,2,4-trimethylpentane 1.07
    2-methyltetrahydrofuran 34.87
    n-hexyl acetate 12.09
    isooctane 0.7
    2-(2-butoxyethoxy)ethanol 61.9
    sec-butyl acetate 3.34
    tert-butyl acetate 10.71
    decalin 1.31
    glycerin 273.69
    diglyme 110.83
    acrylic acid 44.67
    isopropyl myristate 5.31
    n-butyric acid 27.02
    acetyl acetate 9.79
    di(2-ethylhexyl) phthalate 8.37
    ethyl propionate 7.76
    nitromethane 146.2
    1,2-diethoxyethane 21.39
    benzonitrile 12.64
    trioctyl phosphate 8.18
    1-bromopropane 9.46
    gamma-valerolactone 104.99
    n-decanol 12.27
    triethyl phosphate 7.41
    4-methyl-2-pentanol 8.42
    propionitrile 18.81
    vinylene carbonate 21.25
    1,1,2-trichlorotrifluoroethane 94.3
    DMS 11.06
    cumene 2.57
    2-octanol 10.78
    2-hexanone 9.25
    octyl acetate 8.82
    limonene 7.63
    1,2-dimethoxyethane 135.06
    ethyl orthosilicate 6.57
    tributyl phosphate 6.78
    diacetone alcohol 40.78
    N,N-dimethylaniline 15.11
    acrylonitrile 36.93
    aniline 20.53
    1,3-propanediol 197.16
    bromobenzene 3.58
    dibromomethane 12.97
    1,1,2,2-tetrachloroethane 28.66
    2-methyl-cyclohexyl acetate 6.22
    tetrabutyl urea 16.4
    diisobutyl methanol 6.58
    2-phenylethanol 19.81
    styrene 3.7
    dioctyl adipate 8.67
    dimethyl sulfate 72.0
    ethyl butyrate 7.71
    methyl lactate 60.98
    butyl lactate 15.27
    diethyl carbonate 5.86
    propanediol butyl ether 51.27
    triethyl orthoformate 7.29
    p-tert-butyltoluene 5.68
    methyl 4-tert-butylbenzoate 24.64
    morpholine 104.86
    tert-butylamine 26.61
    n-dodecanol 9.48
    dimethoxymethane 180.2
    ethylene carbonate 17.58
    cyrene 42.27
    2-ethoxyethyl acetate 16.63
    2-ethylhexyl acetate 4.38
    1,2,4-trichlorobenzene 7.4
    4-methylpyridine 25.42
    dibutyl ether 7.5
    2,6-dimethyl-4-heptanol 6.58
    DEF 69.23
    dimethyl isosorbide 48.01
    tetrachloroethylene 27.21
    eugenol 31.22
    triacetin 14.48
    span 80 30.57
    1,4-butanediol 79.18
    1,1-dichloroethane 9.1
    2-methyl-1-pentanol 10.36
    methyl formate 185.59
    2-methyl-1-butanol 19.81
    n-decane 2.25
    butyronitrile 17.07
    3,7-dimethyl-1-octanol 9.59
    1-chlorooctane 5.61
    1-chlorotetradecane 2.83
    n-nonane 2.24
    undecane 1.8
    tert-butylcyclohexane 0.76
    cyclooctane 3.73
    cyclopentanol 43.71
    tetrahydropyran 30.35
    tert-amyl methyl ether 16.84
    2,5,8-trioxanonane 89.33
    1-hexene 2.68
    2-isopropoxyethanol 46.64
    2,2,2-trifluoroethanol 66.55
    methyl butyrate 12.66

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction