Cadinane

Overview IFRA Request a quote

  • Identifiers

    CAS number
    483-73-8

    Molecular formula
    C15H28

    SMILES
    C[C@H]1CC[C@H]2[C@H](CC[C@H]([C@@H]2C1)C(C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 60.2%
    Herbal 54.31%
    Spicy 52.96%
    Fresh 49.03%
    Citrus 41.64%
    Green 39.05%
    Pine 35.2%
    Dry 33.45%
    Terpenic 32.2%
    Mint 31.43%

     

    Flavor
    Woody 34.43%
    Herb 31.99%
    Wood 31.08%
    Spice 30.97%
    Pine 27.6%
    Herbal 24.75%
    Sweet 23.61%
    Fir needle 23.53%
    Green 22.8%
    Terpene 22.76%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    6.2

    pKa est.
    9.72 (weak base)

    Molecular weight
    208.38 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    259°C

    Flash point

    • 98.44 ˚C est.

  • Synonyms

    • Cadinane
    • 483-73-8
    • CHEBI:36513
    • DTXSID301020553
    • (1S,4S,4aS,6S,8aS)-1,6-dimethyl-4-propan-2-yl-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalene
    • RefChem:122552
    • DTXCID901478320
    • (1S,4S,4aS,6S,8aS)-4-isopropyl-1,6-dimethyldecahydronaphthalene
    • (1S,4S,4aS,6S,8aS)-1,6-dimethyl-4-(propan-2-yl)decahydronaphthalene
    • SCHEMBL29449737
    • Q27116864
    • [1S-(1I+/-,4I+/-,4aI+/-,6I+/-,8aI(2))]-decahydro-1,6-dimethyl-4- (1-methylethyl)naphthalene
    • 483-73-8

  • Applications

    Cadinane (CAS 483-73-8) is a sesquiterpene hydrocarbon primarily used as a fragrance component in perfumery and may function as a scent fixative to help sustain and blend woody–spicy notes. It is commonly evaluated as an ingredient in cosmetics/personal care for its fragrance contribution and can be incorporated into household products such as air fresheners and scented cleaners to impart lasting aroma. In industrial manufacturing, cadinane may serve as an intermediate or building block for the synthesis of other sesquiterpene derivatives used in fragrances and specialty chemicals. It may also be considered as an aroma additive in coatings or inks, subject to formulation limits and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 210.57
    methanol 66.26
    isopropanol 298.99
    water 0.03
    ethyl acetate 711.77
    n-propanol 308.61
    acetone 662.01
    n-butanol 399.67
    acetonitrile 311.09
    DMF 339.02
    toluene 1056.92
    isobutanol 289.8
    1,4-dioxane 1593.47
    methyl acetate 478.43
    THF 3118.45
    2-butanone 751.87
    n-pentanol 239.95
    sec-butanol 324.1
    n-hexane 508.48
    ethylene glycol 9.12
    NMP 526.9
    cyclohexane 1171.47
    DMSO 270.03
    n-butyl acetate 1776.73
    n-octanol 385.49
    chloroform 1389.23
    n-propyl acetate 547.41
    acetic acid 115.31
    dichloromethane 1333.38
    cyclohexanone 1553.63
    propylene glycol 28.65
    isopropyl acetate 610.65
    DMAc 324.92
    2-ethoxyethanol 173.27
    isopentanol 416.42
    n-heptane 1080.42
    ethyl formate 324.28
    1,2-dichloroethane 960.93
    n-hexanol 847.68
    2-methoxyethanol 238.34
    isobutyl acetate 473.46
    tetrachloromethane 434.44
    n-pentyl acetate 696.16
    transcutol 882.61
    n-heptanol 400.45
    ethylbenzene 456.0
    MIBK 558.61
    2-propoxyethanol 608.98
    tert-butanol 444.67
    MTBE 956.8
    2-butoxyethanol 374.22
    propionic acid 163.21
    o-xylene 534.8
    formic acid 8.05
    diethyl ether 1120.64
    m-xylene 665.1
    p-xylene 564.5
    chlorobenzene 808.64
    dimethyl carbonate 131.7
    n-octane 271.9
    formamide 20.06
    cyclopentanone 1545.12
    2-pentanone 788.92
    anisole 527.77
    cyclopentyl methyl ether 1392.54
    gamma-butyrolactone 1096.9
    1-methoxy-2-propanol 279.37
    pyridine 1196.25
    3-pentanone 601.87
    furfural 610.32
    n-dodecane 136.47
    diethylene glycol 142.35
    diisopropyl ether 501.77
    tert-amyl alcohol 382.92
    acetylacetone 650.44
    n-hexadecane 167.05
    acetophenone 392.4
    methyl propionate 408.82
    isopentyl acetate 1390.74
    trichloroethylene 1305.75
    n-nonanol 360.44
    cyclohexanol 689.56
    benzyl alcohol 247.1
    2-ethylhexanol 858.84
    isooctanol 357.14
    dipropyl ether 1886.97
    1,2-dichlorobenzene 606.04
    ethyl lactate 120.58
    propylene carbonate 659.19
    n-methylformamide 118.33
    2-pentanol 359.44
    n-pentane 431.04
    1-propoxy-2-propanol 755.75
    1-methoxy-2-propyl acetate 814.05
    2-(2-methoxypropoxy) propanol 313.57
    mesitylene 503.88
    ε-caprolactone 1048.96
    p-cymene 614.46
    epichlorohydrin 1167.94
    1,1,1-trichloroethane 1126.52
    2-aminoethanol 35.7
    morpholine-4-carbaldehyde 537.47
    sulfolane 856.68
    2,2,4-trimethylpentane 169.51
    2-methyltetrahydrofuran 2140.02
    n-hexyl acetate 798.66
    isooctane 175.35
    2-(2-butoxyethoxy)ethanol 444.58
    sec-butyl acetate 410.48
    tert-butyl acetate 694.08
    decalin 318.38
    glycerin 31.1
    diglyme 918.24
    acrylic acid 90.19
    isopropyl myristate 432.67
    n-butyric acid 420.03
    acetyl acetate 385.14
    di(2-ethylhexyl) phthalate 235.92
    ethyl propionate 432.7
    nitromethane 222.52
    1,2-diethoxyethane 1105.2
    benzonitrile 490.52
    trioctyl phosphate 226.39
    1-bromopropane 1114.95
    gamma-valerolactone 1206.02
    n-decanol 275.5
    triethyl phosphate 326.51
    4-methyl-2-pentanol 257.85
    propionitrile 464.02
    vinylene carbonate 479.57
    1,1,2-trichlorotrifluoroethane 298.83
    DMS 342.67
    cumene 324.32
    2-octanol 312.31
    2-hexanone 603.72
    octyl acetate 450.99
    limonene 988.66
    1,2-dimethoxyethane 745.06
    ethyl orthosilicate 360.5
    tributyl phosphate 269.61
    diacetone alcohol 410.67
    N,N-dimethylaniline 344.5
    acrylonitrile 310.36
    aniline 525.08
    1,3-propanediol 109.13
    bromobenzene 1049.29
    dibromomethane 1191.97
    1,1,2,2-tetrachloroethane 1000.48
    2-methyl-cyclohexyl acetate 668.06
    tetrabutyl urea 326.67
    diisobutyl methanol 549.96
    2-phenylethanol 464.57
    styrene 516.32
    dioctyl adipate 411.01
    dimethyl sulfate 150.81
    ethyl butyrate 1023.13
    methyl lactate 97.92
    butyl lactate 311.42
    diethyl carbonate 517.77
    propanediol butyl ether 211.71
    triethyl orthoformate 708.41
    p-tert-butyltoluene 595.04
    methyl 4-tert-butylbenzoate 424.64
    morpholine 1433.42
    tert-butylamine 456.07
    n-dodecanol 223.83
    dimethoxymethane 457.51
    ethylene carbonate 508.55
    cyrene 251.89
    2-ethoxyethyl acetate 579.48
    2-ethylhexyl acetate 1274.75
    1,2,4-trichlorobenzene 636.26
    4-methylpyridine 1143.06
    dibutyl ether 1056.55
    2,6-dimethyl-4-heptanol 549.96
    DEF 569.53
    dimethyl isosorbide 772.62
    tetrachloroethylene 620.95
    eugenol 283.17
    triacetin 417.53
    span 80 356.64
    1,4-butanediol 39.05
    1,1-dichloroethane 971.49
    2-methyl-1-pentanol 257.82
    methyl formate 114.78
    2-methyl-1-butanol 352.57
    n-decane 268.33
    butyronitrile 701.44
    3,7-dimethyl-1-octanol 435.72
    1-chlorooctane 591.52
    1-chlorotetradecane 230.71
    n-nonane 304.33
    undecane 183.42
    tert-butylcyclohexane 268.84
    cyclooctane 504.76
    cyclopentanol 608.52
    tetrahydropyran 2669.95
    tert-amyl methyl ether 621.98
    2,5,8-trioxanonane 561.92
    1-hexene 822.97
    2-isopropoxyethanol 190.28
    2,2,2-trifluoroethanol 34.9
    methyl butyrate 583.14

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction